Motif ID: Atf1_Creb5
Z-value: 0.471
Transcription factors associated with Atf1_Creb5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atf1 | ENSMUSG00000023027.6 | Atf1 |
Creb5 | ENSMUSG00000053007.6 | Creb5 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Atf1 | mm10_v2_chr15_+_100227819_100227856 | 0.62 | 3.6e-05 | Click! |
Creb5 | mm10_v2_chr6_+_53573364_53573394 | 0.46 | 4.1e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.6 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
0.7 | 2.2 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.5 | 2.8 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
0.4 | 4.2 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.4 | 1.1 | GO:1901079 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) |
0.4 | 1.4 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
0.3 | 2.4 | GO:0098535 | positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535) |
0.3 | 0.9 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.3 | 1.0 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
0.2 | 0.7 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.2 | 3.2 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.2 | 1.0 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.2 | 0.6 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.2 | 1.7 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.2 | 1.6 | GO:0030432 | peristalsis(GO:0030432) |
0.2 | 1.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.1 | 1.3 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
0.1 | 0.4 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
0.1 | 0.6 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
0.1 | 0.7 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.1 | 0.5 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.1 | 0.5 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
0.1 | 1.2 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.1 | 0.7 | GO:0051189 | molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.1 | 0.5 | GO:1903753 | negative regulation of p38MAPK cascade(GO:1903753) |
0.1 | 0.3 | GO:1900864 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
0.1 | 1.1 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.1 | 2.0 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.1 | 0.6 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.1 | 0.3 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.1 | 0.6 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.1 | 1.4 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
0.1 | 0.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 1.1 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.1 | 0.3 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
0.1 | 0.4 | GO:0070269 | pyroptosis(GO:0070269) |
0.1 | 0.7 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.3 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.1 | 0.4 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.1 | 0.6 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
0.1 | 0.3 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.1 | 0.3 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.1 | 0.8 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.1 | 0.2 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
0.1 | 0.3 | GO:1903236 | regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) |
0.1 | 0.2 | GO:1902527 | regulation of protein monoubiquitination(GO:1902525) positive regulation of protein monoubiquitination(GO:1902527) |
0.1 | 0.5 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.1 | 0.4 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
0.1 | 0.8 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.4 | GO:0032196 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196) |
0.1 | 0.4 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.1 | 0.6 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
0.1 | 0.2 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.1 | 1.9 | GO:0034508 | centromere complex assembly(GO:0034508) |
0.1 | 0.8 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.1 | 0.6 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.1 | 0.2 | GO:0035973 | aggrephagy(GO:0035973) |
0.1 | 0.9 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 0.3 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
0.1 | 0.5 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
0.1 | 0.2 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
0.1 | 0.2 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.1 | 0.2 | GO:2000319 | negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
0.0 | 0.5 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.0 | 0.1 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) |
0.0 | 0.5 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
0.0 | 0.3 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.0 | 0.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.0 | 0.2 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
0.0 | 0.1 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
0.0 | 0.4 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.0 | 0.1 | GO:0070649 | polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649) |
0.0 | 0.7 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.0 | 0.1 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
0.0 | 1.5 | GO:0009409 | response to cold(GO:0009409) |
0.0 | 0.4 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.0 | 0.2 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.0 | 0.1 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.0 | 1.1 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.0 | 0.2 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.1 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.0 | 0.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.0 | 0.2 | GO:0021764 | amygdala development(GO:0021764) |
0.0 | 0.7 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
0.0 | 0.5 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
0.0 | 0.0 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
0.0 | 0.2 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.0 | 0.4 | GO:0019985 | translesion synthesis(GO:0019985) |
0.0 | 0.3 | GO:0070475 | rRNA base methylation(GO:0070475) |
0.0 | 0.2 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.0 | 1.0 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.0 | 0.1 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.0 | 0.1 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.0 | 1.0 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.2 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.0 | 0.3 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.0 | 0.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
0.0 | 0.1 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
0.0 | 0.5 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.4 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.0 | 0.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.0 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
0.0 | 0.0 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
0.0 | 0.3 | GO:0060253 | negative regulation of glial cell proliferation(GO:0060253) |
0.0 | 0.5 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 0.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
0.0 | 0.1 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
0.0 | 0.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.4 | GO:0048266 | behavioral response to pain(GO:0048266) |
0.0 | 0.4 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.0 | 0.1 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
0.0 | 1.0 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 0.2 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) angiotensin-activated signaling pathway(GO:0038166) |
0.0 | 0.1 | GO:1902741 | type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
0.0 | 0.3 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.1 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.0 | 0.2 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
0.0 | 0.1 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.0 | 0.1 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.0 | 1.0 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.2 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
0.0 | 0.1 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.1 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
0.0 | 0.2 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
0.0 | 0.2 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.4 | GO:0046777 | protein autophosphorylation(GO:0046777) |
0.0 | 0.1 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.0 | 0.1 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.0 | 0.1 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 0.7 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.2 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.0 | 0.2 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
0.0 | 0.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.0 | 0.1 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.0 | 0.0 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
0.0 | 0.0 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.0 | 0.1 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.2 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
0.4 | 2.4 | GO:0098536 | deuterosome(GO:0098536) |
0.4 | 5.2 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
0.3 | 2.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.3 | 2.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.2 | 1.1 | GO:0042583 | chromaffin granule(GO:0042583) |
0.1 | 1.0 | GO:0001940 | male pronucleus(GO:0001940) |
0.1 | 1.1 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 1.0 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.4 | GO:0061702 | inflammasome complex(GO:0061702) |
0.1 | 0.7 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 0.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.1 | 0.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.1 | 0.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 0.2 | GO:0097447 | dendritic tree(GO:0097447) |
0.1 | 0.7 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.0 | 1.4 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 0.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.3 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.0 | 0.7 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 1.0 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.3 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:1990037 | Lewy body core(GO:1990037) |
0.0 | 1.2 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 0.1 | GO:0098842 | postsynaptic early endosome(GO:0098842) |
0.0 | 0.1 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.0 | 0.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.0 | 0.2 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.0 | 0.6 | GO:0000242 | pericentriolar material(GO:0000242) |
0.0 | 1.8 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 1.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.5 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.3 | GO:0000800 | lateral element(GO:0000800) |
0.0 | 0.6 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.1 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.0 | 0.2 | GO:0016589 | NURF complex(GO:0016589) |
0.0 | 1.4 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 5.7 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.8 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 2.8 | GO:0005769 | early endosome(GO:0005769) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.8 | GO:0043515 | kinetochore binding(GO:0043515) |
0.5 | 1.6 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.3 | 4.6 | GO:0003680 | AT DNA binding(GO:0003680) |
0.2 | 0.7 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.2 | 0.9 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
0.2 | 4.2 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.2 | 1.4 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.1 | 0.4 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
0.1 | 0.4 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
0.1 | 1.9 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 1.0 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.1 | 0.4 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.1 | 0.8 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 2.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.1 | 1.2 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.1 | 0.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.1 | 0.9 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.1 | 0.3 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 0.3 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.1 | 0.3 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
0.1 | 0.3 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.1 | 0.8 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.1 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 0.3 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.1 | 0.5 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.1 | 0.2 | GO:0004458 | D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898) |
0.1 | 0.2 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.0 | 0.7 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 0.1 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
0.0 | 0.3 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 1.2 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.2 | GO:0045545 | syndecan binding(GO:0045545) |
0.0 | 0.1 | GO:0016015 | morphogen activity(GO:0016015) |
0.0 | 0.2 | GO:0042731 | PH domain binding(GO:0042731) |
0.0 | 0.4 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.5 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.0 | 0.5 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 0.2 | GO:0032027 | myosin light chain binding(GO:0032027) |
0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 1.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.1 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
0.0 | 0.1 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.0 | 1.1 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.1 | GO:0009041 | uridylate kinase activity(GO:0009041) |
0.0 | 0.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.1 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
0.0 | 0.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.0 | 0.1 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
0.0 | 0.1 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
0.0 | 0.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 1.0 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.1 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
0.0 | 0.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.8 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 4.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.2 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.1 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.0 | 0.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.1 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.0 | 0.1 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.0 | 0.1 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.0 | 0.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.0 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
0.0 | 1.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.1 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.0 | 0.2 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.2 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.3 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 1.0 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
0.0 | 0.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 0.1 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 1.4 | GO:0047485 | protein N-terminus binding(GO:0047485) |
0.0 | 0.1 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.2 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 3.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.1 | 0.6 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 1.8 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 4.6 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.3 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.0 | 0.2 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 0.7 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 0.6 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.7 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.0 | 2.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 0.1 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.4 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 4.6 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.2 | 2.2 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.2 | 1.1 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.1 | 4.2 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.1 | 2.5 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 0.8 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 1.0 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.0 | 0.7 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 2.4 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 0.4 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.0 | 0.5 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.0 | 0.3 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 0.1 | REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
0.0 | 0.4 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
0.0 | 2.0 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 1.1 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 1.0 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.7 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 0.4 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
0.0 | 0.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 1.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.5 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 0.9 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.2 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 1.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.7 | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
0.0 | 0.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.1 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.0 | 0.2 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.2 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 0.5 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.3 | REACTOME_RNA_POL_I_TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |