Motif ID: Tbx3

Z-value: 0.211


Transcription factors associated with Tbx3:

Gene SymbolEntrez IDGene Name
Tbx3 ENSMUSG00000018604.12 Tbx3



Activity profile for motif Tbx3.

activity profile for motif Tbx3


Sorted Z-values histogram for motif Tbx3

Sorted Z-values for motif Tbx3



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_100970887 0.548 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr10_-_18743691 0.388 ENSMUST00000019999.5
 D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr10_+_56377300 0.328 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr17_-_59013264 0.328 ENSMUST00000174122.1
ENSMUST00000025065.5
 Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr18_-_23981555 0.318 ENSMUST00000115829.1
 Zscan30
zinc finger and SCAN domain containing 30
chr5_-_106926245 0.274 ENSMUST00000117588.1
 Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr1_-_31222604 0.272 ENSMUST00000127775.1
 4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr2_+_154551771 0.267 ENSMUST00000104928.1
 Actl10
actin-like 10
chr12_-_84361802 0.241 ENSMUST00000021659.1
ENSMUST00000065536.2
 Fam161b

family with sequence similarity 161, member B

chrX_-_20931520 0.201 ENSMUST00000001156.7
 Cfp
complement factor properdin
chr7_+_112374839 0.141 ENSMUST00000106645.1
 Micalcl
MICAL C-terminal like
chr19_+_7494033 0.133 ENSMUST00000170373.1
 Atl3
atlastin GTPase 3
chr14_+_67745229 0.113 ENSMUST00000111095.2
 Gnrh1
gonadotropin releasing hormone 1
chr7_-_4522427 0.103 ENSMUST00000098859.3
 Tnni3
troponin I, cardiac 3
chr7_-_4522794 0.080 ENSMUST00000140424.1
 Tnni3
troponin I, cardiac 3
chr7_+_107567445 0.056 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr11_-_94507337 0.044 ENSMUST00000040692.8
 Mycbpap
MYCBP associated protein
chr10_+_127514939 0.041 ENSMUST00000035735.9
 Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr12_+_84361968 0.039 ENSMUST00000021661.6
 Coq6
coenzyme Q6 homolog (yeast)
chr12_+_84361636 0.026 ENSMUST00000110276.1
 Coq6
coenzyme Q6 homolog (yeast)
chr12_+_84362029 0.025 ENSMUST00000110278.1
ENSMUST00000145522.1
 Coq6

coenzyme Q6 homolog (yeast)

chr19_+_7056731 0.007 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.1 0.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0030172 troponin C binding(GO:0030172)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination