Motif ID: Sox7

Z-value: 0.574


Transcription factors associated with Sox7:

Gene SymbolEntrez IDGene Name
Sox7 ENSMUSG00000063060.5 Sox7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox7mm10_v2_chr14_+_63943666_639436870.279.7e-02Click!


Activity profile for motif Sox7.

activity profile for motif Sox7


Sorted Z-values histogram for motif Sox7

Sorted Z-values for motif Sox7



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_103422010 11.525 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr19_+_26623419 2.742 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_93452679 2.628 ENSMUST00000111257.1
ENSMUST00000145553.1
Cd82

CD82 antigen

chr15_+_21111452 2.387 ENSMUST00000075132.6
Cdh12
cadherin 12
chr7_-_14562171 1.819 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr6_-_99266494 1.507 ENSMUST00000113326.2
Foxp1
forkhead box P1
chr7_+_78578830 1.304 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr18_+_12741324 0.978 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr15_+_16778101 0.851 ENSMUST00000026432.6
Cdh9
cadherin 9
chr5_-_107875035 0.720 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr9_-_101198999 0.700 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr12_-_20900867 0.624 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr10_-_69212996 0.442 ENSMUST00000170048.1
A930033H14Rik
RIKEN cDNA A930033H14 gene
chr7_+_30650385 0.421 ENSMUST00000181529.1
Gm26610
predicted gene, 26610
chr16_+_91391721 0.415 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr12_+_109734969 0.386 ENSMUST00000182268.1
ENSMUST00000181543.2
ENSMUST00000183116.1
Mirg


miRNA containing gene


chr10_-_79614012 0.309 ENSMUST00000059699.7
ENSMUST00000178228.1
C2cd4c

C2 calcium-dependent domain containing 4C

chr16_-_11176270 0.282 ENSMUST00000037633.8
Zc3h7a
zinc finger CCCH type containing 7 A
chr12_-_75735729 0.276 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr8_+_106935720 0.255 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr2_-_6130117 0.222 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
Proser2


proline and serine rich 2


chr14_+_113314602 0.191 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr1_+_169929929 0.187 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr2_+_19344317 0.133 ENSMUST00000141289.1
4930447M23Rik
RIKEN cDNA 4930447M23 gene
chr6_+_48684570 0.104 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
Gimap4




GTPase, IMAP family member 4




chr9_+_50575273 0.080 ENSMUST00000059081.6
ENSMUST00000180021.1
Il18

interleukin 18

chr9_-_36767595 0.055 ENSMUST00000120381.2
Stt3a
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr19_+_41593363 0.049 ENSMUST00000099454.3
AI606181
expressed sequence AI606181
chr7_-_99182681 0.048 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr3_-_86920830 0.023 ENSMUST00000029719.8
Dclk2
doublecortin-like kinase 2
chr10_+_7667503 0.014 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr3_-_151762906 0.007 ENSMUST00000046739.4
Ifi44l
interferon-induced protein 44 like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.5 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.8 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.1 GO:0032817 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 GO:0071564 npBAF complex(GO:0071564)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 1.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions