Motif ID: Taf1

Z-value: 4.239


Transcription factors associated with Taf1:

Gene SymbolEntrez IDGene Name
Taf1 ENSMUSG00000031314.11 Taf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Taf1mm10_v2_chrX_+_101532734_1015327770.752.0e-08Click!


Activity profile for motif Taf1.

activity profile for motif Taf1


Sorted Z-values histogram for motif Taf1

Sorted Z-values for motif Taf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Taf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_119047116 26.541 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr2_+_119047129 23.899 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr5_-_123749393 21.401 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 21.395 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chr3_+_69004969 20.411 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr3_+_69004711 19.106 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr7_+_59228743 16.440 ENSMUST00000107537.1
Ube3a
ubiquitin protein ligase E3A
chr9_+_80067452 13.886 ENSMUST00000165607.2
Senp6
SUMO/sentrin specific peptidase 6
chr19_+_34922351 13.418 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr5_+_23434435 13.253 ENSMUST00000094962.2
ENSMUST00000115128.1
Kmt2e

lysine (K)-specific methyltransferase 2E

chr12_-_101083653 13.074 ENSMUST00000048305.8
ENSMUST00000163095.1
Smek1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

chr10_+_79854618 12.808 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chrX_-_103981242 12.557 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr12_+_83632208 12.516 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
Rbm25




RNA binding motif protein 25




chrX_-_103483205 12.432 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr18_-_6241470 12.408 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr6_+_38433913 12.305 ENSMUST00000160583.1
Ubn2
ubinuclein 2
chr18_-_6241486 12.239 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr7_+_123123870 12.051 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr5_+_108065742 11.567 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr9_+_122951051 10.866 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr4_-_116627478 10.829 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chrX_-_60403947 10.625 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr10_+_79854658 10.613 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr2_+_119618717 10.499 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chrX_-_108834303 10.380 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr4_-_62208426 10.299 ENSMUST00000068822.3
Zfp37
zinc finger protein 37
chr2_+_35109482 10.294 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
Cep110


centrosomal protein 110


chr12_+_71015966 10.223 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr9_-_72491939 10.155 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr2_+_52072823 9.747 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr4_+_21848039 9.637 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr3_-_133544390 9.553 ENSMUST00000098603.3
Tet2
tet methylcytosine dioxygenase 2
chr9_+_25252439 9.466 ENSMUST00000115272.2
ENSMUST00000165594.2
Sept7

septin 7

chr6_+_83914353 9.168 ENSMUST00000113835.3
ENSMUST00000032088.7
ENSMUST00000113836.3
Zfml


zinc finger, matrin-like


chr15_-_86033777 9.159 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr6_+_149408973 9.122 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr7_-_98656530 9.113 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr5_+_108065696 8.993 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr12_+_4917376 8.834 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B
chr12_-_98901478 8.595 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr3_-_84220853 8.534 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr11_-_77078404 8.483 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr10_+_108162358 8.424 ENSMUST00000070663.5
Ppp1r12a
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr18_-_10610346 8.373 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr3_-_95217690 8.130 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr10_+_41519493 8.116 ENSMUST00000019962.8
Cd164
CD164 antigen
chrX_+_57053549 8.064 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr4_-_34882919 7.974 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr1_+_150393250 7.925 ENSMUST00000119161.2
Tpr
translocated promoter region
chr19_+_41482632 7.900 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr16_-_33056174 7.888 ENSMUST00000115100.1
ENSMUST00000040309.8
Iqcg

IQ motif containing G

chrX_+_151520655 7.874 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8


PHD finger protein 8


chr17_-_71526819 7.822 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr9_+_72274860 7.797 ENSMUST00000184036.1
ENSMUST00000184517.1
ENSMUST00000098576.3
Zfp280d


zinc finger protein 280D


chr3_+_40800013 7.764 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr5_+_3928033 7.729 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chrX_-_113185485 7.683 ENSMUST00000026607.8
ENSMUST00000113388.2
Chm

choroidermia

chrX_+_13280970 7.641 ENSMUST00000000804.6
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr1_-_133661318 7.623 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr9_+_72274966 7.539 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr11_-_94321957 7.411 ENSMUST00000166312.1
ENSMUST00000107821.2
ENSMUST00000021226.7
ENSMUST00000107820.1
Luc7l3



LUC7-like 3 (S. cerevisiae)



chrX_-_41911877 7.355 ENSMUST00000047037.8
Thoc2
THO complex 2
chrX_-_105929333 7.319 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr5_+_3928267 7.313 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr1_+_178405881 7.301 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2
chr1_-_58424042 7.277 ENSMUST00000034868.7
Clk1
CDC-like kinase 1
chrX_-_105929397 7.229 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chrX_-_105929206 7.226 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr15_+_34082664 7.207 ENSMUST00000022865.9
Mtdh
metadherin
chr13_+_96542727 7.207 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr3_+_40800054 7.127 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr18_-_10610048 7.069 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr14_-_26534870 7.062 ENSMUST00000139075.1
ENSMUST00000102956.1
Slmap

sarcolemma associated protein

chr3_-_95217877 7.002 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr18_-_10610124 6.982 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr10_+_115384951 6.932 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr11_-_85235065 6.885 ENSMUST00000018625.9
Appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr5_-_9161692 6.861 ENSMUST00000183973.1
ENSMUST00000184372.1
ENSMUST00000095017.4
ENSMUST00000071921.6
Dmtf1



cyclin D binding myb-like transcription factor 1



chr16_+_37011758 6.808 ENSMUST00000071452.5
ENSMUST00000054034.6
Polq

polymerase (DNA directed), theta

chr2_+_172549581 6.781 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr14_+_56668242 6.675 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr2_+_23069057 6.674 ENSMUST00000114526.1
ENSMUST00000114529.2
Acbd5

acyl-Coenzyme A binding domain containing 5

chr7_+_97579868 6.640 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr5_+_76588663 6.637 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr7_-_127042420 6.605 ENSMUST00000032915.6
Kif22
kinesin family member 22
chr8_+_41239718 6.570 ENSMUST00000045218.7
Pcm1
pericentriolar material 1
chr15_-_58076456 6.561 ENSMUST00000070143.6
ENSMUST00000110168.1
Zhx1

zinc fingers and homeoboxes 1

chr13_-_47105790 6.545 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr12_-_108003414 6.526 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chrX_+_159255782 6.454 ENSMUST00000126686.1
ENSMUST00000033671.6
Rps6ka3

ribosomal protein S6 kinase polypeptide 3

chr1_-_162740350 6.387 ENSMUST00000182331.1
ENSMUST00000183011.1
ENSMUST00000182593.1
ENSMUST00000182149.1
Prrc2c



proline-rich coiled-coil 2C



chrX_-_111463149 6.359 ENSMUST00000096348.3
ENSMUST00000113428.2
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chrX_+_42149288 6.354 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr19_+_53600377 6.337 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr4_-_132422394 6.321 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr3_-_69004565 6.299 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr12_+_16810940 6.296 ENSMUST00000020908.7
E2f6
E2F transcription factor 6
chr4_-_11254248 6.244 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr11_-_100472725 6.223 ENSMUST00000056665.3
Klhl11
kelch-like 11
chrX_-_37110257 6.216 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr1_-_119837613 6.197 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr16_+_84834901 6.178 ENSMUST00000114184.1
Gabpa
GA repeat binding protein, alpha
chr7_-_92669917 6.171 ENSMUST00000119954.1
Pcf11
cleavage and polyadenylation factor subunit homolog (S. cerevisiae)
chr9_-_66919646 6.168 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr6_+_113531675 6.162 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr3_-_69004503 6.158 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr18_+_34624621 6.141 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr13_-_104816908 6.100 ENSMUST00000022228.6
Cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chrX_-_95026671 6.091 ENSMUST00000096367.3
Spin4
spindlin family, member 4
chr14_+_27428790 6.076 ENSMUST00000022450.4
D14Abb1e
DNA segment, Chr 14, Abbott 1 expressed
chr11_+_29172890 6.073 ENSMUST00000102856.2
ENSMUST00000020755.5
Smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

chr15_+_25622525 6.064 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr12_-_108003594 6.041 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr1_-_119837338 6.010 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chrX_-_104413825 6.007 ENSMUST00000033695.5
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr4_+_148039035 5.997 ENSMUST00000097788.4
Mthfr
5,10-methylenetetrahydrofolate reductase
chr11_+_23665615 5.976 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr1_+_127774164 5.941 ENSMUST00000027587.8
ENSMUST00000112570.1
Ccnt2

cyclin T2

chr12_+_111538819 5.935 ENSMUST00000050993.9
Eif5
eukaryotic translation initiation factor 5
chr11_-_17953861 5.905 ENSMUST00000076661.6
Etaa1
Ewing's tumor-associated antigen 1
chr2_+_173659760 5.895 ENSMUST00000029024.3
Rab22a
RAB22A, member RAS oncogene family
chr12_+_59066908 5.889 ENSMUST00000021381.4
Pnn
pinin
chr1_-_162740540 5.885 ENSMUST00000028016.9
ENSMUST00000182660.1
Prrc2c

proline-rich coiled-coil 2C

chr1_-_143702832 5.872 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr1_+_64532790 5.857 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
Creb1


cAMP responsive element binding protein 1


chr3_-_69004475 5.853 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr19_-_23273893 5.838 ENSMUST00000087556.5
Smc5
structural maintenance of chromosomes 5
chr8_-_111259192 5.825 ENSMUST00000169020.1
ENSMUST00000003404.8
Glg1

golgi apparatus protein 1

chr16_+_32332238 5.797 ENSMUST00000115151.3
Ubxn7
UBX domain protein 7
chr10_+_7681197 5.796 ENSMUST00000165952.1
Lats1
large tumor suppressor
chr6_-_95718800 5.783 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr6_+_91878034 5.783 ENSMUST00000037783.5
Ccdc174
coiled-coil domain containing 174
chr13_-_103920295 5.773 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr4_-_135873546 5.759 ENSMUST00000142585.1
Pnrc2
proline-rich nuclear receptor coactivator 2
chr13_-_100104064 5.752 ENSMUST00000038104.5
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr9_-_104262900 5.748 ENSMUST00000035170.6
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chrX_+_103356464 5.741 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr9_-_95511897 5.731 ENSMUST00000079659.5
ENSMUST00000078374.6
U2surp

U2 snRNP-associated SURP domain containing

chr1_+_130717320 5.685 ENSMUST00000049813.4
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr2_+_23069210 5.676 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr3_+_51415986 5.663 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr7_+_12478319 5.639 ENSMUST00000151933.1
Zfp606
zinc finger protein 606
chr9_+_3404058 5.639 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr1_-_166002613 5.628 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr9_+_70542872 5.627 ENSMUST00000049263.7
Sltm
SAFB-like, transcription modulator
chr12_-_102878406 5.621 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr5_+_15934685 5.612 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr4_+_49521176 5.611 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr4_-_121215071 5.591 ENSMUST00000056635.5
Rlf
rearranged L-myc fusion sequence
chr1_+_74601548 5.569 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chrX_-_111463043 5.569 ENSMUST00000065976.5
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr3_-_116423930 5.567 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chrX_-_23365044 5.557 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr4_-_70410422 5.553 ENSMUST00000144099.1
Cdk5rap2
CDK5 regulatory subunit associated protein 2
chr16_+_31664130 5.546 ENSMUST00000023454.5
Dlg1
discs, large homolog 1 (Drosophila)
chr3_+_116594959 5.544 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr10_-_62792243 5.484 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr2_+_128818104 5.484 ENSMUST00000110325.1
Tmem87b
transmembrane protein 87B
chr11_-_62457289 5.474 ENSMUST00000069456.4
ENSMUST00000018645.6
Ncor1

nuclear receptor co-repressor 1

chr3_+_34020075 5.456 ENSMUST00000001620.8
ENSMUST00000167354.1
Fxr1

fragile X mental retardation gene 1, autosomal homolog

chr18_+_34220890 5.451 ENSMUST00000171187.1
Apc
adenomatosis polyposis coli
chr19_+_3768112 5.448 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr14_+_47276910 5.444 ENSMUST00000065562.4
Socs4
suppressor of cytokine signaling 4
chr1_-_10232670 5.438 ENSMUST00000088615.4
ENSMUST00000131556.1
Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr4_+_12140263 5.420 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chr4_+_12089373 5.406 ENSMUST00000095143.2
ENSMUST00000063839.5
Rbm12b2

RNA binding motif protein 12 B2

chr18_-_46280820 5.375 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr12_-_4233958 5.337 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr16_+_31663841 5.320 ENSMUST00000115201.1
Dlg1
discs, large homolog 1 (Drosophila)
chr4_-_132422484 5.259 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr18_+_34220978 5.248 ENSMUST00000079362.5
ENSMUST00000115781.3
Apc

adenomatosis polyposis coli

chr2_+_128818295 5.248 ENSMUST00000178354.1
ENSMUST00000152210.1
Tmem87b

transmembrane protein 87B

chr5_-_21701332 5.246 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr14_-_105176860 5.242 ENSMUST00000163545.1
Rbm26
RNA binding motif protein 26
chrX_+_42149534 5.241 ENSMUST00000127618.1
Stag2
stromal antigen 2
chrX_-_147554050 5.238 ENSMUST00000112819.2
ENSMUST00000136789.1
Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr9_+_80066939 5.231 ENSMUST00000164859.1
Senp6
SUMO/sentrin specific peptidase 6
chr7_+_12478293 5.231 ENSMUST00000098822.3
Zfp606
zinc finger protein 606
chr1_-_36939521 5.190 ENSMUST00000027290.5
Tmem131
transmembrane protein 131
chr4_-_94979063 5.187 ENSMUST00000075872.3
Mysm1
myb-like, SWIRM and MPN domains 1
chr13_+_34875488 5.170 ENSMUST00000077853.3
Prpf4b
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr2_-_10048580 5.165 ENSMUST00000026888.4
Taf3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_+_69861638 5.149 ENSMUST00000112260.1
Ssb
Sjogren syndrome antigen B
chr17_+_80944611 5.137 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr13_+_81657732 5.135 ENSMUST00000049055.6
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr5_-_100038869 5.134 ENSMUST00000153442.1
Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr6_+_86404336 5.119 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr5_+_15934762 5.118 ENSMUST00000115281.2
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr16_+_84835070 5.101 ENSMUST00000009120.7
Gabpa
GA repeat binding protein, alpha
chr2_+_69861562 5.087 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr17_-_33685386 5.083 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm


heterogeneous nuclear ribonucleoprotein M


chr3_+_86224665 5.064 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr14_+_21500879 5.063 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr3_-_95217741 5.062 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr3_-_108911687 5.059 ENSMUST00000029480.8
Prpf38b
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr2_+_155133501 5.037 ENSMUST00000029126.8
ENSMUST00000109685.1
Itch

itchy, E3 ubiquitin protein ligase

chr10_+_13090788 5.036 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr11_+_51263114 5.027 ENSMUST00000093132.6
ENSMUST00000109113.1
Clk4

CDC like kinase 4

chr11_-_62457772 5.014 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 31.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
5.4 21.8 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
4.9 39.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
4.5 22.4 GO:0034421 post-translational protein acetylation(GO:0034421)
4.5 13.4 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
4.4 13.3 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
4.3 13.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
4.1 12.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
4.1 20.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
4.1 20.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
3.9 15.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
3.6 14.5 GO:0070829 heterochromatin maintenance(GO:0070829)
3.5 34.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
3.3 10.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
3.3 3.3 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
3.2 22.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
3.1 9.4 GO:0019858 cytosine metabolic process(GO:0019858)
3.1 9.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
3.0 9.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
3.0 14.9 GO:0046601 positive regulation of centriole replication(GO:0046601)
2.9 5.8 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
2.9 11.6 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.7 10.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
2.7 10.7 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
2.7 8.0 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
2.6 7.9 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
2.6 10.5 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
2.6 10.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
2.6 7.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
2.5 12.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
2.4 9.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
2.3 13.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
2.3 6.8 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
2.3 22.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
2.2 6.7 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
2.2 21.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
2.2 15.1 GO:0030242 pexophagy(GO:0030242)
2.2 8.6 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
2.1 12.6 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
2.1 8.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
2.1 10.3 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
2.0 6.1 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
2.0 5.9 GO:0019085 early viral transcription(GO:0019085)
2.0 5.9 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
1.9 5.8 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
1.9 15.4 GO:0018344 protein geranylgeranylation(GO:0018344)
1.8 5.5 GO:0070650 actin filament bundle distribution(GO:0070650)
1.8 7.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.8 25.6 GO:0060009 Sertoli cell development(GO:0060009)
1.8 10.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.8 5.3 GO:0042275 error-free postreplication DNA repair(GO:0042275)
1.7 15.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.7 5.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.7 5.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.7 5.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
1.7 6.7 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.7 18.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.7 5.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.6 16.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.6 8.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.6 4.8 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
1.5 7.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
1.5 4.5 GO:0019046 release from viral latency(GO:0019046)
1.5 4.4 GO:1990859 cellular response to endothelin(GO:1990859)
1.5 4.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
1.5 4.4 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
1.4 8.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.4 5.7 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.4 11.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
1.4 5.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.4 7.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.4 5.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
1.4 9.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.4 6.9 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
1.3 4.0 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.3 5.3 GO:0097494 regulation of vesicle size(GO:0097494)
1.3 1.3 GO:0071105 response to interleukin-11(GO:0071105)
1.3 18.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.3 2.6 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
1.3 6.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.3 3.8 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.3 7.6 GO:1990928 response to amino acid starvation(GO:1990928)
1.3 3.8 GO:0006407 rRNA export from nucleus(GO:0006407)
1.3 3.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.3 3.8 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
1.3 8.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
1.2 3.7 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.2 7.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
1.2 4.8 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.2 4.8 GO:0045358 germ-line stem cell population maintenance(GO:0030718) negative regulation of interferon-beta biosynthetic process(GO:0045358)
1.2 8.3 GO:0016584 nucleosome positioning(GO:0016584)
1.2 8.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.2 9.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.2 2.3 GO:0006642 triglyceride mobilization(GO:0006642) positive regulation of skeletal muscle cell proliferation(GO:0014858)
1.2 5.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.1 3.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.1 3.4 GO:0010360 negative regulation of anion channel activity(GO:0010360)
1.1 4.5 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.1 3.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
1.1 6.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.1 5.5 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.1 11.9 GO:2000381 negative regulation of mesoderm development(GO:2000381)
1.1 4.3 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
1.1 10.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
1.1 2.1 GO:0048496 maintenance of organ identity(GO:0048496)
1.0 5.2 GO:1903998 regulation of eating behavior(GO:1903998)
1.0 3.1 GO:0045204 MAPK export from nucleus(GO:0045204)
1.0 4.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.0 6.2 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
1.0 14.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.0 4.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.0 5.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.0 6.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
1.0 3.0 GO:0048254 snoRNA localization(GO:0048254)
1.0 6.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
1.0 5.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.0 2.9 GO:0043622 cortical microtubule organization(GO:0043622)
1.0 3.9 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
1.0 9.6 GO:0031053 primary miRNA processing(GO:0031053)
1.0 6.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.0 10.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.9 6.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.9 8.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.9 3.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.9 9.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.9 11.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.9 3.6 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.9 10.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.9 2.6 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.9 6.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 3.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.9 6.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.8 5.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.8 3.3 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.8 7.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.8 2.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.8 5.6 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.8 9.5 GO:0031268 pseudopodium organization(GO:0031268)
0.8 1.6 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.8 2.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.8 8.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.8 4.6 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.8 6.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.8 0.8 GO:0003162 atrioventricular node development(GO:0003162)
0.8 2.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.8 3.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.7 3.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.7 8.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.7 24.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 5.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.7 4.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.7 2.8 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.7 5.6 GO:0015074 DNA integration(GO:0015074)
0.7 13.3 GO:0042119 neutrophil activation(GO:0042119)
0.7 9.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.7 6.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.7 4.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.7 1.4 GO:0048478 replication fork protection(GO:0048478)
0.7 2.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.7 2.0 GO:0043486 histone exchange(GO:0043486)
0.7 14.7 GO:0007099 centriole replication(GO:0007099)
0.7 4.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.7 4.0 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.7 18.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.6 1.9 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.6 2.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.6 1.2 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.6 13.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.6 2.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.6 3.6 GO:0021631 optic nerve morphogenesis(GO:0021631) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.6 4.7 GO:1902065 response to L-glutamate(GO:1902065)
0.6 1.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.6 1.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.6 1.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.6 1.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.6 3.5 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.6 8.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.6 2.9 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.6 4.0 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.6 2.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.6 3.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 2.8 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.6 2.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 6.1 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.6 5.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.6 1.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.5 1.1 GO:0009838 abscission(GO:0009838)
0.5 8.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.5 1.6 GO:0072429 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.5 12.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.5 0.5 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.5 4.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5 3.1 GO:0019985 translesion synthesis(GO:0019985)
0.5 8.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.5 2.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.5 1.6 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.5 4.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.5 9.7 GO:0031297 replication fork processing(GO:0031297)
0.5 4.1 GO:0042118 endothelial cell activation(GO:0042118)
0.5 3.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.5 11.7 GO:0044783 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783)
0.5 2.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.5 5.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.5 10.0 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.5 3.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.5 3.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 7.3 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
0.5 5.5 GO:1990403 embryonic brain development(GO:1990403)
0.4 5.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 1.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 1.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.4 4.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4 2.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 3.9 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.4 0.4 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.4 3.9 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.4 2.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.4 1.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.4 2.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 3.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 5.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.4 2.9 GO:0006551 leucine metabolic process(GO:0006551)
0.4 5.6 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.4 2.8 GO:0014029 neural crest formation(GO:0014029)
0.4 1.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.4 10.1 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
0.4 3.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.4 2.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 3.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.4 4.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.4 1.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 5.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 3.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.4 7.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 0.4 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.4 3.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 1.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.4 7.9 GO:0034453 microtubule anchoring(GO:0034453)
0.4 6.4 GO:0015693 magnesium ion transport(GO:0015693)
0.4 9.2 GO:0006379 mRNA cleavage(GO:0006379)
0.4 0.4 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.4 16.2 GO:0017145 stem cell division(GO:0017145)
0.4 0.4 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.3 5.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.3 3.1 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 3.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 1.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.3 1.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 2.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 2.0 GO:0008343 adult feeding behavior(GO:0008343)
0.3 1.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 1.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.3 1.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 4.7 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.3 3.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.3 2.8 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.3 2.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 10.1 GO:0031648 protein destabilization(GO:0031648)
0.3 3.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 10.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 2.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.3 0.3 GO:0035844 positive regulation of polarized epithelial cell differentiation(GO:0030862) cloaca development(GO:0035844)
0.3 0.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 2.6 GO:0006817 phosphate ion transport(GO:0006817)
0.3 2.0 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 0.8 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.3 5.3 GO:0034508 centromere complex assembly(GO:0034508)
0.3 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 2.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 6.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.3 2.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 3.7 GO:0048520 positive regulation of behavior(GO:0048520)
0.3 0.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 1.0 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.3 3.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 2.6 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.3 6.2 GO:0050684 regulation of mRNA processing(GO:0050684)
0.3 5.4 GO:0060746 parental behavior(GO:0060746)
0.3 1.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 5.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.3 4.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 1.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 29.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.2 1.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 7.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 4.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 5.8 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.2 1.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 11.3 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.2 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.7 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.2 2.6 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 3.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 1.9 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.2 2.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.2 GO:0035622 intrahepatic bile duct development(GO:0035622) common bile duct development(GO:0061009)
0.2 0.5 GO:0048521 negative regulation of behavior(GO:0048521)
0.2 0.7 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.2 3.0 GO:0006907 pinocytosis(GO:0006907)
0.2 1.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 7.2 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.2 2.0 GO:0009301 snRNA transcription(GO:0009301)
0.2 0.4 GO:0097212 lysosomal membrane organization(GO:0097212)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 2.2 GO:0002176 male germ cell proliferation(GO:0002176)
0.2 1.1 GO:0006868 glutamine transport(GO:0006868)
0.2 3.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 2.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 2.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2 5.0 GO:0007020 microtubule nucleation(GO:0007020)
0.2 0.4 GO:0034969 histone arginine methylation(GO:0034969)
0.2 3.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 1.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.2 1.0 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 0.4 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.2 1.0 GO:0045176 apical protein localization(GO:0045176)
0.2 0.4 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 9.3 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.2 5.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 3.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 2.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 0.8 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 2.6 GO:0060416 response to growth hormone(GO:0060416)
0.2 3.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 1.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 0.5 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.2 0.4 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.2 4.7 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.2 GO:0032380 dolichol metabolic process(GO:0019348) regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 6.1 GO:0007492 endoderm development(GO:0007492)
0.2 2.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 0.2 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.2 8.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 0.5 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 1.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.6 GO:0001779 natural killer cell differentiation(GO:0001779)
0.2 2.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.2 6.5 GO:0060612 adipose tissue development(GO:0060612)
0.2 3.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 4.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.2 0.5 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 39.9 GO:0006397 mRNA processing(GO:0006397)
0.1 9.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 4.6 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.1 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.8 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.1 1.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.9 GO:0010869 regulation of receptor biosynthetic process(GO:0010869)
0.1 0.5 GO:0055089 fatty acid homeostasis(GO:0055089)
0.1 3.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.8 GO:0048863 stem cell differentiation(GO:0048863)
0.1 1.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.4 GO:0016598 protein arginylation(GO:0016598)
0.1 3.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.5 GO:1902592 viral budding(GO:0046755) multivesicular body sorting pathway(GO:0071985) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 1.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.9 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.1 2.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 3.0 GO:0003170 heart valve development(GO:0003170)
0.1 1.4 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.8 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 1.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 14.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.5 GO:0033762 response to glucagon(GO:0033762)
0.1 1.3 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.1 0.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.8 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.2 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.1 1.9 GO:0032801 receptor catabolic process(GO:0032801)
0.1 6.7 GO:0046847 filopodium assembly(GO:0046847)
0.1 2.4 GO:0071897 DNA biosynthetic process(GO:0071897)
0.1 1.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 6.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 2.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 1.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.9 GO:0014072 response to isoquinoline alkaloid(GO:0014072)
0.1 0.3 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.2 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 1.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 6.2 GO:0007631 feeding behavior(GO:0007631)
0.1 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.3 GO:0051642 centrosome localization(GO:0051642)
0.1 2.0 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.1 7.2 GO:0007030 Golgi organization(GO:0007030)
0.1 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 1.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.4 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.7 GO:0003016 respiratory system process(GO:0003016)
0.1 1.6 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 2.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 1.3 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 0.5 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.1 1.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.6 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.1 5.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 0.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 1.6 GO:1901998 toxin transport(GO:1901998)
0.1 0.3 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 0.7 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725) negative regulation of NFAT protein import into nucleus(GO:0051534) positive regulation of glycogen metabolic process(GO:0070875)
0.1 4.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.2 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 1.2 GO:0030509 BMP signaling pathway(GO:0030509)
0.1 0.8 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.2 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.1 GO:0000910 cytokinesis(GO:0000910)
0.1 0.2 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 1.4 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 1.0 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 1.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 4.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 1.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.5 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 1.4 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.9 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 1.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.4 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 3.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.7 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 1.4 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.4 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.8 GO:0050890 cognition(GO:0050890)
0.0 1.0 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 21.8 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
4.0 39.5 GO:0000796 condensin complex(GO:0000796)
3.9 11.6 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
3.8 15.0 GO:0044307 dendritic branch(GO:0044307)
3.4 20.4 GO:0098536 deuterosome(GO:0098536)
3.3 13.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
3.2 9.5 GO:0005940 septin ring(GO:0005940)
2.7 19.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
2.6 7.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
2.5 12.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
2.5 7.5 GO:1990047 spindle matrix(GO:1990047)
2.2 4.5 GO:0042585 germinal vesicle(GO:0042585)
2.1 8.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
2.0 6.0 GO:0035061 interchromatin granule(GO:0035061)
2.0 7.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.9 14.9 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
1.8 9.0 GO:0000798 nuclear cohesin complex(GO:0000798)
1.7 8.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.6 14.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.6 16.1 GO:0000805 X chromosome(GO:0000805)
1.5 6.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.5 6.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
1.5 5.9 GO:0070552 BRISC complex(GO:0070552)
1.5 8.9 GO:0097227 sperm annulus(GO:0097227)
1.5 8.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.4 7.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.4 9.7 GO:0001940 male pronucleus(GO:0001940)
1.4 11.0 GO:0097165 nuclear stress granule(GO:0097165)
1.4 11.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
1.3 28.2 GO:0035253 ciliary rootlet(GO:0035253)
1.3 12.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.3 10.3 GO:0042382 paraspeckles(GO:0042382)
1.3 1.3 GO:0098830 presynaptic endosome(GO:0098830)
1.2 3.7 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.2 21.1 GO:0097431 mitotic spindle pole(GO:0097431)
1.2 12.8 GO:0005641 nuclear envelope lumen(GO:0005641)
1.1 4.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.1 10.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.1 13.9 GO:1990635 proximal dendrite(GO:1990635)
1.1 7.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.1 4.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0 6.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
1.0 2.9 GO:0001939 female pronucleus(GO:0001939)
0.9 6.6 GO:0031010 ISWI-type complex(GO:0031010)
0.9 18.8 GO:0016580 Sin3 complex(GO:0016580)
0.9 5.5 GO:0097513 myosin II filament(GO:0097513)
0.9 5.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.9 2.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.9 7.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.9 5.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.9 2.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.9 0.9 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.8 7.6 GO:0071141 SMAD protein complex(GO:0071141)
0.8 2.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.8 1.7 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.8 7.5 GO:0002177 manchette(GO:0002177)
0.8 8.3 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.8 2.5 GO:0035102 PRC1 complex(GO:0035102)
0.8 4.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.8 2.4 GO:0070939 Dsl1p complex(GO:0070939)
0.7 7.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.7 8.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.7 3.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.7 5.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.7 5.7 GO:0031415 NatA complex(GO:0031415)
0.7 14.0 GO:0000242 pericentriolar material(GO:0000242)
0.7 13.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.7 13.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.6 6.4 GO:0001741 XY body(GO:0001741)
0.6 4.4 GO:0071203 WASH complex(GO:0071203)
0.6 4.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 3.0 GO:0072487 MSL complex(GO:0072487)
0.6 2.9 GO:0000235 astral microtubule(GO:0000235)
0.6 5.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 9.9 GO:1904115 axon cytoplasm(GO:1904115)
0.6 2.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.6 7.4 GO:0005686 U2 snRNP(GO:0005686)
0.6 17.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.6 4.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 4.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.6 3.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.6 7.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.6 2.8 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.6 3.9 GO:0070187 telosome(GO:0070187)
0.6 19.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.6 9.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 1.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.5 6.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.5 2.2 GO:0001652 granular component(GO:0001652)
0.5 4.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 2.1 GO:0032021 NELF complex(GO:0032021)
0.5 5.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 1.4 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.4 1.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 4.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.4 3.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 8.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.4 36.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.4 3.5 GO:0030478 actin cap(GO:0030478)
0.4 18.5 GO:0005871 kinesin complex(GO:0005871)
0.4 2.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 19.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 6.2 GO:0051286 cell tip(GO:0051286)
0.4 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.3 2.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 2.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.3 1.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 4.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 4.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 10.5 GO:0005876 spindle microtubule(GO:0005876)
0.3 4.6 GO:0017119 Golgi transport complex(GO:0017119)
0.3 6.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 5.8 GO:0035371 microtubule plus-end(GO:0035371)
0.3 3.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 1.2 GO:0000974 Prp19 complex(GO:0000974)
0.3 2.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.5 GO:0030314 junctional membrane complex(GO:0030314)
0.3 4.6 GO:0032039 integrator complex(GO:0032039)
0.3 2.9 GO:0031011 Ino80 complex(GO:0031011)
0.3 2.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 4.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 5.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 3.9 GO:0035861 site of double-strand break(GO:0035861)
0.3 2.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 3.9 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.3 1.6 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3 1.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 15.5 GO:0000922 spindle pole(GO:0000922)
0.3 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 3.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 36.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 21.4 GO:0005681 spliceosomal complex(GO:0005681)
0.2 6.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 6.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 1.1 GO:0000346 transcription export complex(GO:0000346)
0.2 1.1 GO:0090543 Flemming body(GO:0090543)
0.2 3.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 7.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 10.1 GO:0043034 costamere(GO:0043034)
0.2 6.7 GO:0000791 euchromatin(GO:0000791)
0.2 3.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 0.8 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.2 2.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.7 GO:0061700 GATOR2 complex(GO:0061700)
0.2 11.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.2 5.6 GO:0044815 DNA packaging complex(GO:0044815)
0.2 1.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.2 9.8 GO:0000502 proteasome complex(GO:0000502)
0.2 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 7.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 14.1 GO:0016605 PML body(GO:0016605)
0.2 3.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 53.9 GO:0000785 chromatin(GO:0000785)
0.2 3.7 GO:0043596 nuclear replication fork(GO:0043596)
0.2 0.5 GO:0031417 NatC complex(GO:0031417)
0.1 4.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 10.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 1.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 61.9 GO:0016604 nuclear body(GO:0016604)
0.1 7.7 GO:0005814 centriole(GO:0005814)
0.1 6.3 GO:0005643 nuclear pore(GO:0005643)
0.1 0.5 GO:0060053 H zone(GO:0031673) neurofilament cytoskeleton(GO:0060053)
0.1 6.6 GO:0005811 lipid particle(GO:0005811)
0.1 1.8 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 6.1 GO:0016459 myosin complex(GO:0016459)
0.1 1.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 19.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 2.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 7.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 3.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.2 GO:0070938 contractile ring(GO:0070938)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 4.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 3.4 GO:0031941 filamentous actin(GO:0031941)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 15.4 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 1.0 GO:0030133 transport vesicle(GO:0030133)
0.1 0.7 GO:0044292 dendrite terminus(GO:0044292) dendritic growth cone(GO:0044294)
0.1 3.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.7 GO:0097546 ciliary base(GO:0097546)
0.1 18.8 GO:0005815 microtubule organizing center(GO:0005815)
0.1 5.7 GO:0005694 chromosome(GO:0005694)
0.1 9.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.4 GO:0070820 tertiary granule(GO:0070820)
0.1 9.3 GO:0044306 neuron projection terminus(GO:0044306)
0.1 4.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.4 GO:0034702 ion channel complex(GO:0034702)
0.1 3.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 6.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 8.3 GO:0005874 microtubule(GO:0005874)
0.1 3.7 GO:0072562 blood microparticle(GO:0072562)
0.1 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 4.8 GO:0001650 fibrillar center(GO:0001650)
0.1 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 7.3 GO:0030426 growth cone(GO:0030426)
0.1 1.5 GO:0044439 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 2.4 GO:0005938 cell cortex(GO:0005938)
0.0 5.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 45.1 GO:0005654 nucleoplasm(GO:0005654)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.0 GO:0045202 synapse(GO:0045202)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.6 GO:0043292 contractile fiber(GO:0043292)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 6.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 28.8 GO:0001069 regulatory region RNA binding(GO:0001069)
4.3 13.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
3.6 10.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
3.5 24.6 GO:0099609 microtubule lateral binding(GO:0099609)
3.2 19.2 GO:0097016 L27 domain binding(GO:0097016)
3.1 21.8 GO:0015616 DNA translocase activity(GO:0015616)
3.1 21.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.0 9.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
2.9 11.6 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.6 18.5 GO:0033592 RNA strand annealing activity(GO:0033592)
2.5 7.6 GO:0035500 MH2 domain binding(GO:0035500)
2.3 11.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
2.3 6.8 GO:0004774 succinate-CoA ligase activity(GO:0004774)
2.2 11.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
2.2 8.8 GO:0036033 mediator complex binding(GO:0036033)
2.0 5.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.0 5.9 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.9 7.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.7 8.7 GO:0035174 histone serine kinase activity(GO:0035174)
1.7 22.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.7 10.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.7 10.0 GO:0097001 ceramide binding(GO:0097001)
1.6 4.9 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
1.4 9.6 GO:0061665 SUMO ligase activity(GO:0061665)
1.4 14.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.3 10.7 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.3 4.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
1.3 10.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.3 7.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.3 28.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.3 2.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.3 7.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.2 8.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.2 7.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.2 4.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.2 2.3 GO:0001129 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
1.1 8.9 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
1.1 9.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.1 10.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.0 8.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.0 4.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.0 3.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.0 2.9 GO:0071568 UFM1 transferase activity(GO:0071568)
0.9 7.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.9 3.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.9 9.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.9 0.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.9 6.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.9 5.1 GO:0034046 poly(G) binding(GO:0034046)
0.9 2.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.8 4.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.8 8.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.8 4.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.8 2.4 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.8 22.9 GO:0070840 dynein complex binding(GO:0070840)
0.8 4.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.8 1.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.8 2.3 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.8 9.3 GO:0044548 S100 protein binding(GO:0044548)
0.8 6.2 GO:0030911 TPR domain binding(GO:0030911)
0.8 6.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 4.3 GO:0070728 leucine binding(GO:0070728)
0.7 5.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.7 2.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.7 4.0 GO:0033142 progesterone receptor binding(GO:0033142)
0.7 2.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.7 2.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.7 5.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.7 23.4 GO:0017091 AU-rich element binding(GO:0017091)
0.6 3.2 GO:0034452 dynactin binding(GO:0034452)
0.6 33.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.6 2.6 GO:1990460 leptin receptor binding(GO:1990460)
0.6 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.6 11.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 1.8 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.6 30.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.6 4.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.6 2.3 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.6 2.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.6 1.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.6 8.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 2.7 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.5 10.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.5 3.0 GO:0045545 syndecan binding(GO:0045545)
0.5 5.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 33.9 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.5 5.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.5 2.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.5 5.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 2.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 15.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.5 5.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.5 37.1 GO:0003777 microtubule motor activity(GO:0003777)
0.4 18.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.4 2.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 0.4 GO:0019003 GDP binding(GO:0019003)
0.4 4.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 2.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.4 10.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.4 7.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.4 11.0 GO:0070064 proline-rich region binding(GO:0070064)
0.4 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.4 19.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.4 1.6 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.4 7.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4 7.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 7.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 7.7 GO:0070410 co-SMAD binding(GO:0070410)
0.4 3.0 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.4 1.9 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.4 5.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 8.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.4 10.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 12.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.4 7.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 10.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 10.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 9.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 6.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 5.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 4.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 6.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 9.6 GO:0051018 protein kinase A binding(GO:0051018)
0.3 29.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 13.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 4.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 1.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 2.9 GO:1990405 protein antigen binding(GO:1990405)
0.3 5.1 GO:0005521 lamin binding(GO:0005521)
0.3 6.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 7.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 1.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 22.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 1.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3 4.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 6.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 2.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 0.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 4.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 1.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 8.1 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.2 0.7 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 66.1 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.2 2.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 2.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.2 1.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 0.7 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.2 16.2 GO:0032947 protein complex scaffold(GO:0032947)
0.2 5.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 2.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 3.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.9 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 5.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 40.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 3.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 9.6 GO:0035064 methylated histone binding(GO:0035064)
0.2 2.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 2.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 3.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 6.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.6 GO:0031005 filamin binding(GO:0031005)
0.2 0.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 6.4 GO:0002039 p53 binding(GO:0002039)
0.2 2.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 9.3 GO:0030507 spectrin binding(GO:0030507)
0.2 4.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 3.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 5.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 3.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 66.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 27.8 GO:0008017 microtubule binding(GO:0008017)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 4.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 2.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 58.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 5.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 1.4 GO:0031489 myosin V binding(GO:0031489)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 7.8 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 8.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0048156 tau protein binding(GO:0048156)
0.1 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 2.3 GO:0008483 transaminase activity(GO:0008483)
0.1 4.4 GO:0004386 helicase activity(GO:0004386)
0.1 6.9 GO:0043130 ubiquitin binding(GO:0043130)
0.1 7.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 4.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 3.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 3.4 GO:0005109 frizzled binding(GO:0005109)
0.1 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.9 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 60.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 1.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.5 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.1 5.9 GO:0042393 histone binding(GO:0042393)
0.1 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.6 GO:0008198 ferrous iron binding(GO:0008198)
0.1 4.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 1.7 GO:0043022 ribosome binding(GO:0043022)
0.1 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 1.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 0.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 5.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 4.3 GO:0051015 actin filament binding(GO:0051015)
0.1 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 10.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 25.0 GO:0003677 DNA binding(GO:0003677)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 6.0 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 7.8 GO:0005525 GTP binding(GO:0005525)
0.0 1.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.6 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 69.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.8 11.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.6 14.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6 15.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.6 36.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.6 13.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.6 24.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.5 20.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.5 10.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.4 38.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.4 16.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.4 21.7 PID_PLK1_PATHWAY PLK1 signaling events
0.4 13.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.3 14.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 6.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.3 11.8 PID_ATM_PATHWAY ATM pathway
0.3 6.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 13.2 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.3 1.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 2.0 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.2 4.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 4.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 2.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.7 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.2 3.8 PID_CDC42_PATHWAY CDC42 signaling events
0.2 4.3 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.2 1.5 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.2 4.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.2 4.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 8.1 PID_E2F_PATHWAY E2F transcription factor network
0.1 6.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 4.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 1.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 2.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.4 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 2.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 3.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 2.9 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 6.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.0 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 1.3 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 9.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.7 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.0 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 4.5 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.0 2.0 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
1.9 50.7 REACTOME_KINESINS Genes involved in Kinesins
1.2 67.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.1 15.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.0 31.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
1.0 17.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.9 48.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.9 37.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.8 3.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.8 20.2 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.7 4.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.7 11.9 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7 6.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 16.0 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.6 6.9 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.6 9.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 20.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.5 6.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.4 5.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 8.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.4 32.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 18.4 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.4 12.6 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.4 11.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4 10.8 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.3 5.9 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 4.0 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3 2.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 28.3 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.3 4.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 4.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 2.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 5.9 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 7.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.3 3.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.3 3.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.2 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 5.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 5.0 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 5.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 4.7 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 3.6 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 2.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 11.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 1.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 1.1 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.2 5.1 REACTOME_CHROMOSOME_MAINTENANCE Genes involved in Chromosome Maintenance
0.2 2.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.6 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 7.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 5.7 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 5.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.4 REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.2 5.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 1.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 1.7 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 4.0 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 6.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 2.0 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 4.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.1 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 3.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.0 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 3.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.8 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.1 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.8 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 6.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 4.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.6 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.1 3.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.1 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.1 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.1 1.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.8 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.2 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 6.1 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.0 REACTOME_CD28_CO_STIMULATION Genes involved in CD28 co-stimulation