Motif ID: Stat5a
Z-value: 0.997
Transcription factors associated with Stat5a:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Stat5a | ENSMUSG00000004043.8 | Stat5a |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.1 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 1.0 | 4.0 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 1.0 | 2.9 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
| 1.0 | 2.9 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.9 | 2.6 | GO:0010752 | signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) |
| 0.9 | 2.6 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
| 0.7 | 1.4 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.7 | 2.7 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.7 | 2.7 | GO:0035937 | androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 0.6 | 3.8 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 0.6 | 1.9 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
| 0.6 | 1.8 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.6 | 3.5 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.5 | 2.1 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.5 | 1.5 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.5 | 2.8 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.5 | 1.4 | GO:0001757 | somite specification(GO:0001757) |
| 0.4 | 1.3 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.4 | 1.3 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 0.4 | 1.7 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.4 | 1.3 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
| 0.4 | 1.2 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.4 | 2.0 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.4 | 2.4 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.4 | 1.2 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.4 | 1.2 | GO:0044413 | regulation of lung blood pressure(GO:0014916) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
| 0.4 | 1.5 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.4 | 0.7 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.4 | 1.4 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.4 | 1.1 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 0.3 | 13.5 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.3 | 1.4 | GO:0019062 | virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650) |
| 0.3 | 1.7 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.3 | 1.0 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
| 0.3 | 0.3 | GO:0046101 | hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) |
| 0.3 | 0.9 | GO:0070366 | regulation of hepatocyte differentiation(GO:0070366) |
| 0.3 | 0.9 | GO:0043096 | purine nucleobase salvage(GO:0043096) |
| 0.3 | 0.9 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.3 | 3.3 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.3 | 0.9 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 0.3 | 1.2 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.3 | 0.3 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.3 | 1.8 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.3 | 0.9 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.3 | 0.6 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
| 0.3 | 0.5 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
| 0.3 | 0.8 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.3 | 0.8 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
| 0.3 | 1.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.2 | 2.2 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.2 | 0.7 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.2 | 0.7 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.2 | 0.7 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
| 0.2 | 1.9 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.2 | 0.5 | GO:1903542 | negative regulation of exosomal secretion(GO:1903542) |
| 0.2 | 2.5 | GO:0030432 | peristalsis(GO:0030432) |
| 0.2 | 1.1 | GO:2000427 | eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.2 | 1.5 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.2 | 1.5 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 0.2 | 0.9 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.2 | 1.5 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.2 | 0.6 | GO:0032621 | interleukin-18 production(GO:0032621) |
| 0.2 | 0.4 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 0.2 | 1.1 | GO:0010637 | diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637) |
| 0.2 | 0.6 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 0.2 | 0.6 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.2 | 0.4 | GO:0002481 | antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) |
| 0.2 | 0.6 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.2 | 0.6 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.2 | 1.0 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.2 | 0.6 | GO:0015866 | ADP transport(GO:0015866) |
| 0.2 | 1.2 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.2 | 0.6 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.2 | 4.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 0.6 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.2 | 1.4 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.2 | 0.5 | GO:0045575 | basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575) |
| 0.2 | 0.5 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
| 0.2 | 1.0 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.2 | 1.0 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.2 | 0.8 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 0.2 | 0.2 | GO:1901536 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
| 0.2 | 0.5 | GO:0048239 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.2 | 0.7 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
| 0.2 | 0.7 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.2 | 0.8 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.2 | 0.8 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.2 | 1.0 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.2 | 1.2 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.2 | 0.6 | GO:0001771 | immunological synapse formation(GO:0001771) |
| 0.1 | 0.6 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.1 | 0.6 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.1 | 0.7 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.1 | 0.6 | GO:0002922 | positive regulation of humoral immune response(GO:0002922) |
| 0.1 | 0.1 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) |
| 0.1 | 0.4 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.1 | 0.7 | GO:0002606 | dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606) |
| 0.1 | 0.3 | GO:0032224 | positive regulation of synaptic transmission, cholinergic(GO:0032224) |
| 0.1 | 0.3 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.1 | 1.5 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 0.5 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.1 | 0.4 | GO:0097350 | neutrophil clearance(GO:0097350) |
| 0.1 | 1.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.1 | 0.9 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146) |
| 0.1 | 1.9 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 0.5 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 0.1 | 3.4 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.1 | 0.6 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.1 | 0.5 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.1 | 1.1 | GO:0097384 | cellular lipid biosynthetic process(GO:0097384) |
| 0.1 | 0.4 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) |
| 0.1 | 0.6 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.1 | 0.5 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.1 | 0.2 | GO:0035106 | operant conditioning(GO:0035106) |
| 0.1 | 0.8 | GO:1902856 | negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.1 | 0.6 | GO:0072235 | distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) |
| 0.1 | 0.8 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.1 | 1.6 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.1 | 1.0 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
| 0.1 | 0.5 | GO:0072257 | condensed mesenchymal cell proliferation(GO:0072137) metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.1 | 0.8 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.1 | 0.3 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.1 | 1.5 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.1 | 1.8 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.1 | 2.1 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.1 | 0.1 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.1 | 0.8 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 0.7 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 0.1 | 0.5 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.1 | 0.4 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 0.4 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.1 | 0.8 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.1 | 0.3 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.1 | 1.7 | GO:0001553 | luteinization(GO:0001553) |
| 0.1 | 0.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 0.4 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
| 0.1 | 3.1 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.1 | 0.4 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.1 | 0.8 | GO:0044539 | long-chain fatty acid import(GO:0044539) |
| 0.1 | 0.5 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.1 | 0.2 | GO:1902947 | regulation of tau-protein kinase activity(GO:1902947) |
| 0.1 | 1.2 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 3.4 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.1 | 0.7 | GO:0072656 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) maintenance of protein location in mitochondrion(GO:0072656) |
| 0.1 | 0.4 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.3 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
| 0.1 | 0.9 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.1 | 0.9 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.1 | 0.6 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.1 | 2.7 | GO:0034340 | response to type I interferon(GO:0034340) |
| 0.1 | 0.4 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 0.3 | GO:0010755 | regulation of plasminogen activation(GO:0010755) |
| 0.1 | 1.2 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 0.5 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.1 | 1.6 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.1 | 1.4 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.1 | 0.4 | GO:1905245 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.1 | 0.4 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.3 | GO:0098912 | smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.1 | 0.2 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.1 | 0.3 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.1 | 0.4 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.1 | 0.2 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.1 | 0.2 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.1 | 0.3 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.1 | 0.2 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.1 | 0.6 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.1 | 1.3 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.1 | 1.5 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 0.3 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.1 | 1.7 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.1 | 0.2 | GO:0003032 | detection of oxygen(GO:0003032) |
| 0.1 | 0.5 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.3 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.1 | 0.3 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.1 | 0.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 0.8 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.1 | 0.6 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.1 | 0.5 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.1 | 0.2 | GO:2000569 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 0.1 | 0.7 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.1 | 0.2 | GO:0051715 | cytolysis in other organism(GO:0051715) |
| 0.1 | 0.1 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.1 | 0.2 | GO:0046381 | CMP-N-acetylneuraminate metabolic process(GO:0046381) |
| 0.1 | 0.3 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
| 0.1 | 0.3 | GO:0021508 | ventral midline development(GO:0007418) floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505) |
| 0.1 | 1.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 0.2 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.1 | 1.6 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.1 | 0.4 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
| 0.1 | 1.8 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 0.4 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
| 0.1 | 0.6 | GO:1902913 | regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) positive regulation of developmental pigmentation(GO:0048087) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913) |
| 0.1 | 0.1 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.2 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.1 | 0.8 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.4 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.3 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 0.3 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.1 | 0.2 | GO:0045349 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) |
| 0.1 | 0.3 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.1 | 0.7 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 0.2 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 0.1 | 0.2 | GO:0002265 | astrocyte activation involved in immune response(GO:0002265) |
| 0.1 | 0.3 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
| 0.1 | 0.5 | GO:0098907 | T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.1 | 0.3 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.1 | 0.3 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.1 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 0.3 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.1 | 0.3 | GO:1903012 | positive regulation of bone development(GO:1903012) |
| 0.1 | 0.4 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 0.3 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.1 | 0.5 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.1 | 0.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.1 | 0.2 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.1 | 0.5 | GO:0071941 | nitrogen cycle metabolic process(GO:0071941) |
| 0.1 | 0.2 | GO:0010896 | negative regulation of sequestering of triglyceride(GO:0010891) regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.1 | 0.4 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.0 | 0.1 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.0 | 0.7 | GO:0018195 | peptidyl-arginine modification(GO:0018195) |
| 0.0 | 1.1 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.0 | 1.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.4 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.0 | 0.2 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.0 | 0.3 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.0 | 0.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.0 | 0.8 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.0 | 0.0 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
| 0.0 | 0.1 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.0 | 0.1 | GO:0006154 | adenosine catabolic process(GO:0006154) |
| 0.0 | 0.4 | GO:0021678 | third ventricle development(GO:0021678) |
| 0.0 | 0.3 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.0 | 0.3 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.0 | 0.2 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 0.2 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.0 | 0.2 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.0 | 0.2 | GO:0033602 | negative regulation of dopamine secretion(GO:0033602) |
| 0.0 | 0.1 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.0 | 0.6 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.2 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
| 0.0 | 0.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.3 | GO:0052646 | alditol phosphate metabolic process(GO:0052646) |
| 0.0 | 0.1 | GO:1903772 | regulation of viral budding via host ESCRT complex(GO:1903772) |
| 0.0 | 0.4 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.0 | 1.8 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.0 | 0.0 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.2 | GO:0090188 | negative regulation of pancreatic juice secretion(GO:0090188) |
| 0.0 | 0.1 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.0 | 0.2 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.0 | 0.7 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 0.0 | 0.1 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.0 | 0.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.0 | 0.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.1 | GO:0046032 | ADP catabolic process(GO:0046032) |
| 0.0 | 0.1 | GO:0046655 | glycine biosynthetic process(GO:0006545) folic acid metabolic process(GO:0046655) |
| 0.0 | 0.1 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.0 | 0.2 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.0 | 0.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
| 0.0 | 0.2 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.0 | 0.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 1.3 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.1 | GO:0032240 | negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.0 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 0.1 | GO:0097501 | stress response to metal ion(GO:0097501) |
| 0.0 | 0.3 | GO:0006007 | glucose catabolic process(GO:0006007) |
| 0.0 | 0.5 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.2 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.0 | 1.2 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.0 | 0.1 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.0 | 0.6 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 0.3 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.0 | 0.2 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.0 | 0.5 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 1.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.2 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.0 | 1.0 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.3 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
| 0.0 | 0.1 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.7 | GO:0048668 | collateral sprouting(GO:0048668) |
| 0.0 | 0.5 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
| 0.0 | 0.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 0.1 | GO:0014874 | response to stimulus involved in regulation of muscle adaptation(GO:0014874) |
| 0.0 | 1.6 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.0 | 0.1 | GO:0071286 | cellular response to magnesium ion(GO:0071286) |
| 0.0 | 3.4 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.2 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.0 | 0.1 | GO:0044241 | lipid digestion(GO:0044241) |
| 0.0 | 0.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 0.3 | GO:0015809 | arginine transport(GO:0015809) |
| 0.0 | 0.1 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) |
| 0.0 | 0.3 | GO:0070243 | regulation of thymocyte apoptotic process(GO:0070243) |
| 0.0 | 0.2 | GO:0031442 | positive regulation of mRNA 3'-end processing(GO:0031442) |
| 0.0 | 0.5 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 0.3 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.4 | GO:1901032 | negative regulation of response to reactive oxygen species(GO:1901032) negative regulation of hydrogen peroxide-induced cell death(GO:1903206) |
| 0.0 | 0.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.1 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.0 | 0.2 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.0 | 0.1 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.7 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 0.6 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.0 | 0.1 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.0 | 1.4 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.0 | 0.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.0 | 0.3 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.0 | 0.1 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.0 | 0.7 | GO:1903078 | positive regulation of protein localization to plasma membrane(GO:1903078) |
| 0.0 | 0.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.5 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.0 | 0.0 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.0 | 0.1 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.1 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.0 | 0.1 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 0.0 | 0.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 0.1 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 0.0 | 0.3 | GO:0055010 | ventricular cardiac muscle tissue morphogenesis(GO:0055010) |
| 0.0 | 0.1 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.1 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.1 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
| 0.0 | 0.3 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 0.2 | GO:0015824 | proline transport(GO:0015824) |
| 0.0 | 1.4 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.1 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.0 | 0.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.1 | GO:0039702 | viral budding via host ESCRT complex(GO:0039702) |
| 0.0 | 1.0 | GO:0050810 | regulation of steroid biosynthetic process(GO:0050810) |
| 0.0 | 0.3 | GO:0008206 | bile acid metabolic process(GO:0008206) |
| 0.0 | 0.2 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.0 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.0 | 0.4 | GO:0010453 | regulation of cell fate commitment(GO:0010453) |
| 0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 0.2 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.1 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.0 | 0.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.0 | 0.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.5 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.1 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.1 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.3 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.1 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.0 | 0.4 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.0 | 0.2 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 0.3 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186) |
| 0.0 | 0.0 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.0 | 0.1 | GO:0015919 | peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046) |
| 0.0 | 0.1 | GO:0051591 | response to cAMP(GO:0051591) |
| 0.0 | 0.7 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.0 | 0.6 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.0 | 0.3 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.0 | 0.2 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.0 | 0.3 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.4 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.1 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.0 | 0.2 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.0 | 0.2 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.0 | 0.0 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 0.0 | 0.0 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.0 | 0.2 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.0 | 0.0 | GO:0033007 | negative regulation of mast cell activation involved in immune response(GO:0033007) response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) negative regulation of mast cell degranulation(GO:0043305) |
| 0.0 | 0.1 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.0 | 0.2 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 6.6 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.9 | 2.8 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.9 | 3.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.7 | 3.0 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.6 | 1.8 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
| 0.5 | 3.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.4 | 1.1 | GO:0044299 | C-fiber(GO:0044299) |
| 0.4 | 1.1 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.4 | 0.4 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.3 | 1.3 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.3 | 5.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 1.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.3 | 1.2 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.3 | 3.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 0.8 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.2 | 0.5 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.2 | 1.2 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 1.2 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.2 | 1.2 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.2 | 0.7 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.2 | 1.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.2 | 1.0 | GO:1990357 | terminal web(GO:1990357) |
| 0.2 | 0.8 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.2 | 1.0 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.2 | 1.2 | GO:0042825 | TAP complex(GO:0042825) |
| 0.2 | 0.8 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.2 | 1.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.2 | 2.6 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 1.0 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 1.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 0.4 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.1 | 0.5 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 1.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.7 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.5 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.1 | 0.4 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.1 | 8.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 0.6 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.6 | GO:1990745 | EARP complex(GO:1990745) |
| 0.1 | 1.4 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) |
| 0.1 | 0.7 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.6 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.1 | 1.4 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.1 | 0.4 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.1 | 1.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.3 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 0.1 | 0.5 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 0.9 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.1 | 0.3 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
| 0.1 | 0.4 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 1.1 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 9.5 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 1.1 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 1.0 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 0.1 | 10.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 0.3 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.1 | 0.4 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.1 | 0.5 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 1.0 | GO:0046930 | pore complex(GO:0046930) |
| 0.1 | 0.8 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.1 | 0.7 | GO:0032009 | early phagosome(GO:0032009) |
| 0.1 | 0.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.7 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 0.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.6 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.1 | 0.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.1 | 1.3 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 1.0 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.1 | 0.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 1.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.4 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.0 | 0.9 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.4 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 0.2 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 0.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.2 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.9 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.0 | 0.6 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.3 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.2 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) tertiary granule(GO:0070820) |
| 0.0 | 0.2 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.0 | 1.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.6 | GO:0020003 | symbiont-containing vacuole(GO:0020003) extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.3 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.2 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 2.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 2.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 1.5 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 0.1 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.0 | 0.1 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 2.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.3 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.2 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.0 | 1.1 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.2 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.4 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.0 | 0.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.2 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 0.2 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.4 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 0.1 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.0 | 0.4 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 3.1 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.2 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 0.2 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 2.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.1 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 2.1 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.7 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.2 | GO:0061700 | Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700) |
| 0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 1.3 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 2.2 | GO:0030017 | sarcomere(GO:0030017) |
| 0.0 | 0.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 1.2 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.1 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 1.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.2 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 0.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 0.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.1 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 14.5 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 2.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.2 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.2 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.3 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 0.4 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.2 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 1.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.2 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 0.3 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.0 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.1 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 0.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.4 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 4.8 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 1.2 | 3.5 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 1.0 | 2.9 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.6 | 3.7 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.6 | 2.5 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.5 | 2.1 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.5 | 3.3 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.4 | 1.3 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 0.4 | 1.3 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
| 0.4 | 1.3 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.4 | 1.2 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.3 | 1.7 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.3 | 2.6 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.3 | 1.3 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 0.3 | 1.2 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980) |
| 0.3 | 2.7 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.3 | 0.9 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.3 | 2.0 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.3 | 0.9 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.3 | 4.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.3 | 1.1 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.3 | 3.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 1.0 | GO:0019962 | interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) |
| 0.2 | 0.7 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
| 0.2 | 0.7 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.2 | 1.0 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.2 | 1.4 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 1.2 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.2 | 1.2 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.2 | 1.1 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 0.2 | 0.9 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.2 | 1.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.5 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.2 | 1.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.2 | 0.6 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
| 0.2 | 2.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 1.0 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
| 0.2 | 0.6 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
| 0.2 | 3.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 0.6 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.2 | 1.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 1.9 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.2 | 2.7 | GO:0005537 | mannose binding(GO:0005537) |
| 0.2 | 2.9 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 1.2 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.2 | 0.7 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
| 0.2 | 0.5 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.2 | 2.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.2 | 1.0 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
| 0.2 | 0.5 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.2 | 1.0 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.2 | 1.0 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 0.5 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.2 | 8.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 0.4 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 1.6 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.7 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.4 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
| 0.1 | 0.7 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.1 | 0.7 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 1.6 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 0.1 | 0.4 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.1 | 0.8 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 1.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 1.6 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.1 | 0.9 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.1 | 1.5 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.6 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.5 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.1 | 0.5 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.1 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.7 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 0.7 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.1 | 0.3 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.1 | 0.3 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.1 | 0.3 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 0.5 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.1 | 2.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.6 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 2.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 1.7 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.1 | 0.4 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.1 | 0.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 0.6 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.4 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 1.1 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.1 | 0.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 0.3 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.1 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.3 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.1 | 0.3 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.1 | 0.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.1 | 0.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 0.8 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.6 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 1.9 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.1 | 1.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 9.2 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.1 | 0.4 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.1 | 0.4 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.1 | 0.4 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 0.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.3 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 0.3 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 0.3 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.1 | 0.3 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.1 | 1.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.3 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
| 0.1 | 0.2 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 0.5 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.1 | 0.2 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.1 | 2.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 0.9 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.1 | 0.9 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 0.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.4 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 1.8 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.2 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.1 | 1.8 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 1.5 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 0.9 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 0.4 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.0 | 7.2 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.0 | 0.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 0.3 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.5 | GO:0046977 | TAP binding(GO:0046977) |
| 0.0 | 0.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.0 | 1.0 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.9 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 0.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.4 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 1.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 1.9 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 1.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.2 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.0 | 0.7 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.0 | 0.2 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 0.2 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.0 | 2.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.5 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.5 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.0 | 1.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.8 | GO:0005272 | sodium channel activity(GO:0005272) |
| 0.0 | 0.5 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.1 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.0 | 0.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905) |
| 0.0 | 1.0 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.0 | 0.2 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.0 | 0.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.3 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.0 | 1.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.2 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.0 | 0.1 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 0.4 | GO:0004559 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
| 0.0 | 0.1 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.0 | 0.3 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 0.0 | 0.1 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 0.0 | 0.1 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.0 | 0.3 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.9 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.3 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.4 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.0 | 0.4 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.0 | 0.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.0 | 0.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.0 | 0.2 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.0 | 0.1 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 0.2 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.0 | 0.8 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.1 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.0 | 0.4 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.0 | 0.1 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.0 | 0.1 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 0.1 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.0 | 0.1 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.0 | 0.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.1 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.0 | 0.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.1 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 0.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.1 | GO:0035473 | lipase binding(GO:0035473) |
| 0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.2 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.0 | 0.1 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
| 0.0 | 1.1 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.1 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.0 | 0.2 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.4 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.3 | GO:0023023 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
| 0.0 | 0.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.2 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.0 | 0.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 2.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.1 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.1 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.0 | 0.1 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 0.2 | GO:0019825 | oxygen binding(GO:0019825) |
| 0.0 | 3.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.4 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 0.0 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 0.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 4.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.1 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.0 | 0.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.1 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.0 | 0.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.1 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.0 | 0.0 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.0 | 0.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.3 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.1 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 0.2 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.2 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.1 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.5 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.2 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 0.0 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.1 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.2 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 0.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.4 | GO:0070888 | E-box binding(GO:0070888) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.8 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
| 0.3 | 18.1 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 1.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.1 | 1.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 1.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 2.8 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.6 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
| 0.1 | 1.2 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 0.4 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 0.6 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.1 | 9.7 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 4.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.1 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 1.3 | PID_ENDOTHELIN_PATHWAY | Endothelins |
| 0.0 | 0.8 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 2.1 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 5.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.6 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 4.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.5 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.0 | 2.0 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 2.8 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.6 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.9 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 1.1 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.5 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.1 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.7 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.0 | 0.2 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.0 | 0.8 | PID_CD8_TCR_DOWNSTREAM_PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 0.2 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 0.2 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 0.4 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.6 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 0.2 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.6 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.5 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 0.4 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.2 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.1 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.3 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.0 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.1 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.1 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 1.5 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 0.3 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.2 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.2 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.3 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.1 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.0 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.3 | 3.4 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.3 | 1.1 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 3.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.2 | 3.5 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 1.5 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 1.4 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.2 | 0.2 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.2 | 2.6 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.2 | 3.9 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 2.0 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 10.4 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 3.6 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.3 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 0.7 | REACTOME_PD1_SIGNALING | Genes involved in PD-1 signaling |
| 0.1 | 2.5 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 0.9 | REACTOME_LIPOPROTEIN_METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.1 | 1.3 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 1.0 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 5.3 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.1 | 5.3 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 1.7 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 1.0 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 1.9 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 0.4 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 3.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.2 | REACTOME_IRON_UPTAKE_AND_TRANSPORT | Genes involved in Iron uptake and transport |
| 0.1 | 1.8 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 0.3 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 0.4 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.0 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.1 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 1.7 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.6 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.6 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.8 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.0 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 2.6 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.2 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 1.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.8 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 1.4 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 1.8 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 1.3 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.6 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_IFNA_SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.9 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.8 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 2.0 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 0.7 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.5 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 4.8 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.4 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.4 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.1 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
| 0.0 | 0.4 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.9 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.4 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.1 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 0.2 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.4 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.8 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.4 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 1.1 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.1 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.2 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.2 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.1 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.3 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 0.1 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 1.1 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.2 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 0.3 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 1.2 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
