Motif ID: Runx2_Bcl11a

Z-value: 1.874

Transcription factors associated with Runx2_Bcl11a:

Gene SymbolEntrez IDGene Name
Bcl11a ENSMUSG00000000861.9 Bcl11a
Runx2 ENSMUSG00000039153.10 Runx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl11amm10_v2_chr11_+_24078173_24078219-0.571.1e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Runx2_Bcl11a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103827922 33.047 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr11_-_83649349 15.226 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr19_+_3935186 12.722 ENSMUST00000162708.1
ENSMUST00000165711.1
Unc93b1

unc-93 homolog B1 (C. elegans)

chr4_+_144892813 11.072 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr3_-_87263518 10.564 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr4_-_136892867 10.151 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr15_-_66801577 9.910 ENSMUST00000168589.1
Sla
src-like adaptor
chr5_-_77408034 9.637 ENSMUST00000163898.1
ENSMUST00000046746.6
Igfbp7

insulin-like growth factor binding protein 7

chr1_+_58210397 8.334 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr15_+_3270767 7.455 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr3_-_87263703 7.420 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr4_+_144893127 7.213 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_172297989 6.462 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr15_-_37459327 6.300 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr5_+_90772435 6.095 ENSMUST00000031320.6
Pf4
platelet factor 4
chr11_+_101246960 5.980 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr1_-_140183404 5.941 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr13_-_37050237 5.832 ENSMUST00000164727.1
F13a1
coagulation factor XIII, A1 subunit
chr11_+_82045705 5.653 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr1_+_169655493 5.481 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr8_-_11008458 5.291 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr19_+_47854970 5.219 ENSMUST00000026050.7
Gsto1
glutathione S-transferase omega 1
chr11_-_106388066 4.964 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr5_+_37047464 4.914 ENSMUST00000137019.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr1_-_169747634 4.855 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr10_-_62507737 4.827 ENSMUST00000020271.6
Srgn
serglycin
chr1_+_45311538 4.800 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr11_+_105975204 4.783 ENSMUST00000001964.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chrX_-_48034842 4.739 ENSMUST00000039026.7
Apln
apelin
chr15_-_75567176 4.532 ENSMUST00000156032.1
ENSMUST00000127095.1
Ly6h

lymphocyte antigen 6 complex, locus H

chr8_+_104170513 4.515 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr11_+_3330781 4.484 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr4_+_144893077 4.483 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_48049080 4.467 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr10_-_62379852 4.385 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr9_-_103219823 4.287 ENSMUST00000168142.1
Trf
transferrin
chr19_-_20390944 4.257 ENSMUST00000025561.7
Anxa1
annexin A1
chr3_+_90514435 4.133 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr15_-_76660108 4.009 ENSMUST00000066677.8
ENSMUST00000177359.1
Cyhr1

cysteine and histidine rich 1

chr6_+_17491216 3.809 ENSMUST00000080469.5
Met
met proto-oncogene
chr5_+_37050854 3.708 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr16_+_91391721 3.662 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr11_-_101785252 3.617 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr4_+_42114817 3.521 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr18_+_37496997 3.428 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr1_-_140183283 3.420 ENSMUST00000111977.1
Cfh
complement component factor h
chr11_-_100414829 3.373 ENSMUST00000066489.6
Leprel4
leprecan-like 4
chr4_-_14621805 3.321 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr5_-_44799643 3.245 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr7_-_142661858 3.226 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr3_-_86142684 3.211 ENSMUST00000029722.6
Rps3a1
ribosomal protein S3A1
chr13_+_76579670 3.200 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr4_+_41903610 3.169 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr13_-_84064772 3.137 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr5_+_104435112 3.108 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
Spp1





secreted phosphoprotein 1





chr5_-_146585239 3.050 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr14_-_66280949 3.046 ENSMUST00000111121.1
ENSMUST00000022622.7
ENSMUST00000089250.2
Ptk2b


PTK2 protein tyrosine kinase 2 beta


chr19_-_4305955 3.027 ENSMUST00000025791.5
Adrbk1
adrenergic receptor kinase, beta 1
chr11_-_98329641 2.968 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr10_+_42502030 2.954 ENSMUST00000105500.1
ENSMUST00000019939.5
Snx3

sorting nexin 3

chr5_+_24364804 2.954 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr15_-_37458523 2.945 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr11_+_96849863 2.928 ENSMUST00000018816.7
Copz2
coatomer protein complex, subunit zeta 2
chr1_-_72874877 2.924 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr5_-_105139539 2.922 ENSMUST00000100961.4
ENSMUST00000031235.6
ENSMUST00000100962.3
Gbp9
Gbp8
Gbp4
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr11_+_3330401 2.899 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_+_78322965 2.897 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr4_+_127172866 2.837 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr19_-_4125837 2.836 ENSMUST00000121402.1
ENSMUST00000117831.1
Aip

aryl-hydrocarbon receptor-interacting protein

chrX_+_99003224 2.824 ENSMUST00000149999.1
Stard8
START domain containing 8
chr19_-_5273080 2.821 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr4_+_42255767 2.812 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr14_-_51913393 2.811 ENSMUST00000004673.7
ENSMUST00000111632.3
Ndrg2

N-myc downstream regulated gene 2

chr12_+_36314160 2.803 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr11_-_76577701 2.789 ENSMUST00000176179.1
Abr
active BCR-related gene
chr9_-_77251829 2.787 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr4_-_138396438 2.783 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr3_-_88000350 2.768 ENSMUST00000090971.5
Bcan
brevican
chr2_-_168741752 2.759 ENSMUST00000029060.4
Atp9a
ATPase, class II, type 9A
chr4_+_152199805 2.741 ENSMUST00000105652.2
Acot7
acyl-CoA thioesterase 7
chr4_+_128058962 2.704 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr2_+_70562007 2.682 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr11_-_69920892 2.600 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr7_-_90129339 2.552 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr17_-_35175995 2.545 ENSMUST00000173324.1
Aif1
allograft inflammatory factor 1
chr3_-_90514250 2.523 ENSMUST00000107340.1
ENSMUST00000060738.8
S100a1

S100 calcium binding protein A1

chr13_+_16014457 2.505 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr19_-_57118897 2.476 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr18_+_37355271 2.474 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr11_+_82035569 2.466 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr7_+_49246812 2.465 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr7_-_142666816 2.388 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr11_+_120721452 2.386 ENSMUST00000018156.5
Rac3
RAS-related C3 botulinum substrate 3
chr11_+_83662579 2.374 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chr4_-_46991842 2.352 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_-_136260873 2.351 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chrX_-_140543177 2.344 ENSMUST00000055738.5
Tsc22d3
TSC22 domain family, member 3
chr5_-_124187150 2.298 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr19_-_57197496 2.288 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr2_+_121357714 2.277 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr19_+_6400523 2.269 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr19_-_57197377 2.255 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr5_+_89027959 2.231 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr2_-_150255591 2.222 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr11_-_110168073 2.212 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_-_14621669 2.207 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr2_-_156992021 2.181 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
Ndrg3


N-myc downstream regulated gene 3


chr3_-_57294880 2.174 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chrX_-_57338598 2.172 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr19_-_57197435 2.172 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr4_+_126148457 2.153 ENSMUST00000106150.2
Eva1b
eva-1 homolog B (C. elegans)
chr17_+_35236556 2.146 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr9_+_90054529 2.131 ENSMUST00000143172.1
Ctsh
cathepsin H
chr7_-_78577771 2.125 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr9_-_77251871 2.109 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr6_+_17749170 2.103 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr7_+_19176416 2.067 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr4_-_127970951 2.061 ENSMUST00000030614.2
CK137956
cDNA sequence CK137956
chr5_-_125294107 2.051 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr7_-_141010759 2.040 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chrX_-_101268218 2.027 ENSMUST00000033664.7
Il2rg
interleukin 2 receptor, gamma chain
chr7_-_100863373 2.025 ENSMUST00000142885.1
ENSMUST00000008462.3
Relt

RELT tumor necrosis factor receptor

chr1_+_172499948 1.998 ENSMUST00000111230.1
Tagln2
transgelin 2
chr18_+_61105844 1.997 ENSMUST00000115268.3
Csf1r
colony stimulating factor 1 receptor
chr8_+_25518783 1.974 ENSMUST00000084027.5
ENSMUST00000117179.2
Fgfr1

fibroblast growth factor receptor 1

chr13_-_97198351 1.973 ENSMUST00000022169.7
Hexb
hexosaminidase B
chr2_+_156547570 1.968 ENSMUST00000109570.1
ENSMUST00000029158.3
ENSMUST00000150212.1
ENSMUST00000126250.1
Aar2



AAR2 splicing factor homolog (S. cerevisiae)



chr4_-_134254076 1.964 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr3_+_96181151 1.961 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr11_-_103344651 1.942 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr5_+_34549595 1.931 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr4_+_102254739 1.930 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr17_-_45592569 1.890 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr17_+_24720063 1.877 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr15_+_10952332 1.872 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr7_-_128596278 1.862 ENSMUST00000179317.1
Gm7258
predicted gene 7258
chr18_+_37518341 1.856 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr2_+_70562147 1.835 ENSMUST00000148210.1
Gad1
glutamate decarboxylase 1
chr4_-_14621494 1.815 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr3_+_86070915 1.802 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr7_+_101361997 1.789 ENSMUST00000133423.1
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_35235755 1.770 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr1_-_168432270 1.762 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr8_+_25518757 1.742 ENSMUST00000178276.1
ENSMUST00000179592.1
Fgfr1

fibroblast growth factor receptor 1

chr6_+_94500313 1.739 ENSMUST00000061118.8
Slc25a26
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr10_+_43579161 1.725 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr7_-_73375722 1.716 ENSMUST00000181299.1
A730056A06Rik
RIKEN cDNA A730056A06 gene
chr2_+_4300462 1.714 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr2_-_132111440 1.681 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr9_-_111057235 1.679 ENSMUST00000111888.1
Ccrl2
chemokine (C-C motif) receptor-like 2
chr11_-_116654245 1.675 ENSMUST00000021166.5
Cygb
cytoglobin
chr15_-_79285502 1.667 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr19_-_10880370 1.666 ENSMUST00000133303.1
Tmem109
transmembrane protein 109
chr11_+_98753512 1.661 ENSMUST00000124072.1
Thra
thyroid hormone receptor alpha
chr19_-_4306214 1.660 ENSMUST00000171123.1
ENSMUST00000088737.4
Adrbk1

adrenergic receptor kinase, beta 1

chr10_+_61171954 1.651 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
Tbata


thymus, brain and testes associated


chr15_-_79834323 1.632 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr10_+_42502197 1.625 ENSMUST00000105499.1
Snx3
sorting nexin 3
chr8_+_27260327 1.624 ENSMUST00000033880.5
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr17_-_47691403 1.602 ENSMUST00000113299.1
ENSMUST00000152214.1
Gm21981
Prickle4
predicted gene 21981
prickle homolog 4 (Drosophila)
chr7_+_3617357 1.593 ENSMUST00000076657.4
ENSMUST00000108644.1
Ndufa3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3

chr3_-_142169311 1.590 ENSMUST00000106230.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr5_+_122643878 1.578 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr16_-_97922582 1.576 ENSMUST00000170757.1
C2cd2
C2 calcium-dependent domain containing 2
chr11_+_116030304 1.570 ENSMUST00000021116.5
ENSMUST00000106452.1
Unk

unkempt homolog (Drosophila)

chr14_+_31641051 1.553 ENSMUST00000090147.6
Btd
biotinidase
chr10_-_81291227 1.550 ENSMUST00000045744.6
Tjp3
tight junction protein 3
chr16_+_95702044 1.536 ENSMUST00000023612.8
Ets2
E26 avian leukemia oncogene 2, 3' domain
chr19_-_6235804 1.523 ENSMUST00000025695.9
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr7_-_127824469 1.520 ENSMUST00000106267.3
Stx1b
syntaxin 1B
chr13_-_54611274 1.512 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr1_-_168431695 1.509 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr5_+_89028035 1.507 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr13_+_63014934 1.507 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr19_+_55253369 1.506 ENSMUST00000043150.4
Acsl5
acyl-CoA synthetase long-chain family member 5
chr10_+_79689020 1.506 ENSMUST00000020549.3
Gzmm
granzyme M (lymphocyte met-ase 1)
chr1_+_165769392 1.497 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chr7_-_27181149 1.488 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr4_-_42773993 1.482 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr3_-_108017877 1.458 ENSMUST00000004140.4
Gstm1
glutathione S-transferase, mu 1
chr3_-_85746266 1.450 ENSMUST00000118408.1
Fam160a1
family with sequence similarity 160, member A1
chr15_+_92597104 1.436 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr7_+_128246812 1.434 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr11_-_115001880 1.431 ENSMUST00000092464.3
AF251705
cDNA sequence AF251705
chr4_+_137707458 1.430 ENSMUST00000097837.4
Rap1gap
Rap1 GTPase-activating protein
chr17_-_45592485 1.420 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr6_+_55836878 1.411 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr6_-_119388671 1.391 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr1_-_120074023 1.385 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr4_+_102589687 1.383 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr11_-_110095937 1.380 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr11_-_79530569 1.367 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr11_-_52282564 1.367 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr13_-_25270076 1.366 ENSMUST00000057866.6
Nrsn1
neurensin 1
chr4_+_136284658 1.356 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr11_-_69920581 1.355 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr4_+_115057683 1.352 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr2_-_26021532 1.349 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr17_+_56717759 1.335 ENSMUST00000002452.6
Ndufa11
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr13_-_92483996 1.326 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0046110 xanthine metabolic process(GO:0046110)
2.5 12.7 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
2.2 6.5 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
2.2 6.5 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
2.1 22.8 GO:0042572 retinol metabolic process(GO:0042572)
1.9 5.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.9 5.8 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
1.9 17.2 GO:0043615 astrocyte cell migration(GO:0043615)
1.6 4.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.6 4.8 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.6 4.7 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
1.6 9.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.5 4.5 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
1.5 4.5 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.5 10.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
1.4 4.3 GO:0036292 positive regulation of prostaglandin biosynthetic process(GO:0031394) DNA rewinding(GO:0036292) neutrophil clearance(GO:0097350) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.4 6.9 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
1.2 3.7 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
1.2 6.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
1.2 2.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.1 3.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.0 7.3 GO:0019532 oxalate transport(GO:0019532)
1.0 3.0 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
1.0 6.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.0 3.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.0 6.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.0 4.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9 2.8 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.9 2.8 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.9 6.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.8 2.4 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.8 3.1 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.7 2.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.7 2.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.7 2.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 4.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.7 0.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.7 2.7 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.7 2.7 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.7 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.7 4.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.7 3.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.6 4.5 GO:0015862 uridine transport(GO:0015862)
0.6 4.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.6 4.4 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6 2.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.6 3.6 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.6 2.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.6 6.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.6 1.7 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.6 2.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.6 1.7 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.5 4.3 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.5 2.1 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.5 2.6 GO:0051182 coenzyme transport(GO:0051182)
0.5 2.5 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.5 1.0 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.5 1.9 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.5 2.3 GO:0001705 ectoderm formation(GO:0001705)
0.4 1.3 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.4 0.9 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.4 2.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 3.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 2.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 3.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 1.6 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 3.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.4 1.2 GO:0050975 sensory perception of touch(GO:0050975)
0.4 0.8 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.4 1.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.4 1.5 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.4 3.7 GO:0015701 bicarbonate transport(GO:0015701)
0.4 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 1.5 GO:0060431 primary lung bud formation(GO:0060431)
0.4 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 1.8 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.3 2.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 1.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.3 1.7 GO:0015671 oxygen transport(GO:0015671)
0.3 2.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.3 1.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3 1.3 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838)
0.3 1.8 GO:0002606 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.3 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 1.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.3 0.9 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.3 2.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 2.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 3.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.3 1.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 2.4 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.3 1.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.3 1.1 GO:0007412 axon target recognition(GO:0007412)
0.3 1.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 2.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 1.0 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.5 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.2 1.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 1.6 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 2.5 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.2 10.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 1.3 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.2 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 1.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 1.6 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.0 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 0.6 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2 0.6 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 0.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 0.7 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 1.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 3.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 1.4 GO:0061042 vascular wound healing(GO:0061042)
0.2 0.5 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.2 3.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 2.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 0.6 GO:0031017 exocrine pancreas development(GO:0031017)
0.2 1.3 GO:0036376 sodium ion export from cell(GO:0036376)
0.2 1.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.2 0.9 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 1.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2 1.5 GO:0019835 cytolysis(GO:0019835)
0.2 1.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 1.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 1.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 9.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 3.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.7 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 8.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 3.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 1.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 3.3 GO:0030325 adrenal gland development(GO:0030325)
0.1 2.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 2.2 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 2.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.5 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.1 0.6 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 2.7 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.1 0.7 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.2 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.1 0.9 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.1 1.2 GO:0002347 response to tumor cell(GO:0002347)
0.1 1.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) positive regulation of mitochondrial DNA metabolic process(GO:1901860) stress-induced mitochondrial fusion(GO:1990046)
0.1 0.9 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 2.5 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.7 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.8 GO:0021612 facial nerve structural organization(GO:0021612)
0.1 1.6 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 6.4 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.1 0.3 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 4.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.6 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 1.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.9 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 3.7 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.1 0.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.6 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.4 GO:0015705 iodide transport(GO:0015705)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.8 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.9 GO:0051923 sulfation(GO:0051923)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.8 GO:0043144 snoRNA processing(GO:0043144)
0.1 0.2 GO:1903750 negative regulation of cellular respiration(GO:1901856) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.5 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.1 1.4 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.1 0.6 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 0.3 GO:0015825 L-serine transport(GO:0015825)
0.1 2.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.4 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.1 1.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.2 GO:0015744 succinate transport(GO:0015744)
0.1 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.9 GO:0045056 transcytosis(GO:0045056)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.2 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 1.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 1.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 1.1 GO:0030501 positive regulation of bone mineralization(GO:0030501)
0.0 1.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.5 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 2.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.8 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.6 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.3 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 1.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.7 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.9 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.0 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.1 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 1.3 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.2 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0048597 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 0.4 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.0 0.1 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.0 0.1 GO:0015819 lysine transport(GO:0015819)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304) histone H3-K27 demethylation(GO:0071557)
0.0 0.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.1 GO:0070627 ferrous iron import(GO:0070627)
0.0 4.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0014741 negative regulation of muscle hypertrophy(GO:0014741)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:0021766 hippocampus development(GO:0021766)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.4 GO:0015844 monoamine transport(GO:0015844)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.3 GO:0045214 sarcomere organization(GO:0045214)
0.0 1.4 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.0 GO:0044828 negative regulation by host of viral process(GO:0044793) negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 33.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.7 17.3 GO:0032009 early phagosome(GO:0032009)
1.2 6.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.1 9.1 GO:0042629 mast cell granule(GO:0042629)
1.1 7.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.1 3.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.9 2.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.8 2.5 GO:0043512 inhibin A complex(GO:0043512)
0.8 9.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.8 2.5 GO:0044299 C-fiber(GO:0044299)
0.7 2.2 GO:0033193 Lsd1/2 complex(GO:0033193)
0.7 2.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.7 3.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.6 2.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.6 5.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 4.3 GO:0097433 dense body(GO:0097433)
0.4 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 1.2 GO:0045098 type III intermediate filament(GO:0045098)
0.4 1.1 GO:0051233 spindle midzone(GO:0051233)
0.4 4.0 GO:0005642 annulate lamellae(GO:0005642)
0.4 0.4 GO:0070820 tertiary granule(GO:0070820)
0.3 5.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 2.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 3.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.3 2.2 GO:0005638 lamin filament(GO:0005638)
0.3 5.5 GO:0097225 sperm midpiece(GO:0097225)
0.3 4.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 24.0 GO:0072562 blood microparticle(GO:0072562)
0.3 1.1 GO:0014802 terminal cisterna(GO:0014802)
0.3 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 2.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 3.9 GO:0097228 sperm principal piece(GO:0097228)
0.2 1.5 GO:0071439 clathrin complex(GO:0071439)
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.7 GO:0034457 Mpp10 complex(GO:0034457)
0.2 2.1 GO:0034709 methylosome(GO:0034709)
0.2 10.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 2.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 2.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 1.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 2.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 5.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.2 GO:0042581 specific granule(GO:0042581)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.6 GO:1990462 omegasome(GO:1990462)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 2.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.6 GO:0097513 myosin II filament(GO:0097513)
0.1 1.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.6 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.1 4.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.3 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 2.2 GO:0031430 M band(GO:0031430)
0.1 7.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.1 GO:0043293 apoptosome(GO:0043293)
0.1 16.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:0031143 pseudopodium(GO:0031143)
0.1 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.8 GO:0005901 caveola(GO:0005901)
0.1 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 2.3 GO:0005911 cell-cell junction(GO:0005911)
0.1 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.8 GO:0031941 filamentous actin(GO:0031941)
0.1 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 38.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 7.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 2.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.8 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011)
0.0 1.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.9 GO:0031975 envelope(GO:0031975)
0.0 0.2 GO:0030677 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.4 GO:0043235 receptor complex(GO:0043235)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.8 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.0 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 3.6 GO:0005769 early endosome(GO:0005769)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 5.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 33.0 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
3.3 22.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
2.5 7.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
2.3 9.4 GO:0001851 complement component C3b binding(GO:0001851)
2.1 8.3 GO:0030151 molybdenum ion binding(GO:0030151)
2.0 8.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.7 5.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.5 5.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.2 6.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.2 6.0 GO:0097643 amylin receptor activity(GO:0097643)
1.2 4.8 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
1.1 4.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
1.0 4.1 GO:0050786 RAGE receptor binding(GO:0050786)
1.0 3.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.0 23.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
1.0 3.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.9 2.8 GO:0036004 GAF domain binding(GO:0036004)
0.9 3.6 GO:0004111 creatine kinase activity(GO:0004111)
0.8 2.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.8 7.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.8 12.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.7 3.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.7 7.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.6 4.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 1.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.6 4.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.6 3.7 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.6 2.4 GO:0050436 microfibril binding(GO:0050436)
0.6 3.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 3.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 1.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.6 1.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.6 1.7 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.5 9.7 GO:0050811 GABA receptor binding(GO:0050811)
0.5 11.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 2.1 GO:0030984 kininogen binding(GO:0030984)
0.5 4.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.3 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4 2.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 3.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 2.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 2.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 3.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 5.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 1.6 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 2.8 GO:0098821 BMP receptor activity(GO:0098821)
0.4 2.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.4 1.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 2.3 GO:0043426 MRF binding(GO:0043426)
0.4 4.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 3.2 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.4 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.3 0.3 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.3 1.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 1.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 1.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3 1.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 1.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 0.9 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.3 0.9 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.3 0.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 1.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.9 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 5.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 1.7 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.3 4.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 7.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 0.8 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.3 6.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 1.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.3 1.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 4.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 4.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.3 1.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 2.5 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.2 GO:0070404 NADH binding(GO:0070404)
0.2 2.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 0.7 GO:0030519 snoRNP binding(GO:0030519)
0.2 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 3.3 GO:0070411 I-SMAD binding(GO:0070411)
0.2 0.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 3.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 2.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 2.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 1.0 GO:0034235 GPI anchor binding(GO:0034235)
0.2 1.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 1.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 0.5 GO:0005118 sevenless binding(GO:0005118)
0.2 2.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 6.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 5.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.2 2.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.2 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 1.5 GO:0016151 nickel cation binding(GO:0016151)
0.2 1.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 4.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.7 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.1 GO:0080084 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.1 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.8 GO:0097001 ceramide binding(GO:0097001)
0.1 0.9 GO:0050897 cobalt ion binding(GO:0050897)
0.1 2.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.3 GO:0019956 chemokine binding(GO:0019956)
0.1 1.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 4.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 5.2 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.2 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.3 GO:0030172 troponin C binding(GO:0030172)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 3.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 6.8 GO:0008083 growth factor activity(GO:0008083)
0.1 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.7 GO:0050733 pre-mRNA 3'-splice site binding(GO:0030628) RS domain binding(GO:0050733)
0.1 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.8 GO:0031005 filamin binding(GO:0031005)
0.1 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 2.5 GO:0019838 growth factor binding(GO:0019838)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:1990405 protein antigen binding(GO:1990405)
0.1 2.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528) alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 3.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 4.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 2.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 2.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 3.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 8.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.3 9.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.3 52.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 13.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 4.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.2 3.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 10.1 PID_ENDOTHELIN_PATHWAY Endothelins
0.2 5.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.2 1.8 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 7.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 4.6 PID_SHP2_PATHWAY SHP2 signaling
0.1 0.5 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.8 PID_FGF_PATHWAY FGF signaling pathway
0.1 12.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.1 PID_BMP_PATHWAY BMP receptor signaling
0.1 7.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 13.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.5 PID_BARD1_PATHWAY BARD1 signaling events
0.1 2.0 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 1.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 0.2 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.1 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.9 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 5.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 1.3 PID_MYC_PATHWAY C-MYC pathway
0.1 3.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID_ARF_3PATHWAY Arf1 pathway
0.1 2.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.8 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.9 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 2.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 3.1 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 2.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 2.1 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.1 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.2 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.4 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
2.0 11.9 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
1.8 10.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.4 12.7 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
1.1 25.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.6 2.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.6 10.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 8.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 4.9 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.4 4.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.4 3.7 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 9.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.3 2.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 9.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 3.0 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 5.8 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.2 6.4 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 3.1 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 5.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 4.9 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 4.7 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 2.0 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 2.1 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 2.0 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 1.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 5.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.3 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 3.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.9 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.8 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 7.4 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 3.8 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.0 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.9 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.1 2.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 2.1 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 1.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 8.0 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 3.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.5 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.3 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 1.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 4.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 2.3 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.5 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.4 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 1.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.4 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 7.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.3 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 1.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 1.1 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling