Motif ID: Rbpj

Z-value: 0.927


Transcription factors associated with Rbpj:

Gene SymbolEntrez IDGene Name
Rbpj ENSMUSG00000039191.6 Rbpj

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rbpjmm10_v2_chr5_+_53590453_535905740.508.9e-04Click!


Activity profile for motif Rbpj.

activity profile for motif Rbpj


Sorted Z-values histogram for motif Rbpj

Sorted Z-values for motif Rbpj



Network of associatons between targets according to the STRING database.



First level regulatory network of Rbpj

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_11007635 5.195 ENSMUST00000054776.3
Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr15_-_86033777 4.173 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_+_105668888 3.894 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr4_+_107830958 3.750 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr2_+_105668935 3.570 ENSMUST00000142772.1
Pax6
paired box gene 6
chr10_-_30842765 3.027 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr9_+_123478693 2.992 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr7_+_126781483 2.768 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr11_+_101627942 2.614 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chrX_+_139684980 2.527 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr7_-_44670820 2.359 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr3_-_89270489 2.083 ENSMUST00000107460.1
ENSMUST00000029565.4
ENSMUST00000130230.1
Slc50a1


solute carrier family 50 (sugar transporter), member 1


chr2_+_59612034 2.002 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr7_+_45216671 1.897 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr4_+_8690399 1.897 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr2_+_133552159 1.890 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr11_-_102579461 1.847 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr7_+_16842896 1.779 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr7_+_122159422 1.639 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chr16_+_44943737 1.612 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr7_+_44748413 1.514 ENSMUST00000002275.8
Vrk3
vaccinia related kinase 3
chr14_-_56571830 1.491 ENSMUST00000065302.7
Cenpj
centromere protein J
chr7_+_44748584 1.428 ENSMUST00000171821.1
Vrk3
vaccinia related kinase 3
chr7_+_44748640 1.402 ENSMUST00000165957.1
ENSMUST00000144515.2
Vrk3

vaccinia related kinase 3

chr11_-_62457289 1.346 ENSMUST00000069456.4
ENSMUST00000018645.6
Ncor1

nuclear receptor co-repressor 1

chr11_+_78324200 1.329 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr1_+_74153981 1.298 ENSMUST00000027372.7
ENSMUST00000106899.2
Cxcr2

chemokine (C-X-C motif) receptor 2

chr7_+_45639964 1.277 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr11_-_50887443 1.221 ENSMUST00000050595.6
ENSMUST00000163301.1
ENSMUST00000109131.1
ENSMUST00000125749.1
Zfp454



zinc finger protein 454



chr3_+_7612702 1.207 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr2_+_92184106 1.195 ENSMUST00000111294.1
ENSMUST00000111293.2
ENSMUST00000162146.1
ENSMUST00000111292.1
ENSMUST00000162497.1
Phf21a




PHD finger protein 21A




chrX_+_42149288 1.185 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr15_-_75894474 1.182 ENSMUST00000023237.6
Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr15_+_83563571 1.135 ENSMUST00000047419.6
Tspo
translocator protein
chr2_+_164403194 1.106 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr4_+_156203292 1.081 ENSMUST00000105140.2
AW011738
expressed sequence AW011738
chr7_-_105752193 1.078 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr1_+_97770158 1.073 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chr13_-_67360509 1.072 ENSMUST00000081582.6
ENSMUST00000185002.1
Zfp953
ZFP953
zinc finger protein 953
Protein Zfp953
chr9_-_26806384 1.058 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
Glb1l2


galactosidase, beta 1-like 2


chr1_-_191575534 1.021 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr6_+_29694204 1.020 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr6_+_21949571 0.998 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr9_-_55512156 0.989 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chrX_+_58030622 0.975 ENSMUST00000088627.4
Zic3
zinc finger protein of the cerebellum 3
chr12_-_4477138 0.921 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr11_-_62457772 0.914 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr2_-_26140468 0.899 ENSMUST00000133808.1
C330006A16Rik
RIKEN cDNA C330006A16 gene
chr4_-_147848358 0.881 ENSMUST00000105718.1
ENSMUST00000135798.1
Zfp933

zinc finger protein 933

chr5_-_88675613 0.871 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr18_+_34625009 0.865 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr15_-_81858317 0.863 ENSMUST00000050467.7
Tob2
transducer of ERBB2, 2
chr9_+_35559460 0.858 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr1_-_150393024 0.850 ENSMUST00000097546.2
ENSMUST00000111913.2
BC003331

cDNA sequence BC003331

chr12_+_31265279 0.832 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr6_+_48593883 0.813 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr12_+_31265234 0.795 ENSMUST00000169088.1
Lamb1
laminin B1
chr1_+_87326997 0.782 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr11_-_69197809 0.779 ENSMUST00000094078.3
ENSMUST00000021262.3
Alox8

arachidonate 8-lipoxygenase

chr3_-_103809278 0.774 ENSMUST00000063502.6
ENSMUST00000106832.1
ENSMUST00000106834.1
ENSMUST00000029435.8
Dclre1b



DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)



chr13_-_67609667 0.769 ENSMUST00000012873.8
AA987161
expressed sequence AA987161
chr7_+_30095150 0.765 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr5_-_75978447 0.756 ENSMUST00000113516.1
Kdr
kinase insert domain protein receptor
chr1_+_150393250 0.732 ENSMUST00000119161.2
Tpr
translocated promoter region
chr5_+_3543812 0.728 ENSMUST00000115527.3
Fam133b
family with sequence similarity 133, member B
chr15_-_55072139 0.718 ENSMUST00000041733.7
Taf2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_+_154548888 0.710 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr1_+_87327008 0.707 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr1_+_87327044 0.699 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr2_+_164746028 0.697 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr13_-_67609617 0.696 ENSMUST00000138725.1
AA987161
expressed sequence AA987161
chr7_-_24208093 0.691 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr10_+_116301374 0.686 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr19_+_7297658 0.680 ENSMUST00000170286.1
Gm17227
predicted gene 17227
chr3_-_131344892 0.670 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2

sphingomyelin synthase 2

chr2_-_69586021 0.662 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr3_+_146220955 0.656 ENSMUST00000039164.2
Lpar3
lysophosphatidic acid receptor 3
chrX_+_99136119 0.638 ENSMUST00000052839.6
Efnb1
ephrin B1
chr2_+_119547697 0.617 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chr13_-_67451585 0.610 ENSMUST00000057241.8
ENSMUST00000075255.5
Zfp874a

zinc finger protein 874a

chr13_-_67484225 0.602 ENSMUST00000019572.7
Zfp874b
zinc finger protein 874b
chr5_-_88675190 0.596 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr13_+_67813740 0.593 ENSMUST00000181391.1
ENSMUST00000012725.7
Zfp273

zinc finger protein 273

chr6_-_97205549 0.581 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3

ubiquitin-like modifier activating enzyme 3

chr6_-_37299950 0.578 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr10_-_62726086 0.576 ENSMUST00000133371.1
Stox1
storkhead box 1
chr7_+_5020561 0.573 ENSMUST00000085427.3
Zfp865
zinc finger protein 865
chrX_-_160138375 0.573 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr5_+_138171997 0.573 ENSMUST00000019662.4
ENSMUST00000151318.1
Ap4m1

adaptor-related protein complex AP-4, mu 1

chr12_+_33315393 0.543 ENSMUST00000154742.1
Atxn7l1
ataxin 7-like 1
chr12_+_82170016 0.543 ENSMUST00000166429.1
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr8_-_111743799 0.537 ENSMUST00000166232.2
Bcar1
breast cancer anti-estrogen resistance 1
chr5_+_138187485 0.526 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr18_+_34624621 0.520 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr2_+_164745979 0.510 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr8_-_69974367 0.508 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr7_+_29983948 0.473 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr2_-_54085542 0.456 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr15_+_6708372 0.454 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr9_-_103222063 0.446 ENSMUST00000170904.1
Trf
transferrin
chr7_+_29768552 0.445 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr1_+_20951666 0.440 ENSMUST00000038447.4
Efhc1
EF-hand domain (C-terminal) containing 1
chr7_-_29853611 0.426 ENSMUST00000085792.4
ENSMUST00000108223.1
Zfp940

zinc finger protein 940

chr5_+_148959263 0.425 ENSMUST00000135240.1
Gm15409
predicted gene 15409
chr13_-_67306412 0.424 ENSMUST00000049705.7
Zfp457
zinc finger protein 457
chr19_-_6992478 0.416 ENSMUST00000025915.5
Dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr16_-_75766758 0.416 ENSMUST00000114244.1
ENSMUST00000046283.8
Hspa13

heat shock protein 70 family, member 13

chr13_+_67128219 0.408 ENSMUST00000052716.7
Zfp759
zinc finger protein 759
chr2_-_120609500 0.391 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr7_+_79273201 0.390 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr9_-_114640175 0.388 ENSMUST00000070117.6
Cnot10
CCR4-NOT transcription complex, subunit 10
chr6_+_117841258 0.375 ENSMUST00000136889.1
ENSMUST00000134526.1
ENSMUST00000112860.1
ENSMUST00000112858.1
Zfp637



zinc finger protein 637



chr1_+_191575721 0.374 ENSMUST00000045450.5
Ints7
integrator complex subunit 7
chr2_+_23068168 0.373 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chr5_+_33658550 0.371 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr9_+_64811313 0.370 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr18_-_37935403 0.355 ENSMUST00000080033.6
ENSMUST00000115631.1
Diap1

diaphanous homolog 1 (Drosophila)

chr10_-_93889609 0.354 ENSMUST00000180375.1
Metap2
methionine aminopeptidase 2
chr18_-_37935429 0.347 ENSMUST00000115634.1
Diap1
diaphanous homolog 1 (Drosophila)
chr18_-_37935378 0.347 ENSMUST00000025337.7
Diap1
diaphanous homolog 1 (Drosophila)
chr7_+_127777376 0.344 ENSMUST00000126761.1
ENSMUST00000047157.6
Setd1a

SET domain containing 1A

chr2_-_120609283 0.341 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr2_-_120609319 0.334 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr17_+_34205100 0.333 ENSMUST00000131105.1
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_106821874 0.333 ENSMUST00000159645.1
Vprbp
Vpr (HIV-1) binding protein
chr7_+_5015466 0.326 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chr2_+_26581050 0.325 ENSMUST00000166920.2
Egfl7
EGF-like domain 7
chr11_-_50916136 0.311 ENSMUST00000116378.1
ENSMUST00000109128.1
Zfp2

zinc finger protein 2

chr2_+_120609383 0.278 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr10_+_29313227 0.276 ENSMUST00000161605.1
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr12_-_80260091 0.275 ENSMUST00000167327.1
Actn1
actinin, alpha 1
chr5_-_138172383 0.273 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_+_12395362 0.264 ENSMUST00000059270.8
Heatr1
HEAT repeat containing 1
chr2_+_120404757 0.263 ENSMUST00000135074.1
Ganc
glucosidase, alpha; neutral C
chr7_+_5020376 0.251 ENSMUST00000076251.4
Zfp865
zinc finger protein 865
chr13_+_67779754 0.242 ENSMUST00000164936.2
ENSMUST00000181319.1
Zfp493

zinc finger protein 493

chr6_+_117841174 0.238 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
Zfp637




zinc finger protein 637




chr13_-_67332525 0.234 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr7_-_127890918 0.224 ENSMUST00000121394.1
Prss53
protease, serine, 53
chr5_+_130257029 0.208 ENSMUST00000100662.3
ENSMUST00000040213.6
Tyw1

tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)

chrX_+_100494291 0.204 ENSMUST00000033570.5
Igbp1
immunoglobulin (CD79A) binding protein 1
chr2_-_119547627 0.202 ENSMUST00000060009.2
Exd1
exonuclease 3'-5' domain containing 1
chr2_+_37776229 0.198 ENSMUST00000050372.7
Crb2
crumbs homolog 2 (Drosophila)
chr16_+_22009471 0.193 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr4_-_126202757 0.170 ENSMUST00000080919.5
Thrap3
thyroid hormone receptor associated protein 3
chr3_+_103809520 0.165 ENSMUST00000076599.1
ENSMUST00000106824.1
ENSMUST00000106823.1
ENSMUST00000047285.2
Ap4b1



adaptor-related protein complex AP-4, beta 1



chr14_-_66124482 0.163 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr5_-_106696819 0.163 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr5_-_106696530 0.163 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr8_+_110721462 0.154 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr11_-_103344651 0.147 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr13_-_67269068 0.141 ENSMUST00000045969.7
Zfp458
zinc finger protein 458
chr12_-_88286055 0.137 ENSMUST00000179741.1
Gm7104
predicted gene 7104
chr11_+_109485606 0.131 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr14_-_78536854 0.125 ENSMUST00000022593.5
Akap11
A kinase (PRKA) anchor protein 11
chr10_+_29313500 0.111 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr7_+_29816061 0.109 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr2_+_83644435 0.102 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr13_+_21478907 0.097 ENSMUST00000062609.5
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr3_+_61364507 0.095 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr10_+_40349265 0.093 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr6_-_118455475 0.083 ENSMUST00000161519.1
ENSMUST00000069292.7
Zfp248

zinc finger protein 248

chr12_-_36382181 0.083 ENSMUST00000171007.1
D630036H23Rik
RIKEN cDNA D630036H23 gene
chr19_-_41933276 0.074 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chrX_-_37085402 0.066 ENSMUST00000115231.3
Rpl39
ribosomal protein L39
chr11_+_54314960 0.058 ENSMUST00000064690.3
ENSMUST00000108899.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr4_+_116995306 0.056 ENSMUST00000050067.9
Hectd3
HECT domain containing 3
chr19_-_10577362 0.055 ENSMUST00000025568.2
Tmem138
transmembrane protein 138
chr14_-_78536762 0.052 ENSMUST00000123853.1
Akap11
A kinase (PRKA) anchor protein 11
chr18_+_37736897 0.029 ENSMUST00000091935.4
Pcdhga9
protocadherin gamma subfamily A, 9
chrX_+_7579666 0.029 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr4_-_126202583 0.027 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr12_-_14152038 0.022 ENSMUST00000020926.6
Fam84a
family with sequence similarity 84, member A
chr11_+_78178651 0.013 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr17_+_35121455 0.007 ENSMUST00000173380.1
ENSMUST00000173043.3
ENSMUST00000165306.2
Gpank1


G patch domain and ankyrin repeats 1


chr9_-_66795469 0.005 ENSMUST00000034934.8
Aph1b
anterior pharynx defective 1b homolog (C. elegans)
chr4_-_117914968 0.004 ENSMUST00000036156.5
Ipo13
importin 13
chrX_-_134600976 0.003 ENSMUST00000033621.6
Gla
galactosidase, alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.4 4.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.0 3.0 GO:0003195 tricuspid valve formation(GO:0003195)
0.9 1.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 1.9 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.6 2.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.4 3.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 3.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 1.6 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
0.4 1.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 2.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.3 1.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.3 0.9 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.3 1.5 GO:0061511 centriole elongation(GO:0061511)
0.3 2.5 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.2 0.7 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 4.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 1.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.2 0.8 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 1.5 GO:0015074 DNA integration(GO:0015074)
0.2 0.5 GO:1990859 cellular response to endothelin(GO:1990859)
0.2 1.0 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 2.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 0.5 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 1.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.5 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.6 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 0.3 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1 1.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 4.5 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.1 1.9 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.2 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.1 2.0 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 1.2 GO:0001967 suckling behavior(GO:0001967)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.6 GO:0046959 habituation(GO:0046959)
0.1 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 1.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.6 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.4 GO:0032570 response to progesterone(GO:0032570)
0.0 0.7 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) transcytosis(GO:0045056)
0.0 2.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.8 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.0 GO:0032829 tolerance induction to self antigen(GO:0002513) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.0 0.5 GO:0032880 regulation of protein localization(GO:0032880)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 1.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.4 1.6 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 2.4 GO:0097513 myosin II filament(GO:0097513)
0.3 5.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 3.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.3 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 2.2 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 0.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 2.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.7 GO:0005901 caveola(GO:0005901)
0.0 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 7.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 2.0 GO:0043679 axon terminus(GO:0043679)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0035939 microsatellite binding(GO:0035939)
0.9 3.7 GO:0038025 reelin receptor activity(GO:0038025)
0.5 7.5 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.3 2.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.3 1.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.9 GO:0019211 phosphatase activator activity(GO:0019211)
0.3 1.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.7 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.2 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 1.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 0.9 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:1990188 euchromatin binding(GO:1990188)
0.1 0.3 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 2.1 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.1 GO:0030594 neurotransmitter receptor activity(GO:0030594)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 4.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 3.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 3.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 7.7 PID_CDC42_PATHWAY CDC42 signaling events
0.1 4.2 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.9 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 3.7 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.2 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.6 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.4 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.7 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 1.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.5 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication