Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
Z-value: 1.114
Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bhlhe41 | ENSMUSG00000030256.5 | Bhlhe41 |
| Srebf1 | ENSMUSG00000020538.9 | Srebf1 |
| Srebf2 | ENSMUSG00000022463.7 | Srebf2 |
| Tfeb | ENSMUSG00000023990.12 | Tfeb |
| Usf1 | ENSMUSG00000026641.7 | Usf1 |
| Usf2 | ENSMUSG00000058239.7 | Usf2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Srebf2 | mm10_v2_chr15_+_82147238_82147275 | -0.41 | 7.9e-03 | Click! |
| Usf2 | mm10_v2_chr7_-_30956742_30956803 | -0.37 | 1.9e-02 | Click! |
| Srebf1 | mm10_v2_chr11_-_60210410_60210465 | 0.30 | 5.6e-02 | Click! |
| Usf1 | mm10_v2_chr1_+_171411305_171411337 | -0.23 | 1.5e-01 | Click! |
| Tfeb | mm10_v2_chr17_+_47785720_47785739 | 0.10 | 5.2e-01 | Click! |
First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
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Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 13.8 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 2.8 | 8.5 | GO:1904959 | elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
| 2.8 | 8.5 | GO:1904170 | regulation of bleb assembly(GO:1904170) |
| 2.8 | 11.1 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 2.6 | 7.7 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
| 2.1 | 8.4 | GO:0010288 | response to lead ion(GO:0010288) |
| 1.6 | 4.9 | GO:0030421 | defecation(GO:0030421) |
| 1.6 | 6.4 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 1.6 | 4.7 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 1.4 | 7.0 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 1.4 | 5.6 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) |
| 1.4 | 9.6 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 1.4 | 4.1 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
| 1.3 | 4.0 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 1.3 | 6.4 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
| 1.2 | 5.0 | GO:0002188 | translation reinitiation(GO:0002188) |
| 1.2 | 6.0 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 1.1 | 6.8 | GO:1903564 | regulation of protein localization to cilium(GO:1903564) |
| 1.0 | 4.2 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 1.0 | 3.1 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.9 | 4.5 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.9 | 3.6 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.8 | 4.9 | GO:0035630 | bone mineralization involved in bone maturation(GO:0035630) |
| 0.7 | 4.5 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.7 | 7.1 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 0.7 | 2.8 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.7 | 2.0 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
| 0.6 | 3.9 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.6 | 3.2 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.6 | 1.9 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.6 | 1.9 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.6 | 4.4 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.6 | 6.9 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.6 | 2.5 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.6 | 2.4 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.6 | 4.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.6 | 2.4 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.6 | 4.0 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.6 | 5.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.6 | 2.8 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.6 | 1.7 | GO:0070428 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
| 0.6 | 1.7 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.5 | 4.3 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.5 | 1.1 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.5 | 2.1 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.5 | 1.5 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.5 | 1.0 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.5 | 2.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.5 | 5.1 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.4 | 3.6 | GO:0015074 | DNA integration(GO:0015074) |
| 0.4 | 2.7 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.4 | 1.3 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.4 | 2.1 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.4 | 3.3 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.4 | 1.7 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.4 | 3.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.4 | 1.2 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.4 | 9.8 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.4 | 1.2 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
| 0.4 | 3.7 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.4 | 3.6 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.4 | 4.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.4 | 0.4 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.4 | 1.2 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.4 | 1.1 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.4 | 1.5 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.4 | 2.2 | GO:0046502 | uroporphyrinogen III metabolic process(GO:0046502) |
| 0.4 | 2.2 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.4 | 2.6 | GO:0030242 | pexophagy(GO:0030242) |
| 0.4 | 3.7 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.4 | 1.1 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.4 | 2.6 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.4 | 1.5 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 0.4 | 8.0 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.4 | 3.6 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.4 | 3.9 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.3 | 1.0 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.3 | 2.0 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.3 | 1.9 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.3 | 3.5 | GO:0048570 | notochord morphogenesis(GO:0048570) |
| 0.3 | 4.1 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.3 | 1.5 | GO:0072429 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 0.3 | 0.9 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.3 | 1.5 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.3 | 1.8 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.3 | 5.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.3 | 15.1 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.3 | 2.9 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.3 | 5.6 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.3 | 1.9 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.3 | 1.9 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.3 | 1.6 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.3 | 7.4 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.3 | 1.9 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.3 | 1.3 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.3 | 15.9 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.3 | 1.3 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.3 | 0.5 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 1.8 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
| 0.3 | 1.0 | GO:0035826 | rubidium ion transport(GO:0035826) |
| 0.3 | 0.8 | GO:0043622 | cortical microtubule organization(GO:0043622) |
| 0.3 | 1.3 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.3 | 0.8 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566) |
| 0.3 | 3.0 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.2 | 2.2 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.2 | 0.7 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 0.2 | 0.5 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
| 0.2 | 0.7 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
| 0.2 | 0.9 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.2 | 0.9 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.2 | 1.1 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.2 | 1.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.2 | 0.7 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
| 0.2 | 14.7 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.2 | 0.6 | GO:0090649 | rRNA export from nucleus(GO:0006407) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.2 | 0.6 | GO:0021972 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.2 | 3.0 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.2 | 4.8 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.2 | 3.1 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.2 | 1.7 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.2 | 2.4 | GO:0000737 | DNA catabolic process, endonucleolytic(GO:0000737) |
| 0.2 | 2.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.2 | 2.3 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.2 | 1.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.2 | 1.1 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
| 0.2 | 2.4 | GO:0090148 | membrane fission(GO:0090148) |
| 0.2 | 0.4 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.2 | 0.5 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 0.2 | 0.5 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.2 | 2.7 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.2 | 0.7 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 1.7 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.2 | 1.2 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 0.3 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.2 | 0.5 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.2 | 1.8 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 2.1 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.2 | 0.5 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 0.2 | 1.6 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 0.7 | GO:0052151 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) |
| 0.2 | 3.9 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.2 | 0.8 | GO:0035878 | nail development(GO:0035878) |
| 0.2 | 0.5 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 0.2 | 1.4 | GO:0032682 | negative regulation of chemokine production(GO:0032682) |
| 0.2 | 0.3 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.1 | 0.6 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382) |
| 0.1 | 0.4 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.1 | 0.1 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.1 | 0.6 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.1 | 0.9 | GO:0006983 | ER overload response(GO:0006983) |
| 0.1 | 0.8 | GO:1901072 | glucosamine-containing compound catabolic process(GO:1901072) |
| 0.1 | 1.2 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 1.4 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.4 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.1 | 0.5 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.1 | 4.4 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 0.4 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.1 | 1.2 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 1.4 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 0.1 | 0.5 | GO:0003360 | brainstem development(GO:0003360) |
| 0.1 | 2.7 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.1 | 1.8 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.1 | 0.9 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.1 | 0.7 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.1 | 1.6 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.1 | 0.6 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.1 | 0.7 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.1 | 2.6 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 5.8 | GO:0007492 | endoderm development(GO:0007492) |
| 0.1 | 0.7 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 1.0 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.2 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.1 | 0.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 3.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 0.3 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 0.1 | 5.3 | GO:0007628 | adult walking behavior(GO:0007628) |
| 0.1 | 0.4 | GO:0097494 | regulation of vesicle size(GO:0097494) |
| 0.1 | 0.3 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.3 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.1 | 2.1 | GO:2001273 | regulation of glucose import in response to insulin stimulus(GO:2001273) |
| 0.1 | 0.9 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.1 | 0.1 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.1 | 1.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 1.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.2 | GO:0032055 | negative regulation of translation in response to stress(GO:0032055) |
| 0.1 | 2.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 0.8 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.1 | 2.1 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 4.3 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.1 | 1.3 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 3.6 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.1 | 0.6 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 1.2 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.1 | 0.7 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 0.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 3.2 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 0.9 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 0.8 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.1 | 4.2 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
| 0.1 | 0.2 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.1 | 0.4 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.1 | 1.1 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 0.2 | GO:0009218 | UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) pyrimidine ribonucleotide metabolic process(GO:0009218) pyrimidine ribonucleotide biosynthetic process(GO:0009220) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) pyrimidine ribonucleoside biosynthetic process(GO:0046132) |
| 0.1 | 0.4 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 0.9 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 0.2 | GO:0051124 | synaptic growth at neuromuscular junction(GO:0051124) |
| 0.1 | 1.2 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 0.6 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
| 0.1 | 0.8 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.1 | 2.1 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 0.1 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
| 0.1 | 0.4 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
| 0.1 | 0.6 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 1.3 | GO:0014823 | response to activity(GO:0014823) |
| 0.1 | 2.7 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 0.8 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.1 | 0.5 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.1 | 0.2 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.1 | 0.3 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.1 | 0.1 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) |
| 0.1 | 0.4 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.1 | 2.4 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.1 | 0.6 | GO:0006833 | water transport(GO:0006833) |
| 0.1 | 0.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.2 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.1 | 0.1 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.1 | 4.9 | GO:0043473 | pigmentation(GO:0043473) |
| 0.1 | 0.3 | GO:0098734 | protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 3.5 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 0.1 | GO:0003310 | pancreatic A cell differentiation(GO:0003310) |
| 0.1 | 0.7 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.4 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.1 | 2.3 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.1 | 0.4 | GO:0046349 | amino sugar biosynthetic process(GO:0046349) |
| 0.1 | 0.7 | GO:0003338 | metanephros morphogenesis(GO:0003338) |
| 0.1 | 1.1 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 0.3 | GO:1903756 | regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.1 | 0.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.3 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 0.3 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.1 | 1.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 0.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 0.5 | GO:0006544 | glycine metabolic process(GO:0006544) |
| 0.1 | 0.7 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 0.1 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.0 | 0.4 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
| 0.0 | 0.2 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
| 0.0 | 0.6 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.3 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.0 | 0.0 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.0 | 0.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 1.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.5 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.3 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.0 | 3.5 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
| 0.0 | 0.3 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.0 | 0.6 | GO:0045830 | positive regulation of isotype switching(GO:0045830) |
| 0.0 | 0.6 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.0 | 0.4 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.2 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
| 0.0 | 0.4 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.0 | 0.8 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 3.7 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.1 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.0 | 2.0 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.3 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
| 0.0 | 0.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.0 | 1.3 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.0 | 0.2 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.9 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.0 | 0.7 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.0 | 0.7 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
| 0.0 | 0.8 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.3 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.0 | 0.5 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.5 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.0 | 0.2 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.1 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.0 | 0.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.0 | 1.8 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.3 | GO:1903337 | positive regulation of vacuolar transport(GO:1903337) |
| 0.0 | 0.3 | GO:0003222 | ventricular trabecula myocardium morphogenesis(GO:0003222) |
| 0.0 | 0.3 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.1 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.6 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.0 | 0.0 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 0.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.0 | 0.1 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
| 0.0 | 0.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.2 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.0 | 1.0 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.0 | 0.2 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.2 | GO:0045579 | positive regulation of B cell differentiation(GO:0045579) |
| 0.0 | 0.3 | GO:0001779 | natural killer cell differentiation(GO:0001779) |
| 0.0 | 0.4 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.2 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.0 | 0.2 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.1 | GO:0032769 | negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.0 | 2.1 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.1 | GO:0009946 | optic vesicle morphogenesis(GO:0003404) proximal/distal axis specification(GO:0009946) neuroblast migration(GO:0097402) |
| 0.0 | 0.2 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.0 | 1.1 | GO:0060021 | palate development(GO:0060021) |
| 0.0 | 0.1 | GO:0014043 | regulation of neuron maturation(GO:0014041) negative regulation of neuron maturation(GO:0014043) |
| 0.0 | 0.4 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.2 | GO:0097284 | hepatocyte apoptotic process(GO:0097284) |
| 0.0 | 0.1 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
| 0.0 | 0.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.1 | GO:0043489 | RNA stabilization(GO:0043489) |
| 0.0 | 0.1 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.0 | 0.5 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.0 | 0.4 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.0 | 0.3 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393) |
| 0.0 | 0.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.1 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.0 | 0.4 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.4 | GO:0001825 | blastocyst formation(GO:0001825) |
| 0.0 | 1.0 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.0 | 0.1 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.2 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.0 | 0.0 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.0 | 0.4 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.0 | 0.3 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.9 | GO:0032526 | response to retinoic acid(GO:0032526) |
| 0.0 | 0.1 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.0 | 0.1 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.0 | 0.0 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 0.0 | 0.5 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.1 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.0 | 0.1 | GO:0048535 | lymph node development(GO:0048535) |
| 0.0 | 0.2 | GO:0002385 | organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385) |
| 0.0 | 0.1 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.0 | 0.1 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.0 | 0.6 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 1.6 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.0 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.0 | 0.4 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 0.7 | GO:0030509 | BMP signaling pathway(GO:0030509) |
| 0.0 | 0.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.2 | GO:0003170 | heart valve development(GO:0003170) |
| 0.0 | 0.6 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.0 | 0.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.6 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.0 | 0.1 | GO:0006855 | drug transmembrane transport(GO:0006855) |
| 0.0 | 0.3 | GO:0006821 | chloride transport(GO:0006821) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 11.3 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 2.5 | 9.8 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 2.1 | 8.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 2.0 | 6.0 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.9 | 7.7 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 1.7 | 8.5 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 1.3 | 4.0 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 1.3 | 3.9 | GO:0035101 | FACT complex(GO:0035101) |
| 0.9 | 10.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.9 | 3.4 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.8 | 5.6 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.8 | 3.8 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.7 | 7.5 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.7 | 11.1 | GO:0043196 | varicosity(GO:0043196) |
| 0.7 | 3.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.6 | 2.6 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.6 | 4.9 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.6 | 3.0 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.6 | 1.2 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.6 | 2.9 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.6 | 1.7 | GO:1990047 | spindle matrix(GO:1990047) |
| 0.6 | 2.3 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.6 | 5.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.6 | 1.1 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.5 | 2.7 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.5 | 3.7 | GO:0033503 | HULC complex(GO:0033503) |
| 0.5 | 4.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.5 | 6.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.5 | 4.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.5 | 3.8 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.5 | 4.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.5 | 3.7 | GO:0031415 | NatA complex(GO:0031415) |
| 0.5 | 6.4 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.5 | 2.7 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.4 | 7.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.4 | 1.2 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.4 | 1.9 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.4 | 2.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.4 | 1.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.4 | 6.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.3 | 0.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.3 | 6.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.3 | 1.7 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.3 | 3.3 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.3 | 4.6 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.3 | 10.1 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.3 | 2.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.3 | 0.6 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.3 | 1.5 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.3 | 2.4 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.3 | 5.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.3 | 5.7 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.3 | 4.9 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 1.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.2 | 1.1 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 0.6 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.2 | 1.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.2 | 4.5 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.2 | 1.5 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 0.7 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 0.2 | 9.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.2 | 1.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.2 | 0.9 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.2 | 3.0 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.2 | 0.5 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.2 | 3.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.2 | 1.4 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.2 | 1.7 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 3.2 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 1.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.1 | 1.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 1.2 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 1.3 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 1.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) carboxy-terminal domain protein kinase complex(GO:0032806) |
| 0.1 | 1.9 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.8 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.1 | 3.3 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 0.9 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.8 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.1 | 1.2 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.1 | 0.6 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.1 | 2.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 0.5 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 0.3 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 1.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 2.4 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 0.4 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.1 | 0.4 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 1.9 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 4.4 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.1 | 0.3 | GO:0097487 | multivesicular body membrane(GO:0032585) multivesicular body, internal vesicle(GO:0097487) |
| 0.1 | 1.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 0.8 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 0.9 | GO:1904949 | ATPase complex(GO:1904949) |
| 0.1 | 0.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 6.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 2.3 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 0.2 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.1 | 0.4 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.1 | 0.6 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.7 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 1.6 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 0.4 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.1 | 0.4 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 5.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 0.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 0.5 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 0.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.4 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 0.6 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.0 | 4.4 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.5 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 1.3 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 0.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.3 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.9 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 3.2 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.4 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.2 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.0 | 2.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 2.5 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.1 | GO:0031533 | mRNA cap methyltransferase complex(GO:0031533) |
| 0.0 | 0.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 0.7 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 2.4 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 1.4 | GO:0032153 | cell division site(GO:0032153) cell division site part(GO:0032155) |
| 0.0 | 1.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 2.3 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 4.6 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.0 | 0.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.4 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 1.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.2 | GO:0000800 | lateral element(GO:0000800) |
| 0.0 | 0.1 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.0 | 0.7 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 1.6 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.1 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.0 | 0.9 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 0.3 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 1.0 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 12.6 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.2 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.1 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.1 | GO:0055037 | recycling endosome(GO:0055037) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.6 | 13.8 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 2.8 | 8.5 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 2.3 | 6.9 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 1.7 | 11.7 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 1.2 | 3.7 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 1.0 | 4.2 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.9 | 5.6 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.9 | 6.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.9 | 3.6 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.8 | 3.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.8 | 2.4 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.7 | 3.0 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.7 | 6.0 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.7 | 3.7 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.7 | 4.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.7 | 2.0 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.7 | 4.6 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.6 | 3.6 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.6 | 6.0 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.5 | 1.6 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.5 | 3.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.5 | 2.1 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.5 | 1.8 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
| 0.5 | 3.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.5 | 1.4 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.4 | 1.3 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.4 | 2.6 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.4 | 4.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.4 | 2.9 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.4 | 5.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.4 | 7.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.4 | 4.0 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.4 | 2.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.4 | 2.5 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.3 | 2.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.3 | 2.0 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.3 | 1.9 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.3 | 1.2 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.3 | 1.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.3 | 8.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.3 | 5.0 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.3 | 0.6 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.3 | 1.7 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.3 | 1.1 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.3 | 1.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.3 | 1.1 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.3 | 5.0 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.3 | 1.6 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.3 | 2.1 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 1.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.2 | 6.4 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.2 | 2.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 0.9 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.2 | 8.0 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.2 | 5.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.2 | 2.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.2 | 4.5 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.2 | 0.6 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.2 | 0.8 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
| 0.2 | 3.2 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 2.0 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.2 | 3.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 1.5 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889) |
| 0.2 | 0.8 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.2 | 0.9 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.2 | 5.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.2 | 7.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 1.1 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.2 | 1.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.6 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.2 | 0.5 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.2 | 0.3 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.2 | 4.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.2 | 10.2 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 0.6 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 0.6 | GO:0004844 | mismatch base pair DNA N-glycosylase activity(GO:0000700) uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.1 | 0.7 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.7 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.1 | 43.2 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 0.4 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.1 | 2.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 4.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 4.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.9 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.1 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.1 | 1.3 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 1.0 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.1 | 0.6 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 1.0 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 0.6 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
| 0.1 | 1.5 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 0.5 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.1 | 0.6 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 0.2 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 4.4 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 7.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.1 | 2.8 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.7 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 6.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 2.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 0.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 0.3 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 4.2 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.9 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.1 | 31.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 0.8 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.1 | 0.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 2.9 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 3.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.3 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.1 | 3.6 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 0.6 | GO:0048495 | laminin-1 binding(GO:0043237) Roundabout binding(GO:0048495) |
| 0.1 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 0.3 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.1 | 1.1 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 0.5 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.1 | 0.1 | GO:0015116 | sulfate transmembrane transporter activity(GO:0015116) |
| 0.1 | 0.5 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.1 | 1.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 2.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 0.3 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.1 | 1.2 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 0.7 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 4.5 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 3.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 0.6 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 0.1 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
| 0.1 | 2.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 0.4 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 0.3 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.1 | 1.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 1.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 2.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.1 | 0.7 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.1 | 1.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 13.7 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.1 | 0.8 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 2.6 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.1 | 0.1 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.1 | 2.0 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 0.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.2 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 3.1 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 6.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 0.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.1 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.0 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.3 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 6.6 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 0.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 1.2 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 1.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.3 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.0 | 1.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.4 | GO:0015172 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.0 | 4.4 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.0 | 0.1 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.0 | 0.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.2 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.0 | 0.6 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.0 | 0.1 | GO:0004482 | mRNA (guanine-N7-)-methyltransferase activity(GO:0004482) |
| 0.0 | 0.1 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 0.0 | 0.1 | GO:0004458 | D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898) |
| 0.0 | 2.8 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.0 | 0.3 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 0.6 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 1.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.3 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.0 | 0.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 1.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.2 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 1.0 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.6 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.0 | 0.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.2 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.0 | 0.3 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.3 | GO:0015036 | disulfide oxidoreductase activity(GO:0015036) |
| 0.0 | 0.3 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.5 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 1.0 | GO:0050661 | NADP binding(GO:0050661) |
| 0.0 | 0.2 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 4.6 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 0.1 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.0 | 0.1 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 0.1 | GO:0019002 | GMP binding(GO:0019002) |
| 0.0 | 1.1 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.0 | 0.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.0 | 0.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.1 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.3 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.0 | 0.7 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.5 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.2 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 0.0 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 0.0 | 0.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.0 | 4.4 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.3 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.1 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 0.5 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
| 0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.5 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 1.9 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 3.0 | GO:0003682 | chromatin binding(GO:0003682) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 9.0 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.4 | 3.5 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.3 | 9.3 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.3 | 2.3 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.2 | 8.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.2 | 5.3 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
| 0.2 | 3.3 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.2 | 1.1 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 1.0 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 4.5 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 4.0 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 0.7 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 5.7 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 5.5 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.1 | 5.1 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.1 | 3.5 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.1 | 3.9 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.1 | 1.7 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.9 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 6.8 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.0 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.5 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.1 | 0.5 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.6 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 1.1 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.3 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 1.8 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.9 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.0 | 0.6 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 1.1 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.0 | 1.9 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.4 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.9 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.4 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 4.9 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.0 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 0.8 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.0 | 0.9 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 0.2 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 0.4 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.2 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 1.1 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.3 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.9 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.2 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.3 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.3 | 10.1 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.3 | 4.5 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.3 | 2.4 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.3 | 4.2 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
| 0.3 | 5.0 | REACTOME_SOS_MEDIATED_SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.3 | 4.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.2 | 6.4 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.2 | 10.2 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.2 | 1.5 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.2 | 8.2 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 2.7 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.2 | 12.7 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.2 | 14.3 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.2 | 2.8 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 3.0 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.2 | 3.5 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.2 | 3.1 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.2 | 16.4 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 2.4 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 2.3 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.1 | 1.1 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 11.9 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 17.9 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.9 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 3.0 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 0.5 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 1.4 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 1.7 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 18.7 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 1.2 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.1 | 1.3 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 1.9 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 0.3 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.1 | 1.8 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 1.3 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.1 | 1.3 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 1.2 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 0.6 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 0.6 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 2.7 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.7 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 2.9 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.1 | 1.6 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 1.1 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 1.5 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 1.2 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.3 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.7 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 2.1 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 2.0 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.7 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.2 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.2 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.2 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 0.8 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.2 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.8 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.1 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.0 | 1.6 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.2 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.2 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.1 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.3 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.2 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.1 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.7 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.1 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.0 | 0.7 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 2.3 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.1 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
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