Motif ID: Prdm4

Z-value: 0.456


Transcription factors associated with Prdm4:

Gene SymbolEntrez IDGene Name
Prdm4 ENSMUSG00000035529.9 Prdm4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prdm4mm10_v2_chr10_-_85916902_85917006-0.124.7e-01Click!


Activity profile for motif Prdm4.

activity profile for motif Prdm4


Sorted Z-values histogram for motif Prdm4

Sorted Z-values for motif Prdm4



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_102604370 5.640 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr1_+_74391479 3.693 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr10_+_126978690 3.165 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_-_4758216 2.670 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chr10_+_26822560 1.123 ENSMUST00000135866.1
Arhgap18
Rho GTPase activating protein 18
chr17_+_24473884 0.656 ENSMUST00000054946.3
ENSMUST00000164508.1
Bricd5

BRICHOS domain containing 5

chr19_-_4163285 0.639 ENSMUST00000118483.1
ENSMUST00000025749.7
Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

chr5_-_142817654 0.547 ENSMUST00000151477.1
Tnrc18
trinucleotide repeat containing 18
chr5_-_142817387 0.351 ENSMUST00000036253.6
Tnrc18
trinucleotide repeat containing 18
chr9_+_17030045 0.328 ENSMUST00000164523.2
Gm5611
predicted gene 5611
chr5_-_144965793 0.319 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr11_-_69369377 0.309 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr7_-_30743681 0.163 ENSMUST00000182634.1
Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr8_+_27042555 0.003 ENSMUST00000033875.8
ENSMUST00000098851.4
Prosc

proline synthetase co-transcribed


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.3 GO:0060022 hard palate development(GO:0060022)
0.1 6.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.3 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 8.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 8.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 6.9 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)