Motif ID: Arnt

Z-value: 0.477


Transcription factors associated with Arnt:

Gene SymbolEntrez IDGene Name
Arnt ENSMUSG00000015522.12 Arnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arntmm10_v2_chr3_+_95434386_95434428-0.609.4e-05Click!


Activity profile for motif Arnt.

activity profile for motif Arnt


Sorted Z-values histogram for motif Arnt

Sorted Z-values for motif Arnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_125490688 2.310 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr15_+_98167806 1.448 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr15_+_74721193 1.317 ENSMUST00000070923.1
Them6
thioesterase superfamily member 6
chr19_+_43440404 1.242 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr11_+_98937669 1.140 ENSMUST00000107475.2
ENSMUST00000068133.3
Rara

retinoic acid receptor, alpha

chr11_+_82388900 1.096 ENSMUST00000054245.4
ENSMUST00000092852.2
Tmem132e

transmembrane protein 132E

chr15_-_79834323 0.961 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr5_-_106458440 0.925 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr17_-_65613521 0.909 ENSMUST00000024897.8
Vapa
vesicle-associated membrane protein, associated protein A
chr8_-_45999860 0.868 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr19_+_41981709 0.857 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr13_-_38658991 0.827 ENSMUST00000001757.7
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr9_-_58202281 0.809 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_-_107458895 0.780 ENSMUST00000009617.8
Kcnc4
potassium voltage gated channel, Shaw-related subfamily, member 4
chr12_+_95692212 0.751 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr11_+_101316200 0.749 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr9_-_110654161 0.728 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr17_+_27556613 0.697 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr17_+_27556641 0.685 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1

high mobility group AT-hook 1

chr5_-_45639501 0.672 ENSMUST00000016023.7
Fam184b
family with sequence similarity 184, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 2.0 GO:0006284 base-excision repair(GO:0006284)
0.1 1.7 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.4 1.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 1.0 GO:0009649 entrainment of circadian clock(GO:0009649)
0.2 0.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.8 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.8 GO:0001709 cell fate determination(GO:0001709)
0.2 0.7 GO:0070889 platelet alpha granule organization(GO:0070889)
0.2 0.7 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 0.6 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 2.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.8 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 2.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 1.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2 1.0 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.6 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)

Gene overrepresentation in C2:CP category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 1.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.2 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 2.0 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.8 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.4 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.0 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand