Motif ID: Zkscan3

Z-value: 0.254


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.287.9e-02Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_24985840 0.695 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr18_+_61105844 0.525 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr6_-_122856151 0.509 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr18_+_82554463 0.362 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
 Mbp










myelin basic protein










chr11_-_75422524 0.325 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr8_+_31091593 0.324 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr8_+_94810446 0.295 ENSMUST00000034232.1
 Ccl17
chemokine (C-C motif) ligand 17
chr13_-_32851176 0.258 ENSMUST00000091668.5
ENSMUST00000076352.6
 Serpinb1a

serine (or cysteine) peptidase inhibitor, clade B, member 1a

chr8_+_70616816 0.234 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr8_-_105758570 0.213 ENSMUST00000155038.2
ENSMUST00000013294.9
 Gfod2

glucose-fructose oxidoreductase domain containing 2

chr8_-_116978908 0.211 ENSMUST00000070577.5
 1700030J22Rik
RIKEN cDNA 1700030J22 gene
chr8_+_106893616 0.201 ENSMUST00000047629.5
 Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr13_-_38658991 0.200 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr2_-_66634952 0.198 ENSMUST00000100064.2
ENSMUST00000100063.2
 Scn9a

sodium channel, voltage-gated, type IX, alpha

chr11_-_75422586 0.197 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr4_+_139192899 0.189 ENSMUST00000102508.3
ENSMUST00000131912.1
ENSMUST00000102507.3
 Capzb


capping protein (actin filament) muscle Z-line, beta


chr13_-_19395728 0.179 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr11_-_102365111 0.172 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr1_-_40790642 0.165 ENSMUST00000039672.5
 Mfsd9
major facilitator superfamily domain containing 9
chr8_-_106893515 0.154 ENSMUST00000176090.1
 Chtf8
CTF8, chromosome transmission fidelity factor 8
chr7_-_81345189 0.141 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr8_-_106893581 0.139 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
 Chtf8



CTF8, chromosome transmission fidelity factor 8



chr1_+_180942452 0.139 ENSMUST00000027800.8
 Tmem63a
transmembrane protein 63a
chr2_+_31670714 0.135 ENSMUST00000038474.7
ENSMUST00000137156.1
 Exosc2

exosome component 2

chr8_-_124897685 0.131 ENSMUST00000098312.2
 Exoc8
exocyst complex component 8
chr7_+_101896340 0.122 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr2_+_156613664 0.122 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr17_-_35673517 0.121 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
 Gtf2h4



general transcription factor II H, polypeptide 4



chr2_+_121295437 0.114 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr6_+_125552948 0.112 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr17_-_35673738 0.105 ENSMUST00000001565.8
 Gtf2h4
general transcription factor II H, polypeptide 4
chr13_+_42709482 0.101 ENSMUST00000066928.5
ENSMUST00000148891.1
 Phactr1

phosphatase and actin regulator 1

chr2_+_32646586 0.082 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr9_+_114688782 0.080 ENSMUST00000047404.6
 Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr2_+_104095796 0.078 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr9_+_108648720 0.077 ENSMUST00000098384.2
 Gm10621
predicted gene 10621
chr5_+_117976761 0.077 ENSMUST00000035579.6
 Fbxo21
F-box protein 21
chr19_+_6276725 0.075 ENSMUST00000025684.3
 Ehd1
EH-domain containing 1
chr4_+_63544747 0.065 ENSMUST00000035301.6
 Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr3_-_95687846 0.064 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
 Adamtsl4


ADAMTS-like 4


chr3_+_146500071 0.063 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr17_+_46110982 0.061 ENSMUST00000024763.3
ENSMUST00000123646.1
 Mrps18a

mitochondrial ribosomal protein S18A

chr18_-_34651703 0.061 ENSMUST00000025228.5
ENSMUST00000133181.1
 Cdc23

CDC23 cell division cycle 23

chr7_-_98178254 0.055 ENSMUST00000040971.7
 Capn5
calpain 5
chr13_+_73467197 0.050 ENSMUST00000022099.8
 Lpcat1
lysophosphatidylcholine acyltransferase 1
chr6_+_127453667 0.046 ENSMUST00000112193.1
 Parp11
poly (ADP-ribose) polymerase family, member 11
chr6_+_127453705 0.042 ENSMUST00000039680.5
 Parp11
poly (ADP-ribose) polymerase family, member 11
chr3_+_146499850 0.038 ENSMUST00000118280.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr7_-_27228605 0.038 ENSMUST00000003850.7
 Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr11_-_88851462 0.037 ENSMUST00000107903.1
 Akap1
A kinase (PRKA) anchor protein 1
chr14_+_51893610 0.037 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr15_-_3979432 0.035 ENSMUST00000022791.8
 Fbxo4
F-box protein 4
chr19_-_10869757 0.033 ENSMUST00000120524.1
ENSMUST00000025645.7
 Tmem132a

transmembrane protein 132A

chr14_+_57424054 0.030 ENSMUST00000122063.1
 Ift88
intraflagellar transport 88
chr8_+_71396853 0.027 ENSMUST00000002473.8
 Babam1
BRISC and BRCA1 A complex member 1
chrX_-_75874536 0.025 ENSMUST00000033547.7
 Pls3
plastin 3 (T-isoform)
chr1_+_58795371 0.023 ENSMUST00000027189.8
 Casp8
caspase 8
chr2_+_155775333 0.021 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr7_+_126759601 0.016 ENSMUST00000050201.4
ENSMUST00000057669.9
 Mapk3

mitogen-activated protein kinase 3

chr7_-_127020321 0.014 ENSMUST00000032918.2
 Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr5_-_73338580 0.014 ENSMUST00000087195.5
 Ociad2
OCIA domain containing 2
chr1_-_39651165 0.012 ENSMUST00000053355.4
 Creg2
cellular repressor of E1A-stimulated genes 2
chr12_+_76533540 0.001 ENSMUST00000075249.4
 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.4 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway