Motif ID: Tfcp2l1

Z-value: 0.699


Transcription factors associated with Tfcp2l1:

Gene SymbolEntrez IDGene Name
Tfcp2l1 ENSMUSG00000026380.9 Tfcp2l1



Activity profile for motif Tfcp2l1.

activity profile for motif Tfcp2l1


Sorted Z-values histogram for motif Tfcp2l1

Sorted Z-values for motif Tfcp2l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2l1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_172549581 6.493 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr16_-_22161450 3.882 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr15_-_98004695 3.464 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr15_-_98004634 3.356 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr5_+_114568016 2.045 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr5_+_30105161 2.026 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr3_-_101836223 1.998 ENSMUST00000061831.4
Mab21l3
mab-21-like 3 (C. elegans)
chr16_-_76403673 1.978 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr17_+_35059035 1.587 ENSMUST00000007255.6
ENSMUST00000174493.1
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr8_+_57511833 1.560 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr1_+_184034381 1.494 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr2_-_91931696 1.464 ENSMUST00000090602.5
Mdk
midkine
chr4_-_133967953 1.360 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr4_-_133967893 1.342 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr2_-_91931774 1.313 ENSMUST00000069423.6
Mdk
midkine
chr9_+_45138437 1.287 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr14_-_31251194 1.247 ENSMUST00000022459.3
Phf7
PHD finger protein 7
chr14_+_11553523 1.213 ENSMUST00000022264.6
Ptprg
protein tyrosine phosphatase, receptor type, G
chr19_+_48206025 1.123 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr14_+_31251454 1.094 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chr2_+_157424255 1.026 ENSMUST00000029175.7
ENSMUST00000092576.4
Src

Rous sarcoma oncogene

chr12_+_17544873 0.962 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr7_-_38107490 0.944 ENSMUST00000108023.3
Ccne1
cyclin E1
chr3_+_89773562 0.865 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr4_-_135573623 0.854 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr1_+_5083105 0.815 ENSMUST00000044369.7
Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
chr3_+_95164306 0.764 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chrX_-_7319186 0.733 ENSMUST00000115746.1
Clcn5
chloride channel 5
chr4_+_118428078 0.711 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chr6_-_90810118 0.700 ENSMUST00000101151.3
Iqsec1
IQ motif and Sec7 domain 1
chr9_+_107888129 0.700 ENSMUST00000035202.2
Mon1a
MON1 homolog A (yeast)
chr7_-_25390098 0.691 ENSMUST00000054301.7
Lipe
lipase, hormone sensitive
chr5_-_138263942 0.641 ENSMUST00000048421.7
ENSMUST00000164203.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr5_-_138264013 0.623 ENSMUST00000161604.1
ENSMUST00000163268.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr2_+_181187247 0.619 ENSMUST00000016488.6
ENSMUST00000108841.1
Ppdpf

pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)RIKEN cDNA 2700038C09 gene

chr11_-_22982090 0.587 ENSMUST00000093270.5
ENSMUST00000071068.8
ENSMUST00000159081.1
ENSMUST00000160826.1
Commd1


RP23-242C19.7
COMM domain containing 1


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3gnt2), transcript variant 2, mRNA
chr8_-_124434323 0.554 ENSMUST00000140012.1
Pgbd5
piggyBac transposable element derived 5
chr2_+_154551771 0.540 ENSMUST00000104928.1
Actl10
actin-like 10
chr11_-_69822144 0.522 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr7_-_99238564 0.511 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr7_-_97332017 0.506 ENSMUST00000139582.2
Usp35
ubiquitin specific peptidase 35
chrX_-_7319291 0.489 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr11_-_3452355 0.468 ENSMUST00000064364.2
ENSMUST00000077078.5
Rnf185

ring finger protein 185

chr5_-_30907692 0.451 ENSMUST00000132034.2
ENSMUST00000132253.2
Ost4

oligosaccharyltransferase 4 homolog (S. cerevisiae)

chr10_-_128589650 0.446 ENSMUST00000082059.6
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr2_+_128126030 0.445 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr5_-_31202215 0.415 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr9_-_108649349 0.413 ENSMUST00000013338.8
Arih2
ariadne homolog 2 (Drosophila)
chr11_+_75532099 0.400 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr1_-_184033998 0.400 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr4_-_117887292 0.395 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr2_-_38714491 0.395 ENSMUST00000028084.4
Nr5a1
nuclear receptor subfamily 5, group A, member 1
chr16_+_20717665 0.390 ENSMUST00000021405.7
Polr2h
polymerase (RNA) II (DNA directed) polypeptide H
chr15_+_80234071 0.379 ENSMUST00000023048.4
ENSMUST00000166030.1
Mief1

mitochondrial elongation factor 1

chr5_+_30647921 0.379 ENSMUST00000062962.5
Slc35f6
solute carrier family 35, member F6
chr2_+_11339461 0.378 ENSMUST00000131188.1
Gm13293
predicted gene 13293
chr8_-_79399513 0.371 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
Smad1


SMAD family member 1


chr9_+_108936648 0.366 ENSMUST00000026743.8
Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
chr7_+_97332311 0.349 ENSMUST00000054107.5
Kctd21
potassium channel tetramerisation domain containing 21
chr4_-_124850473 0.349 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr6_+_91157373 0.347 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr7_-_103741322 0.345 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr7_+_82867327 0.330 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chrX_-_140543177 0.329 ENSMUST00000055738.5
Tsc22d3
TSC22 domain family, member 3
chr15_-_77970750 0.321 ENSMUST00000100484.4
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr11_-_105937798 0.321 ENSMUST00000183493.1
Cyb561
cytochrome b-561
chr4_-_117887279 0.313 ENSMUST00000132073.1
Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
chr1_+_171329376 0.312 ENSMUST00000111299.1
ENSMUST00000064950.4
Dedd

death effector domain-containing

chr17_-_45685973 0.308 ENSMUST00000145873.1
Tmem63b
transmembrane protein 63b
chr2_+_156721009 0.298 ENSMUST00000131157.2
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr4_-_134012381 0.289 ENSMUST00000176113.1
Lin28a
lin-28 homolog A (C. elegans)
chr6_-_84593810 0.287 ENSMUST00000077705.3
ENSMUST00000168003.2
Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chr3_+_103575275 0.287 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr2_-_26122769 0.283 ENSMUST00000140993.1
ENSMUST00000028300.5
Nacc2

nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

chr17_-_45686120 0.279 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr11_+_75531690 0.267 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chrX_+_151046131 0.265 ENSMUST00000112685.1
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr1_+_74236479 0.259 ENSMUST00000113820.2
ENSMUST00000006467.7
ENSMUST00000113819.1
Arpc2


actin related protein 2/3 complex, subunit 2


chr11_+_101325063 0.254 ENSMUST00000041095.7
ENSMUST00000107264.1
Aoc2

amine oxidase, copper containing 2 (retina-specific)

chr18_-_9450097 0.247 ENSMUST00000053917.4
Ccny
cyclin Y
chrX_+_151047170 0.239 ENSMUST00000026296.7
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr7_+_130692532 0.238 ENSMUST00000033141.6
Tacc2
transforming, acidic coiled-coil containing protein 2
chr1_-_132707304 0.225 ENSMUST00000043189.7
Nfasc
neurofascin
chr11_+_77982710 0.222 ENSMUST00000108360.1
ENSMUST00000049167.7
Phf12

PHD finger protein 12

chr6_-_112946754 0.208 ENSMUST00000113169.2
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr4_-_133339283 0.203 ENSMUST00000043305.7
Wdtc1
WD and tetratricopeptide repeats 1
chr4_-_53262547 0.203 ENSMUST00000098075.2
AI427809
expressed sequence AI427809
chr12_-_4907229 0.198 ENSMUST00000142867.1
Ubxn2a
UBX domain protein 2A
chr3_+_103575231 0.183 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr4_-_147936713 0.171 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr4_-_133339238 0.160 ENSMUST00000105906.1
Wdtc1
WD and tetratricopeptide repeats 1
chr2_+_91265252 0.160 ENSMUST00000028691.6
Arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr11_+_99864476 0.157 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr3_-_62605140 0.155 ENSMUST00000058535.5
Gpr149
G protein-coupled receptor 149
chrX_+_52791179 0.151 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr11_+_75532127 0.135 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr4_+_125085134 0.088 ENSMUST00000154689.1
ENSMUST00000055213.4
ENSMUST00000106171.2
Meaf6


MYST/Esa1-associated factor 6


chr2_+_156721037 0.084 ENSMUST00000109566.2
ENSMUST00000146412.2
ENSMUST00000177013.1
ENSMUST00000171030.2
Dlgap4



discs, large homolog-associated protein 4 (Drosophila)



chr9_+_108648720 0.083 ENSMUST00000098384.2
Gm10621
predicted gene 10621
chr16_-_18235074 0.075 ENSMUST00000076957.5
Zdhhc8
zinc finger, DHHC domain containing 8
chr9_+_96119362 0.065 ENSMUST00000085217.5
ENSMUST00000122383.1
Gk5

glycerol kinase 5 (putative)

chr1_+_171018920 0.065 ENSMUST00000078825.4
Fcgr4
Fc receptor, IgG, low affinity IV
chr2_+_156721069 0.056 ENSMUST00000000094.7
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr12_-_4907705 0.049 ENSMUST00000020962.5
Ubxn2a
UBX domain protein 2A
chr12_+_14494561 0.041 ENSMUST00000052528.3
Gm9847
predicted pseudogene 9847
chr19_-_8929323 0.033 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr12_-_100520778 0.008 ENSMUST00000062957.6
Ttc7b
tetratricopeptide repeat domain 7B
chr2_-_178414460 0.002 ENSMUST00000058678.4
Ppp1r3d
protein phosphatase 1, regulatory subunit 3D

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.9 2.8 GO:0030421 defecation(GO:0030421)
0.6 6.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 1.0 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.3 1.5 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 1.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 1.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.2 0.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 0.6 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2 0.9 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.2 0.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 1.6 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.4 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 2.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.4 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.1 0.3 GO:0098528 terpenoid catabolic process(GO:0016115) skeletal muscle fiber differentiation(GO:0098528)
0.1 0.3 GO:2000812 response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 1.3 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.1 0.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.5 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.6 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 1.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 3.9 GO:0051028 mRNA transport(GO:0051028)
0.0 0.9 GO:0007129 synapsis(GO:0007129)
0.0 1.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 1.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 3.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.0 GO:0071253 connexin binding(GO:0071253)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 5.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 2.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 NABA_COLLAGENS Genes encoding collagen proteins
0.1 6.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 2.0 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.0 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 3.4 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.0 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.6 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP