Motif ID: Rhox11

Z-value: 0.477


Transcription factors associated with Rhox11:

Gene SymbolEntrez IDGene Name
Rhox11 ENSMUSG00000051038.9 Rhox11



Activity profile for motif Rhox11.

activity profile for motif Rhox11


Sorted Z-values histogram for motif Rhox11

Sorted Z-values for motif Rhox11



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_126556935 2.325 ENSMUST00000048391.8
 Clspn
claspin
chr3_-_121171678 2.232 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
 Rwdd3




RWD domain containing 3




chr5_+_17574268 2.206 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_126556994 1.831 ENSMUST00000147675.1
 Clspn
claspin
chr5_+_21186267 1.617 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr5_+_17574726 1.613 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_+_104831572 1.604 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chrX_-_102157065 1.533 ENSMUST00000056904.2
 Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr11_+_29373618 1.531 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr10_+_58394361 1.471 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chr14_-_20496780 1.451 ENSMUST00000022353.3
 Mss51
MSS51 mitochondrial translational activator
chr10_+_58394381 1.419 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr15_+_25742314 1.418 ENSMUST00000135981.1
 Myo10
myosin X
chr7_-_28008416 1.416 ENSMUST00000180024.1
 Zfp850
zinc finger protein 850
chr15_+_8169067 1.262 ENSMUST00000110617.1
 2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr3_+_156561792 1.237 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr15_+_36179299 1.232 ENSMUST00000047348.3
 Spag1
sperm associated antigen 1
chr2_-_5862923 1.102 ENSMUST00000071016.2
 Gm13199
predicted gene 13199
chr1_-_175688353 1.002 ENSMUST00000104984.1
 Chml
choroideremia-like
chr5_+_93093428 0.901 ENSMUST00000074733.7
 Sept11
septin 11
chr13_-_3611064 0.881 ENSMUST00000096069.3
 BC016423
cDNA sequence BC016423
chr13_+_49653297 0.836 ENSMUST00000021824.7
 Nol8
nucleolar protein 8
chr11_-_100355383 0.739 ENSMUST00000146878.2
 Hap1
huntingtin-associated protein 1
chr15_+_41789495 0.647 ENSMUST00000090095.5
ENSMUST00000022918.7
 Oxr1

oxidation resistance 1

chr8_-_105827190 0.639 ENSMUST00000041400.5
 Ranbp10
RAN binding protein 10
chr7_-_46795881 0.625 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr9_-_20521375 0.620 ENSMUST00000068296.7
ENSMUST00000174462.1
 Zfp266

zinc finger protein 266

chr12_-_99883429 0.588 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr6_-_34977999 0.554 ENSMUST00000044387.7
 2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr8_-_81014866 0.534 ENSMUST00000042724.6
 Usp38
ubiquitin specific peptidase 38
chr8_+_3353415 0.517 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chrX_-_111536325 0.515 ENSMUST00000156639.1
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr19_-_60581013 0.507 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
 Cacul1


CDK2 associated, cullin domain 1


chr3_+_127791374 0.503 ENSMUST00000171621.1
 Tifa
TRAF-interacting protein with forkhead-associated domain
chr7_-_46795661 0.481 ENSMUST00000123725.1
 Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr16_+_29579347 0.480 ENSMUST00000038867.6
ENSMUST00000161186.1
 Opa1

optic atrophy 1

chr17_-_47016956 0.478 ENSMUST00000165525.1
 Gm16494
predicted gene 16494
chr5_+_138187485 0.473 ENSMUST00000110934.2
 Cnpy4
canopy 4 homolog (zebrafish)
chr11_-_5381734 0.471 ENSMUST00000172492.1
 Znrf3
zinc and ring finger 3
chr5_+_111733924 0.465 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr16_+_29579331 0.457 ENSMUST00000160597.1
 Opa1
optic atrophy 1
chr13_+_47043499 0.452 ENSMUST00000037025.8
ENSMUST00000143868.1
 Kdm1b

lysine (K)-specific demethylase 1B

chr13_+_95325195 0.442 ENSMUST00000045909.7
 Zbed3
zinc finger, BED domain containing 3
chr15_+_7129557 0.429 ENSMUST00000067190.5
ENSMUST00000164529.1
 Lifr

leukemia inhibitory factor receptor

chr5_+_143933059 0.388 ENSMUST00000166847.1
 Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr2_-_131352857 0.383 ENSMUST00000059372.4
 Rnf24
ring finger protein 24
chr14_-_46822232 0.369 ENSMUST00000111817.1
ENSMUST00000079314.5
 Gmfb

glia maturation factor, beta

chr2_-_150362708 0.368 ENSMUST00000051153.5
 3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr17_+_79614900 0.365 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr9_-_8134294 0.355 ENSMUST00000037397.6
 AK129341
cDNA sequence AK129341
chrX_+_105079735 0.341 ENSMUST00000033577.4
 Pbdc1
polysaccharide biosynthesis domain containing 1
chr1_-_169969143 0.325 ENSMUST00000027989.6
ENSMUST00000111353.3
 Hsd17b7

hydroxysteroid (17-beta) dehydrogenase 7

chr8_+_94386438 0.296 ENSMUST00000161576.1
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_-_16378231 0.289 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr11_-_102082464 0.280 ENSMUST00000100398.4
 Mpp2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr5_+_121220191 0.268 ENSMUST00000119892.2
ENSMUST00000042614.6
 Gm15800

predicted gene 15800

chrX_+_105079761 0.266 ENSMUST00000119477.1
 Pbdc1
polysaccharide biosynthesis domain containing 1
chr6_-_106800051 0.226 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
 Crbn


cereblon


chr6_+_54264839 0.207 ENSMUST00000146114.1
 Chn2
chimerin (chimaerin) 2
chr9_+_50768228 0.182 ENSMUST00000042391.6
 Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr6_+_128662379 0.180 ENSMUST00000032518.4
 Clec2h
C-type lectin domain family 2, member h
chr11_-_97700327 0.166 ENSMUST00000018681.7
 Pcgf2
polycomb group ring finger 2
chr11_+_70639118 0.164 ENSMUST00000055184.6
ENSMUST00000108551.2
 Gp1ba

glycoprotein 1b, alpha polypeptide

chr19_-_8818924 0.161 ENSMUST00000153281.1
 Ttc9c
tetratricopeptide repeat domain 9C
chr8_+_94386486 0.161 ENSMUST00000034220.7
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr18_+_6765171 0.158 ENSMUST00000097680.5
 Rab18
RAB18, member RAS oncogene family
chr2_+_178118975 0.137 ENSMUST00000108917.1
 Phactr3
phosphatase and actin regulator 3
chr9_-_107289847 0.114 ENSMUST00000035194.2
 Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr7_+_46796088 0.113 ENSMUST00000006774.4
ENSMUST00000165031.1
 Gtf2h1

general transcription factor II H, polypeptide 1

chr9_-_67043709 0.097 ENSMUST00000113689.1
ENSMUST00000113684.1
 Tpm1

tropomyosin 1, alpha

chr1_+_169969409 0.093 ENSMUST00000180638.1
 3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr7_-_30664986 0.090 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr9_-_44713196 0.070 ENSMUST00000144251.1
ENSMUST00000156918.1
 Phldb1

pleckstrin homology-like domain, family B, member 1

chr10_-_59951753 0.059 ENSMUST00000020308.3
 Ddit4
DNA-damage-inducible transcript 4
chr10_+_21295979 0.048 ENSMUST00000020153.8
ENSMUST00000092674.6
 Hbs1l

Hbs1-like (S. cerevisiae)

chr17_+_40811089 0.035 ENSMUST00000024721.7
 Rhag
Rhesus blood group-associated A glycoprotein
chr13_+_40886758 0.014 ENSMUST00000069958.7
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.6 3.8 GO:0003350 pulmonary myocardium development(GO:0003350)
0.6 2.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 4.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.9 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.2 1.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.7 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 1.0 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.5 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 1.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.2 GO:0007338 single fertilization(GO:0007338)
0.0 0.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 1.1 GO:0043473 pigmentation(GO:0043473)
0.0 1.2 GO:0007631 feeding behavior(GO:0007631)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 1.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 3.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 0.9 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 1.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 2.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 3.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1