Motif ID: Atf1_Creb5
Z-value: 0.471
Transcription factors associated with Atf1_Creb5:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Atf1 | ENSMUSG00000023027.6 | Atf1 |
| Creb5 | ENSMUSG00000053007.6 | Creb5 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Atf1 | mm10_v2_chr15_+_100227819_100227856 | 0.62 | 3.6e-05 | Click! |
| Creb5 | mm10_v2_chr6_+_53573364_53573394 | 0.46 | 4.1e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 140 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.6 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
| 0.4 | 4.2 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
| 0.2 | 3.2 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.5 | 2.8 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.3 | 2.4 | GO:0098535 | positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535) |
| 0.7 | 2.2 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 2.0 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.1 | 1.9 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.2 | 1.7 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.2 | 1.6 | GO:0030432 | peristalsis(GO:0030432) |
| 0.0 | 1.5 | GO:0009409 | response to cold(GO:0009409) |
| 0.4 | 1.4 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
| 0.1 | 1.4 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.1 | 1.3 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.1 | 1.2 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.4 | 1.1 | GO:1901079 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) |
| 0.2 | 1.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.1 | 1.1 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.1 | 1.1 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
| 0.0 | 1.1 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 50 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.4 | 5.2 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 1.1 | 4.2 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.0 | 2.8 | GO:0005769 | early endosome(GO:0005769) |
| 0.4 | 2.4 | GO:0098536 | deuterosome(GO:0098536) |
| 0.3 | 2.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.3 | 2.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 1.8 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 1.4 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 1.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.2 | GO:0097546 | ciliary base(GO:0097546) |
| 0.2 | 1.1 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.1 | 1.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 1.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 1.0 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.1 | 1.0 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 1.0 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.8 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 0.7 | GO:0033503 | HULC complex(GO:0033503) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 92 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.6 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 4.2 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.0 | 4.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.6 | 2.8 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 2.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 1.9 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.5 | 1.6 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.2 | 1.4 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.0 | 1.4 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 1.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 1.2 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.0 | 1.2 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 1.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 1.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 1.0 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.0 | 1.0 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 1.0 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.2 | 0.9 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.1 | 0.9 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.1 | 0.8 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
Gene overrepresentation in C2:CP category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.1 | 3.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 2.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.8 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.1 | 1.2 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.7 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
| 0.0 | 0.7 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
| 0.1 | 0.6 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.6 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.0 | 0.5 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.4 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 0.3 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 0.2 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.0 | 0.1 | PID_IL5_PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 32 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.6 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.1 | 4.2 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 2.5 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 2.4 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.2 | 2.2 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 2.0 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 1.1 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 1.1 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 1.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.0 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 1.0 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.9 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 0.8 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.7 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.7 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.7 | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.0 | 0.5 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
| 0.0 | 0.5 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.5 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
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