Motif ID: Zfp263
Z-value: 0.899
Transcription factors associated with Zfp263:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zfp263 | ENSMUSG00000022529.5 | Zfp263 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp263 | mm10_v2_chr16_+_3744089_3744145 | 0.24 | 1.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.2 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 1.8 | 5.5 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
| 1.2 | 4.7 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 1.2 | 3.5 | GO:0072194 | sensory perception of touch(GO:0050975) kidney smooth muscle tissue development(GO:0072194) |
| 1.1 | 3.3 | GO:0043379 | memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 1.0 | 5.2 | GO:1903587 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
| 0.9 | 6.5 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.9 | 7.2 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.9 | 4.4 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.9 | 1.7 | GO:0003274 | endocardial cushion fusion(GO:0003274) |
| 0.8 | 3.0 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 0.7 | 4.4 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.7 | 2.8 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.7 | 2.0 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.7 | 2.6 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 0.6 | 3.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.6 | 1.8 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
| 0.6 | 1.8 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203) |
| 0.6 | 2.2 | GO:2000546 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.5 | 2.1 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.5 | 1.0 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.4 | 2.6 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.4 | 2.6 | GO:0071630 | trophectodermal cellular morphogenesis(GO:0001831) nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.4 | 8.6 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.4 | 2.3 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.4 | 2.2 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.4 | 2.6 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.4 | 1.4 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.4 | 0.7 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.4 | 1.1 | GO:1904347 | intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770) |
| 0.3 | 1.0 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.3 | 0.7 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 0.3 | 1.0 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.3 | 1.7 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.3 | 2.3 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.3 | 1.2 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.3 | 0.9 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
| 0.3 | 2.3 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 0.3 | 1.3 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.3 | 1.3 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.3 | 1.0 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.3 | 3.0 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.2 | 1.0 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.2 | 0.7 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
| 0.2 | 0.7 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 0.2 | 1.6 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.2 | 1.6 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.2 | 1.8 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
| 0.2 | 1.1 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.2 | 2.0 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.2 | 1.1 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.2 | 1.5 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 1.9 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.2 | 0.6 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.2 | 1.9 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.2 | 0.6 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.2 | 0.6 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.2 | 1.4 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.2 | 1.7 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.2 | 1.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.2 | 5.6 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.2 | 0.6 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
| 0.2 | 2.0 | GO:0032682 | negative regulation of chemokine production(GO:0032682) |
| 0.2 | 0.9 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.2 | 1.2 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.2 | 0.9 | GO:0006537 | glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543) |
| 0.2 | 0.7 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 0.2 | 1.2 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.2 | 3.0 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.2 | 0.7 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.2 | 1.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.2 | 0.8 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.2 | 0.6 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.2 | 1.6 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.2 | 1.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 0.9 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.2 | 0.6 | GO:1904048 | regulation of spontaneous neurotransmitter secretion(GO:1904048) |
| 0.2 | 0.3 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.1 | 1.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 2.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 0.5 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.1 | 1.7 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.1 | 0.6 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.1 | 0.5 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.1 | 0.1 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) |
| 0.1 | 0.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.1 | 0.5 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.1 | 1.1 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 0.5 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 0.5 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.1 | 0.5 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.1 | 4.5 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.1 | 0.4 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
| 0.1 | 1.1 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.1 | 1.7 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.3 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 0.1 | 0.8 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.1 | 1.8 | GO:0006415 | translational termination(GO:0006415) |
| 0.1 | 1.4 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.1 | 0.3 | GO:0090004 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.1 | 1.5 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
| 0.1 | 1.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.4 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.1 | 0.8 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 1.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.6 | GO:0031034 | myosin filament assembly(GO:0031034) |
| 0.1 | 0.7 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.1 | 0.4 | GO:0014831 | gastro-intestinal system smooth muscle contraction(GO:0014831) |
| 0.1 | 0.3 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.1 | 1.4 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.9 | GO:0060088 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) auditory receptor cell stereocilium organization(GO:0060088) |
| 0.1 | 1.2 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.2 | GO:0072393 | microtubule anchoring at microtubule organizing center(GO:0072393) |
| 0.1 | 0.5 | GO:0051775 | response to redox state(GO:0051775) |
| 0.1 | 0.3 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.1 | 0.8 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 1.5 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.1 | 1.0 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 0.6 | GO:0048715 | negative regulation of oligodendrocyte differentiation(GO:0048715) |
| 0.1 | 0.8 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 6.8 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 2.2 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 0.4 | GO:1904923 | regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) |
| 0.1 | 0.2 | GO:1990859 | cellular response to endothelin(GO:1990859) |
| 0.1 | 0.7 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 0.5 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.1 | 1.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 3.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 0.9 | GO:0060746 | parental behavior(GO:0060746) |
| 0.1 | 0.4 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.1 | 2.0 | GO:0050856 | regulation of T cell receptor signaling pathway(GO:0050856) |
| 0.1 | 0.5 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 0.4 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 0.1 | 0.2 | GO:2000630 | positive regulation of miRNA metabolic process(GO:2000630) |
| 0.1 | 0.3 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
| 0.1 | 0.2 | GO:0070417 | cellular response to cold(GO:0070417) |
| 0.1 | 0.2 | GO:0060126 | hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126) |
| 0.1 | 1.4 | GO:0030803 | negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) |
| 0.1 | 0.4 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 0.3 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.3 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.1 | 0.6 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.1 | 0.2 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 0.6 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.8 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.0 | 0.2 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 0.7 | GO:0048679 | regulation of axon regeneration(GO:0048679) |
| 0.0 | 0.3 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.0 | 0.5 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.0 | 0.4 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
| 0.0 | 0.7 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 0.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.1 | GO:0014735 | regulation of muscle atrophy(GO:0014735) |
| 0.0 | 0.2 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.0 | 0.4 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.7 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.8 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.0 | 0.4 | GO:0099515 | actin filament-based transport(GO:0099515) |
| 0.0 | 0.2 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.0 | 0.7 | GO:2000404 | regulation of T cell migration(GO:2000404) |
| 0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.4 | GO:0042094 | interleukin-2 biosynthetic process(GO:0042094) |
| 0.0 | 0.2 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.0 | 0.2 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.0 | 0.2 | GO:0006678 | glucosylceramide metabolic process(GO:0006678) |
| 0.0 | 0.1 | GO:1903860 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) |
| 0.0 | 0.4 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.0 | 0.8 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.0 | 0.2 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.0 | 0.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.0 | 0.5 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.0 | 0.1 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
| 0.0 | 0.5 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.0 | 0.3 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.0 | 0.4 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.0 | 0.2 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.0 | 0.3 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 0.1 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.0 | 0.6 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.0 | 0.5 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.0 | 0.5 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.3 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.0 | 0.0 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) |
| 0.0 | 0.3 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 1.1 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.1 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.4 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.6 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.0 | 2.7 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.7 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.0 | 0.0 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.0 | 0.4 | GO:2000772 | regulation of cellular senescence(GO:2000772) |
| 0.0 | 0.2 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.2 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 0.2 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.0 | 0.8 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
| 0.0 | 0.4 | GO:0040018 | positive regulation of multicellular organism growth(GO:0040018) |
| 0.0 | 0.0 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.0 | 0.5 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.0 | 0.1 | GO:1904861 | excitatory synapse assembly(GO:1904861) |
| 0.0 | 1.0 | GO:0015992 | proton transport(GO:0015992) |
| 0.0 | 0.0 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) progesterone secretion(GO:0042701) cerebellum vasculature development(GO:0061300) |
| 0.0 | 0.2 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
| 0.0 | 0.4 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 5.8 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.9 | 4.7 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.7 | 4.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.6 | 1.7 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.6 | 5.1 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.5 | 1.5 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.5 | 1.8 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.4 | 6.5 | GO:0043196 | varicosity(GO:0043196) |
| 0.4 | 2.6 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.3 | 1.0 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.3 | 4.9 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 2.1 | GO:0042825 | TAP complex(GO:0042825) |
| 0.3 | 3.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.3 | 1.8 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 0.7 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.2 | 3.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.2 | 0.9 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.2 | 0.9 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.2 | 0.5 | GO:0098842 | postsynaptic early endosome(GO:0098842) |
| 0.2 | 1.7 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 2.5 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 1.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.2 | 0.8 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 2.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 2.3 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 1.4 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.1 | 0.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 1.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 1.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 1.0 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 1.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.5 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.1 | 0.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.3 | GO:0031417 | NatC complex(GO:0031417) |
| 0.1 | 2.4 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 0.4 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 0.4 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.1 | 0.7 | GO:0097413 | Lewy body(GO:0097413) |
| 0.1 | 2.3 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 0.3 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.1 | 2.0 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 1.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.2 | GO:0044299 | C-fiber(GO:0044299) |
| 0.1 | 0.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 1.2 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 4.7 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.1 | 0.3 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 0.1 | 1.2 | GO:0009986 | cell surface(GO:0009986) |
| 0.1 | 0.6 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.6 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
| 0.1 | 0.9 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.1 | 0.9 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 2.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.8 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 6.7 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 2.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 3.3 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 0.1 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.0 | 2.1 | GO:0030117 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 0.0 | 0.3 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.0 | 0.4 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 0.2 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.0 | 4.4 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 2.7 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 1.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 9.6 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 3.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.3 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 0.7 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 2.4 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.8 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.0 | 0.8 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 1.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 1.4 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.7 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.8 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 2.5 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.7 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.2 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 1.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.1 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.1 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 0.1 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.9 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.1 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 3.7 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.4 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.2 | GO:0044217 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.0 | 0.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.1 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.0 | 1.5 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.1 | GO:0097228 | sperm principal piece(GO:0097228) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 8.8 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 1.0 | 2.9 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.9 | 2.6 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.8 | 3.0 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.7 | 2.0 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.6 | 1.8 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.5 | 1.6 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.5 | 0.5 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.5 | 2.1 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980) |
| 0.5 | 6.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.4 | 1.7 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.4 | 5.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.4 | 2.5 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.4 | 1.2 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
| 0.4 | 1.5 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.3 | 2.9 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.3 | 0.9 | GO:0016901 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 0.3 | 1.9 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.3 | 1.8 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.3 | 1.8 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.3 | 0.9 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.3 | 3.0 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.3 | 3.3 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.3 | 1.0 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.3 | 7.4 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.2 | 0.7 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.2 | 0.7 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.2 | 3.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.2 | 1.8 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.2 | 1.7 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 0.6 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.2 | 0.6 | GO:0004534 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534) |
| 0.2 | 0.6 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.2 | 1.0 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.2 | 2.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.2 | 0.8 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.2 | 1.4 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.2 | 1.9 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 1.1 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 1.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.2 | 0.9 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.2 | 0.7 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.2 | 1.5 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.2 | 0.6 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) |
| 0.1 | 0.6 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.1 | 0.7 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.1 | 6.6 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 1.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 1.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 2.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.1 | 0.5 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.1 | 1.0 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.1 | 0.5 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.1 | 1.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.5 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.1 | 2.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 0.5 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 0.5 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 0.1 | 0.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.1 | 0.4 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.1 | 0.4 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 7.6 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.1 | 0.9 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 1.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 1.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 0.2 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 0.1 | 0.9 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 0.5 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.1 | 0.8 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 0.7 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.1 | 0.9 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.1 | 0.7 | GO:0099604 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
| 0.1 | 0.5 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.1 | 0.3 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.1 | 0.4 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.6 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.7 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 1.6 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.1 | 0.9 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 0.2 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.3 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 0.2 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.1 | 0.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 1.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 0.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.2 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.0 | 0.9 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.0 | 2.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.2 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.0 | 0.8 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 1.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.3 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.7 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
| 0.0 | 2.3 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.5 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 4.0 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 1.2 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 2.6 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 1.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.7 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 2.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.3 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.0 | 1.4 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 4.9 | GO:0004175 | endopeptidase activity(GO:0004175) |
| 0.0 | 0.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.1 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.6 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 0.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 1.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.3 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 3.1 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.0 | 1.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 1.8 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.4 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.2 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.0 | 0.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 1.3 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.3 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.6 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.1 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 0.0 | 0.4 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.9 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.9 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.0 | 0.0 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.0 | 1.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.1 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 0.2 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 4.5 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.1 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.5 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 6.1 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.1 | 0.3 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 1.0 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.1 | 2.5 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 1.0 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 2.6 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 3.7 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
| 0.1 | 1.5 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.1 | 0.8 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 0.8 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 3.1 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 2.0 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 1.9 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 1.8 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.0 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.0 | 0.8 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
| 0.0 | 2.1 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.7 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 0.5 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.4 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.5 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.6 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.3 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 2.1 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.7 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 0.2 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 3.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.7 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.1 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.3 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.1 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.3 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.5 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.3 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 0.2 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.3 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 1.2 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.6 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 0.4 | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.3 | 9.6 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.3 | 6.5 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.2 | 1.5 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.2 | 3.0 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 2.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 1.7 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 1.9 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 2.3 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 1.9 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 2.6 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 2.4 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 4.7 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 2.3 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 3.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.3 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.8 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 0.3 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.1 | 0.7 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 2.7 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.7 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 3.9 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.1 | 0.6 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 1.0 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 1.4 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.1 | 0.9 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.2 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 0.6 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.7 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.8 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.6 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.9 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 3.2 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 4.1 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.3 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.2 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.0 | 0.3 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 0.2 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.6 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.8 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.7 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.7 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.6 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 1.3 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.8 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.5 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.1 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 1.2 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.3 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.0 | 1.6 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.2 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.0 | 0.2 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 0.3 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
