Motif ID: Pou4f3

Z-value: 0.327


Transcription factors associated with Pou4f3:

Gene SymbolEntrez IDGene Name
Pou4f3 ENSMUSG00000024497.3 Pou4f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f3mm10_v2_chr18_+_42394539_42394575-0.134.2e-01Click!


Activity profile for motif Pou4f3.

activity profile for motif Pou4f3


Sorted Z-values histogram for motif Pou4f3

Sorted Z-values for motif Pou4f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_114675431 1.161 ENSMUST00000045779.5
 Ttyh2
tweety homolog 2 (Drosophila)
chr18_+_11633276 1.105 ENSMUST00000115861.2
 Rbbp8
retinoblastoma binding protein 8
chr7_-_101837776 1.061 ENSMUST00000165052.1
 Inppl1
inositol polyphosphate phosphatase-like 1
chr10_+_37139558 1.005 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chrX_+_9885622 0.971 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5

chr1_+_194619815 0.747 ENSMUST00000027952.5
 Plxna2
plexin A2
chr17_-_48432723 0.697 ENSMUST00000046549.3
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr5_+_92809372 0.542 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr14_-_75754475 0.516 ENSMUST00000049168.7
 Cog3
component of oligomeric golgi complex 3
chr2_+_69670100 0.516 ENSMUST00000100050.3
 Klhl41
kelch-like 41
chrX_+_71816758 0.486 ENSMUST00000114576.2
ENSMUST00000114575.3
 Vma21

VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)

chr4_-_119190005 0.472 ENSMUST00000138395.1
ENSMUST00000156746.1
 Ermap

erythroblast membrane-associated protein

chr4_+_101986626 0.469 ENSMUST00000106914.1
 Gm12789
predicted gene 12789
chr17_+_6978860 0.464 ENSMUST00000089119.5
ENSMUST00000179728.1
 Rnaset2b

ribonuclease T2B

chr2_+_3424123 0.445 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
 Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr5_-_69590783 0.442 ENSMUST00000173927.1
 Gnpda2
glucosamine-6-phosphate deaminase 2
chr13_-_56296551 0.424 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr5_+_13398688 0.391 ENSMUST00000125629.1
 Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_+_115384951 0.375 ENSMUST00000036044.8
 Zfc3h1
zinc finger, C3H1-type containing
chr17_-_50094277 0.356 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr7_-_99980431 0.332 ENSMUST00000080817.4
 Rnf169
ring finger protein 169
chr1_+_109983737 0.322 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chr9_+_110132015 0.318 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
 Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr3_+_32436151 0.297 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr4_-_58499398 0.296 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr17_-_33033367 0.271 ENSMUST00000087654.4
 Zfp763
zinc finger protein 763
chr7_+_35802593 0.252 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr12_-_82496537 0.245 ENSMUST00000179295.1
 Gm5435
predicted gene 5435
chr10_-_76110956 0.245 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr7_-_46672537 0.211 ENSMUST00000049298.7
 Tph1
tryptophan hydroxylase 1
chr2_-_73580288 0.174 ENSMUST00000028515.3
 Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr8_-_83458386 0.164 ENSMUST00000081506.3
 Scoc
short coiled-coil protein
chr2_-_160619971 0.160 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chr9_+_123366921 0.150 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr2_-_92024502 0.147 ENSMUST00000028663.4
 Creb3l1
cAMP responsive element binding protein 3-like 1
chr12_+_72536342 0.144 ENSMUST00000044352.6
 Pcnxl4
pecanex-like 4 (Drosophila)
chr13_+_60601921 0.127 ENSMUST00000077453.5
 Dapk1
death associated protein kinase 1
chr17_+_21691860 0.125 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr13_-_58354862 0.100 ENSMUST00000043605.5
 Kif27
kinesin family member 27
chr10_-_63927434 0.091 ENSMUST00000079279.3
 Gm10118
predicted gene 10118
chr1_+_45795485 0.087 ENSMUST00000147308.1
 Wdr75
WD repeat domain 75
chr7_-_38019505 0.052 ENSMUST00000085513.4
 Uri1
URI1, prefoldin-like chaperone
chr9_+_110052016 0.029 ENSMUST00000164930.1
ENSMUST00000163979.1
 Map4

microtubule-associated protein 4

chr9_-_15301555 0.015 ENSMUST00000034414.8
 4931406C07Rik
RIKEN cDNA 4931406C07 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 1.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 1.2 GO:0006821 chloride transport(GO:0006821)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0005402 cation:sugar symporter activity(GO:0005402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.5 PID_ATM_PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination