Motif ID: Rorc_Nr1d1

Z-value: 0.576

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rorcmm10_v2_chr3_+_94372794_943728720.371.8e-02Click!
Nr1d1mm10_v2_chr11_-_98775333_98775354-0.279.3e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 3.080 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr11_-_84069179 2.509 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr1_-_14310198 2.237 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr12_-_34528844 2.177 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr3_-_89764581 1.935 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chrX_+_103422010 1.743 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr13_+_6548154 1.456 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr5_+_64970069 1.358 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr11_+_94327984 1.313 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr1_+_6734827 1.288 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr5_+_64803513 1.208 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr11_+_94328242 1.191 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr15_-_50882806 1.083 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr6_+_61180313 1.029 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr3_-_10208569 0.979 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr7_+_45705088 0.911 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr3_+_79884576 0.770 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr6_-_88874045 0.742 ENSMUST00000038409.5
Podxl2
podocalyxin-like 2
chr3_-_101307079 0.741 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr3_+_79884496 0.731 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr1_-_180193475 0.694 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chr6_-_93913678 0.680 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr7_-_134232125 0.663 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr10_+_57784859 0.641 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr11_-_100527896 0.637 ENSMUST00000107389.1
ENSMUST00000007131.9
Acly

ATP citrate lyase

chr3_-_84304762 0.630 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr2_+_155751117 0.612 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr11_-_100527862 0.610 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr14_+_73142490 0.609 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2


chr4_+_98546919 0.595 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr7_-_122021143 0.533 ENSMUST00000033160.8
Gga2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr4_+_11579647 0.525 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr16_-_20730544 0.519 ENSMUST00000076422.5
Thpo
thrombopoietin
chr6_-_42520325 0.498 ENSMUST00000104977.2
Gm4877
predicted gene 4877
chr7_-_134232005 0.489 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr17_-_51810866 0.472 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr16_-_37384915 0.460 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr8_-_85080679 0.458 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83
chr2_-_5862923 0.456 ENSMUST00000071016.2
Gm13199
predicted gene 13199
chr2_+_61593077 0.439 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr8_+_119862239 0.435 ENSMUST00000034287.8
Klhl36
kelch-like 36
chrX_-_16911774 0.427 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr6_+_29361410 0.423 ENSMUST00000156163.1
Calu
calumenin
chr14_-_54577578 0.417 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr2_+_61593125 0.414 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr4_-_55532453 0.413 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr16_-_37384940 0.410 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr9_+_46012810 0.409 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr11_+_98348404 0.401 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_+_143739551 0.394 ENSMUST00000050491.9
Glrx2
glutaredoxin 2 (thioltransferase)
chr8_-_85080652 0.393 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr5_-_115484297 0.374 ENSMUST00000112067.1
Sirt4
sirtuin 4
chr14_-_98169542 0.371 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr2_+_91710852 0.361 ENSMUST00000128140.1
ENSMUST00000140183.1
Harbi1

harbinger transposase derived 1

chr7_-_126922887 0.360 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
Tmem219


transmembrane protein 219


chr6_+_65778988 0.347 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
Prdm5



PR domain containing 5



chr7_+_114768736 0.332 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr9_-_101034857 0.332 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr11_+_95712673 0.326 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr7_+_127211608 0.321 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_-_101034892 0.317 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr12_-_100159601 0.301 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chrX_+_70385870 0.287 ENSMUST00000053981.5
1110012L19Rik
RIKEN cDNA 1110012L19 gene
chr7_+_46033698 0.284 ENSMUST00000033121.6
Nomo1
nodal modulator 1
chr11_-_98329641 0.282 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr17_+_45686322 0.279 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr7_+_113207465 0.272 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr2_+_91710900 0.244 ENSMUST00000142692.1
ENSMUST00000090608.5
Harbi1

harbinger transposase derived 1

chrX_+_42151002 0.242 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr12_-_84876479 0.216 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr6_-_124712131 0.215 ENSMUST00000004379.5
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr12_+_116047713 0.213 ENSMUST00000073551.5
ENSMUST00000183125.1
Zfp386

zinc finger protein 386 (Kruppel-like)

chr11_+_68901538 0.212 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26



ribosomal protein L26



chr4_+_3940747 0.204 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_-_170427828 0.203 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr17_-_24886304 0.202 ENSMUST00000044252.5
Nubp2
nucleotide binding protein 2
chr16_+_22009471 0.200 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr11_+_3650253 0.189 ENSMUST00000096441.3
Morc2a
microrchidia 2A
chr15_+_89253035 0.186 ENSMUST00000088788.3
Ppp6r2
protein phosphatase 6, regulatory subunit 2
chr3_-_107931817 0.180 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chr7_-_142661305 0.149 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr17_-_45686214 0.145 ENSMUST00000113523.2
Tmem63b
transmembrane protein 63b
chr3_+_90603767 0.145 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr2_-_91710519 0.145 ENSMUST00000028678.8
ENSMUST00000076803.5
Atg13

autophagy related 13

chr7_-_142661858 0.144 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr9_+_65460926 0.144 ENSMUST00000034955.6
Spg21
spastic paraplegia 21 homolog (human)
chr3_-_107931579 0.135 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
Gstm7



glutathione S-transferase, mu 7



chr17_-_45686899 0.126 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr1_+_86703788 0.123 ENSMUST00000168237.1
ENSMUST00000065694.6
Dis3l2

DIS3 mitotic control homolog (S. cerevisiae)-like 2

chr11_-_59290746 0.119 ENSMUST00000010044.7
Wnt3a
wingless-related MMTV integration site 3A
chr3_-_103809278 0.118 ENSMUST00000063502.6
ENSMUST00000106832.1
ENSMUST00000106834.1
ENSMUST00000029435.8
Dclre1b



DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)



chr11_-_115628260 0.114 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr3_-_153944425 0.113 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr11_+_70030023 0.105 ENSMUST00000143920.2
Dlg4
discs, large homolog 4 (Drosophila)
chr17_-_46031813 0.105 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr17_+_24896488 0.104 ENSMUST00000024978.6
Nme3
NME/NM23 nucleoside diphosphate kinase 3
chr9_+_77754526 0.102 ENSMUST00000034905.8
Gclc
glutamate-cysteine ligase, catalytic subunit
chr15_+_81872309 0.095 ENSMUST00000023116.6
Aco2
aconitase 2, mitochondrial
chr12_-_24493656 0.090 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr1_+_160195215 0.089 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14

chr17_-_34628005 0.087 ENSMUST00000166040.2
Ppt2
palmitoyl-protein thioesterase 2
chr4_+_94739276 0.080 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr14_-_54864055 0.079 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr15_-_98662858 0.073 ENSMUST00000162384.1
ENSMUST00000003450.8
Ddx23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr17_+_33638056 0.072 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr11_+_87581041 0.062 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
Sept4


septin 4


chr1_-_191907527 0.050 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr7_-_126585775 0.049 ENSMUST00000084589.4
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr17_+_37046555 0.045 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_-_30559600 0.044 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr9_-_54647199 0.042 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr6_-_30896735 0.041 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
Copg2


coatomer protein complex, subunit gamma 2


chr5_-_123141067 0.040 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr3_+_53463666 0.035 ENSMUST00000058577.4
Proser1
proline and serine rich 1
chr7_-_126625676 0.029 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr15_-_10485385 0.027 ENSMUST00000168690.1
Brix1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr5_-_65335564 0.022 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr6_-_97205549 0.020 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3

ubiquitin-like modifier activating enzyme 3

chr12_+_100110148 0.011 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr7_+_13398115 0.011 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr11_-_116199040 0.008 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_116198701 0.006 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_+_114890041 0.003 ENSMUST00000106582.2
ENSMUST00000045151.5
Cd300a

CD300A antigen

chr11_+_3649759 0.000 ENSMUST00000140242.1
Morc2a
microrchidia 2A

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.4 2.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 2.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.5 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 2.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 1.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.0 0.6 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.1 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 0.4 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 2.3 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0016246 RNA interference(GO:0016246)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.9 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587) nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.4 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 2.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 3.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:0019841 retinol binding(GO:0019841)
0.2 0.6 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.2 0.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 2.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 2.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.0 PID_AP1_PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions