Motif ID: Rxrb

Z-value: 0.641


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032348_340324010.153.4e-01Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_117178726 4.515 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr1_+_6487231 4.148 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr6_-_23248264 3.828 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr10_-_88146867 3.078 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr10_+_93641041 3.066 ENSMUST00000020204.4
Ntn4
netrin 4
chr4_+_44300876 3.056 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr5_+_47984571 3.016 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr1_+_74791516 2.794 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr14_+_54476100 2.735 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr5_+_110839973 2.706 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr11_-_40733373 2.705 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr6_+_113531675 2.670 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr12_-_98737405 2.346 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr1_-_170306332 2.207 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr17_-_35704000 2.123 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr13_+_44729794 2.029 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr14_-_118052235 1.891 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr5_+_137630116 1.862 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_+_102706356 1.802 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chrX_-_23365044 1.795 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr6_+_29396576 1.723 ENSMUST00000115275.1
Ccdc136
coiled-coil domain containing 136
chr8_-_67910911 1.645 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr6_+_29396665 1.619 ENSMUST00000096084.5
Ccdc136
coiled-coil domain containing 136
chr8_+_72135247 1.464 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr3_+_122729158 1.385 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr14_+_20929416 1.327 ENSMUST00000022369.7
Vcl
vinculin
chr2_+_154548888 1.268 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr17_+_17831004 1.258 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr4_-_20778527 1.237 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr12_-_113260217 1.137 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr1_+_146420434 1.124 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr11_+_40733936 1.109 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr14_+_21500879 1.084 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr5_+_3803160 1.039 ENSMUST00000171023.1
ENSMUST00000080085.4
Krit1

KRIT1, ankyrin repeat containing

chr4_-_45532470 1.029 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr4_-_20778852 1.017 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chrX_+_73716712 0.945 ENSMUST00000114461.2
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chrX_+_73716577 0.894 ENSMUST00000002084.7
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr14_-_118706180 0.889 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr11_+_40733639 0.879 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr18_+_57142782 0.855 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr10_+_127195240 0.842 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr15_+_76797628 0.808 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr6_+_120836201 0.802 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr3_-_96172384 0.801 ENSMUST00000180958.1
Gm17690
predicted gene, 17690
chr12_+_119945957 0.788 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr2_-_119477613 0.755 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr7_-_4778141 0.747 ENSMUST00000094892.5
Il11
interleukin 11
chr5_+_119834663 0.747 ENSMUST00000018407.6
Tbx5
T-box 5
chr10_+_80148263 0.681 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn

midnolin

chr5_-_116422858 0.675 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr5_+_108065742 0.672 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr5_+_108065696 0.632 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr16_+_31663841 0.631 ENSMUST00000115201.1
Dlg1
discs, large homolog 1 (Drosophila)
chr19_-_4615453 0.630 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr3_+_90062781 0.618 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr7_+_3290553 0.608 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr10_+_81136223 0.606 ENSMUST00000048128.8
Zbtb7a
zinc finger and BTB domain containing 7a
chr10_+_88147061 0.596 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr2_+_118900377 0.564 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr7_-_35802968 0.557 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chr4_-_41048124 0.532 ENSMUST00000030136.6
Aqp7
aquaporin 7
chr7_+_35802593 0.509 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr7_-_31055594 0.484 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr16_+_24721842 0.478 ENSMUST00000115314.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr10_+_88146992 0.476 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr13_+_55209776 0.451 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chrX_+_10485121 0.451 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr9_-_50659780 0.444 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr4_+_43632185 0.427 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr16_+_31663935 0.424 ENSMUST00000100001.3
ENSMUST00000064477.7
Dlg1

discs, large homolog 1 (Drosophila)

chr2_+_112265809 0.419 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr2_+_158794807 0.372 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr1_+_86021935 0.370 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr11_-_70255329 0.350 ENSMUST00000108574.2
ENSMUST00000000329.2
Alox12

arachidonate 12-lipoxygenase

chr4_-_58912678 0.327 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr14_-_55106547 0.320 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr13_-_54688264 0.315 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr18_-_80713062 0.314 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr18_+_60774510 0.305 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr5_-_74702891 0.299 ENSMUST00000117388.1
Lnx1
ligand of numb-protein X 1
chr4_+_130047840 0.291 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr18_+_60774675 0.285 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr10_-_128547722 0.273 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr2_+_173659760 0.247 ENSMUST00000029024.3
Rab22a
RAB22A, member RAS oncogene family
chr2_+_173659834 0.229 ENSMUST00000109110.3
Rab22a
RAB22A, member RAS oncogene family
chr1_+_84839833 0.218 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr2_-_73911323 0.200 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr11_-_29547820 0.199 ENSMUST00000102844.3
Rps27a
ribosomal protein S27A
chr11_+_101070012 0.185 ENSMUST00000001802.9
Naglu
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr2_+_121449362 0.183 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr16_-_76403673 0.166 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr6_+_147531392 0.163 ENSMUST00000111614.2
Ccdc91
coiled-coil domain containing 91
chr5_-_134946917 0.152 ENSMUST00000051401.2
Cldn4
claudin 4
chr1_+_167618246 0.147 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr7_+_102229999 0.145 ENSMUST00000120119.1
Pgap2
post-GPI attachment to proteins 2
chr13_-_54688246 0.138 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr6_-_88446491 0.109 ENSMUST00000165242.1
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr10_+_127290774 0.103 ENSMUST00000026475.8
ENSMUST00000139091.1
Ddit3

DNA-damage inducible transcript 3

chr11_-_23519181 0.100 ENSMUST00000020527.5
1700093K21Rik
RIKEN cDNA 1700093K21 gene
chr10_-_53647080 0.097 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr11_-_97629685 0.092 ENSMUST00000052281.4
E130012A19Rik
RIKEN cDNA E130012A19 gene
chr12_+_111713255 0.091 ENSMUST00000040519.5
ENSMUST00000160366.1
ENSMUST00000163220.2
ENSMUST00000162316.1
Apopt1



apoptogenic, mitochondrial 1



chr1_+_131910458 0.087 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_72914264 0.074 ENSMUST00000144843.1
Slain2
SLAIN motif family, member 2
chr5_+_72914554 0.072 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr17_+_28177339 0.070 ENSMUST00000073534.2
ENSMUST00000002318.1
Zfp523

zinc finger protein 523

chr11_+_97315716 0.066 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr4_+_57845240 0.055 ENSMUST00000102903.1
ENSMUST00000107598.3
Akap2

A kinase (PRKA) anchor protein 2

chr17_-_32388885 0.044 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr16_+_10545390 0.030 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr1_-_52499980 0.028 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr11_-_97699634 0.013 ENSMUST00000103148.1
ENSMUST00000169807.1
Pcgf2

polycomb group ring finger 2

chr2_-_119662756 0.004 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr10_-_128821576 0.001 ENSMUST00000026409.3
Ormdl2
ORM1-like 2 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.9 4.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.7 2.7 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.6 3.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 3.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 1.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.5 1.9 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.5 1.4 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.4 2.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 3.5 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 2.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 1.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.3 1.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.3 1.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 3.3 GO:0001675 acrosome assembly(GO:0001675)
0.3 2.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 3.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 2.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 2.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.1 1.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.9 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.5 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.9 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 1.1 GO:0002385 mucosal immune response(GO:0002385)
0.1 0.5 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of inorganic anion transmembrane transport(GO:1903795)
0.1 1.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.5 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0071472 rubidium ion transport(GO:0035826) cellular response to salt stress(GO:0071472) cellular hypotonic response(GO:0071476)
0.1 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 2.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.8 GO:0006457 protein folding(GO:0006457)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 3.3 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 3.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 4.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.7 GO:0031011 Ino80 complex(GO:0031011)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 6.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.0 GO:0000776 kinetochore(GO:0000776)
0.0 2.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 3.7 GO:0005938 cell cortex(GO:0005938)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.1 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 4.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.1 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 2.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 3.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 2.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 3.9 GO:0001047 core promoter binding(GO:0001047)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 5.4 PID_ATM_PATHWAY ATM pathway
0.1 3.0 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 3.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 1.0 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 3.7 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 2.9 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 2.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 2.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 4.5 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.8 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex