Motif ID: Arid3a

Z-value: 0.490


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927330_799273700.019.4e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_3583191 2.788 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr3_-_85741389 2.241 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr15_-_3583146 1.704 ENSMUST00000110698.2
 Ghr
growth hormone receptor
chr4_+_139923349 1.583 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr7_+_66365905 1.487 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr16_+_43510267 1.257 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr3_-_116129615 1.192 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr4_-_87806296 1.083 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr4_-_87806276 1.055 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_+_3532554 1.021 ENSMUST00000168560.1
 Cldn20
claudin 20
chrX_-_141474034 0.865 ENSMUST00000101205.2
 Col4a6
collagen, type IV, alpha 6
chr9_+_114731177 0.770 ENSMUST00000035007.8
 Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr6_+_143285988 0.740 ENSMUST00000160951.1
 D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr5_-_70842617 0.646 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr10_+_79996479 0.617 ENSMUST00000132517.1
 Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr2_-_175327598 0.585 ENSMUST00000109050.2
 Gm4631
predicted gene 4631
chr18_+_35770318 0.575 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr7_+_140941550 0.558 ENSMUST00000079403.4
 Athl1
ATH1, acid trehalase-like 1 (yeast)
chr12_-_4769217 0.554 ENSMUST00000053458.5
 Fam228b
family with sequence similarity 228, member B
chr7_+_51878967 0.517 ENSMUST00000051912.6
 Gas2
growth arrest specific 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 4.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 2.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.6 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.3 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.3 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.2 0.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.5 GO:0017046 peptide hormone binding(GO:0017046)
0.3 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.4 GO:0005536 glucose binding(GO:0005536)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 1.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID_IL23_PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol