Motif ID: Rfx3_Rfx1_Rfx4

Z-value: 3.478

Transcription factors associated with Rfx3_Rfx1_Rfx4:

Gene SymbolEntrez IDGene Name
Rfx1 ENSMUSG00000031706.6 Rfx1
Rfx3 ENSMUSG00000040929.10 Rfx3
Rfx4 ENSMUSG00000020037.9 Rfx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx4mm10_v2_chr10_+_84838143_84838153-0.279.2e-02Click!
Rfx1mm10_v2_chr8_+_84066824_84066882-0.202.2e-01Click!
Rfx3mm10_v2_chr19_-_28010995_28011054-0.086.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx3_Rfx1_Rfx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_60925612 59.487 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr18_+_60925644 24.428 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr15_+_98167806 22.273 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr5_+_24985840 19.669 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr4_-_119415494 17.936 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chrX_+_7919816 17.806 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_-_140082489 17.671 ENSMUST00000026541.7
Caly
calcyon neuron-specific vesicular protein
chr7_-_140082246 17.488 ENSMUST00000166758.2
Caly
calcyon neuron-specific vesicular protein
chr7_-_31051431 15.666 ENSMUST00000073892.4
Fxyd7
FXYD domain-containing ion transport regulator 7
chr8_+_94772009 14.484 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr11_-_105944412 14.268 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
Cyb561


cytochrome b-561


chr9_+_59589288 13.290 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr7_+_99268338 12.765 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chr12_-_84148449 12.311 ENSMUST00000061425.2
Pnma1
paraneoplastic antigen MA1
chr2_+_121289589 11.805 ENSMUST00000094639.3
Map1a
microtubule-associated protein 1 A
chr7_-_4546567 11.540 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr11_-_105944128 11.290 ENSMUST00000184086.1
Cyb561
cytochrome b-561
chr13_+_91461050 11.265 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr19_-_57197377 11.122 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197496 10.923 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr7_+_16959714 10.892 ENSMUST00000038163.6
Pnmal1
PNMA-like 1
chr19_-_57197435 10.879 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197556 10.717 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr16_-_16829276 10.174 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr10_-_81472859 9.983 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chr13_+_24845122 9.919 ENSMUST00000006893.8
D130043K22Rik
RIKEN cDNA D130043K22 gene
chr4_+_123183456 9.791 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr1_-_60043087 9.653 ENSMUST00000027172.6
Ica1l
islet cell autoantigen 1-like
chr17_+_46254017 9.646 ENSMUST00000095262.4
Lrrc73
leucine rich repeat containing 73
chr1_+_66386968 9.592 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr7_+_131966446 9.570 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr4_+_129960760 9.311 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr17_+_34629533 9.284 ENSMUST00000015620.6
Prrt1
proline-rich transmembrane protein 1
chr4_+_57434247 9.083 ENSMUST00000102905.1
Palm2
paralemmin 2
chr7_+_3303643 8.893 ENSMUST00000172109.1
Prkcg
protein kinase C, gamma
chr5_-_92042630 8.733 ENSMUST00000113140.1
ENSMUST00000113143.1
Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr8_-_95142477 8.705 ENSMUST00000034240.7
ENSMUST00000169748.1
Kifc3

kinesin family member C3

chr15_+_54745702 8.651 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr7_+_3303503 8.520 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr1_-_87510306 8.371 ENSMUST00000027477.8
Ngef
neuronal guanine nucleotide exchange factor
chr19_-_46327121 8.362 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr5_-_142550965 8.308 ENSMUST00000129212.1
ENSMUST00000110785.1
ENSMUST00000063635.8
Radil


Ras association and DIL domains


chr2_-_118256929 8.248 ENSMUST00000028820.6
ENSMUST00000028821.3
Fsip1

fibrous sheath-interacting protein 1

chr11_+_43474276 8.013 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr3_-_88459047 7.820 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr3_-_88458876 7.767 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr1_+_161142706 7.639 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr4_+_152338619 7.636 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr4_+_152338887 7.490 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr9_+_47530173 7.432 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr7_+_45785331 7.329 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr12_-_69790660 7.309 ENSMUST00000021377.4
Cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr5_+_120431770 7.296 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr15_-_33687840 7.261 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr1_+_161142661 7.218 ENSMUST00000125018.1
Ankrd45
ankyrin repeat domain 45
chr9_-_121839460 7.146 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr4_+_137681663 7.063 ENSMUST00000047243.5
Rap1gap
Rap1 GTPase-activating protein
chr7_+_126847908 7.028 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr18_+_23803962 7.002 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr7_+_3390629 6.677 ENSMUST00000182222.1
Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr5_+_21424934 6.650 ENSMUST00000056045.4
Fam185a
family with sequence similarity 185, member A
chr10_-_13868932 6.587 ENSMUST00000019942.5
ENSMUST00000162610.1
Aig1

androgen-induced 1

chr11_+_87760533 6.546 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr7_+_16944645 6.464 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr10_-_13868779 6.108 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr11_-_74897052 6.103 ENSMUST00000057631.5
ENSMUST00000081799.5
Sgsm2

small G protein signaling modulator 2

chr11_+_70029742 6.102 ENSMUST00000132597.2
Dlg4
discs, large homolog 4 (Drosophila)
chr13_+_55464237 6.006 ENSMUST00000046533.7
Prr7
proline rich 7 (synaptic)
chr11_-_89302545 5.960 ENSMUST00000061728.3
Nog
noggin
chr8_-_64733534 5.696 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chr9_-_60688118 5.668 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr15_+_89532816 5.574 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr10_+_34297421 5.573 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr7_+_139894696 5.469 ENSMUST00000151421.1
ENSMUST00000053445.9
ENSMUST00000121839.1
Kndc1


kinase non-catalytic C-lobe domain (KIND) containing 1


chr17_+_27685197 5.468 ENSMUST00000097360.2
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr2_-_30048827 5.459 ENSMUST00000113711.2
Wdr34
WD repeat domain 34
chr1_-_84696182 5.426 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr5_+_111581422 5.414 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr7_+_133776857 5.325 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
Fank1


fibronectin type 3 and ankyrin repeat domains 1


chr12_+_5411641 5.136 ENSMUST00000163627.1
2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr19_+_47178820 5.056 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr15_+_82256023 5.043 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr4_-_153482768 5.011 ENSMUST00000105646.2
Ajap1
adherens junction associated protein 1
chr12_+_113140198 5.010 ENSMUST00000084882.4
Crip2
cysteine rich protein 2
chr11_-_116335384 4.984 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr12_+_80518990 4.974 ENSMUST00000021558.6
Galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr6_-_115838412 4.962 ENSMUST00000032468.5
ENSMUST00000184428.1
Efcab12

EF-hand calcium binding domain 12

chr3_-_89245005 4.922 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr8_-_22805596 4.872 ENSMUST00000163739.1
Ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr2_-_118703963 4.812 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr5_-_103211251 4.765 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr3_+_82358056 4.714 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr8_+_123212857 4.713 ENSMUST00000060133.6
Spata33
spermatogenesis associated 33
chr15_-_98953541 4.699 ENSMUST00000097014.5
Tuba1a
tubulin, alpha 1A
chr11_-_61453992 4.672 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
Rnf112


ring finger protein 112


chr3_-_89245159 4.631 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr9_-_29412204 4.618 ENSMUST00000115237.1
Ntm
neurotrimin
chr9_+_59578192 4.599 ENSMUST00000118549.1
ENSMUST00000034840.3
Celf6

CUGBP, Elav-like family member 6

chr3_-_126998408 4.574 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr19_+_45560569 4.563 ENSMUST00000047057.7
Dpcd
deleted in primary ciliary dyskinesia
chr2_+_71981184 4.532 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr9_-_70141484 4.526 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr11_-_67965631 4.390 ENSMUST00000021287.5
ENSMUST00000126766.1
Wdr16

WD repeat domain 16

chr16_+_14906622 4.384 ENSMUST00000090277.1
Efcab1
EF hand calcium binding domain 1
chr17_+_28142267 4.321 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3
chr17_-_85090204 4.320 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr7_+_19176416 4.318 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr11_-_6606053 4.272 ENSMUST00000045713.3
Nacad
NAC alpha domain containing
chr2_-_5714490 4.221 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr3_+_29082539 4.208 ENSMUST00000119598.1
ENSMUST00000118531.1
Egfem1

EGF-like and EMI domain containing 1

chr9_-_110476637 4.192 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr8_-_111933761 4.159 ENSMUST00000034429.7
Tmem231
transmembrane protein 231
chr9_+_82829806 4.143 ENSMUST00000113245.2
ENSMUST00000034783.4
Irak1bp1

interleukin-1 receptor-associated kinase 1 binding protein 1

chr7_-_118705708 4.139 ENSMUST00000038791.8
Gde1
glycerophosphodiester phosphodiesterase 1
chr15_-_79062866 4.124 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr11_-_76468396 4.088 ENSMUST00000065028.7
Abr
active BCR-related gene
chr9_+_63602650 4.050 ENSMUST00000041551.7
Aagab
alpha- and gamma-adaptin binding protein
chrX_+_36195938 4.031 ENSMUST00000048067.3
Zcchc12
zinc finger, CCHC domain containing 12
chr2_+_118663235 3.982 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_124598749 3.969 ENSMUST00000130912.1
ENSMUST00000100706.3
Tctn2

tectonic family member 2

chrX_+_36195904 3.955 ENSMUST00000115258.2
Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_136590841 3.954 ENSMUST00000138047.1
ENSMUST00000145648.1
Tceal3

transcription elongation factor A (SII)-like 3

chr9_-_106685892 3.953 ENSMUST00000169068.1
ENSMUST00000046735.4
Tex264

testis expressed gene 264

chrX_+_36195950 3.941 ENSMUST00000115257.1
Zcchc12
zinc finger, CCHC domain containing 12
chr13_+_42681513 3.914 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr5_-_136170634 3.792 ENSMUST00000041048.1
Orai2
ORAI calcium release-activated calcium modulator 2
chr11_+_49794157 3.688 ENSMUST00000020629.4
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr13_-_49309217 3.682 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr13_-_92483996 3.671 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr9_-_106685653 3.610 ENSMUST00000163441.1
Tex264
testis expressed gene 264
chr6_-_90810118 3.601 ENSMUST00000101151.3
Iqsec1
IQ motif and Sec7 domain 1
chr1_-_172329261 3.592 ENSMUST00000062387.2
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr5_-_115652974 3.566 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr13_-_49320219 3.564 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chrX_+_36195968 3.522 ENSMUST00000115256.1
Zcchc12
zinc finger, CCHC domain containing 12
chr11_-_59839745 3.479 ENSMUST00000141415.1
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr11_-_72361837 3.402 ENSMUST00000108503.2
Tekt1
tektin 1
chr7_-_44375006 3.390 ENSMUST00000107933.1
1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr11_+_53567361 3.364 ENSMUST00000057330.8
ENSMUST00000120613.2
ENSMUST00000173744.1
ENSMUST00000118353.2
Kif3a



kinesin family member 3A



chr2_-_164857542 3.360 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr8_-_27202542 3.324 ENSMUST00000038174.6
Got1l1
glutamic-oxaloacetic transaminase 1-like 1
chr16_-_3909192 3.293 ENSMUST00000181699.1
1700016D08Rik
RIKEN cDNA 1700016D08 gene
chr9_+_110476985 3.265 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
Kif9



kinesin family member 9



chr17_-_87446854 3.209 ENSMUST00000040440.6
Calm2
calmodulin 2
chr4_+_105790534 3.163 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr17_+_12119274 3.154 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr8_-_106337987 3.153 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr4_+_126058557 3.153 ENSMUST00000035497.4
Oscp1
organic solute carrier partner 1
chr7_-_13054665 3.090 ENSMUST00000182515.1
ENSMUST00000069289.8
Mzf1

myeloid zinc finger 1

chr3_-_89214378 3.084 ENSMUST00000073572.4
Mtx1
metaxin 1
chr7_+_116504363 3.082 ENSMUST00000032895.8
Nucb2
nucleobindin 2
chr11_-_59839828 3.080 ENSMUST00000019517.3
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr3_+_13946368 3.077 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr1_-_152766281 3.059 ENSMUST00000111859.1
ENSMUST00000148865.1
Rgl1

ral guanine nucleotide dissociation stimulator,-like 1

chr10_+_80299084 3.030 ENSMUST00000154212.1
Apc2
adenomatosis polyposis coli 2
chr3_+_65109343 3.024 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr5_-_137531204 3.024 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr7_+_16738410 3.017 ENSMUST00000086112.6
Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr6_+_34780836 3.015 ENSMUST00000115012.1
ENSMUST00000115014.1
ENSMUST00000115009.1
Agbl3


ATP/GTP binding protein-like 3


chr17_-_25837082 3.014 ENSMUST00000183929.1
ENSMUST00000184865.1
ENSMUST00000026831.7
Rhbdl1


rhomboid, veinlet-like 1 (Drosophila)


chr7_+_116504409 3.003 ENSMUST00000183175.1
Nucb2
nucleobindin 2
chr6_+_83156401 2.994 ENSMUST00000032106.4
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr18_-_12305638 2.964 ENSMUST00000122408.1
ENSMUST00000118525.1
ENSMUST00000142066.1
Ankrd29


ankyrin repeat domain 29


chr17_-_31277327 2.961 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr10_+_122678764 2.954 ENSMUST00000161487.1
ENSMUST00000067918.5
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr5_-_124187150 2.938 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr8_-_78821136 2.927 ENSMUST00000130325.1
ENSMUST00000051867.6
Lsm6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr16_-_3908596 2.921 ENSMUST00000123235.2
1700037C18Rik
RIKEN cDNA 1700037C18 gene
chr3_+_90079540 2.918 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr18_-_77047282 2.913 ENSMUST00000154665.1
ENSMUST00000026486.6
ENSMUST00000123650.1
ENSMUST00000126153.1
Katnal2



katanin p60 subunit A-like 2



chr3_-_127225847 2.911 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr4_-_117125618 2.877 ENSMUST00000183310.1
Btbd19
BTB (POZ) domain containing 19
chr12_+_29528382 2.868 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr3_+_67374116 2.835 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr6_+_88084473 2.813 ENSMUST00000032143.6
Rpn1
ribophorin I
chr3_+_118433797 2.809 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr17_+_85620816 2.808 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr19_-_4283033 2.807 ENSMUST00000167215.1
ENSMUST00000056888.6
Ankrd13d

ankyrin repeat domain 13 family, member D

chr11_+_75999912 2.803 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr4_+_109343029 2.763 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr17_-_80290476 2.757 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr15_-_71727815 2.740 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr3_-_127225917 2.717 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr2_+_152962485 2.699 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr8_-_119575143 2.697 ENSMUST00000036049.4
Hsdl1
hydroxysteroid dehydrogenase like 1
chr9_+_107547288 2.685 ENSMUST00000010188.7
Zmynd10
zinc finger, MYND domain containing 10
chr15_+_76671615 2.680 ENSMUST00000037551.8
Ppp1r16a
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr8_-_84104773 2.670 ENSMUST00000041367.7
Dcaf15
DDB1 and CUL4 associated factor 15
chr1_-_152766323 2.662 ENSMUST00000111857.1
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chrX_+_136993147 2.650 ENSMUST00000113067.1
ENSMUST00000101227.2
Zcchc18

zinc finger, CCHC domain containing 18

chr8_+_85060055 2.645 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr3_+_67374091 2.643 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr11_-_29247208 2.638 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr12_-_72070991 2.623 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr7_-_45830776 2.623 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr8_+_36993551 2.619 ENSMUST00000098825.3
AI429214
expressed sequence AI429214
chr2_-_91444622 2.602 ENSMUST00000064652.7
ENSMUST00000102594.4
ENSMUST00000094835.2
1110051M20Rik


RIKEN cDNA 1110051M20 gene


chr6_+_34780412 2.601 ENSMUST00000115016.1
ENSMUST00000115017.1
Agbl3

ATP/GTP binding protein-like 3

chr16_+_3908801 2.598 ENSMUST00000145150.2
ENSMUST00000040881.7
Cluap1

clusterin associated protein 1

chr5_+_30711564 2.597 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 89.5 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
3.6 14.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
3.5 17.4 GO:0032423 regulation of mismatch repair(GO:0032423)
3.1 15.4 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.9 8.7 GO:1990523 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) bone regeneration(GO:1990523)
2.5 7.4 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
2.3 4.5 GO:0021508 ventral midline development(GO:0007418) floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
2.2 15.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
2.0 6.1 GO:2000836 negative regulation of glucagon secretion(GO:0070093) positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845)
1.8 7.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.7 1.7 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.7 3.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
1.5 6.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.5 8.7 GO:0045218 zonula adherens maintenance(GO:0045218)
1.4 5.6 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
1.4 37.9 GO:0048268 clathrin coat assembly(GO:0048268)
1.3 5.1 GO:0042360 vitamin E metabolic process(GO:0042360)
1.2 5.0 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.2 10.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.1 10.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.1 4.5 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
1.1 3.3 GO:0006532 aspartate biosynthetic process(GO:0006532)
1.1 3.3 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
1.1 3.3 GO:0097402 neuroblast migration(GO:0097402)
1.1 4.3 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
1.1 2.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.0 8.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.0 4.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.9 4.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.9 17.8 GO:0016486 peptide hormone processing(GO:0016486)
0.9 2.8 GO:0016598 protein arginylation(GO:0016598)
0.9 7.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.9 17.9 GO:0071625 vocalization behavior(GO:0071625)
0.8 5.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.8 4.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.8 4.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 2.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.7 5.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.7 3.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.7 15.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.7 8.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.7 14.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.6 4.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.6 2.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.6 3.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.6 2.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 1.7 GO:0015886 heme transport(GO:0015886)
0.5 1.6 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.5 3.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.5 13.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.5 18.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 1.5 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.5 1.9 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.5 41.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.5 1.4 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.5 4.6 GO:0021678 third ventricle development(GO:0021678)
0.5 7.7 GO:0000338 protein deneddylation(GO:0000338)
0.4 1.8 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.4 5.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.4 8.0 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.4 1.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.4 2.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.4 2.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.4 1.2 GO:0043312 neutrophil degranulation(GO:0043312)
0.4 5.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 0.4 GO:2000331 regulation of terminal button organization(GO:2000331)
0.4 1.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 3.8 GO:0006465 signal peptide processing(GO:0006465)
0.4 3.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.4 1.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.4 1.1 GO:0099541 diacylglycerol catabolic process(GO:0046340) retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.4 5.4 GO:0007220 Notch receptor processing(GO:0007220)
0.4 12.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.4 3.9 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 12.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.3 27.5 GO:0022900 electron transport chain(GO:0022900)
0.3 1.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 1.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 9.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 2.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 1.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 2.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 1.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.3 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 22.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 1.3 GO:0048318 axial mesoderm development(GO:0048318)
0.3 1.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 0.8 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.3 0.8 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.7 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.2 13.2 GO:0032418 lysosome localization(GO:0032418)
0.2 1.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 3.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 2.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 4.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 2.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 3.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.2 4.1 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.2 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 2.7 GO:0007398 ectoderm development(GO:0007398)
0.2 9.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 2.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 2.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 0.6 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.2 7.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 1.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 3.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 4.5 GO:0097320 membrane tubulation(GO:0097320)
0.2 3.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 2.2 GO:0060134 prepulse inhibition(GO:0060134)
0.2 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.2 3.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 0.6 GO:0030046 parallel actin filament bundle assembly(GO:0030046) formin-nucleated actin cable assembly(GO:0070649)
0.2 4.5 GO:0060074 synapse maturation(GO:0060074)
0.2 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 1.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 1.0 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 1.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 3.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.2 2.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 2.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 2.2 GO:0030238 male sex determination(GO:0030238)
0.2 1.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 8.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 0.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 1.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.2 0.5 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.2 3.3 GO:0071801 regulation of podosome assembly(GO:0071801)
0.2 6.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 2.5 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 1.1 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 6.1 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.1 4.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 3.6 GO:0010107 potassium ion import(GO:0010107)
0.1 1.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.8 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 2.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.5 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 0.9 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 5.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 3.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 6.4 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 1.2 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 3.6 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.1 2.9 GO:0048665 neuron fate specification(GO:0048665)
0.1 1.5 GO:0001553 luteinization(GO:0001553)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 5.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.2 GO:0042407 cristae formation(GO:0042407)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 2.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.1 2.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.6 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.5 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.3 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.1 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 2.4 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.8 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143) ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 1.0 GO:0097484 dendrite extension(GO:0097484)
0.1 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 1.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.1 0.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 9.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 1.3 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 1.8 GO:0061371 determination of heart left/right asymmetry(GO:0061371)
0.0 0.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 1.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 4.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 4.6 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 2.2 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 1.8 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 1.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0048703 embryonic neurocranium morphogenesis(GO:0048702) embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.2 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 2.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 4.0 GO:0007411 axon guidance(GO:0007411)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 3.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 1.7 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 3.9 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 3.3 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0050965 detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 6.5 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.5 GO:0032355 response to estradiol(GO:0032355)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0090102 cochlea development(GO:0090102)
0.0 2.8 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 1.1 GO:0045333 cellular respiration(GO:0045333)
0.0 0.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.8 GO:0031623 receptor internalization(GO:0031623)
0.0 1.4 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.8 GO:0071166 ribonucleoprotein complex localization(GO:0071166) ribonucleoprotein complex export from nucleus(GO:0071426)
0.0 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
28.0 83.9 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
5.3 21.1 GO:1990769 proximal neuron projection(GO:1990769)
1.3 5.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.1 3.4 GO:0016939 kinesin II complex(GO:0016939)
1.1 9.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.9 4.5 GO:0044316 cone cell pedicle(GO:0044316)
0.8 8.7 GO:0005915 zonula adherens(GO:0005915)
0.8 4.7 GO:0000235 astral microtubule(GO:0000235)
0.7 5.4 GO:0001520 outer dense fiber(GO:0001520)
0.6 2.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.6 7.4 GO:0070852 cell body fiber(GO:0070852)
0.5 8.7 GO:1904115 axon cytoplasm(GO:1904115)
0.5 5.3 GO:0016342 catenin complex(GO:0016342)
0.5 12.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5 9.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.5 3.8 GO:0005787 signal peptidase complex(GO:0005787)
0.4 4.8 GO:0034464 BBSome(GO:0034464)
0.4 1.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4 46.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 5.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 5.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.4 9.8 GO:0034451 centriolar satellite(GO:0034451)
0.4 6.3 GO:0036038 MKS complex(GO:0036038)
0.4 5.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 11.6 GO:0035371 microtubule plus-end(GO:0035371)
0.4 6.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 10.2 GO:0031430 M band(GO:0031430)
0.3 8.7 GO:0005921 gap junction(GO:0005921)
0.3 4.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 3.2 GO:0005688 U6 snRNP(GO:0005688)
0.3 10.1 GO:0097546 ciliary base(GO:0097546)
0.3 3.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 5.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 1.7 GO:0097443 sorting endosome(GO:0097443)
0.3 6.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 1.1 GO:0001651 dense fibrillar component(GO:0001651)
0.2 11.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 0.7 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 1.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.1 GO:1990745 EARP complex(GO:1990745)
0.2 0.2 GO:0098830 presynaptic endosome(GO:0098830)
0.2 2.2 GO:0000815 ESCRT III complex(GO:0000815)
0.2 4.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.6 GO:0005683 U7 snRNP(GO:0005683)
0.2 2.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 0.8 GO:0034709 methylosome(GO:0034709)
0.2 4.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 6.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 0.7 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 1.4 GO:0042382 paraspeckles(GO:0042382)
0.2 1.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 1.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 5.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1 12.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 33.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 2.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 3.3 GO:0002102 podosome(GO:0002102)
0.1 1.1 GO:0005869 dynactin complex(GO:0005869)
0.1 1.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 18.4 GO:0030141 secretory granule(GO:0030141)
0.1 2.4 GO:0010369 chromocenter(GO:0010369)
0.1 4.2 GO:0097440 apical dendrite(GO:0097440)
0.1 8.0 GO:0005581 collagen trimer(GO:0005581)
0.1 1.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.2 GO:0000812 Swr1 complex(GO:0000812)
0.1 2.4 GO:0016235 aggresome(GO:0016235)
0.1 0.7 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 2.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 9.6 GO:0031514 motile cilium(GO:0031514)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 4.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 4.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 3.0 GO:0031201 SNARE complex(GO:0031201)
0.1 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.2 GO:0005916 fascia adherens(GO:0005916)
0.1 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 4.0 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 5.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 11.9 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 21.2 GO:0060076 excitatory synapse(GO:0060076)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 3.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.6 GO:0032420 stereocilium(GO:0032420)
0.0 5.0 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 19.0 GO:0005768 endosome(GO:0005768)
0.0 4.7 GO:0005938 cell cortex(GO:0005938)
0.0 4.3 GO:0009986 cell surface(GO:0009986)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 5.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 32.1 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
8.5 101.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
4.4 35.2 GO:0032051 clathrin light chain binding(GO:0032051)
3.8 15.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.4 5.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.2 9.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.2 4.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1 3.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
1.0 5.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.8 3.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.8 2.3 GO:0005119 smoothened binding(GO:0005119)
0.7 3.7 GO:0032027 myosin light chain binding(GO:0032027)
0.7 3.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.7 5.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.6 1.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.6 3.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.6 2.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 2.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.6 2.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.6 1.7 GO:0015232 heme transporter activity(GO:0015232)
0.5 1.6 GO:0071633 dihydroceramidase activity(GO:0071633)
0.5 15.4 GO:0032183 SUMO binding(GO:0032183)
0.5 1.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.5 4.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5 14.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.5 1.9 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.5 13.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 20.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 1.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 2.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 2.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 2.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.4 8.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 17.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 5.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.4 6.2 GO:0045503 dynein light chain binding(GO:0045503)
0.4 4.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 4.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.4 1.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.4 1.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 4.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 4.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 3.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 1.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 13.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 0.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 5.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 14.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 2.9 GO:0050897 cobalt ion binding(GO:0050897)
0.3 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 5.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 4.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.3 1.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 6.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 9.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.7 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 0.5 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 1.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 2.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 2.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 17.4 GO:0016247 channel regulator activity(GO:0016247)
0.2 1.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 3.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 0.6 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.2 0.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.6 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.2 4.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 6.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 3.2 GO:0008483 transaminase activity(GO:0008483)
0.2 2.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 10.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 5.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 4.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 5.4 GO:0005112 Notch binding(GO:0005112)
0.2 1.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 3.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.9 GO:0034452 dynactin binding(GO:0034452)
0.2 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 0.5 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 4.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 37.1 GO:0008017 microtubule binding(GO:0008017)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 4.5 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 5.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 2.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 2.5 GO:0030332 cyclin binding(GO:0030332)
0.1 13.2 GO:0008565 protein transporter activity(GO:0008565)
0.1 3.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 3.2 GO:0050699 WW domain binding(GO:0050699)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 1.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 9.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 5.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 5.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 3.2 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 4.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 6.0 GO:0019955 cytokine binding(GO:0019955)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 8.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 3.0 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 6.6 GO:0008013 beta-catenin binding(GO:0008013)
0.1 12.0 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 7.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.9 GO:0043022 ribosome binding(GO:0043022)
0.1 2.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 21.1 GO:0003779 actin binding(GO:0003779)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.4 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432) phospholipase binding(GO:0043274)
0.0 0.8 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 2.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.8 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0003774 motor activity(GO:0003774)
0.0 2.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.8 GO:0016874 ligase activity(GO:0016874)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 3.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 83.9 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.5 17.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 9.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 2.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.2 8.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 4.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 1.9 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.2 7.4 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 3.6 PID_ARF6_PATHWAY Arf6 signaling events
0.2 8.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.1 PID_MYC_PATHWAY C-MYC pathway
0.1 6.0 PID_BMP_PATHWAY BMP receptor signaling
0.1 9.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 7.6 PID_LKB1_PATHWAY LKB1 signaling events
0.1 13.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 10.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.9 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.1 2.7 PID_E2F_PATHWAY E2F transcription factor network
0.1 3.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 11.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.0 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.7 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.1 PID_ARF_3PATHWAY Arf1 pathway
0.1 4.9 PID_P73PATHWAY p73 transcription factor network
0.1 2.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 3.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 4.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 3.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 2.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 87.1 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
1.6 43.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
1.1 26.7 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.6 15.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.5 13.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 6.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.5 1.9 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.4 13.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.4 6.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 6.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.4 5.1 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 4.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 3.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 2.6 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 4.2 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 2.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 18.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 7.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 9.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 3.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 15.6 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.2 4.8 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 6.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.2 3.0 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 3.0 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 2.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 4.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 6.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 5.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.2 0.6 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 6.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.8 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 4.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.0 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.7 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.6 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.8 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 4.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.1 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 4.6 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 4.0 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.5 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.8 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.7 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.9 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.1 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.3 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins