Motif ID: Rfx2_Rfx7
Z-value: 1.363
Transcription factors associated with Rfx2_Rfx7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rfx2 | ENSMUSG00000024206.8 | Rfx2 |
| Rfx7 | ENSMUSG00000037674.9 | Rfx7 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rfx7 | mm10_v2_chr9_+_72532214_72532271 | 0.19 | 2.4e-01 | Click! |
| Rfx2 | mm10_v2_chr17_-_56830916_56831008 | -0.10 | 5.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 6.3 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 1.3 | 2.6 | GO:0002669 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
| 1.3 | 3.8 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.6 | 10.9 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.6 | 1.7 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
| 0.6 | 2.8 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.5 | 2.2 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.5 | 3.0 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.5 | 1.9 | GO:2000832 | androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843) |
| 0.4 | 1.3 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.4 | 4.3 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.4 | 2.1 | GO:1904717 | positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717) |
| 0.4 | 4.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.4 | 2.0 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
| 0.4 | 1.2 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
| 0.4 | 1.1 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 0.3 | 1.7 | GO:0015871 | choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.3 | 1.0 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
| 0.3 | 2.6 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
| 0.3 | 1.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 0.3 | 0.9 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.3 | 0.8 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.3 | 1.0 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.2 | 2.6 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.2 | 1.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.2 | 0.6 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.2 | 6.7 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.2 | 0.7 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.2 | 2.5 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.2 | 0.5 | GO:1903538 | meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.2 | 0.7 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.2 | 0.8 | GO:0006537 | glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543) |
| 0.2 | 0.5 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 0.8 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 0.4 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.9 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.1 | 0.9 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.1 | 1.3 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.1 | 0.5 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.1 | 0.4 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.1 | 1.3 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 0.5 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.1 | 0.4 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401) |
| 0.1 | 2.1 | GO:0055098 | response to low-density lipoprotein particle(GO:0055098) |
| 0.1 | 0.8 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
| 0.1 | 0.7 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.1 | 2.1 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.1 | 0.7 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 2.2 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.1 | 0.9 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 0.2 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 1.3 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.1 | 0.3 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.1 | 0.3 | GO:1903564 | regulation of protein localization to cilium(GO:1903564) |
| 0.1 | 0.4 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.1 | 1.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.1 | 1.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.1 | 1.4 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.4 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.1 | 1.7 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.1 | 0.4 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.1 | 0.8 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 0.6 | GO:0032055 | negative regulation of translation in response to stress(GO:0032055) positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.1 | 7.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 4.1 | GO:1901381 | positive regulation of potassium ion transmembrane transport(GO:1901381) |
| 0.1 | 0.8 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.1 | 0.9 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 1.4 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.1 | 0.3 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.3 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.1 | 1.3 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.1 | 0.9 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.1 | 0.8 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.1 | 0.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.4 | GO:0030223 | neutrophil differentiation(GO:0030223) |
| 0.1 | 2.2 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.1 | 2.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 0.5 | GO:0021886 | female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.1 | 3.5 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 0.3 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.1 | 0.2 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.1 | 3.5 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 0.4 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.1 | 0.2 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.1 | 1.2 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.1 | 0.2 | GO:0060282 | positive regulation of oocyte development(GO:0060282) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 0.1 | 1.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 4.0 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 0.4 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.1 | 0.7 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 0.2 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
| 0.0 | 1.3 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.0 | 0.5 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 1.3 | GO:0002437 | inflammatory response to antigenic stimulus(GO:0002437) |
| 0.0 | 0.1 | GO:2001013 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.0 | 0.2 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.0 | 0.1 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.0 | 1.0 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.0 | 0.9 | GO:0033198 | response to ATP(GO:0033198) |
| 0.0 | 0.2 | GO:0010882 | regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882) |
| 0.0 | 0.3 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.0 | 0.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.0 | 0.2 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 0.3 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.0 | 0.2 | GO:0019659 | fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.0 | 0.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.0 | 1.5 | GO:0061371 | determination of heart left/right asymmetry(GO:0061371) |
| 0.0 | 0.4 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.0 | 0.4 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 1.5 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.0 | 0.8 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 0.1 | GO:0090148 | membrane fission(GO:0090148) |
| 0.0 | 0.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.6 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.9 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.0 | 0.2 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.0 | 0.6 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 2.4 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.2 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.0 | 0.3 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.2 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.0 | 0.1 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.0 | 2.0 | GO:0034620 | cellular response to unfolded protein(GO:0034620) |
| 0.0 | 0.1 | GO:2000078 | positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220) positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.0 | 0.7 | GO:0007099 | centriole replication(GO:0007099) |
| 0.0 | 0.4 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.0 | 0.5 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.0 | 1.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.0 | 0.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.0 | 0.3 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 0.6 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 0.0 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
| 0.0 | 2.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.5 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 1.7 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 0.4 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.0 | 0.1 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.3 | GO:0035357 | peroxisome proliferator activated receptor signaling pathway(GO:0035357) |
| 0.0 | 0.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.2 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.2 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 1.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.0 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
| 0.0 | 1.5 | GO:2000177 | regulation of neural precursor cell proliferation(GO:2000177) |
| 0.0 | 0.2 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 0.1 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.0 | 0.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.1 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
| 0.0 | 0.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.1 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.0 | 0.2 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.0 | 0.1 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.3 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 0.1 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 10.9 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.6 | 2.5 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.5 | 2.8 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.5 | 1.9 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.3 | 4.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 1.5 | GO:0070695 | FHF complex(GO:0070695) |
| 0.2 | 1.0 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.2 | 2.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.2 | 0.8 | GO:0071942 | XPC complex(GO:0071942) |
| 0.2 | 0.9 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.2 | 2.1 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 3.0 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 0.6 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.1 | 0.3 | GO:0036156 | inner dynein arm(GO:0036156) |
| 0.1 | 0.4 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.1 | 5.0 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 1.2 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.1 | 1.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 1.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 1.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.9 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 0.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 1.6 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 3.4 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 0.9 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 0.4 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.1 | 1.9 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 3.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 2.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 1.7 | GO:0097546 | ciliary base(GO:0097546) |
| 0.1 | 0.2 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.1 | 0.8 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 0.4 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 4.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 1.3 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.4 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 3.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.0 | 3.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.3 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 1.4 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 1.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.3 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.9 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 1.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.2 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 3.5 | GO:0030017 | sarcomere(GO:0030017) |
| 0.0 | 1.8 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.8 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 0.5 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.9 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 1.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.2 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 0.6 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.4 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 0.0 | 0.1 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.0 | 0.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.0 | 0.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.0 | 0.1 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 0.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.3 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.0 | GO:1990246 | uniplex complex(GO:1990246) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 10.9 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.7 | 2.9 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.6 | 2.6 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.5 | 2.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.4 | 1.3 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.4 | 4.9 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.4 | 1.2 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.4 | 1.9 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.3 | 1.0 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.3 | 2.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.3 | 1.0 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.3 | 2.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.3 | 1.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.3 | 1.0 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
| 0.2 | 2.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 3.8 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 1.0 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.2 | 1.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 6.3 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 0.6 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.2 | 1.9 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.2 | 0.6 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.2 | 1.3 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.2 | 0.2 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.2 | 0.8 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 1.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 0.4 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.1 | 1.0 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 0.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 0.8 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 0.4 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.1 | 0.2 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.1 | 0.6 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
| 0.1 | 0.4 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 0.1 | 0.4 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.1 | 2.3 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 0.4 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 0.1 | 1.2 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.1 | 1.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.1 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 0.5 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 1.2 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 0.4 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 2.0 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 4.1 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 0.8 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 2.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 1.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 0.1 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.1 | 0.7 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 2.5 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 1.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 0.8 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.2 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.1 | 0.2 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 0.1 | 0.2 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 0.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 1.1 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.8 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 2.6 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 5.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.2 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.0 | 0.7 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.0 | 0.8 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.3 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.0 | 0.5 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 3.1 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.0 | 0.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.9 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.7 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 0.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.0 | 0.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.3 | GO:0005047 | signal recognition particle binding(GO:0005047) 7S RNA binding(GO:0008312) TPR domain binding(GO:0030911) |
| 0.0 | 0.5 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.0 | 0.1 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.0 | 0.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.3 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.0 | 0.5 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.0 | 8.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.1 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
| 0.0 | 0.1 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.0 | 0.7 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 1.1 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 3.5 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 2.0 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 1.4 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.2 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.0 | 0.1 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.0 | 0.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.1 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.0 | 0.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.0 | 0.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.1 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
| 0.0 | 0.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 0.4 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 1.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.3 | GO:1900750 | glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.0 | 0.0 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.0 | 0.8 | GO:0020037 | heme binding(GO:0020037) |
| 0.0 | 0.3 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.5 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 0.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 2.9 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.1 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.0 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.0 | 0.4 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.2 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 1.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.0 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 3.8 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 0.8 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 9.1 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.1 | 2.2 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 2.5 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 2.0 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.2 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.1 | 0.9 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 1.3 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 2.1 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 1.3 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.0 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.8 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.0 | 1.0 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 0.9 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 1.1 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.5 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 1.5 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.1 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.4 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.3 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.4 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.7 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.2 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.3 | 6.3 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 2.5 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 2.2 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 4.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 3.5 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 1.9 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 2.6 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 9.0 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.1 | 6.9 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 2.6 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 2.6 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 0.6 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 0.9 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.3 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 1.1 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.9 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.7 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 3.3 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.5 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 1.2 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.7 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 1.0 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 2.6 | REACTOME_REGULATION_OF_INSULIN_SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.0 | 1.1 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.0 | 1.5 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 1.3 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.4 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.5 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.8 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.6 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.2 | REACTOME_TELOMERE_MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.0 | 0.2 | REACTOME_SIGNALING_BY_ERBB4 | Genes involved in Signaling by ERBB4 |
| 0.0 | 0.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 1.1 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.8 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.4 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.2 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.0 | 0.4 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.2 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.1 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.3 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | Genes involved in Integration of energy metabolism |
|
|
|