Motif ID: Ar

Z-value: 1.065


Transcription factors associated with Ar:

Gene SymbolEntrez IDGene Name
Ar ENSMUSG00000046532.7 Ar



Activity profile for motif Ar.

activity profile for motif Ar


Sorted Z-values histogram for motif Ar

Sorted Z-values for motif Ar



Network of associatons between targets according to the STRING database.



First level regulatory network of Ar

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 6.107 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 6.058 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr4_-_136892867 6.003 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr10_-_117282262 5.963 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr3_+_117575268 5.500 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr8_+_94179089 4.552 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr12_+_74297474 4.463 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr3_-_113577743 4.226 ENSMUST00000067980.5
 Amy1
amylase 1, salivary
chr12_-_25096080 4.104 ENSMUST00000020974.6
 Id2
inhibitor of DNA binding 2
chr3_-_113574758 3.910 ENSMUST00000106540.1
 Amy1
amylase 1, salivary
chr19_+_8664005 3.828 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr3_-_113574242 3.763 ENSMUST00000142505.2
 Amy1
amylase 1, salivary
chr17_+_56764738 3.480 ENSMUST00000007747.8
 Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr13_-_37049203 3.013 ENSMUST00000037491.8
 F13a1
coagulation factor XIII, A1 subunit
chr14_-_7483762 2.643 ENSMUST00000164366.1
 Gm3752
predicted gene 3752
chr14_-_5455467 2.583 ENSMUST00000180867.1
 Gm3194
predicted gene 3194
chr8_+_95703037 2.543 ENSMUST00000073139.7
ENSMUST00000080666.7
 Ndrg4

N-myc downstream regulated gene 4

chrX_-_162565514 2.463 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr17_-_35175995 2.430 ENSMUST00000173324.1
 Aif1
allograft inflammatory factor 1
chr19_+_4099998 2.345 ENSMUST00000049658.7
 Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 130 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 12.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 9.7 GO:0016052 carbohydrate catabolic process(GO:0016052)
2.0 6.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.9 6.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.7 4.6 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.8 4.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.3 3.9 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 3.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.8 3.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.0 3.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 2.9 GO:0008033 tRNA processing(GO:0008033)
0.2 2.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.8 2.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.6 2.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.8 2.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.5 2.3 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 2.3 GO:0015914 phospholipid transport(GO:0015914)
0.7 2.2 GO:0060166 olfactory pit development(GO:0060166)
0.1 2.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.5 2.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.1 12.2 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 11.6 GO:0072562 blood microparticle(GO:0072562)
0.0 10.8 GO:0005615 extracellular space(GO:0005615)
1.2 6.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 3.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 3.4 GO:0005925 focal adhesion(GO:0005925)
0.0 2.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.1 GO:0002080 acrosomal membrane(GO:0002080)
0.5 2.0 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.7 GO:0097225 sperm midpiece(GO:0097225)
0.4 1.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.6 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 1.4 GO:0005584 collagen type I trimer(GO:0005584)
0.1 1.4 GO:0097431 mitotic spindle pole(GO:0097431)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 12.2 GO:0045504 dynein heavy chain binding(GO:0045504)
4.0 11.9 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
2.0 6.0 GO:0003796 lysozyme activity(GO:0003796)
1.3 3.9 GO:0031403 lithium ion binding(GO:0031403)
0.8 3.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 3.4 GO:0005507 copper ion binding(GO:0005507)
1.0 3.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.8 3.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 2.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.8 2.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 2.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 2.3 GO:0005537 mannose binding(GO:0005537)
0.3 2.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.5 2.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.4 2.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.7 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 2.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.8 PID_FOXO_PATHWAY FoxO family signaling
0.2 3.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.0 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.2 1.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.4 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 5.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.9 5.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 3.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.5 3.0 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.4 3.0 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.0 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 2.9 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 2.5 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.4 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.9 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1