Motif ID: Arid5b

Z-value: 0.217


Transcription factors associated with Arid5b:

Gene SymbolEntrez IDGene Name
Arid5b ENSMUSG00000019947.9 Arid5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_682787350.095.8e-01Click!


Activity profile for motif Arid5b.

activity profile for motif Arid5b


Sorted Z-values histogram for motif Arid5b

Sorted Z-values for motif Arid5b



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_109010955 0.707 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr9_+_21196705 0.598 ENSMUST00000003395.9
Pde4a
phosphodiesterase 4A, cAMP specific
chr10_-_6980376 0.577 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr18_+_62662108 0.465 ENSMUST00000163259.1
Gm17732
predicted gene, 17732
chr15_-_13173607 0.290 ENSMUST00000036439.4
Cdh6
cadherin 6
chr12_-_24680890 0.286 ENSMUST00000156453.2
Cys1
cystin 1
chr9_+_87022014 0.263 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr3_-_95882031 0.246 ENSMUST00000161994.1
Gm129
predicted gene 129
chr3_-_19264959 0.241 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr8_-_119840522 0.237 ENSMUST00000168698.1
ENSMUST00000034285.6
Cotl1

coactosin-like 1 (Dictyostelium)

chrX_-_157492280 0.215 ENSMUST00000112529.1
Sms
spermine synthase
chr9_-_45984816 0.198 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr6_+_97210689 0.196 ENSMUST00000044681.6
Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr7_-_67645195 0.195 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28

leucine rich repeat containing 28

chr9_+_112227443 0.194 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr12_-_10900296 0.185 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr15_-_44428303 0.173 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr16_+_32431225 0.159 ENSMUST00000115140.1
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr13_+_109685994 0.157 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr1_+_180568913 0.157 ENSMUST00000027777.6
Parp1
poly (ADP-ribose) polymerase family, member 1
chr13_+_21735055 0.151 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr3_-_95882193 0.151 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr8_-_79399513 0.145 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
Smad1


SMAD family member 1


chr12_-_91746020 0.142 ENSMUST00000166967.1
Ston2
stonin 2
chr10_+_94576254 0.137 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr5_-_31697598 0.136 ENSMUST00000031018.7
Rbks
ribokinase
chr4_+_132638987 0.134 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
Eya3




eyes absent 3 homolog (Drosophila)




chr1_+_163779575 0.125 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr9_-_106789130 0.125 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr12_+_110601439 0.124 ENSMUST00000018851.7
Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr10_+_116143881 0.123 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr4_-_129662442 0.119 ENSMUST00000003828.4
Kpna6
karyopherin (importin) alpha 6
chr18_+_23415400 0.098 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chrX_+_140456613 0.097 ENSMUST00000033809.3
Prps1
phosphoribosyl pyrophosphate synthetase 1
chr3_-_95882232 0.092 ENSMUST00000161866.1
Gm129
predicted gene 129
chr10_+_14523062 0.086 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr15_+_37233036 0.074 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2


grainyhead-like 2 (Drosophila)


chr3_-_89998656 0.070 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr5_+_115908644 0.068 ENSMUST00000141101.1
Cit
citron
chrX_-_101222426 0.068 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr10_+_127420867 0.066 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr9_+_122117338 0.064 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
Snrk


SNF related kinase


chrX_+_47912387 0.060 ENSMUST00000001202.8
ENSMUST00000115020.1
Ocrl

oculocerebrorenal syndrome of Lowe

chr4_-_75278246 0.060 ENSMUST00000030103.8
Tmem261
transmembrane protein 261
chr5_-_131538687 0.059 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr13_+_23533869 0.058 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr8_+_34115030 0.057 ENSMUST00000095345.3
Mboat4
membrane bound O-acyltransferase domain containing 4
chr7_-_101921186 0.056 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
Lrrc51


leucine rich repeat containing 51


chr2_-_84678828 0.053 ENSMUST00000111665.1
Tmx2
thioredoxin-related transmembrane protein 2
chr11_+_108682602 0.050 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr4_-_150909428 0.050 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
Park7


Parkinson disease (autosomal recessive, early onset) 7


chr14_-_52213379 0.047 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr11_-_110251736 0.040 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr2_-_151744142 0.038 ENSMUST00000109869.1
Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr3_+_95588990 0.033 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr1_+_88227005 0.032 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr2_+_84678396 0.029 ENSMUST00000102645.3
Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr15_-_55548164 0.025 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr2_-_84678051 0.025 ENSMUST00000053664.8
ENSMUST00000111664.1
Tmx2

thioredoxin-related transmembrane protein 2

chr4_+_105157339 0.024 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr16_-_32247152 0.021 ENSMUST00000042732.5
Fbxo45
F-box protein 45
chr11_-_109298090 0.021 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr5_+_31494736 0.015 ENSMUST00000076949.6
ENSMUST00000117700.1
Gpn1

GPN-loop GTPase 1

chr1_-_31222604 0.013 ENSMUST00000127775.1
4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr4_+_43631935 0.009 ENSMUST00000030191.8
Npr2
natriuretic peptide receptor 2
chr6_+_133105239 0.008 ENSMUST00000100864.4
2700089E24Rik
RIKEN cDNA 2700089E24 gene
chr6_+_120666388 0.004 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr14_-_47394253 0.002 ENSMUST00000177822.1
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr1_+_180330470 0.002 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) positive regulation of superoxide dismutase activity(GO:1901671) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of removal of superoxide radicals(GO:1904833) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0002177 manchette(GO:0002177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.0 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines