Motif ID: Osr2_Osr1

Z-value: 1.095

Transcription factors associated with Osr2_Osr1:

Gene SymbolEntrez IDGene Name
Osr1 ENSMUSG00000048387.7 Osr1
Osr2 ENSMUSG00000022330.4 Osr2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Osr1mm10_v2_chr12_+_9574437_95744480.288.5e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Osr2_Osr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_80128834 6.251 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr4_+_13743424 5.605 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_90203980 5.518 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr6_-_144209471 3.899 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr6_-_144209448 3.874 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr6_-_144209558 3.428 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr4_+_102087543 3.238 ENSMUST00000106911.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_-_57509995 2.922 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr6_-_59024470 2.749 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr19_-_41206774 2.718 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr9_-_16378231 2.621 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr2_+_136892168 2.596 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr10_-_63927434 2.501 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr7_-_123500449 2.447 ENSMUST00000042470.7
ENSMUST00000128217.1
Zkscan2

zinc finger with KRAB and SCAN domains 2

chr6_-_59024340 2.429 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr19_-_14598031 2.361 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_+_27217011 2.334 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr19_-_14597983 2.312 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr4_-_134254076 2.256 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr10_-_109823585 2.195 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr3_-_89322883 2.019 ENSMUST00000029673.5
Efna3
ephrin A3
chr3_-_127225847 1.834 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr3_-_127225917 1.745 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr14_-_20480106 1.730 ENSMUST00000065504.9
ENSMUST00000100844.4
Anxa7

annexin A7

chr4_+_135963742 1.711 ENSMUST00000149636.1
ENSMUST00000143304.1
Gale

galactose-4-epimerase, UDP

chr5_+_107497762 1.631 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr4_+_43383449 1.584 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr18_-_70141568 1.575 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chr9_+_49102720 1.547 ENSMUST00000070390.5
ENSMUST00000167095.1
Tmprss5

transmembrane protease, serine 5 (spinesin)

chr4_+_135963720 1.481 ENSMUST00000102541.3
Gale
galactose-4-epimerase, UDP
chr9_+_3532295 1.441 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr6_+_37900477 1.411 ENSMUST00000120238.1
Trim24
tripartite motif-containing 24
chr5_+_107497718 1.403 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr12_-_75177325 1.364 ENSMUST00000042299.2
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr3_+_145576196 1.320 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr5_+_76529303 1.262 ENSMUST00000087133.4
ENSMUST00000113493.1
ENSMUST00000049469.6
Exoc1


exocyst complex component 1


chr16_+_91729281 1.222 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chrX_+_170010744 1.170 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr2_+_35622160 1.157 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr9_-_86546795 1.124 ENSMUST00000167814.1
Gm17530
predicted gene, 17530
chr2_+_122028544 1.096 ENSMUST00000028668.7
Eif3j1
eukaryotic translation initiation factor 3, subunit J1
chr16_+_91729436 1.080 ENSMUST00000113993.1
Itsn1
intersectin 1 (SH3 domain protein 1A)
chr10_-_57532416 1.075 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr8_+_25720054 1.066 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr5_-_112589990 1.061 ENSMUST00000183186.1
ENSMUST00000182949.1
1700034G24Rik

RIKEN cDNA 1700034G24 gene

chr12_-_110682606 1.005 ENSMUST00000070659.5
1700001K19Rik
RIKEN cDNA 1700001K19 gene
chr2_+_83644435 1.004 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr7_-_119720742 1.004 ENSMUST00000033236.7
Thumpd1
THUMP domain containing 1
chr4_-_119383732 1.001 ENSMUST00000044781.2
ENSMUST00000084307.3
Ccdc30

coiled-coil domain containing 30

chrY_+_90785442 0.968 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr13_+_4191163 0.943 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr7_+_97842917 0.941 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr2_+_35622010 0.933 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr12_+_70974621 0.933 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr6_-_142571303 0.921 ENSMUST00000032374.7
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
chr15_-_78718113 0.912 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr18_-_31317043 0.908 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr9_+_108508005 0.899 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr10_-_57532489 0.889 ENSMUST00000020027.4
Serinc1
serine incorporator 1
chr12_-_70231414 0.882 ENSMUST00000161083.1
Pygl
liver glycogen phosphorylase
chr6_+_57702601 0.846 ENSMUST00000072954.1
ENSMUST00000050077.8
Lancl2

LanC (bacterial lantibiotic synthetase component C)-like 2

chr7_+_97720839 0.802 ENSMUST00000070021.1
Gm9990
predicted gene 9990
chr2_-_156180135 0.777 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr11_-_115001880 0.764 ENSMUST00000092464.3
AF251705
cDNA sequence AF251705
chr2_+_153741274 0.758 ENSMUST00000028981.8
Mapre1
microtubule-associated protein, RP/EB family, member 1
chr2_+_172248492 0.740 ENSMUST00000038532.1
Mc3r
melanocortin 3 receptor
chr9_-_50739365 0.737 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr15_-_27681498 0.737 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr6_+_57703051 0.726 ENSMUST00000151042.1
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr10_+_4611971 0.706 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr12_-_108702265 0.682 ENSMUST00000167978.1
ENSMUST00000021691.4
Degs2

degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase

chr9_+_87022014 0.672 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr11_-_102556122 0.669 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr10_+_74967164 0.667 ENSMUST00000037813.4
Gnaz
guanine nucleotide binding protein, alpha z subunit
chr7_-_127890918 0.651 ENSMUST00000121394.1
Prss53
protease, serine, 53
chr1_-_125913101 0.633 ENSMUST00000161361.1
Lypd1
Ly6/Plaur domain containing 1
chr15_+_35371498 0.629 ENSMUST00000048646.7
Vps13b
vacuolar protein sorting 13B (yeast)
chr9_-_45906837 0.626 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
Rnf214


ring finger protein 214


chr4_+_134496966 0.613 ENSMUST00000134506.1
ENSMUST00000136171.1
ENSMUST00000125330.1
Paqr7


progestin and adipoQ receptor family member VII


chr6_+_11925869 0.601 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr9_-_104262900 0.600 ENSMUST00000035170.6
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr16_-_91728701 0.597 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr8_+_3621529 0.596 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr4_+_134496996 0.587 ENSMUST00000095074.3
Paqr7
progestin and adipoQ receptor family member VII
chr5_+_105876532 0.554 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr8_+_45975514 0.524 ENSMUST00000034051.6
Ufsp2
UFM1-specific peptidase 2
chr15_+_84232030 0.524 ENSMUST00000023072.6
Parvb
parvin, beta
chr10_-_39899238 0.522 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr4_-_116627921 0.520 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr18_+_38296805 0.512 ENSMUST00000171461.1
Rnf14
ring finger protein 14
chr15_-_20666750 0.503 ENSMUST00000052910.4
Acot10
acyl-CoA thioesterase 10
chr4_-_58499398 0.495 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr15_+_78935177 0.492 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr8_+_9864251 0.489 ENSMUST00000088080.2
Gm10217
predicted gene 10217
chr7_+_96951505 0.478 ENSMUST00000044466.5
Nars2
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
chrY_-_6681243 0.469 ENSMUST00000115940.1
Gm21719
predicted gene, 21719
chr10_+_3740348 0.468 ENSMUST00000120274.1
Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr11_+_72301613 0.461 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1


XIAP associated factor 1


chr6_+_87887814 0.460 ENSMUST00000113607.3
ENSMUST00000049966.5
Copg1

coatomer protein complex, subunit gamma 1

chr2_+_176831140 0.440 ENSMUST00000122218.2
ENSMUST00000126726.1
Gm14408

predicted gene 14408

chr12_+_84114321 0.434 ENSMUST00000123491.1
ENSMUST00000046340.2
ENSMUST00000136159.1
Dnal1


dynein, axonemal, light chain 1


chr15_-_43869993 0.428 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr9_-_53610329 0.425 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr1_-_179546261 0.421 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr6_-_89595647 0.401 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr6_+_117906755 0.398 ENSMUST00000170346.1
ENSMUST00000179224.1
ENSMUST00000035493.7
Hnrnpf


heterogeneous nuclear ribonucleoprotein F


chr11_+_80209019 0.395 ENSMUST00000077451.7
ENSMUST00000055056.9
Rhot1

ras homolog gene family, member T1

chr2_+_164562579 0.380 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr7_+_96951552 0.369 ENSMUST00000107159.1
Nars2
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
chr12_-_115790884 0.366 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr9_-_7184440 0.358 ENSMUST00000140466.1
Dync2h1
dynein cytoplasmic 2 heavy chain 1
chr16_-_20425881 0.353 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr16_-_18413452 0.349 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt

catechol-O-methyltransferase

chr19_+_20601958 0.345 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr10_+_77829467 0.343 ENSMUST00000092368.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr11_-_94507337 0.340 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr8_+_27023793 0.327 ENSMUST00000033873.7
Erlin2
ER lipid raft associated 2
chr5_+_123930675 0.312 ENSMUST00000094320.3
ENSMUST00000165148.1
Ccdc62

coiled-coil domain containing 62

chr10_+_127501672 0.295 ENSMUST00000160019.1
ENSMUST00000160610.1
Stac3

SH3 and cysteine rich domain 3

chr8_-_45975224 0.294 ENSMUST00000095323.1
ENSMUST00000098786.2
1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr1_-_181183739 0.278 ENSMUST00000159290.1
Wdr26
WD repeat domain 26
chr6_+_117906809 0.276 ENSMUST00000177918.1
ENSMUST00000163168.2
Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr10_+_77864623 0.271 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr13_-_40733768 0.270 ENSMUST00000110193.2
Tfap2a
transcription factor AP-2, alpha
chr11_+_9048575 0.270 ENSMUST00000043285.4
Gm11992
predicted gene 11992
chr11_+_75588064 0.268 ENSMUST00000143219.1
ENSMUST00000179521.1
ENSMUST00000179445.1
Pitpna


phosphatidylinositol transfer protein, alpha


chr16_-_91728599 0.254 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr1_+_44119952 0.254 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chrY_+_90784738 0.254 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr2_-_175175871 0.253 ENSMUST00000109054.2
Gm14443
predicted gene 14443
chr8_+_12984246 0.252 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr14_-_123627059 0.245 ENSMUST00000000201.5
Nalcn
sodium leak channel, non-selective
chr2_-_33087169 0.244 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr10_+_127501707 0.219 ENSMUST00000035839.2
Stac3
SH3 and cysteine rich domain 3
chr11_-_100759942 0.216 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr8_-_22653406 0.214 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr5_-_113650390 0.198 ENSMUST00000047936.6
Cmklr1
chemokine-like receptor 1
chr19_-_6067785 0.197 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chr11_-_100759740 0.188 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_-_116627478 0.186 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr2_-_104028287 0.185 ENSMUST00000056170.3
4931422A03Rik
RIKEN cDNA 4931422A03 gene
chr4_+_3940747 0.177 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_-_138913915 0.175 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr1_+_171270321 0.171 ENSMUST00000064272.3
ENSMUST00000141999.1
ENSMUST00000111313.3
B4galt3


UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3


chr14_+_44102654 0.169 ENSMUST00000074839.6
Ear2
eosinophil-associated, ribonuclease A family, member 2
chr1_+_179546303 0.151 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr3_-_95357156 0.146 ENSMUST00000107171.3
ENSMUST00000015841.5
ENSMUST00000107170.2
Setdb1


SET domain, bifurcated 1


chr3_-_116614587 0.135 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr7_+_125603420 0.134 ENSMUST00000033000.6
Il21r
interleukin 21 receptor
chr2_-_177925604 0.128 ENSMUST00000108934.2
ENSMUST00000081529.4
C330013J21Rik

RIKEN cDNA C330013J21 gene

chr7_-_127875633 0.122 ENSMUST00000106261.1
ENSMUST00000144721.1
Zfp668

zinc finger protein 668

chr15_+_89429560 0.121 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr7_+_119561699 0.116 ENSMUST00000167935.2
ENSMUST00000130583.1
Acsm2

acyl-CoA synthetase medium-chain family member 2

chr4_-_116555896 0.115 ENSMUST00000069674.5
ENSMUST00000106478.2
Tmem69

transmembrane protein 69

chr9_-_48495321 0.108 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr14_-_70599832 0.103 ENSMUST00000022690.9
Fam160b2
family with sequence similarity 160, member B2
chrX_-_7947553 0.103 ENSMUST00000133349.1
Hdac6
histone deacetylase 6
chr4_-_136021722 0.101 ENSMUST00000030427.5
Tceb3
transcription elongation factor B (SIII), polypeptide 3
chr16_-_91728975 0.088 ENSMUST00000073466.6
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr16_+_17070281 0.077 ENSMUST00000090199.3
Ypel1
yippee-like 1 (Drosophila)
chr1_-_105659008 0.077 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr12_-_111712909 0.073 ENSMUST00000160576.1
Bag5
BCL2-associated athanogene 5
chr10_+_82058417 0.053 ENSMUST00000105313.1
Zfp873
zinc finger protein 873
chr7_+_126950687 0.051 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr9_-_96719404 0.051 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr3_+_96645579 0.042 ENSMUST00000119365.1
ENSMUST00000029744.5
Itga10

integrin, alpha 10

chr2_-_67194695 0.041 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr1_+_87404916 0.027 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr16_+_91391721 0.015 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr2_-_5862923 0.013 ENSMUST00000071016.2
Gm13199
predicted gene 13199
chr2_+_144368961 0.011 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)
chr4_+_130913120 0.011 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr6_+_51523901 0.009 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr9_+_7184514 0.006 ENSMUST00000034499.8
Dcun1d5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr6_+_91473695 0.003 ENSMUST00000032183.4
Tmem43
transmembrane protein 43
chr5_+_124540695 0.000 ENSMUST00000060226.4
Tmed2
transmembrane emp24 domain trafficking protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.8 3.2 GO:0061623 glycolytic process from galactose(GO:0061623)
0.5 2.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.5 1.6 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.5 4.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 2.0 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.4 3.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 6.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 0.9 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 1.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 2.0 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 3.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.7 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.2 0.7 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.3 GO:0048254 snoRNA localization(GO:0048254)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.8 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 0.9 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.2 0.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 0.9 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.2 5.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.4 GO:0006550 isoleucine catabolic process(GO:0006550) acetyl-CoA catabolic process(GO:0046356) ketone body catabolic process(GO:0046952)
0.1 0.3 GO:0021557 oculomotor nerve development(GO:0021557)
0.1 1.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 2.6 GO:0010842 retina layer formation(GO:0010842)
0.1 1.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 4.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.5 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.4 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0043486 histone exchange(GO:0043486)
0.0 2.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0035094 synaptic transmission, cholinergic(GO:0007271) response to nicotine(GO:0035094)
0.0 0.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.2 GO:0048477 oogenesis(GO:0048477)
0.0 0.7 GO:0042168 heme metabolic process(GO:0042168)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.7 GO:0016055 Wnt signaling pathway(GO:0016055)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0035456 response to interferon-beta(GO:0035456)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.5 2.1 GO:1990032 parallel fiber(GO:1990032)
0.4 1.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.3 1.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.9 GO:0097447 dendritic tree(GO:0097447)
0.2 1.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 2.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 2.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 0.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 3.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.3 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 7.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.9 GO:0071437 invadopodium(GO:0071437)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 5.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 9.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 8.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.0 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.9 6.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.8 2.3 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.3 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 2.1 GO:0034056 estrogen response element binding(GO:0034056)
0.3 2.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 0.9 GO:0032052 bile acid binding(GO:0032052)
0.3 0.8 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 0.7 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 0.7 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 1.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 3.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 1.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 2.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 3.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 2.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.4 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.6 GO:0031489 myosin V binding(GO:0031489)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 9.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein light chain binding(GO:0045503)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.9 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0005496 steroid binding(GO:0005496)
0.0 0.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 9.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.6 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 2.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 2.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 2.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.3 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 2.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.2 1.4 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 2.9 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 3.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.9 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.9 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 7.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 2.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 2.7 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes