---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_74791516	21.086	ENSMUST00000006718.8	Wnt10a	wingless related MMTV integration site 10a
chr8_-_61902669	12.992	ENSMUST00000121785.1 ENSMUST00000034057.7	Palld	palladin, cytoskeletal associated protein
chr18_+_60803838	12.285	ENSMUST00000050487.8 ENSMUST00000097563.2 ENSMUST00000167610.1	Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr6_-_48840988	10.992	ENSMUST00000164733.1	Tmem176b	transmembrane protein 176B
chr6_-_48841098	10.985	ENSMUST00000101429.4	Tmem176b	transmembrane protein 176B
chr9_-_119093468	10.889	ENSMUST00000010804.2	Plcd1	phospholipase C, delta 1
chr6_-_48841373	10.633	ENSMUST00000166247.1	Tmem176b	transmembrane protein 176B
chr17_-_34287770	10.183	ENSMUST00000174751.1 ENSMUST00000040655.6	H2-Aa	histocompatibility 2, class II antigen A, alpha
chr6_+_48841476	9.359	ENSMUST00000101426.4	Tmem176a	transmembrane protein 176A
chr6_+_48841633	9.141	ENSMUST00000168406.1	Tmem176a	transmembrane protein 176A
chr17_-_56005566	8.409	ENSMUST00000043785.6	Stap2	signal transducing adaptor family member 2
chr17_-_35000848	8.079	ENSMUST00000166828.3	D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr5_+_92925400	8.064	ENSMUST00000172706.1	Shroom3	shroom family member 3
chr1_+_64532790	7.857	ENSMUST00000049932.5 ENSMUST00000087366.4 ENSMUST00000171164.1	Creb1	cAMP responsive element binding protein 1
chr1_+_185454803	7.588	ENSMUST00000061093.6	Slc30a10	solute carrier family 30, member 10
chr2_-_165234689	7.377	ENSMUST00000065438.6	Cdh22	cadherin 22
chr17_-_35702040	7.168	ENSMUST00000166980.2 ENSMUST00000145900.1	Ddr1	discoidin domain receptor family, member 1
chr2_-_151973387	7.052	ENSMUST00000109863.1	Fam110a	family with sequence similarity 110, member A
chr17_-_35701937	6.629	ENSMUST00000155628.1	Ddr1	discoidin domain receptor family, member 1
chr7_-_25788635	6.327	ENSMUST00000002677.4 ENSMUST00000085948.4	Axl	AXL receptor tyrosine kinase
chr10_-_19015347	6.254	ENSMUST00000019997.4	Tnfaip3	tumor necrosis factor, alpha-induced protein 3
chr8_+_70863127	6.193	ENSMUST00000050921.2	A230052G05Rik	RIKEN cDNA A230052G05 gene
chr17_-_35000746	6.123	ENSMUST00000163360.1	D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr2_-_151973840	6.080	ENSMUST00000109865.1 ENSMUST00000109864.1	Fam110a	family with sequence similarity 110, member A
chr4_-_135272798	5.934	ENSMUST00000037099.8	Clic4	chloride intracellular channel 4 (mitochondrial)
chr7_-_102250086	5.890	ENSMUST00000106923.1 ENSMUST00000098230.4	Rhog	ras homolog gene family, member G
chr6_+_4755327	5.875	ENSMUST00000176551.1	Peg10	paternally expressed 10
chr17_-_35702297	5.802	ENSMUST00000135078.1	Ddr1	discoidin domain receptor family, member 1
chr12_+_79029150	5.698	ENSMUST00000039928.5	Plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr11_+_101176041	5.633	ENSMUST00000103109.3	Cntnap1	contactin associated protein-like 1
chr7_+_75455534	5.474	ENSMUST00000147005.1 ENSMUST00000166315.1	Akap13	A kinase (PRKA) anchor protein 13
chr9_+_54764748	5.385	ENSMUST00000034830.8	Crabp1	cellular retinoic acid binding protein I
chr8_+_46739745	5.250	ENSMUST00000034041.7	Irf2	interferon regulatory factor 2
chr19_+_46304709	5.236	ENSMUST00000073116.5	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr3_-_116424007	4.893	ENSMUST00000090464.4	Cdc14a	CDC14 cell division cycle 14A
chr5_+_53590453	4.890	ENSMUST00000113865.1	Rbpj	recombination signal binding protein for immunoglobulin kappa J region
chr18_+_4994600	4.770	ENSMUST00000140448.1	Svil	supervillin
chr1_-_82291370	4.769	ENSMUST00000069799.2	Irs1	insulin receptor substrate 1
chr11_-_54962903	4.738	ENSMUST00000108885.1 ENSMUST00000102730.2 ENSMUST00000018482.6 ENSMUST00000108886.1 ENSMUST00000102731.1	Tnip1	TNFAIP3 interacting protein 1
chr4_+_80910646	4.688	ENSMUST00000055922.3	Lurap1l	leucine rich adaptor protein 1-like
chr4_-_42168603	4.629	ENSMUST00000098121.3	Gm13305	predicted gene 13305
chr4_-_91399984	4.615	ENSMUST00000102799.3	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_-_116423930	4.512	ENSMUST00000106491.2	Cdc14a	CDC14 cell division cycle 14A
chr2_-_181459364	4.494	ENSMUST00000155535.1 ENSMUST00000029106.6 ENSMUST00000087409.3	Zbtb46	zinc finger and BTB domain containing 46
chr1_+_171250416	4.367	ENSMUST00000111315.1 ENSMUST00000006570.5	Adamts4	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
chr5_+_53590215	4.351	ENSMUST00000037618.6	Rbpj	recombination signal binding protein for immunoglobulin kappa J region
chr3_-_65958236	4.326	ENSMUST00000029416.7	Ccnl1	cyclin L1
chr15_-_89170688	4.298	ENSMUST00000060808.9	Plxnb2	plexin B2
chr7_-_44815658	4.221	ENSMUST00000107893.1	Atf5	activating transcription factor 5
chr13_+_33964659	4.216	ENSMUST00000021843.5 ENSMUST00000058978.7	Nqo2	NAD(P)H dehydrogenase, quinone 2
chr3_-_101836223	4.168	ENSMUST00000061831.4	Mab21l3	mab-21-like 3 (C. elegans)
chr11_+_78301529	4.157	ENSMUST00000045026.3	Spag5	sperm associated antigen 5
chr5_-_106458440	4.096	ENSMUST00000086795.6	Barhl2	BarH-like 2 (Drosophila)
chr2_+_105682463	4.057	ENSMUST00000140173.1 ENSMUST00000135412.1 ENSMUST00000138365.1 ENSMUST00000145744.1	Pax6	paired box gene 6
chr6_+_134035691	4.017	ENSMUST00000081028.6 ENSMUST00000111963.1	Etv6	ets variant gene 6 (TEL oncogene)
chr9_-_72491939	3.940	ENSMUST00000185151.1 ENSMUST00000085358.5 ENSMUST00000184125.1 ENSMUST00000183574.1 ENSMUST00000184831.1	Tex9	testis expressed gene 9
chr17_+_43667389	3.925	ENSMUST00000170988.1	Cyp39a1	cytochrome P450, family 39, subfamily a, polypeptide 1
chr6_+_125096145	3.888	ENSMUST00000112390.1	Chd4	chromodomain helicase DNA binding protein 4
chr14_-_37098211	3.886	ENSMUST00000022337.9	Cdhr1	cadherin-related family member 1
chr3_-_135691512	3.846	ENSMUST00000029812.7	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr17_+_37193889	3.844	ENSMUST00000038844.6	Ubd	ubiquitin D
chr6_+_83135812	3.762	ENSMUST00000065512.4	Rtkn	rhotekin
chr11_+_94211431	3.759	ENSMUST00000041589.5	Tob1	transducer of ErbB-2.1
chr13_+_51846673	3.739	ENSMUST00000021903.2	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma
chr9_+_65265173	3.735	ENSMUST00000048762.1	Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr13_+_42052015	3.732	ENSMUST00000060148.5	Hivep1	human immunodeficiency virus type I enhancer binding protein 1
chr2_+_124089961	3.721	ENSMUST00000103241.1	Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr19_-_58454580	3.674	ENSMUST00000129100.1 ENSMUST00000123957.1	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1
chr19_-_58455161	3.672	ENSMUST00000135730.1 ENSMUST00000152507.1	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1
chr5_+_33658123	3.642	ENSMUST00000074849.6 ENSMUST00000079534.4	Tacc3	transforming, acidic coiled-coil containing protein 3
chr19_-_58454435	3.636	ENSMUST00000169850.1	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1
chr10_-_49788743	3.573	ENSMUST00000105483.1 ENSMUST00000105487.1	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)
chr8_+_90828820	3.515	ENSMUST00000109614.2 ENSMUST00000048665.6	Chd9	chromodomain helicase DNA binding protein 9
chrX_-_74246364	3.508	ENSMUST00000130007.1	Flna	filamin, alpha
chr19_-_40271506	3.507	ENSMUST00000068439.6	Pdlim1	PDZ and LIM domain 1 (elfin)
chr1_-_134079114	3.500	ENSMUST00000020692.6	Btg2	B cell translocation gene 2, anti-proliferative
chr19_+_46305682	3.489	ENSMUST00000111881.2	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr17_+_35424870	3.484	ENSMUST00000113879.3	H2-Q6	histocompatibility 2, Q region locus 6
chr2_-_118549668	3.450	ENSMUST00000090219.6	Bmf	BCL2 modifying factor
chrX_+_7657260	3.433	ENSMUST00000033485.7	Prickle3	prickle homolog 3 (Drosophila)
chr9_+_60794468	3.406	ENSMUST00000050183.6	Uaca	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_-_84194007	3.369	ENSMUST00000110294.1	Elmsan1	ELM2 and Myb/SANT-like domain containing 1
chr2_+_144556229	3.358	ENSMUST00000143573.1 ENSMUST00000028916.8 ENSMUST00000155258.1	Sec23b	SEC23B (S. cerevisiae)
chr2_-_26294550	3.334	ENSMUST00000057224.3	4932418E24Rik	RIKEN cDNA 4932418E24 gene
chr10_+_25359798	3.326	ENSMUST00000053748.8	Epb4.1l2	erythrocyte protein band 4.1-like 2
chr15_+_99717515	3.299	ENSMUST00000023760.6 ENSMUST00000162194.1	Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)
chr4_+_100776664	3.261	ENSMUST00000030257.8 ENSMUST00000097955.2	Cachd1	cache domain containing 1
chr9_-_14614949	3.227	ENSMUST00000013220.6 ENSMUST00000160770.1	Amotl1	angiomotin-like 1
chr7_+_45017953	3.224	ENSMUST00000044111.7	Rras	Harvey rat sarcoma oncogene, subgroup R
chr1_+_109983006	3.217	ENSMUST00000145188.1	Cdh7	cadherin 7, type 2
chr15_-_75747922	3.211	ENSMUST00000062002.4	Mafa	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr5_-_105139539	3.196	ENSMUST00000100961.4 ENSMUST00000031235.6 ENSMUST00000100962.3	Gbp9 Gbp8 Gbp4	guanylate-binding protein 9 guanylate-binding protein 8 guanylate binding protein 4
chr17_-_23745829	3.181	ENSMUST00000046525.8	Kremen2	kringle containing transmembrane protein 2
chr2_+_144556306	3.050	ENSMUST00000155876.1 ENSMUST00000149697.1	Sec23b	SEC23B (S. cerevisiae)
chr7_+_79500081	3.048	ENSMUST00000181511.2 ENSMUST00000182937.1	AI854517	expressed sequence AI854517
chr6_+_8948608	3.047	ENSMUST00000160300.1	Nxph1	neurexophilin 1
chr3_+_40800054	3.038	ENSMUST00000168287.1	Plk4	polo-like kinase 4
chr10_+_111506286	3.034	ENSMUST00000164773.1	Phlda1	pleckstrin homology-like domain, family A, member 1
chr10_-_127751707	3.033	ENSMUST00000079692.5	Gpr182	G protein-coupled receptor 182
chr5_+_92683625	3.030	ENSMUST00000168878.1	Shroom3	shroom family member 3
chr2_+_156840077	3.030	ENSMUST00000081335.6 ENSMUST00000073352.3	Tgif2	TGFB-induced factor homeobox 2
chr12_+_52699297	3.000	ENSMUST00000095737.3	Akap6	A kinase (PRKA) anchor protein 6
chr9_+_91368970	2.990	ENSMUST00000172646.1	Zic4	zinc finger protein of the cerebellum 4
chr3_+_40800013	2.931	ENSMUST00000026858.5 ENSMUST00000170825.1	Plk4	polo-like kinase 4
chr7_+_25681158	2.885	ENSMUST00000108403.3	B9d2	B9 protein domain 2
chr4_+_129820198	2.855	ENSMUST00000030578.7	Ptp4a2	protein tyrosine phosphatase 4a2
chr7_-_142899985	2.797	ENSMUST00000000219.3	Th	tyrosine hydroxylase
chr5_-_137116177	2.773	ENSMUST00000054384.5 ENSMUST00000152207.1	Trim56	tripartite motif-containing 56
chr3_+_7612702	2.741	ENSMUST00000181286.1	Gm16685	predicted gene, 16685
chr6_+_34354119	2.728	ENSMUST00000038406.6	Akr1b8	aldo-keto reductase family 1, member B8
chr9_-_22389113	2.671	ENSMUST00000040912.7	Anln	anillin, actin binding protein
chr5_+_30105161	2.667	ENSMUST00000058045.4	Gareml	GRB2 associated, regulator of MAPK1-like
chr14_+_120275669	2.623	ENSMUST00000088419.6 ENSMUST00000167459.1	Mbnl2	muscleblind-like 2
chr4_-_24430838	2.608	ENSMUST00000183964.1	RP23-35K5.2	RP23-35K5.2
chr14_+_52016849	2.601	ENSMUST00000100638.2	Tmem253	transmembrane protein 253
chr11_-_69580230	2.593	ENSMUST00000132548.1	Wrap53	WD repeat containing, antisense to Trp53
chr19_+_45015198	2.593	ENSMUST00000179108.1	Lzts2	leucine zipper, putative tumor suppressor 2
chr12_-_91746020	2.578	ENSMUST00000166967.1	Ston2	stonin 2
chr19_+_45015168	2.573	ENSMUST00000039016.6	Lzts2	leucine zipper, putative tumor suppressor 2
chr4_+_11704439	2.552	ENSMUST00000108304.2	Gem	GTP binding protein (gene overexpressed in skeletal muscle)
chr1_+_109982710	2.531	ENSMUST00000112701.1	Cdh7	cadherin 7, type 2
chr2_-_37422869	2.519	ENSMUST00000112936.1 ENSMUST00000112934.1	Rc3h2	ring finger and CCCH-type zinc finger domains 2
chrX_-_74246534	2.517	ENSMUST00000101454.2 ENSMUST00000033699.6	Flna	filamin, alpha
chr13_+_44730726	2.516	ENSMUST00000173704.1 ENSMUST00000044608.7 ENSMUST00000173367.1	Jarid2	jumonji, AT rich interactive domain 2
chr14_+_55540266	2.514	ENSMUST00000048781.3	Pck2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr9_-_102626095	2.478	ENSMUST00000093791.3	Cep63	centrosomal protein 63
chrX_+_7762652	2.470	ENSMUST00000077680.3 ENSMUST00000079542.6 ENSMUST00000115679.1 ENSMUST00000137467.1	Tfe3	transcription factor E3
chr9_+_91368811	2.458	ENSMUST00000173054.1	Zic4	zinc finger protein of the cerebellum 4
chr16_+_32914094	2.439	ENSMUST00000023491.6 ENSMUST00000170899.1 ENSMUST00000171118.1 ENSMUST00000170201.1 ENSMUST00000165616.1 ENSMUST00000135193.2	Lrch3	leucine-rich repeats and calponin homology (CH) domain containing 3
chr10_-_120899067	2.414	ENSMUST00000092143.5	Msrb3	methionine sulfoxide reductase B3
chr10_+_7725997	2.399	ENSMUST00000019929.6 ENSMUST00000165806.1	Katna1	katanin p60 (ATPase-containing) subunit A1
chr11_-_115535804	2.378	ENSMUST00000117589.1 ENSMUST00000121185.1	Sumo2	SMT3 suppressor of mif two 3 homolog 2 (yeast)
chr19_+_5740885	2.377	ENSMUST00000081496.5	Ltbp3	latent transforming growth factor beta binding protein 3
chr3_+_86224665	2.376	ENSMUST00000107635.1	Lrba	LPS-responsive beige-like anchor
chr17_-_31277327	2.370	ENSMUST00000024832.7	Rsph1	radial spoke head 1 homolog (Chlamydomonas)
chr10_-_127522428	2.353	ENSMUST00000026470.4	Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_13573927	2.349	ENSMUST00000141365.1 ENSMUST00000028062.2	Vim	vimentin
chr17_-_70851189	2.349	ENSMUST00000059775.8	Tgif1	TGFB-induced factor homeobox 1
chr12_+_111166485	2.310	ENSMUST00000139162.1	Traf3	TNF receptor-associated factor 3
chr11_-_115813621	2.305	ENSMUST00000041684.4 ENSMUST00000156812.1	Caskin2	CASK-interacting protein 2
chr6_+_42349826	2.297	ENSMUST00000070635.6	Zyx	zyxin
chr6_+_42350000	2.279	ENSMUST00000164375.1	Zyx	zyxin
chr4_+_128755364	2.260	ENSMUST00000106077.1	A3galt2	alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr11_-_70656467	2.247	ENSMUST00000131642.1	Gm12319	predicted gene 12319
chr5_-_30105359	2.233	ENSMUST00000127749.3	3110082J24Rik	RIKEN cDNA 3110082J24 gene
chr8_-_25201349	2.231	ENSMUST00000084512.4 ENSMUST00000084030.4	Tacc1	transforming, acidic coiled-coil containing protein 1
chr9_-_75409951	2.226	ENSMUST00000049355.10	Mapk6	mitogen-activated protein kinase 6
chr3_+_89229046	2.169	ENSMUST00000041142.3	Muc1	mucin 1, transmembrane
chr5_-_105293699	2.159	ENSMUST00000050011.8	Gbp6	guanylate binding protein 6
chr14_-_70642268	2.094	ENSMUST00000022697.5	Fgf17	fibroblast growth factor 17
chr1_+_82316452	2.075	ENSMUST00000027322.7	Rhbdd1	rhomboid domain containing 1
chr10_-_7780866	2.067	ENSMUST00000124838.1 ENSMUST00000039763.7	Ginm1	glycoprotein integral membrane 1
chr17_+_35821675	2.056	ENSMUST00000003635.6	Ier3	immediate early response 3
chr5_+_114568016	2.050	ENSMUST00000043650.7	Fam222a	family with sequence similarity 222, member A
chr10_+_128303322	2.016	ENSMUST00000005825.6	Pan2	PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr7_-_19629355	2.013	ENSMUST00000049912.8 ENSMUST00000094762.3 ENSMUST00000098754.4	Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B
chr6_+_120773633	1.986	ENSMUST00000112682.2	Slc25a18	solute carrier family 25 (mitochondrial carrier), member 18
chr3_+_142496924	1.980	ENSMUST00000090127.2	Gbp5	guanylate binding protein 5
chr11_+_114727384	1.969	ENSMUST00000069325.7	Dnaic2	dynein, axonemal, intermediate chain 2
chr2_-_121235689	1.935	ENSMUST00000142400.1	Trp53bp1	transformation related protein 53 binding protein 1
chr1_-_136230289	1.927	ENSMUST00000150163.1 ENSMUST00000144464.1	5730559C18Rik	RIKEN cDNA 5730559C18 gene
chr11_+_69580359	1.896	ENSMUST00000005371.5 ENSMUST00000108658.3 ENSMUST00000171247.1	Trp53	transformation related protein 53
chr7_-_127014585	1.895	ENSMUST00000165096.2	Mvp	major vault protein
chr6_-_5256226	1.866	ENSMUST00000125686.1 ENSMUST00000031773.2	Pon3	paraoxonase 3
chr11_+_53519725	1.844	ENSMUST00000108987.1 ENSMUST00000121334.1 ENSMUST00000117061.1	Sept8	septin 8
chr10_-_49783259	1.826	ENSMUST00000105484.3 ENSMUST00000105486.1 ENSMUST00000079751.2 ENSMUST00000105485.1	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)
chr5_+_136967859	1.823	ENSMUST00000001790.5	Cldn15	claudin 15
chr12_+_85288591	1.822	ENSMUST00000059341.4	Zc2hc1c	zinc finger, C2HC-type containing 1C
chr9_+_64117147	1.818	ENSMUST00000034969.7	Lctl	lactase-like
chr17_+_31057686	1.813	ENSMUST00000024829.6	Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1
chr13_+_113035111	1.804	ENSMUST00000180543.1 ENSMUST00000181568.1 ENSMUST00000109244.2 ENSMUST00000181117.1 ENSMUST00000181741.1	Cdc20b	cell division cycle 20B
chr11_+_69580392	1.800	ENSMUST00000108657.3	Trp53	transformation related protein 53
chr11_+_53519871	1.784	ENSMUST00000120878.2	Sept8	septin 8
chr17_+_45555693	1.773	ENSMUST00000024742.7	Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr10_-_127288851	1.766	ENSMUST00000156208.1 ENSMUST00000026476.6	Mbd6	methyl-CpG binding domain protein 6
chr12_+_104214538	1.757	ENSMUST00000121337.1 ENSMUST00000167049.1 ENSMUST00000101080.1	Serpina3f	serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr11_+_101316917	1.748	ENSMUST00000151385.1	Psme3	proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr11_+_53519920	1.739	ENSMUST00000147912.1	Sept8	septin 8
chr10_+_58394381	1.723	ENSMUST00000105468.1	Lims1	LIM and senescent cell antigen-like domains 1
chr11_-_54956047	1.723	ENSMUST00000155316.1 ENSMUST00000108889.3 ENSMUST00000126703.1	Tnip1	TNFAIP3 interacting protein 1
chr11_+_101448403	1.716	ENSMUST00000010502.6	Ifi35	interferon-induced protein 35
chr5_+_30013141	1.714	ENSMUST00000026845.7	Il6	interleukin 6
chr12_+_79130777	1.709	ENSMUST00000021550.6	Arg2	arginase type II
chr5_-_17835857	1.690	ENSMUST00000082367.6	Cd36	CD36 antigen
chr10_+_128790903	1.677	ENSMUST00000026411.6	Mmp19	matrix metallopeptidase 19
chr19_-_24861828	1.677	ENSMUST00000047666.4	Pgm5	phosphoglucomutase 5
chr2_+_61578549	1.653	ENSMUST00000112502.1 ENSMUST00000078074.2	Tank	TRAF family member-associated Nf-kappa B activator
chr5_-_92328068	1.639	ENSMUST00000113093.3	Cxcl9	chemokine (C-X-C motif) ligand 9
chr14_+_55884960	1.635	ENSMUST00000022831.3	Khnyn	KH and NYN domain containing
chr9_-_103480328	1.629	ENSMUST00000124310.2	Bfsp2	beaded filament structural protein 2, phakinin
chr3_+_89421619	1.628	ENSMUST00000094378.3 ENSMUST00000137793.1	Shc1	src homology 2 domain-containing transforming protein C1
chr14_-_48662740	1.621	ENSMUST00000122009.1	Otx2	orthodenticle homolog 2 (Drosophila)
chr6_+_113237843	1.620	ENSMUST00000113146.2	Mtmr14	myotubularin related protein 14
chr16_-_33056174	1.620	ENSMUST00000115100.1 ENSMUST00000040309.8	Iqcg	IQ motif containing G
chr1_-_172590463	1.618	ENSMUST00000065679.6	Slamf8	SLAM family member 8
chr15_+_79348061	1.603	ENSMUST00000163691.1	Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr17_+_56005672	1.595	ENSMUST00000133998.1	Mpnd	MPN domain containing
chr19_+_53529100	1.595	ENSMUST00000038287.6	Dusp5	dual specificity phosphatase 5
chr9_-_32344237	1.591	ENSMUST00000034533.5	Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5
chr11_-_48994172	1.585	ENSMUST00000146439.1	Tgtp1	T cell specific GTPase 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.9	55.6	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
3.1	9.2	GO:0072554	arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
2.7	8.1	GO:0016115	terpenoid catabolic process(GO:0016115)
2.6	7.9	GO:0032916	positive regulation of transforming growth factor beta3 production(GO:0032916)
2.5	7.6	GO:0071579	regulation of zinc ion transport(GO:0071579)
2.5	12.3	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.4	7.2	GO:0070428	granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
2.4	2.4	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
2.2	10.9	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
2.1	6.3	GO:0097350	neutrophil clearance(GO:0097350)
2.1	22.6	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
2.0	6.0	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.9	5.8	GO:0006116	NADH oxidation(GO:0006116)
1.6	19.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
1.5	8.8	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
1.4	5.6	GO:0002175	protein localization to paranode region of axon(GO:0002175)
1.2	3.7	GO:0090403	regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) oxidative stress-induced premature senescence(GO:0090403)
1.2	8.4	GO:0098535	de novo centriole assembly(GO:0098535)
1.1	9.0	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
1.1	4.4	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.0	1.0	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
1.0	4.2	GO:0090235	regulation of metaphase plate congression(GO:0090235)
1.0	3.8	GO:1903416	negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.9	10.2	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.9	1.8	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.9	2.7	GO:1904170	regulation of bleb assembly(GO:1904170)
0.9	8.8	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.9	2.6	GO:0003349	epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.8	1.6	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.8	3.0	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.7	13.9	GO:0003334	keratinocyte development(GO:0003334)
0.7	8.7	GO:0002467	germinal center formation(GO:0002467)
0.7	6.5	GO:0008063	Toll signaling pathway(GO:0008063)
0.7	2.8	GO:0042414	epinephrine metabolic process(GO:0042414)
0.7	2.1	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.7	4.8	GO:0007296	vitellogenesis(GO:0007296)
0.7	2.0	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.6	4.5	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.6	3.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.6	5.5	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.6	2.4	GO:0030091	protein repair(GO:0030091)
0.6	2.4	GO:0010808	positive regulation of synaptic vesicle priming(GO:0010808)
0.6	2.4	GO:0006545	glycine biosynthetic process(GO:0006545)
0.6	1.7	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.6	1.7	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.6	1.7	GO:2000334	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6	4.5	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.6	3.9	GO:0072553	terminal button organization(GO:0072553)
0.5	3.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.5	1.6	GO:0006657	CDP-choline pathway(GO:0006657)
0.5	2.6	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.5	5.4	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.5	1.4	GO:0090135	actin filament branching(GO:0090135) negative regulation of phospholipase C activity(GO:1900275)
0.5	1.4	GO:1901250	regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.5	2.3	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5	5.9	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.5	4.6	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.5	7.3	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.5	2.3	GO:2000152	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of ubiquitin-specific protease activity(GO:2000152) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.4	2.7	GO:0002553	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.4	4.0	GO:0042095	interferon-gamma biosynthetic process(GO:0042095)
0.4	1.3	GO:0015938	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.4	1.3	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4	1.7	GO:0032621	interleukin-18 production(GO:0032621)
0.4	1.7	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508)
0.4	0.8	GO:1904760	myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.4	5.9	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.4	1.2	GO:0030321	transepithelial chloride transport(GO:0030321) transepithelial ammonium transport(GO:0070634)
0.4	1.6	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.4	2.4	GO:0051013	microtubule severing(GO:0051013)
0.4	5.2	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.4	3.9	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4	1.6	GO:0032382	positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.4	3.5	GO:0048102	autophagic cell death(GO:0048102)
0.4	1.8	GO:0032329	serine transport(GO:0032329)
0.4	1.4	GO:0044793	negative regulation by host of viral process(GO:0044793)
0.4	1.1	GO:0060023	soft palate development(GO:0060023)
0.3	1.6	GO:1990839	response to endothelin(GO:1990839)
0.3	2.6	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3	1.0	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.3	1.9	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	0.9	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3	2.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3	1.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3	0.6	GO:0050688	regulation of defense response to virus(GO:0050688)
0.3	5.4	GO:0038092	nodal signaling pathway(GO:0038092)
0.3	2.5	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.3	1.4	GO:0060536	cartilage morphogenesis(GO:0060536)
0.3	1.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.3	1.1	GO:0006547	histidine metabolic process(GO:0006547)
0.3	1.4	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.3	4.2	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.3	1.3	GO:0015671	oxygen transport(GO:0015671)
0.3	1.3	GO:0006527	arginine catabolic process(GO:0006527)
0.3	2.3	GO:0030259	lipid glycosylation(GO:0030259)
0.2	1.0	GO:1902340	telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.2	1.0	GO:0030043	actin filament fragmentation(GO:0030043)
0.2	2.9	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.2	1.0	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2	1.7	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.2	0.7	GO:1904884	telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2	2.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.2	0.9	GO:0035553	oxidative single-stranded RNA demethylation(GO:0035553)
0.2	0.5	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.2	5.9	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.2	1.9	GO:0032494	response to peptidoglycan(GO:0032494)
0.2	1.1	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.2	7.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2	2.5	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.2	1.3	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2	0.6	GO:2000109	macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109) negative regulation of macrophage apoptotic process(GO:2000110)
0.2	0.8	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.2	2.1	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2	0.4	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2	0.9	GO:0040009	regulation of growth rate(GO:0040009)
0.2	2.8	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.2	14.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2	10.4	GO:0002066	columnar/cuboidal epithelial cell development(GO:0002066)
0.2	1.4	GO:0048625	embryonic hindgut morphogenesis(GO:0048619) myoblast fate commitment(GO:0048625)
0.2	1.6	GO:0070307	lens fiber cell development(GO:0070307)
0.2	2.0	GO:0036158	outer dynein arm assembly(GO:0036158)
0.2	3.4	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.2	2.8	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.2	0.7	GO:1905076	regulation of interleukin-17 secretion(GO:1905076) positive regulation of T-helper 17 type immune response(GO:2000318)
0.2	1.0	GO:0060056	mammary gland involution(GO:0060056)
0.2	0.9	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	0.7	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.2	3.7	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.2	2.5	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	1.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	0.5	GO:0048209	regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.2	0.8	GO:0038032	termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2	0.6	GO:0032289	central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2	0.6	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2	0.6	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.2	1.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.8	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2	0.5	GO:1902414	protein localization to cell junction(GO:1902414)
0.2	1.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.4	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	2.3	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.1	0.4	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.1	1.9	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	4.1	GO:0001709	cell fate determination(GO:0001709)
0.1	1.6	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.5	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	1.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	1.3	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	1.0	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	0.9	GO:0040031	snRNA modification(GO:0040031)
0.1	5.9	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1	0.6	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	2.6	GO:0035082	axoneme assembly(GO:0035082)
0.1	0.6	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.5	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.9	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.3	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	3.2	GO:0060325	face morphogenesis(GO:0060325)
0.1	3.5	GO:0030279	negative regulation of ossification(GO:0030279)
0.1	0.5	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.3	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	1.9	GO:0001967	suckling behavior(GO:0001967)
0.1	0.4	GO:0016266	O-glycan processing(GO:0016266)
0.1	1.1	GO:0003338	metanephros morphogenesis(GO:0003338)
0.1	3.5	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1	0.3	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1	0.2	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.1	0.3	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.1	1.0	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	1.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.1	0.4	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.7	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	0.7	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	1.0	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.1	0.2	GO:2000819	regulation of nucleotide-excision repair(GO:2000819)
0.1	1.7	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.1	0.6	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.3	GO:0090282	positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.1	6.4	GO:0007179	transforming growth factor beta receptor signaling pathway(GO:0007179)
0.1	1.5	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	1.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.8	GO:0042182	ketone catabolic process(GO:0042182)
0.1	1.8	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	1.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.5	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.1	0.2	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	1.2	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.1	1.8	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.2	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.9	GO:0044243	multicellular organism catabolic process(GO:0044243)
0.1	0.1	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.1	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.1	0.3	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1	0.2	GO:0097066	response to thyroid hormone(GO:0097066)
0.1	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.1	0.2	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1	0.5	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	2.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	1.6	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.1	0.8	GO:0097062	dendritic spine maintenance(GO:0097062)
0.1	0.8	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.1	0.2	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.3	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.2	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.8	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.9	GO:0051352	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0	2.5	GO:0006959	humoral immune response(GO:0006959)
0.0	2.3	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.6	GO:0006767	water-soluble vitamin metabolic process(GO:0006767)
0.0	1.0	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.2	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.4	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.1	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.3	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
0.0	0.8	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.4	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.5	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:1903912	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0	0.3	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.7	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.0	1.1	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.4	GO:0030855	epithelial cell differentiation(GO:0030855)
0.0	0.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	2.2	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.8	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.2	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.7	GO:0043954	cellular component maintenance(GO:0043954)
0.0	0.7	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.6	GO:0046686	response to cadmium ion(GO:0046686)
0.0	1.0	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.8	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	3.9	GO:0001822	kidney development(GO:0001822)
0.0	0.4	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.4	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.2	GO:0045176	apical protein localization(GO:0045176)
0.0	2.6	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.3	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	1.1	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.2	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0	0.2	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.4	GO:0048538	thymus development(GO:0048538)
0.0	0.6	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:1904245	regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) viral budding via host ESCRT complex(GO:0039702)
0.0	0.1	GO:0071435	potassium ion export(GO:0071435)
0.0	0.3	GO:0034453	microtubule anchoring(GO:0034453)
0.0	1.2	GO:0007266	Rho protein signal transduction(GO:0007266)
0.0	0.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.0	0.1	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)
0.0	0.8	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321) neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.0	0.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0043652	engulfment of apoptotic cell(GO:0043652)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	22.5	GO:0042613	MHC class II protein complex(GO:0042613)
2.1	14.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
1.8	9.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.6	4.8	GO:0005899	insulin receptor complex(GO:0005899)
1.2	6.0	GO:0031523	Myb complex(GO:0031523)
1.0	6.0	GO:0098536	deuterosome(GO:0098536)
0.9	2.8	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.9	5.4	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.9	3.4	GO:0043293	apoptosome(GO:0043293)
0.7	2.0	GO:0031251	PAN complex(GO:0031251)
0.7	3.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6	7.1	GO:0042612	MHC class I protein complex(GO:0042612)
0.6	2.4	GO:0070552	BRISC complex(GO:0070552)
0.6	2.3	GO:0045098	type III intermediate filament(GO:0045098)
0.5	2.7	GO:0005826	actomyosin contractile ring(GO:0005826)
0.5	7.7	GO:0030127	COPII vesicle coat(GO:0030127)
0.5	1.5	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.4	1.7	GO:0008537	proteasome activator complex(GO:0008537)
0.4	2.4	GO:0044305	calyx of Held(GO:0044305)
0.4	5.9	GO:0035631	CD40 receptor complex(GO:0035631)
0.4	4.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.3	15.2	GO:0002102	podosome(GO:0002102)
0.3	2.4	GO:0001520	outer dense fiber(GO:0001520)
0.3	7.2	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.2	2.7	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2	1.2	GO:1990246	uniplex complex(GO:1990246)
0.2	0.2	GO:0002944	cyclin K-CDK12 complex(GO:0002944)
0.2	1.1	GO:0033270	paranode region of axon(GO:0033270)
0.2	4.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.2	1.4	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	3.2	GO:0032156	septin cytoskeleton(GO:0032156)
0.2	1.8	GO:0036157	outer dynein arm(GO:0036157)
0.2	1.0	GO:0001740	Barr body(GO:0001740)
0.2	3.6	GO:0097431	mitotic spindle pole(GO:0097431)
0.2	3.7	GO:0010369	chromocenter(GO:0010369)
0.2	8.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	0.9	GO:0032389	MutLalpha complex(GO:0032389)
0.2	2.9	GO:0036038	MKS complex(GO:0036038)
0.2	1.6	GO:0042587	glycogen granule(GO:0042587)
0.2	2.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	2.6	GO:0051233	spindle midzone(GO:0051233)
0.2	1.3	GO:0030478	actin cap(GO:0030478)
0.2	3.0	GO:0005640	nuclear outer membrane(GO:0005640) sarcoplasmic reticulum membrane(GO:0033017)
0.2	5.7	GO:0035861	site of double-strand break(GO:0035861)
0.2	1.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	1.3	GO:0005833	hemoglobin complex(GO:0005833)
0.2	2.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.2	0.9	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	1.3	GO:0002177	manchette(GO:0002177)
0.1	0.9	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	2.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	2.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	3.9	GO:0090544	BAF-type complex(GO:0090544)
0.1	0.5	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	1.7	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	12.7	GO:0031225	anchored component of membrane(GO:0031225)
0.1	2.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.4	GO:0042827	platelet dense granule(GO:0042827)
0.1	7.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	4.1	GO:0008180	COP9 signalosome(GO:0008180)
0.1	1.1	GO:0045095	keratin filament(GO:0045095)
0.1	2.8	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	6.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.7	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	0.2	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	4.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	8.9	GO:0000922	spindle pole(GO:0000922)
0.1	1.8	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	0.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	1.3	GO:0001741	XY body(GO:0001741)
0.1	1.1	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.9	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	20.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	5.8	GO:0005902	microvillus(GO:0005902)
0.1	0.2	GO:0036156	inner dynein arm(GO:0036156)
0.1	1.6	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	0.5	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.1	1.1	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	2.8	GO:0005882	intermediate filament(GO:0005882)
0.1	10.1	GO:0043296	apical junction complex(GO:0043296)
0.1	0.6	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.9	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	1.3	GO:0005685	U1 snRNP(GO:0005685)
0.1	0.4	GO:0097422	tubular endosome(GO:0097422)
0.1	2.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	0.2	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
0.0	1.3	GO:0030141	secretory granule(GO:0030141)
0.0	2.6	GO:0031526	brush border membrane(GO:0031526)
0.0	3.5	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.7	GO:0016235	aggresome(GO:0016235)
0.0	15.1	GO:0005925	focal adhesion(GO:0005925)
0.0	2.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	3.8	GO:0030496	midbody(GO:0030496)
0.0	0.3	GO:0031415	NatA complex(GO:0031415)
0.0	0.5	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.5	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	8.1	GO:0043235	receptor complex(GO:0043235)
0.0	2.5	GO:0005814	centriole(GO:0005814)
0.0	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	1.0	GO:0000786	nucleosome(GO:0000786)
0.0	2.0	GO:0005802	trans-Golgi network(GO:0005802)
0.0	3.7	GO:0001726	ruffle(GO:0001726)
0.0	0.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	2.5	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0	0.6	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.7	GO:0097440	apical dendrite(GO:0097440)
0.0	2.2	GO:0016605	PML body(GO:0016605)
0.0	2.5	GO:0055037	recycling endosome(GO:0055037)
0.0	0.8	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	1.4	GO:0010008	endosome membrane(GO:0010008)
0.0	1.9	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.2	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	2.8	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.5	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.6	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	20.9	GO:0070062	extracellular exosome(GO:0070062)
0.0	0.8	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	7.9	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
2.5	12.3	GO:0042289	MHC class II protein binding(GO:0042289)
2.2	19.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
1.5	6.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
1.1	3.3	GO:0016901	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.9	6.6	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.9	5.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.9	5.4	GO:0019841	retinol binding(GO:0019841)
0.9	3.4	GO:1990254	keratin filament binding(GO:1990254)
0.8	2.4	GO:0001565	phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.8	2.4	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.7	4.2	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.7	2.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6	16.6	GO:0042605	peptide antigen binding(GO:0042605)
0.6	1.8	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.6	6.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.6	10.9	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.6	1.7	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.6	2.3	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.6	2.8	GO:0035240	dopamine binding(GO:0035240)
0.6	22.2	GO:0005109	frizzled binding(GO:0005109)
0.6	1.7	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.5	5.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.5	2.7	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5	6.5	GO:0031996	thioesterase binding(GO:0031996)
0.5	4.0	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.5	3.0	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5	3.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.5	1.0	GO:0046977	TAP binding(GO:0046977)
0.5	4.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5	3.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.5	1.9	GO:0004064	arylesterase activity(GO:0004064)
0.5	1.8	GO:0008422	beta-glucosidase activity(GO:0008422)
0.4	1.3	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.4	1.3	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.4	1.6	GO:0048408	epidermal growth factor binding(GO:0048408)
0.4	2.4	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4	3.9	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4	2.0	GO:0046403	polynucleotide 3'-phosphatase activity(GO:0046403)
0.4	1.6	GO:0050632	propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.4	3.0	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.4	2.3	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4	3.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4	15.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.4	1.1	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3	2.4	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.3	7.4	GO:0070410	co-SMAD binding(GO:0070410)
0.3	1.3	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.3	1.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3	1.6	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3	4.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	8.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.3	0.8	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.3	1.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	1.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.2	1.4	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	0.9	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.2	0.9	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.2	3.0	GO:0043495	protein anchor(GO:0043495)
0.2	3.8	GO:0070628	proteasome binding(GO:0070628)
0.2	0.6	GO:0016778	diphosphotransferase activity(GO:0016778)
0.2	1.5	GO:0001849	complement component C1q binding(GO:0001849)
0.2	3.1	GO:0004707	MAP kinase activity(GO:0004707)
0.2	1.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	0.9	GO:0000405	bubble DNA binding(GO:0000405)
0.2	3.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	2.4	GO:0031386	protein tag(GO:0031386)
0.2	9.6	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.2	1.0	GO:0070492	sialic acid binding(GO:0033691) oligosaccharide binding(GO:0070492)
0.2	1.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.2	1.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	0.8	GO:0042809	vitamin D receptor binding(GO:0042809)
0.2	1.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2	1.2	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.2	2.0	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2	2.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.6	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	2.6	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	6.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	0.8	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	4.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	4.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.4	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	0.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.4	GO:0097677	STAT family protein binding(GO:0097677)
0.1	1.6	GO:0052744	phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1	0.6	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1	1.0	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.8	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.7	GO:0032405	MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1	0.5	GO:0032356	oxidized DNA binding(GO:0032356)
0.1	2.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	1.1	GO:0019215	intermediate filament binding(GO:0019215)
0.1	2.4	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	2.0	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	10.8	GO:0005178	integrin binding(GO:0005178)
0.1	3.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	0.4	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	3.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	0.6	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1	1.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.6	GO:0015288	porin activity(GO:0015288)
0.1	0.4	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	4.1	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	1.6	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	5.0	GO:0019003	GDP binding(GO:0019003)
0.1	0.4	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	1.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.4	GO:0034452	dynactin binding(GO:0034452)
0.1	1.0	GO:0030553	cGMP binding(GO:0030553)
0.1	0.3	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	0.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	0.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	11.2	GO:0051015	actin filament binding(GO:0051015)
0.1	4.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.8	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.6	GO:0030957	Tat protein binding(GO:0030957)
0.1	1.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	2.4	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.5	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	2.4	GO:0032452	histone demethylase activity(GO:0032452)
0.1	0.6	GO:0008430	selenium binding(GO:0008430)
0.1	0.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.3	GO:0004849	uridine kinase activity(GO:0004849)
0.0	34.7	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0	0.2	GO:0004103	choline kinase activity(GO:0004103)
0.0	2.0	GO:0017022	myosin binding(GO:0017022)
0.0	1.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	1.1	GO:0097602	cullin family protein binding(GO:0097602)
0.0	1.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.9	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.4	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	1.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0002151	G-quadruplex RNA binding(GO:0002151) poly(G) binding(GO:0034046)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.3	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	1.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	2.8	GO:0004386	helicase activity(GO:0004386)
0.0	0.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	1.4	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	1.4	GO:0005179	hormone activity(GO:0005179)
0.0	1.4	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	1.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.8	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	1.3	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.3	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	9.2	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.9	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	2.2	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.3	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	2.3	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	3.1	GO:0005525	GTP binding(GO:0005525)
0.0	0.4	GO:0051018	protein kinase A binding(GO:0051018)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	7.9	PID_LPA4_PATHWAY	LPA4-mediated signaling events
0.4	14.8	ST_TUMOR_NECROSIS_FACTOR_PATHWAY	Tumor Necrosis Factor Pathway.
0.3	17.5	PID_RET_PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.3	7.1	PID_PRL_SIGNALING_EVENTS_PATHWAY	Signaling events mediated by PRL
0.3	17.5	PID_ILK_PATHWAY	Integrin-linked kinase signaling
0.3	12.9	PID_PS1_PATHWAY	Presenilin action in Notch and Wnt signaling
0.2	9.4	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	1.5	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	19.5	WNT_SIGNALING	Genes related to Wnt-mediated signal transduction
0.2	0.6	PID_IL23_PATHWAY	IL23-mediated signaling events
0.2	3.8	PID_CD40_PATHWAY	CD40/CD40L signaling
0.1	6.4	PID_ATF2_PATHWAY	ATF-2 transcription factor network
0.1	5.5	PID_DELTA_NP63_PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	2.6	PID_P38_MKK3_6PATHWAY	p38 MAPK signaling pathway
0.1	9.3	PID_RHOA_REG_PATHWAY	Regulation of RhoA activity
0.1	5.0	PID_AURORA_B_PATHWAY	Aurora B signaling
0.1	1.3	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events
0.1	1.9	ST_WNT_BETA_CATENIN_PATHWAY	Wnt/beta-catenin Pathway
0.1	3.4	ST_G_ALPHA_I_PATHWAY	G alpha i Pathway
0.1	9.1	PID_SMAD2_3NUCLEAR_PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	3.5	PID_FAK_PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	3.3	PID_AJDISS_2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	4.2	PID_CDC42_PATHWAY	CDC42 signaling events
0.1	2.0	PID_DNA_PK_PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	2.0	PID_IL12_2PATHWAY	IL12-mediated signaling events
0.1	7.6	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	1.9	PID_HNF3A_PATHWAY	FOXA1 transcription factor network
0.0	6.0	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	4.2	PID_MYC_ACTIV_PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	3.0	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	PID_CIRCADIAN_PATHWAY	Circadian rhythm pathway
0.0	1.4	PID_AP1_PATHWAY	AP-1 transcription factor network
0.0	1.2	PID_TELOMERASE_PATHWAY	Regulation of Telomerase
0.0	1.0	PID_INTEGRIN1_PATHWAY	Beta1 integrin cell surface interactions
0.0	0.2	PID_THROMBIN_PAR4_PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.5	PID_FOXM1_PATHWAY	FOXM1 transcription factor network
0.0	0.1	ST_GRANULE_CELL_SURVIVAL_PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.4	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.0	PID_REG_GR_PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	PID_TOLL_ENDOGENOUS_PATHWAY	Endogenous TLR signaling
0.0	0.4	PID_VEGFR1_2_PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.2	REACTOME_ENDOGENOUS_STEROLS	Genes involved in Endogenous sterols
0.5	10.4	REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.5	8.5	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	Genes involved in Notch-HLH transcription pathway
0.5	6.8	REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4	7.2	REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3	7.9	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	6.5	REACTOME_SIGNAL_ATTENUATION	Genes involved in Signal attenuation
0.3	5.4	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.3	4.1	REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3	2.8	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	Genes involved in Regulation of gene expression in beta cells
0.3	4.1	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.3	2.8	REACTOME_AMINE_DERIVED_HORMONES	Genes involved in Amine-derived hormones
0.3	7.6	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	2.1	REACTOME_SIGNALING_BY_FGFR3_MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.2	11.2	REACTOME_NCAM1_INTERACTIONS	Genes involved in NCAM1 interactions
0.2	18.1	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.2	5.3	REACTOME_SIGNALING_BY_HIPPO	Genes involved in Signaling by Hippo
0.2	5.9	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	6.7	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	1.6	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	3.8	REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	1.8	REACTOME_HDL_MEDIATED_LIPID_TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	2.4	REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	2.9	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	7.6	REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	0.7	REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	2.3	REACTOME_SYNTHESIS_OF_PC	Genes involved in Synthesis of PC
0.1	2.0	REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	6.9	REACTOME_G_ALPHA1213_SIGNALLING_EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	2.6	REACTOME_EXTENSION_OF_TELOMERES	Genes involved in Extension of Telomeres
0.1	1.5	REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	2.2	REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.3	REACTOME_NEPHRIN_INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.6	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	3.8	REACTOME_RNA_POL_I_PROMOTER_OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	2.4	REACTOME_SYNTHESIS_OF_PA	Genes involved in Synthesis of PA
0.1	5.4	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	0.9	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	2.4	REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	0.6	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.1	REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER	Genes involved in Formation of incision complex in GG-NER
0.1	1.8	REACTOME_TIGHT_JUNCTION_INTERACTIONS	Genes involved in Tight junction interactions
0.1	5.4	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.4	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.2	REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME_REGULATION_OF_COMPLEMENT_CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME_MTORC1_MEDIATED_SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.5	REACTOME_GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	1.6	REACTOME_MRNA_3_END_PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.8	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.8	REACTOME_SULFUR_AMINO_ACID_METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	2.9	REACTOME_MITOTIC_PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	2.7	REACTOME_INTERFERON_SIGNALING	Genes involved in Interferon Signaling
0.0	1.5	REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.4	REACTOME_DEADENYLATION_OF_MRNA	Genes involved in Deadenylation of mRNA
0.0	0.8	REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.5	REACTOME_SIGNAL_TRANSDUCTION_BY_L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME_CALNEXIN_CALRETICULIN_CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME_NOD1_2_SIGNALING_PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.5	REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME_ACTIVATION_OF_RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME_PYRIMIDINE_METABOLISM	Genes involved in Pyrimidine metabolism

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