Motif ID: Barhl2

Z-value: 0.394


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_106458470-0.391.8e-02Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_101377897 2.028 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr12_-_34528844 1.846 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr3_-_80802789 1.567 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr5_-_110839575 1.411 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr1_+_165788681 1.267 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr1_+_165788746 1.037 ENSMUST00000161559.2
Cd247
CD247 antigen
chr3_-_49757257 1.025 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr17_-_49564262 1.013 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr16_-_22439719 0.994 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr5_-_110839757 0.928 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr6_+_125552948 0.923 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr5_+_110839973 0.907 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr1_-_163725123 0.902 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr18_-_78206408 0.854 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr14_+_30825580 0.849 ENSMUST00000006701.5
Tmem110
transmembrane protein 110
chrX_+_71663665 0.842 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr11_+_85832551 0.756 ENSMUST00000000095.6
Tbx2
T-box 2
chr14_-_88471396 0.706 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr17_+_35439155 0.700 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr18_+_61045139 0.698 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr2_+_59612034 0.696 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr7_+_127841817 0.625 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr12_+_78748947 0.623 ENSMUST00000082024.5
Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr5_-_37824580 0.607 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr7_+_127841752 0.599 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chrX_+_82948861 0.513 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr19_+_8617991 0.444 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chrX_+_169879596 0.434 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr11_+_112782182 0.423 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr2_+_181319714 0.422 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr18_+_61639542 0.403 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr16_-_22439570 0.403 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr2_+_181319806 0.378 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr11_-_20332689 0.377 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_-_20332654 0.376 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_+_35220834 0.365 ENSMUST00000118793.1
Gm16181
predicted gene 16181
chr14_+_21500879 0.364 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr18_-_80986578 0.352 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr4_+_154960915 0.346 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr9_-_13827029 0.340 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr19_-_6969746 0.339 ENSMUST00000025912.8
Plcb3
phospholipase C, beta 3
chr7_+_101969796 0.336 ENSMUST00000084852.5
Numa1
nuclear mitotic apparatus protein 1
chr7_+_25301343 0.334 ENSMUST00000080288.3
Prr19
proline rich 19
chr2_+_118901428 0.304 ENSMUST00000036578.6
Bahd1
bromo adjacent homology domain containing 1
chr17_-_47502276 0.298 ENSMUST00000067103.2
Taf8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq
chr9_-_13826946 0.297 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr7_+_82337218 0.294 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr5_+_145204523 0.291 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr5_+_65131184 0.283 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr17_-_25727364 0.268 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr4_+_132768325 0.268 ENSMUST00000102561.4
Rpa2
replication protein A2
chr10_+_18469958 0.265 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr17_+_25727726 0.252 ENSMUST00000047273.1
Rpusd1
RNA pseudouridylate synthase domain containing 1
chrX_+_95711641 0.236 ENSMUST00000150123.1
Zc3h12b
zinc finger CCCH-type containing 12B
chr10_+_58394381 0.235 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr3_-_54714353 0.234 ENSMUST00000178832.1
Gm21958
predicted gene, 21958
chr5_+_19907502 0.232 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_3513035 0.232 ENSMUST00000036350.2
Cdnf
cerebral dopamine neurotrophic factor
chr14_+_55560480 0.230 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr8_-_83594405 0.226 ENSMUST00000163837.1
Tecr
trans-2,3-enoyl-CoA reductase
chr7_+_113513829 0.217 ENSMUST00000033018.8
Far1
fatty acyl CoA reductase 1
chr13_-_47106176 0.216 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr5_+_135168382 0.214 ENSMUST00000111187.3
ENSMUST00000111188.1
Bcl7b

B cell CLL/lymphoma 7B

chr17_+_79614900 0.209 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr1_-_171287931 0.208 ENSMUST00000111306.3
ENSMUST00000065941.5
Usp21

ubiquitin specific peptidase 21

chr2_+_156008088 0.201 ENSMUST00000088650.4
Ergic3
ERGIC and golgi 3
chr5_+_19907774 0.196 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_42511496 0.192 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr7_-_19715395 0.190 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr8_-_83594440 0.183 ENSMUST00000019382.9
ENSMUST00000165740.1
Tecr

trans-2,3-enoyl-CoA reductase

chr18_-_84086379 0.181 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr11_-_118212715 0.179 ENSMUST00000106302.2
ENSMUST00000151165.1
Cyth1

cytohesin 1

chr2_+_30392405 0.179 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr2_+_156008045 0.174 ENSMUST00000006035.6
Ergic3
ERGIC and golgi 3
chr5_+_135168283 0.174 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr15_-_80014808 0.168 ENSMUST00000000500.6
Pdgfb
platelet derived growth factor, B polypeptide
chr1_-_171287916 0.166 ENSMUST00000111305.1
Usp21
ubiquitin specific peptidase 21
chr2_-_45112890 0.156 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr19_-_29648355 0.152 ENSMUST00000159692.1
Ermp1
endoplasmic reticulum metallopeptidase 1
chr1_+_93512079 0.149 ENSMUST00000120301.1
ENSMUST00000041983.4
ENSMUST00000122402.1
Farp2


FERM, RhoGEF and pleckstrin domain protein 2


chr10_+_58394361 0.145 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr6_+_8259379 0.145 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr11_+_78261717 0.144 ENSMUST00000010421.6
2610507B11Rik
RIKEN cDNA 2610507B11 gene
chr6_+_125145235 0.140 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr3_-_154328634 0.138 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr6_+_8259327 0.134 ENSMUST00000159378.1
Gm16039
predicted gene 16039
chr7_+_25267669 0.130 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr16_+_10835046 0.129 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr11_-_71019233 0.126 ENSMUST00000108523.3
ENSMUST00000143850.1
Derl2

Der1-like domain family, member 2

chr4_+_116221633 0.125 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr13_+_96388294 0.120 ENSMUST00000099295.4
Poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr9_+_21955747 0.116 ENSMUST00000053583.5
Swsap1
SWIM type zinc finger 7 associated protein 1
chr3_+_95588928 0.115 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr6_+_63255971 0.108 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr2_-_58052832 0.107 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr2_-_127133909 0.103 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr7_+_128246812 0.103 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr3_+_95588960 0.099 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr7_+_113513854 0.098 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
Far1



fatty acyl CoA reductase 1



chr3_+_95588990 0.095 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr5_-_120588613 0.094 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr10_+_127290774 0.085 ENSMUST00000026475.8
ENSMUST00000139091.1
Ddit3

DNA-damage inducible transcript 3

chr5_+_57718021 0.083 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr14_-_99099701 0.075 ENSMUST00000042471.9
Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr17_-_26939464 0.059 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr7_+_128246953 0.057 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chrX_-_157415286 0.054 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr1_-_93343482 0.051 ENSMUST00000128253.1
Pask
PAS domain containing serine/threonine kinase
chr11_-_120572822 0.050 ENSMUST00000168360.1
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr7_+_43444104 0.046 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr8_+_57511833 0.043 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr10_+_88459569 0.042 ENSMUST00000020252.3
ENSMUST00000125612.1
Sycp3

synaptonemal complex protein 3

chr15_+_99074968 0.039 ENSMUST00000039665.6
Troap
trophinin associated protein
chr7_-_25754701 0.037 ENSMUST00000108401.1
ENSMUST00000043765.7
Hnrnpul1

heterogeneous nuclear ribonucleoprotein U-like 1

chr4_+_116221590 0.035 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr9_+_61372359 0.030 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

chr6_-_146502099 0.019 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr11_-_120573253 0.018 ENSMUST00000026122.4
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr14_-_31128924 0.009 ENSMUST00000064032.4
ENSMUST00000049732.5
ENSMUST00000090205.3
Smim4


small itegral membrane protein 4


chr8_+_94214567 0.009 ENSMUST00000079961.6
Nup93
nucleoporin 93
chr6_-_8259098 0.007 ENSMUST00000012627.4
Rpa3
replication protein A3
chr8_-_84104773 0.006 ENSMUST00000041367.7
Dcaf15
DDB1 and CUL4 associated factor 15

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.3 2.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 0.9 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.3 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 1.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 0.8 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.2 0.9 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.2 0.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.8 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.2 0.8 GO:0015825 L-serine transport(GO:0015825)
0.2 1.8 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.4 GO:0015747 urate transport(GO:0015747)
0.1 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.1 0.3 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.3 GO:1904778 regulation of metaphase plate congression(GO:0090235) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 2.3 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:0060023 soft palate development(GO:0060023)
0.1 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 2.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.0 0.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.0 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.0 GO:0000802 transverse filament(GO:0000802)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 1.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.8 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 2.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 2.3 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.9 GO:0008276 protein methyltransferase activity(GO:0008276)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.9 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.9 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion