Motif ID: Prdm14

Z-value: 0.327


Transcription factors associated with Prdm14:

Gene SymbolEntrez IDGene Name
Prdm14 ENSMUSG00000042414.7 Prdm14



Activity profile for motif Prdm14.

activity profile for motif Prdm14


Sorted Z-values histogram for motif Prdm14

Sorted Z-values for motif Prdm14



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm14

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_74297474 1.669 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr16_+_43235856 1.314 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr6_+_72355425 1.015 ENSMUST00000069695.2
ENSMUST00000132243.1
 Tmem150a

transmembrane protein 150A

chr11_-_89302545 0.948 ENSMUST00000061728.3
 Nog
noggin
chr9_+_94669876 0.911 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr10_-_128744014 0.830 ENSMUST00000026414.7
 Dgka
diacylglycerol kinase, alpha
chrX_+_99042581 0.754 ENSMUST00000036606.7
 Stard8
START domain containing 8
chr15_+_18818895 0.657 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr17_+_33555719 0.650 ENSMUST00000087605.5
ENSMUST00000174695.1
 Myo1f

myosin IF

chr8_+_46492789 0.629 ENSMUST00000110371.1
 Acsl1
acyl-CoA synthetase long-chain family member 1
chr4_+_119814495 0.614 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr18_+_37307445 0.450 ENSMUST00000056712.2
 Pcdhb4
protocadherin beta 4
chr4_-_88438900 0.367 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr15_+_99601372 0.363 ENSMUST00000023754.5
 Aqp6
aquaporin 6
chr15_-_76307231 0.309 ENSMUST00000023222.6
ENSMUST00000164189.1
 Oplah

5-oxoprolinase (ATP-hydrolysing)

chr2_-_144011202 0.301 ENSMUST00000016072.5
ENSMUST00000037875.5
 Rrbp1

ribosome binding protein 1

chr1_-_64121389 0.292 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr15_-_76307101 0.255 ENSMUST00000171340.1
 Oplah
5-oxoprolinase (ATP-hydrolysing)
chr18_-_15063560 0.252 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr19_-_6067785 0.244 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
 Tm7sf2






transmembrane 7 superfamily member 2






chr1_-_64121456 0.229 ENSMUST00000142009.1
ENSMUST00000114086.1
 Klf7

Kruppel-like factor 7 (ubiquitous)

chr3_-_109027600 0.217 ENSMUST00000171143.1
 Fam102b
family with sequence similarity 102, member B
chr18_-_70530138 0.203 ENSMUST00000161542.1
ENSMUST00000159389.1
 Poli

polymerase (DNA directed), iota

chr11_+_78324200 0.165 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr15_-_50890396 0.151 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr13_+_74639866 0.142 ENSMUST00000169114.1
 Erap1
endoplasmic reticulum aminopeptidase 1
chr18_-_70530313 0.128 ENSMUST00000043286.8
 Poli
polymerase (DNA directed), iota
chr7_+_114745685 0.100 ENSMUST00000136645.1
ENSMUST00000169913.1
 Insc

inscuteable homolog (Drosophila)

chr3_-_90213577 0.100 ENSMUST00000170122.2
 Rps27
ribosomal protein S27
chr1_+_88103229 0.091 ENSMUST00000113135.3
ENSMUST00000113138.1
 Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr1_+_88134786 0.089 ENSMUST00000113134.1
ENSMUST00000140092.1
 Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr12_-_69893162 0.063 ENSMUST00000049239.7
ENSMUST00000110570.1
 Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr7_+_27810813 0.056 ENSMUST00000080175.6
 Zfp626
zinc finger protein 626
chrX_+_74270812 0.050 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
 Rpl10



ribosomal protein L10



chr4_-_133672601 0.039 ENSMUST00000062118.4
ENSMUST00000067902.6
 Pigv

phosphatidylinositol glycan anchor biosynthesis, class V

chr17_+_26781060 0.038 ENSMUST00000015725.8
ENSMUST00000135824.1
ENSMUST00000137989.1
 Bnip1


BCL2/adenovirus E1B interacting protein 1


chr6_+_83109071 0.030 ENSMUST00000113938.3
 Mrpl53
mitochondrial ribosomal protein L53
chr7_+_18987518 0.006 ENSMUST00000063563.7
 Nanos2
nanos homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:0043312 neutrophil degranulation(GO:0043312)
0.1 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.6 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0019955 cytokine binding(GO:0019955)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis