Motif ID: Tal1

Z-value: 0.736


Transcription factors associated with Tal1:

Gene SymbolEntrez IDGene Name
Tal1 ENSMUSG00000028717.6 Tal1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tal1mm10_v2_chr4_+_115059507_1150595530.305.9e-02Click!


Activity profile for motif Tal1.

activity profile for motif Tal1


Sorted Z-values histogram for motif Tal1

Sorted Z-values for motif Tal1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tal1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103853199 6.194 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr11_+_32276400 3.440 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr6_+_17306335 3.243 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr8_-_71511762 3.136 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr11_+_32276893 3.040 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr2_+_180499893 2.999 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr17_-_29237759 2.058 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr10_+_97565436 1.855 ENSMUST00000038160.4
Lum
lumican
chr8_-_71537402 1.805 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr11_+_94936224 1.622 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr10_+_116177351 1.568 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr19_+_42247544 1.565 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr5_-_105139539 1.560 ENSMUST00000100961.4
ENSMUST00000031235.6
ENSMUST00000100962.3
Gbp9
Gbp8
Gbp4
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr16_-_18621366 1.374 ENSMUST00000051160.2
Gp1bb
glycoprotein Ib, beta polypeptide
chr6_+_17306415 1.332 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr8_-_125898291 1.317 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr5_-_105239533 1.266 ENSMUST00000065588.6
Gbp10
guanylate-binding protein 10
chr10_-_62342674 1.250 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr6_-_72235559 1.237 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr15_+_60822947 1.227 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr2_-_153225396 1.213 ENSMUST00000099194.2
Tspyl3
TSPY-like 3
chr9_-_111057235 1.191 ENSMUST00000111888.1
Ccrl2
chemokine (C-C motif) receptor-like 2
chr6_+_86078070 1.165 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr7_+_119900099 1.125 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr18_-_36726730 1.082 ENSMUST00000061829.6
Cd14
CD14 antigen
chr8_-_36732897 1.076 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr5_-_5265224 1.046 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr2_-_149798701 1.008 ENSMUST00000148202.1
ENSMUST00000139471.1
Gm14133

predicted gene 14133

chr12_+_103434211 0.970 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr1_-_162866502 0.965 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr5_-_105110292 0.958 ENSMUST00000031238.6
Gbp9
guanylate-binding protein 9
chr5_-_105293699 0.920 ENSMUST00000050011.8
Gbp6
guanylate binding protein 6
chr7_+_97842917 0.902 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr4_+_41465134 0.888 ENSMUST00000030154.6
Nudt2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr19_-_7206234 0.828 ENSMUST00000123594.1
ENSMUST00000025679.4
Otub1

OTU domain, ubiquitin aldehyde binding 1

chr10_-_11082287 0.818 ENSMUST00000105561.2
ENSMUST00000044306.6
Grm1

glutamate receptor, metabotropic 1

chr8_-_77517898 0.818 ENSMUST00000076316.4
Arhgap10
Rho GTPase activating protein 10
chr15_+_89568322 0.816 ENSMUST00000023295.2
Acr
acrosin prepropeptide
chrX_-_107403295 0.811 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr3_+_79885930 0.796 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr5_-_24351604 0.774 ENSMUST00000036092.7
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr10_+_40883469 0.771 ENSMUST00000019975.7
Wasf1
WAS protein family, member 1
chr3_+_79884576 0.744 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr19_+_20601958 0.730 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr5_-_103911196 0.708 ENSMUST00000031254.2
Klhl8
kelch-like 8
chr2_-_79908428 0.689 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr3_-_33083016 0.684 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr1_-_132367879 0.682 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr9_-_32541589 0.660 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr13_+_55593135 0.658 ENSMUST00000109905.3
Tmed9
transmembrane emp24 protein transport domain containing 9
chr3_+_79884496 0.631 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr2_-_102901346 0.630 ENSMUST00000111192.2
ENSMUST00000111190.2
ENSMUST00000111198.2
ENSMUST00000111191.2
ENSMUST00000060516.7
ENSMUST00000099673.2
ENSMUST00000005218.8
ENSMUST00000111194.1
Cd44







CD44 antigen







chr2_-_79908389 0.626 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr9_+_107950952 0.625 ENSMUST00000049348.3
Traip
TRAF-interacting protein
chr19_-_19111181 0.620 ENSMUST00000112832.1
Rorb
RAR-related orphan receptor beta
chr9_+_57998036 0.616 ENSMUST00000181289.1
Gm17322
predicted gene, 17322
chr8_+_3587445 0.606 ENSMUST00000057028.7
ENSMUST00000171962.1
Camsap3

calmodulin regulated spectrin-associated protein family, member 3

chr1_+_169969409 0.594 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr12_-_72664759 0.589 ENSMUST00000021512.9
Dhrs7
dehydrogenase/reductase (SDR family) member 7
chr7_+_99594605 0.589 ENSMUST00000162290.1
Arrb1
arrestin, beta 1
chr19_+_31082841 0.582 ENSMUST00000066039.6
Cstf2t
cleavage stimulation factor, 3' pre-RNA subunit 2, tau
chr7_+_126760591 0.539 ENSMUST00000091328.2
Mapk3
mitogen-activated protein kinase 3
chr9_+_108290433 0.539 ENSMUST00000035227.6
Nicn1
nicolin 1
chr11_+_50225315 0.531 ENSMUST00000041725.7
Mgat4b
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr7_+_16875302 0.525 ENSMUST00000108493.1
Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr7_-_139582790 0.525 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr6_+_30541582 0.498 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr2_-_153015331 0.492 ENSMUST00000028972.8
Pdrg1
p53 and DNA damage regulated 1
chr2_-_6722187 0.491 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr13_-_66227573 0.476 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr11_+_58948890 0.473 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr11_+_4986824 0.465 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr1_+_163779575 0.462 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr10_-_39133914 0.460 ENSMUST00000135785.1
Fam229b
family with sequence similarity 229, member B
chr2_+_127080252 0.435 ENSMUST00000142737.1
Blvra
biliverdin reductase A
chr7_-_44375006 0.434 ENSMUST00000107933.1
1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr4_+_138304723 0.433 ENSMUST00000030538.4
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
chr19_+_29367447 0.426 ENSMUST00000016640.7
Cd274
CD274 antigen
chr1_+_180851131 0.425 ENSMUST00000038091.6
Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr11_+_78115565 0.411 ENSMUST00000155571.1
Fam222b
family with sequence similarity 222, member B
chr2_+_5137756 0.402 ENSMUST00000027988.7
Ccdc3
coiled-coil domain containing 3
chr14_+_55560480 0.380 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr19_+_24875679 0.379 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr9_-_22002599 0.367 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151

coiled-coil domain containing 151

chr17_-_24886304 0.363 ENSMUST00000044252.5
Nubp2
nucleotide binding protein 2
chr15_-_83170498 0.353 ENSMUST00000162178.1
Cyb5r3
cytochrome b5 reductase 3
chr1_+_88134786 0.333 ENSMUST00000113134.1
ENSMUST00000140092.1
Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr6_+_47877204 0.327 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr7_-_105633479 0.321 ENSMUST00000147044.1
ENSMUST00000106791.1
Trim3

tripartite motif-containing 3

chr9_-_21963568 0.315 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr19_-_29367294 0.308 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr11_-_102469839 0.301 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr5_-_107972864 0.296 ENSMUST00000153172.1
Fam69a
family with sequence similarity 69, member A
chr8_-_105938384 0.295 ENSMUST00000034369.8
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr10_-_117224480 0.292 ENSMUST00000020382.6
Yeats4
YEATS domain containing 4
chr4_+_134864536 0.291 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr7_+_110773658 0.287 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr6_+_68161415 0.280 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr15_+_78926720 0.279 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr2_-_6721890 0.267 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr1_+_109983006 0.265 ENSMUST00000145188.1
Cdh7
cadherin 7, type 2
chr17_+_34981847 0.257 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_59438633 0.255 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr7_+_101317073 0.250 ENSMUST00000163799.2
ENSMUST00000164479.2
Stard10

START domain containing 10

chr11_+_65807175 0.250 ENSMUST00000071465.2
ENSMUST00000018491.7
Zkscan6

zinc finger with KRAB and SCAN domains 6

chrX_-_8193387 0.233 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp

phenylalkylamine Ca2+ antagonist (emopamil) binding protein

chr3_+_133338936 0.231 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr8_-_83594440 0.229 ENSMUST00000019382.9
ENSMUST00000165740.1
Tecr

trans-2,3-enoyl-CoA reductase

chr2_+_136891501 0.227 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr15_+_99393574 0.215 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr7_-_79594924 0.215 ENSMUST00000172788.1
Rhcg
Rhesus blood group-associated C glycoprotein
chr15_-_83170168 0.205 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chr13_+_90089705 0.203 ENSMUST00000012566.8
Tmem167
transmembrane protein 167
chr14_+_55560904 0.195 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr19_-_46969474 0.184 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr13_-_90089513 0.174 ENSMUST00000160232.1
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr1_+_88103229 0.167 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr17_+_36869567 0.165 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr15_+_99393610 0.162 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr2_+_136892168 0.156 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr5_-_134176720 0.153 ENSMUST00000076228.2
Wbscr16
Williams-Beuren syndrome chromosome region 16 homolog (human)
chr4_-_56802265 0.153 ENSMUST00000030140.2
Ikbkap
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr7_-_126898249 0.148 ENSMUST00000121532.1
ENSMUST00000032926.5
Tmem219

transmembrane protein 219

chr12_-_81594958 0.145 ENSMUST00000002756.7
ENSMUST00000161598.1
ENSMUST00000161211.1
Med6


mediator of RNA polymerase II transcription, subunit 6 homolog (yeast)


chr13_+_98263242 0.142 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr8_+_107436355 0.138 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr3_+_89136133 0.131 ENSMUST00000047111.6
Pklr
pyruvate kinase liver and red blood cell
chr6_-_34317442 0.129 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr14_+_55561060 0.125 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr9_-_60688118 0.118 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr7_-_99238564 0.117 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr18_+_37484955 0.097 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr5_+_138280516 0.093 ENSMUST00000048028.8
Stag3
stromal antigen 3
chrX_+_56447965 0.093 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chrX_+_7579666 0.091 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr6_-_126645784 0.086 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr5_+_24393640 0.083 ENSMUST00000138168.1
ENSMUST00000115077.1
Abcb8

ATP-binding cassette, sub-family B (MDR/TAP), member 8

chr14_+_44102654 0.076 ENSMUST00000074839.6
Ear2
eosinophil-associated, ribonuclease A family, member 2
chr13_+_49682100 0.074 ENSMUST00000165316.1
ENSMUST00000047363.7
Iars

isoleucine-tRNA synthetase

chr5_+_138280538 0.073 ENSMUST00000162245.1
ENSMUST00000161691.1
Stag3

stromal antigen 3

chr2_+_76369967 0.056 ENSMUST00000046389.4
Rbm45
RNA binding motif protein 45
chr4_-_118179628 0.053 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr11_-_98625661 0.052 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr3_+_97628804 0.045 ENSMUST00000107050.1
ENSMUST00000029729.8
ENSMUST00000107049.1
Fmo5


flavin containing monooxygenase 5


chr17_-_33713372 0.043 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr5_-_121836810 0.042 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr14_-_43819639 0.035 ENSMUST00000100691.3
Ear1
eosinophil-associated, ribonuclease A family, member 1
chr2_+_85037448 0.027 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr8_+_80494032 0.021 ENSMUST00000063359.6
Gypa
glycophorin A
chr10_-_128626464 0.018 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr12_-_81485073 0.015 ENSMUST00000166723.1
ENSMUST00000110340.2
ENSMUST00000168463.1
ENSMUST00000169124.1
ENSMUST00000002757.4
Cox16




cytochrome c oxidase assembly protein 16




chr1_-_52232296 0.011 ENSMUST00000114512.1
Gls
glutaminase
chr4_-_118180043 0.010 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr17_+_40811089 0.008 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chrX_-_134111852 0.005 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr7_-_18992774 0.004 ENSMUST00000098778.2
Gm10676
predicted gene 10676
chr4_+_132535542 0.003 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr9_-_65827544 0.002 ENSMUST00000159109.1
Zfp609
zinc finger protein 609
chrX_+_93675088 0.001 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.7 GO:0015671 oxygen transport(GO:0015671)
0.9 4.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7 3.0 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.5 1.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.5 1.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.4 1.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 0.9 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 0.8 GO:0007341 penetration of zona pellucida(GO:0007341)
0.3 1.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 1.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 3.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.2 4.7 GO:0042832 defense response to protozoan(GO:0042832)
0.2 0.7 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 0.6 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.2 0.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 1.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.8 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.0 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.9 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.7 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.5 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 2.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.0 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.1 1.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.4 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.4 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.8 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 12.7 GO:0005833 hemoglobin complex(GO:0005833)
0.7 3.0 GO:0032280 symmetric synapse(GO:0032280)
0.5 1.6 GO:0005584 collagen type I trimer(GO:0005584)
0.4 4.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 3.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.2 1.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.5 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 1.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.9 GO:0071437 invadopodium(GO:0071437)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 0.8 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0000802 transverse filament(GO:0000802)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 4.2 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.9 4.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 1.1 GO:0071723 lipopeptide binding(GO:0071723)
0.2 1.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.8 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 3.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.4 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.3 GO:0005534 galactose binding(GO:0005534)
0.1 1.1 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.8 GO:0005537 mannose binding(GO:0005537)
0.1 1.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 0.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.6 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 4.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.9 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 0.7 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 1.1 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.6 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.4 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 0.9 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.0 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.5 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 1.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.2 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters