Motif ID: Tbr1

Z-value: 0.803


Transcription factors associated with Tbr1:

Gene SymbolEntrez IDGene Name
Tbr1 ENSMUSG00000035033.9 Tbr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbr1mm10_v2_chr2_+_61804453_61804538-0.518.8e-04Click!


Activity profile for motif Tbr1.

activity profile for motif Tbr1


Sorted Z-values histogram for motif Tbr1

Sorted Z-values for motif Tbr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_85473883 3.250 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chrY_+_897782 2.665 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr5_+_111733924 2.299 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr7_-_46672537 2.131 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr12_-_113422730 2.042 ENSMUST00000177715.1
ENSMUST00000103426.1
Ighm

immunoglobulin heavy constant mu

chr17_+_34263209 1.830 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr1_-_186705980 1.787 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr9_+_53850243 1.695 ENSMUST00000048485.5
Sln
sarcolipin
chr7_+_30413744 1.639 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr3_+_95526777 1.564 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr7_-_19698206 1.560 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr15_+_79891631 1.505 ENSMUST00000177350.1
ENSMUST00000177483.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr19_-_57008187 1.493 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr4_-_109665249 1.389 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr2_-_114052804 1.353 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr11_-_32222233 1.310 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr11_-_84068766 1.299 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr12_-_113307912 1.281 ENSMUST00000103418.1
Ighg2b
immunoglobulin heavy constant gamma 2B
chr8_+_45885479 1.251 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr13_-_105271039 1.225 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr12_-_113260217 1.218 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr3_+_94693556 1.217 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr11_-_69900930 1.192 ENSMUST00000018714.6
ENSMUST00000128046.1
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr11_+_32283511 1.165 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr9_+_3025417 1.149 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr11_+_32296489 1.146 ENSMUST00000093207.3
Hba-a2
hemoglobin alpha, adult chain 2
chr4_-_154636831 1.121 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr16_-_43979050 1.101 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr5_+_64812336 1.084 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr9_-_124493793 1.076 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr14_-_19418930 1.068 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr4_-_134095078 1.062 ENSMUST00000000696.6
Cd52
CD52 antigen
chr12_+_84069325 1.062 ENSMUST00000046422.4
ENSMUST00000072505.4
Acot5

acyl-CoA thioesterase 5

chr2_+_103970115 1.058 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr8_+_120736352 1.020 ENSMUST00000047737.3
ENSMUST00000162658.1
Irf8

interferon regulatory factor 8

chr11_-_69900949 1.015 ENSMUST00000102580.3
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr18_+_5591860 0.987 ENSMUST00000025081.5
ENSMUST00000159390.1
Zeb1

zinc finger E-box binding homeobox 1

chr10_+_57784859 0.986 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr15_-_58034289 0.981 ENSMUST00000100655.3
9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr17_+_57358682 0.966 ENSMUST00000086763.5
ENSMUST00000004850.7
Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr2_-_91931675 0.957 ENSMUST00000111309.1
Mdk
midkine
chr18_+_84088077 0.956 ENSMUST00000060223.2
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr2_-_91931774 0.936 ENSMUST00000069423.6
Mdk
midkine
chr1_-_171059390 0.933 ENSMUST00000164044.1
ENSMUST00000169017.1
Fcgr3

Fc receptor, IgG, low affinity III

chr5_+_113490447 0.912 ENSMUST00000094452.3
Wscd2
WSC domain containing 2
chr11_-_69900886 0.908 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr3_-_89393294 0.907 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr11_+_82035569 0.898 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr2_-_91931696 0.896 ENSMUST00000090602.5
Mdk
midkine
chr17_+_87635974 0.892 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr9_-_21760275 0.889 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_+_62292475 0.874 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr1_-_191183244 0.873 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr19_+_55894508 0.870 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr7_-_132813799 0.865 ENSMUST00000097998.2
Fam53b
family with sequence similarity 53, member B
chr16_+_10812915 0.859 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr16_-_44027938 0.835 ENSMUST00000114677.1
Gramd1c
GRAM domain containing 1C
chr6_+_4504814 0.833 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr5_+_64092925 0.819 ENSMUST00000087324.5
Pgm1
phosphoglucomutase 1
chr11_-_84068357 0.818 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr5_+_91517615 0.815 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr4_-_32923455 0.813 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr7_-_19573379 0.803 ENSMUST00000119912.1
Gemin7
gem (nuclear organelle) associated protein 7
chr15_-_83033294 0.799 ENSMUST00000100377.4
Nfam1
Nfat activating molecule with ITAM motif 1
chr7_-_127993831 0.798 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chr6_+_141249161 0.798 ENSMUST00000043259.7
Pde3a
phosphodiesterase 3A, cGMP inhibited
chr14_-_31640878 0.797 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr3_+_94933041 0.774 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr15_+_99601372 0.748 ENSMUST00000023754.5
Aqp6
aquaporin 6
chr2_-_169405435 0.747 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr11_+_3514861 0.745 ENSMUST00000094469.4
Selm
selenoprotein M
chr3_-_116968827 0.744 ENSMUST00000119557.1
Palmd
palmdelphin
chr15_+_79892436 0.725 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr1_-_155527083 0.715 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr4_+_59626189 0.707 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr7_-_105787567 0.706 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr18_-_36726730 0.702 ENSMUST00000061829.6
Cd14
CD14 antigen
chr4_-_42084291 0.701 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr7_-_132813528 0.698 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr15_+_79892397 0.688 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr6_+_134929089 0.688 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr6_+_138140298 0.685 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr7_-_132813715 0.681 ENSMUST00000134946.1
Fam53b
family with sequence similarity 53, member B
chr15_+_83526854 0.672 ENSMUST00000016902.3
Bik
BCL2-interacting killer
chr2_+_84980458 0.671 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr4_+_117849193 0.666 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr8_-_84662841 0.665 ENSMUST00000060427.4
Ier2
immediate early response 2
chr11_-_6274830 0.663 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chr16_-_37384915 0.663 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr14_+_60732906 0.661 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr2_+_103970221 0.661 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr4_-_42168603 0.658 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr9_-_106199253 0.648 ENSMUST00000140761.1
Ppm1m
protein phosphatase 1M
chr6_+_48647224 0.648 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr6_+_134929118 0.646 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr14_-_64455903 0.644 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr3_-_66296807 0.643 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr11_+_83662579 0.638 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chr7_+_27486910 0.637 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chrX_+_100625737 0.635 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr15_+_79347534 0.634 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr3_-_84220853 0.631 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr2_-_160619971 0.624 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr3_-_115715031 0.624 ENSMUST00000055676.2
S1pr1
sphingosine-1-phosphate receptor 1
chr10_+_20347788 0.622 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr14_+_80000292 0.616 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr7_-_37770757 0.610 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr16_+_44867097 0.609 ENSMUST00000102805.3
Cd200r2
Cd200 receptor 2
chr19_-_10881723 0.606 ENSMUST00000144681.1
Tmem109
transmembrane protein 109
chr4_+_148130883 0.605 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr6_+_68161415 0.602 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr4_-_42581621 0.602 ENSMUST00000178742.1
Gm10592
predicted gene 10592
chr7_-_80688852 0.601 ENSMUST00000122255.1
Crtc3
CREB regulated transcription coactivator 3
chr3_+_90514435 0.600 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr1_+_164115264 0.596 ENSMUST00000162746.1
Selp
selectin, platelet
chr7_-_42578588 0.594 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr12_-_87775755 0.593 ENSMUST00000164517.2
Gm21319
predicted gene, 21319
chr4_-_42773993 0.593 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr10_+_57784914 0.592 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr7_-_126625676 0.591 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr2_-_60963192 0.588 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr1_-_192855723 0.584 ENSMUST00000155579.1
Sertad4
SERTA domain containing 4
chr19_+_37436707 0.572 ENSMUST00000128184.1
Hhex
hematopoietically expressed homeobox
chr13_+_112464070 0.571 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
Il6st


interleukin 6 signal transducer


chr16_-_37384940 0.567 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr9_-_43239816 0.565 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr9_-_122294361 0.564 ENSMUST00000042546.2
Ano10
anoctamin 10
chr8_-_80057989 0.562 ENSMUST00000079038.2
Hhip
Hedgehog-interacting protein
chr2_-_32741016 0.556 ENSMUST00000009695.2
6330409D20Rik
RIKEN cDNA 6330409D20 gene
chr2_+_144270900 0.547 ENSMUST00000028910.2
ENSMUST00000110027.1
Mgme1

mitochondrial genome maintainance exonuclease 1

chr6_-_86765807 0.546 ENSMUST00000123732.1
Anxa4
annexin A4
chr17_+_6978860 0.536 ENSMUST00000089119.5
ENSMUST00000179728.1
Rnaset2b

ribonuclease T2B

chr19_+_6950746 0.535 ENSMUST00000145463.1
Bad
BCL2-associated agonist of cell death
chr8_+_57511833 0.535 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr7_-_130573118 0.532 ENSMUST00000159694.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr1_-_138847579 0.530 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr10_+_26229707 0.526 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr8_-_115707778 0.525 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr1_+_132191436 0.522 ENSMUST00000112357.2
Lemd1
LEM domain containing 1
chrX_+_99003224 0.520 ENSMUST00000149999.1
Stard8
START domain containing 8
chr10_+_60346851 0.518 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
4632428N05Rik


RIKEN cDNA 4632428N05 gene


chr7_-_99695809 0.517 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr3_-_88369730 0.512 ENSMUST00000075523.4
Bglap3
bone gamma-carboxyglutamate protein 3
chr2_-_33942111 0.511 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr11_-_84068554 0.508 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr5_-_122002340 0.507 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr9_+_73044833 0.503 ENSMUST00000184146.1
ENSMUST00000034722.4
Rab27a

RAB27A, member RAS oncogene family

chr7_-_16259185 0.502 ENSMUST00000168818.1
C5ar1
complement component 5a receptor 1
chr1_-_53785214 0.502 ENSMUST00000027263.7
Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr3_+_107896247 0.501 ENSMUST00000169365.1
Gstm5
glutathione S-transferase, mu 5
chr6_+_7555053 0.501 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr4_+_62668864 0.499 ENSMUST00000124082.1
Rgs3
regulator of G-protein signaling 3
chr5_+_31094984 0.498 ENSMUST00000066505.1
Gm9924
predicted gene 9924
chr11_+_119913423 0.497 ENSMUST00000132197.1
Chmp6
charged multivesicular body protein 6
chr8_-_41016749 0.495 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr8_-_122476036 0.494 ENSMUST00000014614.3
Rnf166
ring finger protein 166
chr14_+_31641051 0.492 ENSMUST00000090147.6
Btd
biotinidase
chr16_-_57754707 0.492 ENSMUST00000089332.4
Col8a1
collagen, type VIII, alpha 1
chr17_-_73950172 0.490 ENSMUST00000024866.4
Xdh
xanthine dehydrogenase
chr6_-_86765866 0.485 ENSMUST00000113675.1
Anxa4
annexin A4
chr14_+_47373813 0.484 ENSMUST00000142734.1
ENSMUST00000150290.1
ENSMUST00000144794.1
ENSMUST00000146468.1
Lgals3



lectin, galactose binding, soluble 3



chr6_+_29433131 0.482 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr4_-_132510493 0.480 ENSMUST00000030724.8
Sesn2
sestrin 2
chr7_-_105787544 0.470 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr16_-_95459245 0.468 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr11_+_114851507 0.467 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr4_-_149774238 0.458 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr9_-_46319984 0.454 ENSMUST00000159565.1
4931429L15Rik
RIKEN cDNA 4931429L15 gene
chrX_+_169685191 0.448 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr4_+_62525369 0.444 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr17_-_49564262 0.444 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr9_+_123478693 0.441 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr7_-_44669308 0.440 ENSMUST00000148487.1
Myh14
myosin, heavy polypeptide 14
chr6_-_124738579 0.437 ENSMUST00000174265.1
ENSMUST00000004377.8
Ptpn6

protein tyrosine phosphatase, non-receptor type 6

chr5_-_143113008 0.437 ENSMUST00000053498.8
Rnf216
ring finger protein 216
chr4_+_53440388 0.436 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr8_-_11008458 0.433 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr3_+_51483966 0.433 ENSMUST00000054387.6
Rab33b
RAB33B, member of RAS oncogene family
chr1_+_169655493 0.432 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr13_-_81633119 0.423 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr11_+_84957775 0.421 ENSMUST00000103194.3
Car4
carbonic anhydrase 4
chr14_+_75845093 0.420 ENSMUST00000110894.2
Tpt1
tumor protein, translationally-controlled 1
chr13_+_56609516 0.420 ENSMUST00000045173.8
Tgfbi
transforming growth factor, beta induced
chr13_-_12461432 0.420 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
Lgals8



lectin, galactose binding, soluble 8



chr3_+_96833218 0.410 ENSMUST00000128789.1
Pdzk1
PDZ domain containing 1
chr7_-_44816586 0.406 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr2_-_150255591 0.406 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr11_+_4620067 0.404 ENSMUST00000109941.1
Gm11032
predicted gene 11032
chr11_+_32205483 0.403 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr4_-_11965699 0.399 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr2_+_102659213 0.397 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_+_20696175 0.397 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr10_+_21978643 0.395 ENSMUST00000142174.1
ENSMUST00000164659.1
Sgk1

serum/glucocorticoid regulated kinase 1

chr7_-_44496406 0.393 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
Emc10



ER membrane protein complex subunit 10



chr3_+_76075583 0.391 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr16_-_77602094 0.391 ENSMUST00000114231.1
Gm11146
predicted gene 11146
chr7_+_128237357 0.390 ENSMUST00000044660.5
Armc5
armadillo repeat containing 5
chr8_-_13890233 0.389 ENSMUST00000033839.7
Coprs
coordinator of PRMT5, differentiation stimulator
chr3_+_121291725 0.388 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr5_+_144255223 0.387 ENSMUST00000056578.6
Bri3
brain protein I3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0030421 defecation(GO:0030421)
0.8 3.9 GO:0002339 B cell selection(GO:0002339)
0.6 1.8 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) atrial septum primum morphogenesis(GO:0003289) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.6 2.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.5 2.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 1.6 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.5 2.9 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.4 1.7 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.4 1.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 0.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 1.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 1.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 1.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 2.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.3 0.8 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 1.1 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.3 1.5 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 0.9 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 1.2 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.2 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 0.7 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 0.6 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 0.6 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.2 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.6 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.2 0.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.2 3.3 GO:0035994 response to muscle stretch(GO:0035994)
0.2 0.5 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.2 0.7 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 1.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 0.7 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.2 0.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 0.5 GO:2000851 corticosterone secretion(GO:0035934) positive regulation of glucocorticoid secretion(GO:2000851) regulation of corticosterone secretion(GO:2000852)
0.2 0.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 0.5 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 0.9 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.2 0.8 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.6 GO:0061010 gall bladder development(GO:0061010)
0.1 0.8 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.6 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.4 GO:1900673 olefin metabolic process(GO:1900673)
0.1 0.4 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.4 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.6 GO:0015871 choline transport(GO:0015871)
0.1 0.4 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.1 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.3 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.5 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.8 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 1.2 GO:0042428 serotonin metabolic process(GO:0042428)
0.1 1.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.9 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.1 0.4 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.6 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.2 GO:0002385 mucosal immune response(GO:0002385)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 1.4 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 3.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.0 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:2000256 positive regulation of male germ cell proliferation(GO:2000256)
0.1 0.4 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.3 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.3 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.8 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 0.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793)
0.1 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.9 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.7 GO:0006833 water transport(GO:0006833)
0.1 1.5 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 0.4 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.5 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.6 GO:0040031 snRNA modification(GO:0040031)
0.1 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.3 GO:0071638 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.7 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.4 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 0.4 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.2 GO:0032497 detection of molecule of bacterial origin(GO:0032490) detection of lipopolysaccharide(GO:0032497)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 2.5 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.2 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.2 GO:0010958 regulation of amino acid import(GO:0010958)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:0015744 succinate transport(GO:0015744)
0.1 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.3 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.3 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0070309 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) lens fiber cell morphogenesis(GO:0070309) negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.2 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.0 0.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 1.5 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of JNK cascade(GO:0046329) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.2 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:1903960 negative regulation of anion transmembrane transport(GO:1903960)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.4 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0010829 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0007602 phototransduction(GO:0007602)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.0 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 3.3 GO:0035976 AP1 complex(GO:0035976)
0.5 1.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.5 2.0 GO:0019815 B cell receptor complex(GO:0019815)
0.3 0.9 GO:0044299 C-fiber(GO:0044299)
0.3 0.8 GO:0005584 collagen type I trimer(GO:0005584)
0.3 1.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 2.5 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.2 2.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.6 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.2 0.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.4 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 3.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.9 GO:0016528 sarcoplasm(GO:0016528)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0097386 glial cell projection(GO:0097386)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 2.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 4.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.7 2.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.6 2.3 GO:0031720 haptoglobin binding(GO:0031720)
0.5 1.6 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.4 1.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 2.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 1.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.3 5.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 0.8 GO:0005118 sevenless binding(GO:0005118)
0.2 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.2 0.7 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.2 1.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.9 GO:0019770 IgG receptor activity(GO:0019770)
0.2 2.0 GO:0008430 selenium binding(GO:0008430)
0.2 2.2 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.6 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.6 GO:0042806 fucose binding(GO:0042806)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.4 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.1 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 0.4 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 0.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 5.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.9 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) dehydroascorbic acid transporter activity(GO:0033300) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.8 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 2.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 1.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.0 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.8 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0048038 quinone binding(GO:0048038)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 1.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.2 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 4.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.9 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.5 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.0 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 1.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.2 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 3.3 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.1 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.9 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.1 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.9 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.5 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.4 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 2.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.2 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds