Motif ID: Tbx15

Z-value: 0.728


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_125490688 12.236 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr4_+_48045144 4.251 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr3_-_82074639 4.180 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr16_-_23988852 3.788 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr6_+_108213086 3.686 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr10_+_123264076 3.433 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr8_+_23035116 3.306 ENSMUST00000117296.1
ENSMUST00000141784.2
Ank1

ankyrin 1, erythroid

chr11_+_98348404 3.176 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr5_+_32136458 2.939 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chr2_-_57114970 2.849 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr17_-_81649607 2.693 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr19_-_10304867 2.671 ENSMUST00000039327.4
Dagla
diacylglycerol lipase, alpha
chr18_-_74961252 2.538 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr1_+_153665274 2.437 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr9_+_47530173 2.353 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr1_+_153665666 2.336 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr6_-_28831747 2.271 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr7_+_79810727 2.252 ENSMUST00000107394.1
Mesp2
mesoderm posterior 2
chr15_-_12592556 2.135 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr17_+_48932368 2.111 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr4_-_129121889 2.070 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr4_+_13751297 2.057 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_41401304 2.013 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr15_-_11905609 1.959 ENSMUST00000066529.3
Npr3
natriuretic peptide receptor 3
chrX_+_41401128 1.930 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr2_-_64975762 1.916 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr13_-_43304153 1.891 ENSMUST00000055341.5
Gfod1
glucose-fructose oxidoreductase domain containing 1
chr17_-_29237759 1.846 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr1_+_152399824 1.835 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr15_-_71727815 1.775 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr19_-_37207293 1.694 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr2_+_140395309 1.669 ENSMUST00000110067.1
ENSMUST00000110064.1
ENSMUST00000110063.1
ENSMUST00000110062.1
ENSMUST00000078027.5
ENSMUST00000043836.7
Macrod2





MACRO domain containing 2





chr14_-_55116935 1.661 ENSMUST00000022819.5
Jph4
junctophilin 4
chr9_-_4796218 1.650 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
Gria4


glutamate receptor, ionotropic, AMPA4 (alpha 4)


chr2_-_45117349 1.638 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_59568068 1.615 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr9_-_49798729 1.600 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr7_-_98162318 1.569 ENSMUST00000107112.1
Capn5
calpain 5
chrX_+_153359613 1.555 ENSMUST00000039545.4
Klf8
Kruppel-like factor 8
chr9_-_49798905 1.548 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr3_+_96181151 1.527 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr3_-_145649970 1.492 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr3_-_121263159 1.487 ENSMUST00000128909.1
Tmem56
transmembrane protein 56
chr11_+_98741871 1.481 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr12_-_78980758 1.471 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr8_+_84148025 1.468 ENSMUST00000143833.1
ENSMUST00000118856.1
4930432K21Rik

RIKEN cDNA 4930432K21 gene

chr16_+_72663143 1.463 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chrX_+_159840463 1.451 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr5_+_107331157 1.448 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr19_-_46327121 1.440 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr2_-_13011747 1.439 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr3_-_121263314 1.432 ENSMUST00000029777.7
Tmem56
transmembrane protein 56
chr11_+_83662579 1.430 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chr14_-_30353468 1.429 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr3_+_55461758 1.413 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr4_-_150652097 1.378 ENSMUST00000117997.1
ENSMUST00000037827.3
Slc45a1

solute carrier family 45, member 1

chr8_+_84148252 1.364 ENSMUST00000093375.4
4930432K21Rik
RIKEN cDNA 4930432K21 gene
chr11_+_98741805 1.363 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr14_+_27238018 1.334 ENSMUST00000049206.5
Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr13_-_117025505 1.317 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr7_-_78577771 1.310 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chrX_-_157492280 1.293 ENSMUST00000112529.1
Sms
spermine synthase
chr15_-_101850778 1.276 ENSMUST00000023790.3
Krt1
keratin 1
chr6_-_82939676 1.211 ENSMUST00000000641.9
ENSMUST00000113982.1
Sema4f

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

chr4_+_117849361 1.206 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr6_+_114131229 1.202 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr2_+_32609043 1.198 ENSMUST00000128811.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr5_+_143622466 1.180 ENSMUST00000177196.1
Cyth3
cytohesin 3
chr1_+_153665627 1.164 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr17_-_37023349 1.163 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr9_-_20879718 1.162 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr5_+_143622440 1.162 ENSMUST00000116456.3
Cyth3
cytohesin 3
chr14_+_45351473 1.159 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chr10_-_13868932 1.132 ENSMUST00000019942.5
ENSMUST00000162610.1
Aig1

androgen-induced 1

chr1_+_153665587 1.124 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr2_+_140395446 1.121 ENSMUST00000110061.1
Macrod2
MACRO domain containing 2
chrX_+_152016428 1.119 ENSMUST00000045312.5
Smc1a
structural maintenance of chromosomes 1A
chr7_-_114117761 1.090 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr5_-_8367982 1.078 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr16_-_43979050 1.077 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr10_+_56377300 1.068 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chrX_+_7919816 1.061 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr6_-_24956106 1.054 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chrX_-_52165252 1.049 ENSMUST00000033450.2
Gpc4
glypican 4
chr8_-_125898291 1.022 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr6_+_50110186 1.017 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
Mpp6


membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)


chr5_-_84417359 1.005 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr6_+_50110837 1.001 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr13_+_29014399 0.986 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr12_+_105336922 0.979 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr4_-_82505749 0.975 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr14_+_4110526 0.970 ENSMUST00000170207.1
Gm8108
predicted gene 8108
chr1_-_40790642 0.957 ENSMUST00000039672.5
Mfsd9
major facilitator superfamily domain containing 9
chr19_-_45591820 0.957 ENSMUST00000160003.1
ENSMUST00000162879.1
Fbxw4

F-box and WD-40 domain protein 4

chr8_-_84147858 0.951 ENSMUST00000117424.2
ENSMUST00000040383.8
Cc2d1a

coiled-coil and C2 domain containing 1A

chr2_-_132145057 0.932 ENSMUST00000028815.8
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr4_+_148000722 0.922 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr18_+_36559972 0.914 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr8_+_84723003 0.907 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr6_-_131313827 0.906 ENSMUST00000049150.1
Styk1
serine/threonine/tyrosine kinase 1
chr7_-_113369326 0.898 ENSMUST00000047091.7
ENSMUST00000119278.1
Btbd10

BTB (POZ) domain containing 10

chr18_-_36726730 0.893 ENSMUST00000061829.6
Cd14
CD14 antigen
chr11_-_22286795 0.888 ENSMUST00000109563.2
ENSMUST00000180360.1
Ehbp1

EH domain binding protein 1

chr1_+_133309778 0.888 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr12_-_31634592 0.886 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr11_+_121237216 0.881 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr7_-_78578308 0.875 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr13_+_109685994 0.874 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr11_+_78032274 0.868 ENSMUST00000021187.5
Dhrs13
dehydrogenase/reductase (SDR family) member 13
chr4_-_129440800 0.862 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr4_-_126753372 0.856 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr11_+_84179792 0.837 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chr4_+_84884418 0.835 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr3_-_94582548 0.833 ENSMUST00000107283.1
Snx27
sorting nexin family member 27
chr3_+_40950631 0.827 ENSMUST00000048490.6
Larp1b
La ribonucleoprotein domain family, member 1B
chr19_-_45660312 0.818 ENSMUST00000046869.4
Fbxw4
F-box and WD-40 domain protein 4
chr3_-_94582716 0.815 ENSMUST00000029783.9
Snx27
sorting nexin family member 27
chr1_+_60409612 0.803 ENSMUST00000052332.8
Abi2
abl-interactor 2
chr5_-_148399901 0.800 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_+_25242929 0.799 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr11_+_83302641 0.796 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr11_+_23306910 0.794 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr5_-_148371525 0.773 ENSMUST00000138596.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr7_-_126897424 0.769 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chrX_+_136666375 0.757 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
Tceal3


transcription elongation factor A (SII)-like 3


chr3_+_75557530 0.755 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr12_+_33314277 0.752 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr3_-_89773221 0.748 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr11_-_86544754 0.744 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
Rps6kb1


ribosomal protein S6 kinase, polypeptide 1


chr13_+_56609516 0.737 ENSMUST00000045173.8
Tgfbi
transforming growth factor, beta induced
chr10_-_25200110 0.727 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr18_+_37473538 0.720 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr4_+_84884276 0.717 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr8_-_121907678 0.717 ENSMUST00000045557.9
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr11_-_80779989 0.714 ENSMUST00000041065.7
ENSMUST00000070997.5
Myo1d

myosin ID

chr9_+_27299205 0.694 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr10_-_81472859 0.693 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chrX_-_59567348 0.687 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr3_+_33799791 0.687 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr4_+_114680769 0.682 ENSMUST00000146346.1
Gm12829
predicted gene 12829
chr11_+_95414078 0.680 ENSMUST00000107724.2
ENSMUST00000150884.1
ENSMUST00000107722.1
ENSMUST00000127713.1
Spop



speckle-type POZ protein



chr4_-_55532453 0.675 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr4_+_117849193 0.654 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr4_+_108328136 0.649 ENSMUST00000131656.1
Selrc1
Sel1 repeat containing 1
chr11_-_116654245 0.648 ENSMUST00000021166.5
Cygb
cytoglobin
chr7_+_126928844 0.647 ENSMUST00000032924.5
Kctd13
potassium channel tetramerisation domain containing 13
chr11_+_78032346 0.644 ENSMUST00000122342.1
ENSMUST00000092881.3
Dhrs13

dehydrogenase/reductase (SDR family) member 13

chr13_+_54503779 0.642 ENSMUST00000121401.1
ENSMUST00000118072.1
ENSMUST00000159721.1
Simc1


SUMO-interacting motifs containing 1


chr16_-_9994921 0.641 ENSMUST00000115835.1
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr16_+_23107413 0.640 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chrX_-_101419788 0.625 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr12_-_35534973 0.614 ENSMUST00000116436.2
Ahr
aryl-hydrocarbon receptor
chr2_+_136891501 0.612 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr13_-_32338565 0.601 ENSMUST00000041859.7
Gmds
GDP-mannose 4, 6-dehydratase
chr10_-_127263346 0.598 ENSMUST00000099172.3
Kif5a
kinesin family member 5A
chr4_-_151108244 0.588 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr8_+_106935720 0.587 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr3_-_107969162 0.577 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr5_+_136919137 0.577 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr11_+_83302817 0.576 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chrX_+_100730178 0.574 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr13_+_81657732 0.573 ENSMUST00000049055.6
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr16_+_55973881 0.572 ENSMUST00000050248.8
Rpl24
ribosomal protein L24
chr5_-_134176720 0.568 ENSMUST00000076228.2
Wbscr16
Williams-Beuren syndrome chromosome region 16 homolog (human)
chr11_-_83302586 0.566 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chrX_-_101420206 0.563 ENSMUST00000118092.1
Zmym3
zinc finger, MYM-type 3
chr15_-_82912134 0.563 ENSMUST00000048966.5
ENSMUST00000109510.2
Tcf20

transcription factor 20

chr5_-_137684665 0.560 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr4_+_53440516 0.545 ENSMUST00000107651.2
ENSMUST00000107647.1
Slc44a1

solute carrier family 44, member 1

chr9_-_122862128 0.543 ENSMUST00000056467.7
Zfp445
zinc finger protein 445
chr8_-_40634750 0.542 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr4_-_129121699 0.540 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chrM_+_10167 0.538 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr17_-_6449571 0.530 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr2_+_25242227 0.526 ENSMUST00000154498.1
Rnf208
ring finger protein 208
chrX_-_101420348 0.524 ENSMUST00000119699.1
Zmym3
zinc finger, MYM-type 3
chr17_-_6621267 0.523 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr2_-_91183017 0.522 ENSMUST00000066420.5
Madd
MAP-kinase activating death domain
chr11_+_23306884 0.516 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr7_+_18987518 0.515 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr2_-_127143306 0.514 ENSMUST00000110386.1
Itpripl1
inositol 1,4,5-triphosphate receptor interacting protein-like 1
chr16_+_84835070 0.513 ENSMUST00000009120.7
Gabpa
GA repeat binding protein, alpha
chr7_+_30169861 0.509 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr17_-_35895920 0.505 ENSMUST00000059740.8
2310061I04Rik
RIKEN cDNA 2310061I04 gene
chr10_-_86705485 0.499 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr14_-_68655804 0.498 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr1_+_180726019 0.498 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr11_+_70018728 0.497 ENSMUST00000018700.6
ENSMUST00000134376.2
Dlg4

discs, large homolog 4 (Drosophila)

chr2_+_125136692 0.495 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr18_+_38296805 0.493 ENSMUST00000171461.1
Rnf14
ring finger protein 14
chr7_-_24316590 0.483 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr7_-_30169701 0.480 ENSMUST00000062181.7
Zfp146
zinc finger protein 146
chr16_-_18413452 0.478 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt

catechol-O-methyltransferase

chr2_-_91182848 0.473 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
Madd


MAP-kinase activating death domain


chr15_-_79164477 0.472 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr19_+_8617991 0.472 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr8_-_40634776 0.451 ENSMUST00000048898.10
ENSMUST00000174205.1
Mtmr7

myotubularin related protein 7

chr11_+_98937669 0.449 ENSMUST00000107475.2
ENSMUST00000068133.3
Rara

retinoic acid receptor, alpha

chr5_-_24601961 0.448 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr18_+_38296635 0.441 ENSMUST00000072376.5
ENSMUST00000170811.1
Rnf14

ring finger protein 14


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.0 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
1.4 4.2 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
1.3 2.7 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
1.1 12.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.1 3.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.0 3.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.9 2.8 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.9 2.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.9 2.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.8 2.4 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.7 2.2 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 2.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.7 2.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.6 1.9 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.6 2.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.6 1.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 3.7 GO:0042045 epithelial fluid transport(GO:0042045)
0.6 1.7 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 2.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.5 7.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159)
0.5 1.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 1.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.4 1.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 2.0 GO:0002158 osteoclast proliferation(GO:0002158)
0.4 1.9 GO:0060591 chondroblast differentiation(GO:0060591)
0.4 1.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.4 2.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 1.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 1.1 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.3 1.0 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.3 0.9 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 1.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 1.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 0.7 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2 0.9 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 0.9 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.2 0.8 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.2 1.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.2 0.7 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 0.5 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.2 0.5 GO:0015747 urate transport(GO:0015747)
0.2 2.9 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.6 GO:0040010 positive regulation of growth rate(GO:0040010)
0.2 1.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 3.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.5 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.6 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 1.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.6 GO:0015871 choline transport(GO:0015871)
0.1 0.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 1.4 GO:0007141 male meiosis I(GO:0007141)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 1.6 GO:0015809 arginine transport(GO:0015809)
0.1 1.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.8 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 1.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.9 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.6 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.4 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.1 3.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 3.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 1.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 1.7 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 0.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.3 GO:0015867 ATP transport(GO:0015867)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.4 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.9 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0019043 establishment of viral latency(GO:0019043)
0.0 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.1 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.9 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.2 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 1.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.6 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0003283 atrial septum development(GO:0003283)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 2.1 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.0 0.2 GO:0097502 mannosylation(GO:0097502)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.4 GO:0015844 monoamine transport(GO:0015844)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.4 16.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 1.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.3 1.7 GO:0030314 junctional membrane complex(GO:0030314)
0.3 5.0 GO:0043196 varicosity(GO:0043196)
0.3 0.3 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.3 1.1 GO:0030673 axolemma(GO:0030673)
0.3 3.9 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.2 GO:0001533 cornified envelope(GO:0001533)
0.2 0.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 1.6 GO:0071203 WASH complex(GO:0071203)
0.2 1.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 4.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 7.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 0.8 GO:0031983 vesicle lumen(GO:0031983)
0.2 3.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.9 GO:0042629 mast cell granule(GO:0042629)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 3.9 GO:0014704 intercalated disc(GO:0014704)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.6 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.7 GO:0005657 replication fork(GO:0005657)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 6.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 2.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.2 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0098793 presynapse(GO:0098793)
0.0 0.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 12.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.2 3.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.1 3.2 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.9 2.8 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.8 5.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 2.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.6 2.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 2.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 1.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 1.5 GO:0036033 mediator complex binding(GO:0036033)
0.3 4.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 1.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 3.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 0.9 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 0.9 GO:0071723 lipopeptide binding(GO:0071723)
0.3 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 1.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 4.6 GO:0030275 LRR domain binding(GO:0030275)
0.2 1.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 7.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 7.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.6 GO:0004096 catalase activity(GO:0004096)
0.2 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 3.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 2.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.3 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 1.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.8 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.3 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.0 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 1.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 2.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.6 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.7 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 2.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 4.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.1 PID_ATM_PATHWAY ATM pathway
0.1 3.6 PID_FOXO_PATHWAY FoxO family signaling
0.0 3.1 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.9 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.4 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.9 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.9 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 1.5 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.4 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 3.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.6 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.0 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 3.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 7.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 2.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 10.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 3.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.7 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.5 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.5 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 2.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.1 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 0.5 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 7.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 1.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.2 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.9 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage