Motif ID: Zfp110

Z-value: 3.212


Transcription factors associated with Zfp110:

Gene SymbolEntrez IDGene Name
Zfp110 ENSMUSG00000058638.7 Zfp110

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp110mm10_v2_chr7_+_12834743_128348110.401.0e-02Click!


Activity profile for motif Zfp110.

activity profile for motif Zfp110


Sorted Z-values histogram for motif Zfp110

Sorted Z-values for motif Zfp110



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp110

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_61297069 50.077 ENSMUST00000179346.1
 Gm21060
predicted gene, 21060
chr17_+_16972910 48.473 ENSMUST00000071374.5
 BC002059
cDNA sequence BC002059
chr5_-_110046486 42.242 ENSMUST00000167969.1
 Gm17655
predicted gene, 17655
chr12_-_20900867 31.981 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chr8_-_69373383 29.807 ENSMUST00000072427.4
 Gm10033
predicted gene 10033
chr12_-_23780265 28.925 ENSMUST00000072014.4
 Gm10330
predicted gene 10330
chr2_+_177508570 27.698 ENSMUST00000108940.2
 Gm14403
predicted gene 14403
chr17_+_21691860 27.209 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr17_+_21690766 26.263 ENSMUST00000097384.1
 Gm10509
predicted gene 10509
chr10_+_82378593 24.994 ENSMUST00000165906.1
 Gm4924
predicted gene 4924
chr7_-_42578588 22.643 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr2_+_176236860 21.004 ENSMUST00000166464.1
 2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr2_-_176917518 20.711 ENSMUST00000108931.2
 Gm14296
predicted gene 14296
chr2_-_175131864 20.663 ENSMUST00000108929.2
 Gm14399
predicted gene 14399
chr13_-_66851513 17.570 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr17_+_22689771 15.749 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr13_+_65512678 14.627 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr13_-_66227573 14.447 ENSMUST00000167981.2
 Gm10772
predicted gene 10772
chr8_-_69373914 11.227 ENSMUST00000095282.1
 Gm10311
predicted gene 10311
chr13_-_66852017 11.197 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chrX_-_93632113 4.093 ENSMUST00000006856.2
 Pola1
polymerase (DNA directed), alpha 1
chr6_+_65671590 3.333 ENSMUST00000054351.4
 Ndnf
neuron-derived neurotrophic factor
chr4_-_94979063 2.790 ENSMUST00000075872.3
 Mysm1
myb-like, SWIRM and MPN domains 1
chr7_+_92062392 2.563 ENSMUST00000098308.2
 Dlg2
discs, large homolog 2 (Drosophila)
chr2_-_59160644 2.192 ENSMUST00000077687.5
 Ccdc148
coiled-coil domain containing 148
chr9_-_4309432 1.949 ENSMUST00000051589.7
 Aasdhppt
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr10_+_69925484 1.864 ENSMUST00000182692.1
ENSMUST00000092433.5
 Ank3

ankyrin 3, epithelial

chr8_-_17535251 1.849 ENSMUST00000082104.6
 Csmd1
CUB and Sushi multiple domains 1
chr9_+_4309719 1.669 ENSMUST00000049648.7
 Kbtbd3
kelch repeat and BTB (POZ) domain containing 3
chr2_-_150255591 1.294 ENSMUST00000063463.5
 Gm21994
predicted gene 21994
chr6_+_17306335 0.991 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr2_+_59160838 0.843 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
 Pkp4


plakophilin 4


chr14_-_55116935 0.744 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr2_+_59160884 0.652 ENSMUST00000037903.8
 Pkp4
plakophilin 4
chr7_+_24271568 0.586 ENSMUST00000032696.6
 Zfp93
zinc finger protein 93
chr2_-_119541513 0.435 ENSMUST00000171024.1
 Exd1
exonuclease 3'-5' domain containing 1
chr4_+_43669266 0.285 ENSMUST00000107864.1
 Tmem8b
transmembrane protein 8B
chr15_-_94589870 0.266 ENSMUST00000023087.6
ENSMUST00000152590.1
 Twf1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr15_-_103215285 0.162 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chr8_-_105933832 0.120 ENSMUST00000034368.6
 Ctrl
chymotrypsin-like
chr3_-_108536466 0.107 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
 5330417C22Rik


RIKEN cDNA 5330417C22 gene


chr19_+_8741669 0.060 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
 Stx5a


syntaxin 5A


chr6_+_17306415 0.044 ENSMUST00000150901.1
 Cav1
caveolin 1, caveolae protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0006272 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.7 2.8 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6 1.9 GO:0006553 lysine metabolic process(GO:0006553)
0.4 3.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) vascular wound healing(GO:0061042)
0.2 1.0 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 2.6 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 1.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.8 GO:0001964 startle response(GO:0001964)
0.0 1.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 112.9 GO:0006355 regulation of transcription, DNA-templated(GO:0006355)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.1 2.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 252.4 GO:0005575 cellular_component(GO:0005575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.2 1.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 2.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 91.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 2.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.0 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 3.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.9 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis