Motif ID: Barhl1

Z-value: 0.332


Transcription factors associated with Barhl1:

Gene SymbolEntrez IDGene Name
Barhl1 ENSMUSG00000026805.8 Barhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl1mm10_v2_chr2_-_28916668_28916668-0.463.8e-03Click!


Activity profile for motif Barhl1.

activity profile for motif Barhl1


Sorted Z-values histogram for motif Barhl1

Sorted Z-values for motif Barhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_92292380 1.219 ENSMUST00000047383.3
 Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr5_+_149678224 1.185 ENSMUST00000100404.3
 B3galtl
beta 1,3-galactosyltransferase-like
chr5_-_62766153 1.130 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr16_+_10827921 1.070 ENSMUST00000181732.1
 Gm26822
predicted gene, 26822
chr15_-_43869993 0.733 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr18_-_32559914 0.648 ENSMUST00000174000.1
ENSMUST00000174459.1
 Gypc

glycophorin C

chr11_+_102430315 0.526 ENSMUST00000049460.4
ENSMUST00000129997.1
 Grn

granulin

chr3_-_146770603 0.488 ENSMUST00000106138.1
 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr3_+_116008220 0.458 ENSMUST00000106502.1
 Extl2
exostoses (multiple)-like 2
chr3_-_146770218 0.428 ENSMUST00000106137.1
 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_+_63014934 0.361 ENSMUST00000091560.4
 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr15_+_25752860 0.335 ENSMUST00000022882.5
ENSMUST00000135173.1
 Myo10

myosin X

chr6_+_125349699 0.329 ENSMUST00000032491.8
 Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr6_+_72097561 0.328 ENSMUST00000069994.4
ENSMUST00000114112.1
 St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr15_+_55112317 0.312 ENSMUST00000096433.3
 Deptor
DEP domain containing MTOR-interacting protein
chr13_+_63015167 0.300 ENSMUST00000021911.8
 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr17_-_78418083 0.290 ENSMUST00000070039.7
ENSMUST00000112487.1
 Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr17_+_55892184 0.288 ENSMUST00000054780.8
 Zfp959
zinc finger protein 959
chr18_+_37355271 0.285 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr2_+_83812567 0.283 ENSMUST00000051454.3
 Fam171b
family with sequence similarity 171, member B
chr17_-_25115905 0.278 ENSMUST00000024987.5
ENSMUST00000115181.2
 Telo2

TEL2, telomere maintenance 2, homolog (S. cerevisiae)

chr11_+_78826575 0.247 ENSMUST00000147875.2
ENSMUST00000141321.1
 Lyrm9

LYR motif containing 9

chr6_-_41636389 0.235 ENSMUST00000031902.5
 Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr7_+_127800604 0.214 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr13_-_35027077 0.213 ENSMUST00000170538.1
ENSMUST00000163280.1
 Eci2

enoyl-Coenzyme A delta isomerase 2

chr1_+_115684727 0.211 ENSMUST00000043725.7
 Cntnap5a
contactin associated protein-like 5A
chr14_+_25980039 0.201 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr11_+_22971991 0.182 ENSMUST00000049506.5
 Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr16_+_44867097 0.159 ENSMUST00000102805.3
 Cd200r2
Cd200 receptor 2
chr6_-_59426279 0.152 ENSMUST00000051065.4
 Gprin3
GPRIN family member 3
chr7_+_45896941 0.138 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr11_+_116198853 0.105 ENSMUST00000021130.6
 Ten1
TEN1 telomerase capping complex subunit
chrX_+_112604274 0.103 ENSMUST00000071814.6
 Zfp711
zinc finger protein 711
chr16_-_32868325 0.100 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
 1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr16_+_33251415 0.099 ENSMUST00000023502.4
 Snx4
sorting nexin 4
chr7_+_12834743 0.091 ENSMUST00000004614.8
 Zfp110
zinc finger protein 110
chr2_-_45110336 0.084 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chr7_+_45897429 0.080 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chr5_-_23783700 0.079 ENSMUST00000119946.1
 Pus7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr18_+_12972225 0.075 ENSMUST00000025290.5
 Impact
imprinted and ancient
chr5_-_62765618 0.075 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_117156144 0.061 ENSMUST00000102696.4
 Rps8
ribosomal protein S8
chr16_-_91618986 0.061 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
 Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr5_-_87482258 0.046 ENSMUST00000079811.6
ENSMUST00000144144.1
 Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr5_+_34915915 0.039 ENSMUST00000050535.1
 Msantd1
Myb/SANT-like DNA-binding domain containing 1
chr17_+_45734506 0.033 ENSMUST00000180558.1
 F630040K05Rik
RIKEN cDNA F630040K05 gene
chr10_-_127030789 0.030 ENSMUST00000120547.1
ENSMUST00000152054.1
 Tsfm

Ts translation elongation factor, mitochondrial

chr3_-_130709419 0.023 ENSMUST00000043937.7
 Ostc
oligosaccharyltransferase complex subunit
chr9_+_36832684 0.011 ENSMUST00000034630.8
 Fez1
fasciculation and elongation protein zeta 1 (zygin I)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.5 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.2 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.1 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 0.5 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.9 PID_IL3_PATHWAY IL3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis