Motif ID: Atf6

Z-value: 0.886


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_170867784-0.241.5e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_23988852 10.034 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr5_-_89883321 6.179 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr12_+_82616885 6.166 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr16_+_41532999 5.072 ENSMUST00000099761.3
Lsamp
limbic system-associated membrane protein
chr6_-_136173492 5.013 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr8_+_125995102 4.938 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr4_+_125490688 4.745 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr3_+_123267445 4.319 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr6_-_126740151 4.053 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr5_+_134986191 3.888 ENSMUST00000094245.2
Cldn3
claudin 3
chr6_+_77242644 3.670 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 3.611 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr13_+_58807884 3.486 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chrY_-_1245685 3.437 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chrX_+_41401128 3.326 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_+_41532851 3.242 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr11_-_108343917 2.963 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr5_+_137288273 2.810 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr13_+_118714678 2.728 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr3_+_104638658 2.726 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr15_-_77956658 2.610 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr13_-_92131494 2.575 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr13_-_105054895 2.508 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr8_-_70487314 2.460 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr4_+_128058962 2.312 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr9_-_95750335 2.220 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr5_+_35056813 2.181 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
Dok7


docking protein 7


chr5_-_136170634 2.098 ENSMUST00000041048.1
Orai2
ORAI calcium release-activated calcium modulator 2
chr13_+_93303757 2.068 ENSMUST00000109494.1
Homer1
homer homolog 1 (Drosophila)
chr17_+_46297917 2.042 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr6_-_8778439 2.034 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1


chr18_-_31447383 2.030 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr3_+_138065052 2.023 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chrY_-_1245753 2.002 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr16_+_17759601 1.995 ENSMUST00000129199.1
ENSMUST00000165790.1
Klhl22

kelch-like 22

chr15_-_81960851 1.992 ENSMUST00000071462.6
ENSMUST00000023112.5
Pmm1

phosphomannomutase 1

chr5_+_37185897 1.971 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr12_-_4841583 1.961 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr19_+_4099998 1.953 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr3_+_101377074 1.940 ENSMUST00000043983.5
Igsf3
immunoglobulin superfamily, member 3
chr8_-_70439557 1.933 ENSMUST00000076615.5
Crtc1
CREB regulated transcription coactivator 1
chr2_+_155276297 1.910 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr6_-_8778106 1.868 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr9_-_51008936 1.756 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr1_+_50927511 1.738 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr16_+_17759630 1.717 ENSMUST00000140306.1
ENSMUST00000117192.1
Klhl22

kelch-like 22

chr1_-_136260873 1.696 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chrX_+_153139941 1.691 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr5_+_35057059 1.639 ENSMUST00000050709.3
Dok7
docking protein 7
chr4_+_155734800 1.628 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr13_-_59557230 1.592 ENSMUST00000165370.1
ENSMUST00000109830.2
ENSMUST00000022040.6
ENSMUST00000171606.1
ENSMUST00000167096.1
ENSMUST00000166585.1
Agtpbp1





ATP/GTP binding protein 1





chr15_-_98881255 1.557 ENSMUST00000024518.9
Rhebl1
Ras homolog enriched in brain like 1
chr14_-_124677089 1.549 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr6_-_101377897 1.536 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr8_+_114205590 1.504 ENSMUST00000049509.6
ENSMUST00000150963.1
Vat1l

vesicle amine transport protein 1 homolog-like (T. californica)

chr18_+_23803962 1.501 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_-_52471534 1.495 ENSMUST00000059428.5
Ccdc149
coiled-coil domain containing 149
chr9_+_120492606 1.474 ENSMUST00000007139.4
Eif1b
eukaryotic translation initiation factor 1B
chr17_-_24205514 1.471 ENSMUST00000097376.3
ENSMUST00000168410.2
ENSMUST00000167791.2
ENSMUST00000040474.7
Tbc1d24



TBC1 domain family, member 24



chr2_+_67748212 1.424 ENSMUST00000180887.1
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr17_-_37023349 1.411 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr8_+_25720054 1.394 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr5_-_118244861 1.391 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chrX_+_73787002 1.388 ENSMUST00000166518.1
Ssr4
signal sequence receptor, delta
chr5_-_135251209 1.373 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr19_+_11965817 1.361 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chrX_+_73787062 1.358 ENSMUST00000002090.2
Ssr4
signal sequence receptor, delta
chr1_+_99772765 1.355 ENSMUST00000086738.3
Cntnap5b
contactin associated protein-like 5B
chr12_-_36042476 1.353 ENSMUST00000020896.8
Tspan13
tetraspanin 13
chr4_-_149774238 1.337 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr16_-_4880284 1.336 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr12_-_72070991 1.331 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr13_+_5861489 1.314 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr3_-_127225847 1.302 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr6_-_124464772 1.300 ENSMUST00000008297.4
Clstn3
calsyntenin 3
chr2_+_55437100 1.290 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr3_-_127225917 1.283 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr13_-_93499803 1.266 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr10_+_29211637 1.253 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr5_-_24447587 1.246 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr14_+_34819811 1.245 ENSMUST00000043349.5
Grid1
glutamate receptor, ionotropic, delta 1
chr4_-_142239356 1.237 ENSMUST00000036476.3
Kazn
kazrin, periplakin interacting protein
chr13_+_93304066 1.214 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr5_+_137030275 1.181 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr10_-_18743691 1.165 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chrX_-_85776606 1.160 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
Gyk


glycerol kinase


chr3_+_103575275 1.136 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chrX_-_134751331 1.121 ENSMUST00000113194.1
ENSMUST00000052431.5
Armcx6

armadillo repeat containing, X-linked 6

chrX_-_7375830 1.116 ENSMUST00000115744.1
Usp27x
ubiquitin specific peptidase 27, X chromosome
chr5_-_65492984 1.105 ENSMUST00000139122.1
Smim14
small integral membrane protein 14
chr11_-_74590065 1.093 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr19_+_8617991 1.072 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr17_-_6477102 1.058 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr3_+_103575231 1.032 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr17_+_6270475 1.027 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr7_-_126898249 1.020 ENSMUST00000121532.1
ENSMUST00000032926.5
Tmem219

transmembrane protein 219

chr7_+_45785331 1.006 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr7_-_140049083 0.995 ENSMUST00000055353.7
Msx3
msh homeobox 3
chr1_+_143640664 0.994 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_-_140049140 0.976 ENSMUST00000172775.2
Msx3
msh homeobox 3
chr7_+_47050628 0.968 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr13_+_46669517 0.957 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr5_-_135934590 0.949 ENSMUST00000055808.5
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr13_-_38528412 0.942 ENSMUST00000035988.8
Txndc5
thioredoxin domain containing 5
chr5_+_144100387 0.941 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr6_-_131293187 0.927 ENSMUST00000032307.5
Magohb
mago-nashi homolog B (Drosophila)
chrX_-_73786888 0.922 ENSMUST00000052761.8
Idh3g
isocitrate dehydrogenase 3 (NAD+), gamma
chr9_-_86695897 0.920 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr6_+_48537560 0.903 ENSMUST00000040361.5
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr7_+_16098458 0.898 ENSMUST00000006181.6
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr15_+_77084367 0.887 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr18_+_62977854 0.886 ENSMUST00000150267.1
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr10_-_127666598 0.866 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr11_-_69921057 0.859 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr4_+_46489248 0.856 ENSMUST00000030018.4
Nans
N-acetylneuraminic acid synthase (sialic acid synthase)
chr7_-_45742455 0.847 ENSMUST00000107735.3
ENSMUST00000140127.1
Sult2b1

sulfotransferase family, cytosolic, 2B, member 1

chr11_+_16257706 0.835 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr7_+_126950518 0.829 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr4_+_43406435 0.827 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr11_-_30025915 0.822 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr9_-_103761820 0.815 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr4_+_88094599 0.800 ENSMUST00000097992.3
Focad
focadhesin
chr9_+_121760000 0.797 ENSMUST00000093772.3
Zfp651
zinc finger protein 651
chr17_+_45563928 0.790 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chr11_-_69920581 0.774 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr16_-_57231434 0.771 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chrX_+_136666375 0.764 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
Tceal3


transcription elongation factor A (SII)-like 3


chr9_-_32541589 0.756 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr10_-_127666673 0.748 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr2_-_71546745 0.746 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr5_-_137533170 0.739 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr8_+_107056870 0.738 ENSMUST00000034392.5
ENSMUST00000170962.1
Nip7

nuclear import 7 homolog (S. cerevisiae)

chr5_-_122989086 0.729 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr17_+_37050631 0.720 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr5_-_137533212 0.719 ENSMUST00000111038.1
ENSMUST00000143495.1
Epo
Gnb2
erythropoietin
guanine nucleotide binding protein (G protein), beta 2
chr18_+_62977826 0.699 ENSMUST00000025474.6
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr3_+_107595031 0.698 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr4_-_70534904 0.693 ENSMUST00000107359.2
Megf9
multiple EGF-like-domains 9
chr7_-_100863373 0.687 ENSMUST00000142885.1
ENSMUST00000008462.3
Relt

RELT tumor necrosis factor receptor

chr19_+_10895225 0.685 ENSMUST00000025642.7
Prpf19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr2_+_18672384 0.684 ENSMUST00000171845.1
ENSMUST00000061158.4
Commd3

COMM domain containing 3

chr13_-_37994111 0.661 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr13_+_73467197 0.661 ENSMUST00000022099.8
Lpcat1
lysophosphatidylcholine acyltransferase 1
chr19_+_8741669 0.656 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
Stx5a


syntaxin 5A


chr10_-_81291227 0.642 ENSMUST00000045744.6
Tjp3
tight junction protein 3
chr17_+_87107621 0.636 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr6_+_17693965 0.636 ENSMUST00000115419.1
St7
suppression of tumorigenicity 7
chr7_+_126950687 0.635 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr19_+_3851797 0.622 ENSMUST00000072055.6
Chka
choline kinase alpha
chr17_-_80290476 0.621 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr11_-_69920892 0.621 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr6_-_119848093 0.605 ENSMUST00000079582.4
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr8_+_4493443 0.604 ENSMUST00000175781.2
Cers4
ceramide synthase 4
chr5_-_137533297 0.603 ENSMUST00000111020.1
ENSMUST00000111023.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr7_-_126082406 0.595 ENSMUST00000073935.5
Gsg1l
GSG1-like
chr7_+_126950837 0.592 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr13_-_100730839 0.589 ENSMUST00000091299.6
Cdk7
cyclin-dependent kinase 7
chr16_-_36874806 0.585 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chr7_-_25250720 0.583 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr5_-_8367982 0.574 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr3_-_94786469 0.570 ENSMUST00000107273.1
Cgn
cingulin
chr9_-_78109020 0.567 ENSMUST00000001402.7
Fbxo9
f-box protein 9
chr19_+_3851972 0.561 ENSMUST00000025760.6
Chka
choline kinase alpha
chr11_-_96916407 0.555 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr3_-_127162328 0.552 ENSMUST00000182994.1
Ank2
ankyrin 2, brain
chr6_+_17693905 0.548 ENSMUST00000115420.1
St7
suppression of tumorigenicity 7
chr19_-_3575708 0.540 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr16_-_16829276 0.532 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr6_-_124857707 0.532 ENSMUST00000023958.3
Leprel2
leprecan-like 2
chr7_+_141061274 0.529 ENSMUST00000048002.5
B4galnt4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr11_-_96916366 0.525 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr4_-_121017201 0.522 ENSMUST00000043200.7
Smap2
small ArfGAP 2
chr3_-_144205165 0.520 ENSMUST00000120539.1
Lmo4
LIM domain only 4
chr1_+_24678536 0.520 ENSMUST00000095062.3
Lmbrd1
LMBR1 domain containing 1
chr5_+_31698050 0.520 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
Bre



brain and reproductive organ-expressed protein



chr2_+_156721037 0.519 ENSMUST00000109566.2
ENSMUST00000146412.2
ENSMUST00000177013.1
ENSMUST00000171030.2
Dlgap4



discs, large homolog-associated protein 4 (Drosophila)



chr1_-_180245757 0.512 ENSMUST00000111104.1
Psen2
presenilin 2
chr6_+_17694005 0.511 ENSMUST00000081635.6
ENSMUST00000052113.5
St7

suppression of tumorigenicity 7

chr4_+_59003121 0.510 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr8_-_36732897 0.501 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr6_-_30693676 0.500 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr7_+_132931142 0.498 ENSMUST00000106157.1
Zranb1
zinc finger, RAN-binding domain containing 1
chr1_-_17097839 0.489 ENSMUST00000038382.4
Jph1
junctophilin 1
chr8_-_11550689 0.489 ENSMUST00000049461.5
Cars2
cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
chrX_-_74373260 0.488 ENSMUST00000073067.4
ENSMUST00000037967.5
Slc10a3

solute carrier family 10 (sodium/bile acid cotransporter family), member 3

chr3_-_94786430 0.488 ENSMUST00000107272.1
Cgn
cingulin
chr13_+_13784278 0.488 ENSMUST00000021734.7
Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr11_+_70023905 0.484 ENSMUST00000124568.2
Dlg4
discs, large homolog 4 (Drosophila)
chr16_+_33062512 0.483 ENSMUST00000023497.2
Lmln
leishmanolysin-like (metallopeptidase M8 family)
chr11_-_96916448 0.482 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr5_+_31697960 0.480 ENSMUST00000114515.2
Bre
brain and reproductive organ-expressed protein
chr2_-_91070283 0.473 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr6_-_118479237 0.472 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr9_+_119444923 0.468 ENSMUST00000035094.6
ENSMUST00000164213.2
Exog

endo/exonuclease (5'-3'), endonuclease G-like

chrX_+_101299143 0.465 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr19_+_8741413 0.464 ENSMUST00000176381.1
Stx5a
syntaxin 5A
chr8_+_105701624 0.464 ENSMUST00000093195.6
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr8_-_105255100 0.464 ENSMUST00000093217.2
ENSMUST00000161745.2
ENSMUST00000136822.2
B3gnt9


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9


chr2_+_156721069 0.461 ENSMUST00000000094.7
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr6_-_119848059 0.460 ENSMUST00000184864.1
Erc1
ELKS/RAB6-interacting/CAST family member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.3 5.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.2 6.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.2 3.6 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
1.0 3.0 GO:0002159 desmosome assembly(GO:0002159)
0.8 5.0 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.7 2.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.7 4.0 GO:0019695 choline metabolic process(GO:0019695)
0.7 2.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.6 1.9 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.6 3.5 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.5 4.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.5 8.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5 3.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5 1.4 GO:1990523 bone regeneration(GO:1990523)
0.4 1.7 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.4 0.8 GO:0097106 postsynaptic density organization(GO:0097106)
0.4 1.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 1.1 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.4 1.1 GO:0015747 urate transport(GO:0015747)
0.3 3.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 16.1 GO:0035640 exploration behavior(GO:0035640)
0.3 1.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.3 2.0 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.3 1.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.3 1.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 0.9 GO:2000331 regulation of terminal button organization(GO:2000331)
0.3 2.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 2.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 3.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 2.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 0.3 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 0.7 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.7 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 1.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 1.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.9 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 1.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.9 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 1.6 GO:0090166 Golgi disassembly(GO:0090166)
0.2 1.0 GO:0009405 pathogenesis(GO:0009405)
0.2 1.7 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.5 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.2 0.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 1.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 4.2 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.2 0.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 2.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 2.8 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.4 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 1.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.2 GO:0031424 keratinization(GO:0031424)
0.1 0.7 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:2001013 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.6 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.7 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 2.2 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.4 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 0.9 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.8 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.2 GO:0043084 penile erection(GO:0043084)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 2.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.1 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.5 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 1.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 4.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 4.7 GO:0001881 receptor recycling(GO:0001881)
0.1 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.1 1.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 2.1 GO:0060074 synapse maturation(GO:0060074)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 2.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) dibasic protein processing(GO:0090472)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.4 GO:0021886 female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.1 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 1.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.7 GO:0008272 sulfate transport(GO:0008272)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 2.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.5 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.8 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 4.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.5 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.5 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.7 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 1.8 GO:0031929 TOR signaling(GO:0031929)
0.0 0.6 GO:0001893 maternal placenta development(GO:0001893)
0.0 1.0 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 8.3 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.8 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.9 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.0 GO:1901678 iron coordination entity transport(GO:1901678)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.7 11.1 GO:0043083 synaptic cleft(GO:0043083)
0.5 3.7 GO:0005827 polar microtubule(GO:0005827)
0.3 1.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 3.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 1.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 1.2 GO:0001533 cornified envelope(GO:0001533)
0.2 3.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 8.6 GO:0043034 costamere(GO:0043034)
0.2 8.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 2.0 GO:0097449 astrocyte projection(GO:0097449)
0.1 2.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.9 GO:0044754 autolysosome(GO:0044754)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 9.8 GO:0005657 replication fork(GO:0005657)
0.1 0.2 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 2.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 5.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 4.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.4 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 3.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.0 GO:0036477 somatodendritic compartment(GO:0036477)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.0 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 11.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 3.2 GO:0009986 cell surface(GO:0009986)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 2.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0005901 caveola(GO:0005901)
0.0 0.5 GO:0097060 synaptic membrane(GO:0097060)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
1.0 3.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.9 4.7 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.8 10.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.7 3.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.7 2.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.7 3.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 5.0 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.6 2.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.6 4.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.6 2.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 2.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 5.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 2.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 4.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 0.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 0.9 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 3.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 1.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 0.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.3 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.7 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 4.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 2.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 3.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.4 GO:0036435 deubiquitinase activator activity(GO:0035800) K48-linked polyubiquitin binding(GO:0036435)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.8 GO:1990239 steroid hormone binding(GO:1990239)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 4.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.2 GO:1903135 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) cupric ion binding(GO:1903135)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 8.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 1.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) neuroligin family protein binding(GO:0097109)
0.1 3.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.7 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0071074 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 2.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 2.6 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 6.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 5.8 GO:0004175 endopeptidase activity(GO:0004175)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 1.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.9 PID_FOXO_PATHWAY FoxO family signaling
0.1 1.9 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 4.5 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 2.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 4.0 PID_SHP2_PATHWAY SHP2 signaling
0.1 1.5 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 6.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 2.1 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.7 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.2 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.6 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.6 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 3.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 2.6 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 8.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 2.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.7 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 4.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 1.1 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 2.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.2 1.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 4.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 4.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 6.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 4.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 0.8 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.6 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.1 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 5.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 2.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 3.3 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.4 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling