Motif ID: Arid3a

Z-value: 0.490


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927330_799273700.019.4e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_3583191 2.788 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr3_-_85741389 2.241 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr15_-_3583146 1.704 ENSMUST00000110698.2
 Ghr
growth hormone receptor
chr4_+_139923349 1.583 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr7_+_66365905 1.487 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr16_+_43510267 1.257 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr3_-_116129615 1.192 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr4_-_87806296 1.083 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr4_-_87806276 1.055 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_+_3532554 1.021 ENSMUST00000168560.1
 Cldn20
claudin 20
chrX_-_141474034 0.865 ENSMUST00000101205.2
 Col4a6
collagen, type IV, alpha 6
chr9_+_114731177 0.770 ENSMUST00000035007.8
 Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr6_+_143285988 0.740 ENSMUST00000160951.1
 D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr5_-_70842617 0.646 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr10_+_79996479 0.617 ENSMUST00000132517.1
 Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr2_-_175327598 0.585 ENSMUST00000109050.2
 Gm4631
predicted gene 4631
chr18_+_35770318 0.575 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr7_+_140941550 0.558 ENSMUST00000079403.4
 Athl1
ATH1, acid trehalase-like 1 (yeast)
chr12_-_4769217 0.554 ENSMUST00000053458.5
 Fam228b
family with sequence similarity 228, member B
chr7_+_51878967 0.517 ENSMUST00000051912.6
 Gas2
growth arrest specific 2
chr7_+_51879041 0.493 ENSMUST00000107591.2
 Gas2
growth arrest specific 2
chr11_-_80377975 0.489 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
 5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr1_+_60181495 0.452 ENSMUST00000160834.1
 Nbeal1
neurobeachin like 1
chr1_+_179961110 0.450 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr14_+_120275669 0.434 ENSMUST00000088419.6
ENSMUST00000167459.1
 Mbnl2

muscleblind-like 2

chr17_+_40561498 0.428 ENSMUST00000167713.1
ENSMUST00000097324.3
 Gm5494
Gm5494
predicted gene 5494
predicted gene 5494
chr15_-_50882806 0.425 ENSMUST00000184885.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr2_-_32982007 0.410 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr11_-_116654245 0.402 ENSMUST00000021166.5
 Cygb
cytoglobin
chr2_+_3770673 0.401 ENSMUST00000177037.1
 Fam107b
family with sequence similarity 107, member B
chr4_+_58943575 0.381 ENSMUST00000107554.1
 Zkscan16
zinc finger with KRAB and SCAN domains 16
chr16_-_57292845 0.356 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
 Tmem30c


transmembrane protein 30C


chr7_+_102223021 0.353 ENSMUST00000156529.1
ENSMUST00000138479.1
ENSMUST00000126914.1
ENSMUST00000033292.7
ENSMUST00000146559.1
 Pgap2




post-GPI attachment to proteins 2




chr3_-_146495115 0.347 ENSMUST00000093951.2
 Spata1
spermatogenesis associated 1
chr1_+_179960472 0.342 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr1_-_150392719 0.320 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr1_+_150392794 0.315 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr15_+_83563571 0.312 ENSMUST00000047419.6
 Tspo
translocator protein
chr3_-_135608221 0.305 ENSMUST00000132668.1
 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr17_-_78684262 0.281 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr1_-_158958367 0.280 ENSMUST00000159861.2
 Pappa2
pappalysin 2
chr11_+_87664274 0.271 ENSMUST00000092800.5
 Rnf43
ring finger protein 43
chr7_+_118597295 0.268 ENSMUST00000121715.1
ENSMUST00000098088.4
 Tmc5

transmembrane channel-like gene family 5

chr3_+_30602056 0.255 ENSMUST00000047502.7
 Mynn
myoneurin
chr1_-_24612700 0.247 ENSMUST00000088336.1
 Gm10222
predicted gene 10222
chr15_+_100334929 0.239 ENSMUST00000075420.4
 Mettl7a3
methyltransferase like 7A3
chrX_+_163911401 0.234 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr3_+_32436376 0.222 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr3_+_95282897 0.218 ENSMUST00000039537.7
ENSMUST00000107187.2
 Fam63a

family with sequence similarity 63, member A

chr10_+_69533803 0.218 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
 Ank3


ankyrin 3, epithelial


chr9_-_42457594 0.211 ENSMUST00000125995.1
 Tbcel
tubulin folding cofactor E-like
chr9_+_54538984 0.207 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr9_+_108392820 0.207 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr3_+_32436151 0.206 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr12_+_65225513 0.201 ENSMUST00000046331.4
 Wdr20b
WD repeat domain 20b
chr2_-_165388245 0.194 ENSMUST00000103084.3
 Zfp334
zinc finger protein 334
chr19_+_58728887 0.181 ENSMUST00000048644.5
 Pnliprp1
pancreatic lipase related protein 1
chr10_-_100589205 0.167 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr10_+_69533761 0.163 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr6_+_29361410 0.159 ENSMUST00000156163.1
 Calu
calumenin
chr1_+_155158703 0.150 ENSMUST00000027743.7
 Stx6
syntaxin 6
chr18_-_6241486 0.147 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr10_-_13324160 0.142 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2
chr6_+_51544513 0.134 ENSMUST00000179365.1
ENSMUST00000114439.1
 Snx10

sorting nexin 10

chr7_+_27452417 0.133 ENSMUST00000108357.1
 Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr4_-_108071327 0.130 ENSMUST00000106701.1
 Scp2
sterol carrier protein 2, liver
chr4_+_134930898 0.124 ENSMUST00000030622.2
 Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr18_-_73754457 0.112 ENSMUST00000041138.2
 Elac1
elaC homolog 1 (E. coli)
chr7_+_99594605 0.109 ENSMUST00000162290.1
 Arrb1
arrestin, beta 1
chr2_-_176144697 0.109 ENSMUST00000178872.1
 Gm2004
predicted gene 2004
chr1_+_171113918 0.104 ENSMUST00000129651.1
ENSMUST00000151340.1
 1700009P17Rik

RIKEN cDNA 1700009P17 gene

chr2_+_176807362 0.104 ENSMUST00000179435.1
 Gm14295
predicted gene 14295
chr18_-_6241470 0.103 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr2_+_177009681 0.099 ENSMUST00000178182.1
 Gm14419
predicted gene 14419
chr4_-_25281752 0.098 ENSMUST00000038705.7
 Ufl1
UFM1 specific ligase 1
chr10_-_13324250 0.078 ENSMUST00000105543.1
 Phactr2
phosphatase and actin regulator 2
chr5_-_23616528 0.078 ENSMUST00000088392.4
 Srpk2
serine/arginine-rich protein specific kinase 2
chr14_+_47472547 0.077 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
 Fbxo34


F-box protein 34


chr14_+_47472628 0.075 ENSMUST00000095941.2
 Fbxo34
F-box protein 34
chr7_-_121981669 0.065 ENSMUST00000057576.7
 Cog7
component of oligomeric golgi complex 7
chr10_-_58675631 0.058 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr10_+_120227109 0.058 ENSMUST00000130198.1
 Llph
LLP homolog, long-term synaptic facilitation (Aplysia)
chr15_+_99006056 0.056 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chrX_+_162901226 0.020 ENSMUST00000101095.2
 Ctps2
cytidine 5'-triphosphate synthase 2
chr11_+_58199556 0.016 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
 Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr10_-_127751707 0.011 ENSMUST00000079692.5
 Gpr182
G protein-coupled receptor 182
chr1_+_17145357 0.010 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr10_+_120227030 0.007 ENSMUST00000020444.8
 Llph
LLP homolog, long-term synaptic facilitation (Aplysia)
chr12_-_4689926 0.003 ENSMUST00000080062.6
 Gm17541
predicted gene, 17541
chr2_-_175133322 0.000 ENSMUST00000099029.3
 Gm14399
predicted gene 14399

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 2.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.6 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.3 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 2.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 4.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 4.5 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.4 GO:0005536 glucose binding(GO:0005536)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 4.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol