Motif ID: Bhlhe40

Z-value: 0.468


Transcription factors associated with Bhlhe40:

Gene SymbolEntrez IDGene Name
Bhlhe40 ENSMUSG00000030103.5 Bhlhe40

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe40mm10_v2_chr6_+_108660772_1086608740.105.7e-01Click!


Activity profile for motif Bhlhe40.

activity profile for motif Bhlhe40


Sorted Z-values histogram for motif Bhlhe40

Sorted Z-values for motif Bhlhe40



Network of associatons between targets according to the STRING database.



First level regulatory network of Bhlhe40

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_110095937 1.632 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr11_+_97450136 1.225 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr7_+_121707189 1.173 ENSMUST00000065310.2
 1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr11_-_110095974 1.037 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr5_+_65199691 1.002 ENSMUST00000041892.8
 Wdr19
WD repeat domain 19
chr7_+_35802593 0.945 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr4_-_148038769 0.881 ENSMUST00000030879.5
ENSMUST00000137724.1
 Clcn6

chloride channel 6

chr5_+_123252087 0.819 ENSMUST00000121964.1
 Wdr66
WD repeat domain 66
chr16_+_8830093 0.774 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chrX_-_136203637 0.754 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
 Tceal5


transcription elongation factor A (SII)-like 5


chr16_-_44139003 0.711 ENSMUST00000124102.1
 Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr12_-_3426700 0.657 ENSMUST00000180149.1
 1110002L01Rik
RIKEN cDNA 1110002L01 gene
chr12_+_86947343 0.652 ENSMUST00000038369.4
 2310044G17Rik
RIKEN cDNA 2310044G17 gene
chrX_+_136138996 0.644 ENSMUST00000116527.1
 Bex4
brain expressed gene 4
chr3_-_10440054 0.636 ENSMUST00000099223.4
ENSMUST00000029047.6
 Snx16

sorting nexin 16

chr2_+_166805506 0.595 ENSMUST00000099078.3
 Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_-_123572976 0.545 ENSMUST00000031388.8
 Vps33a
vacuolar protein sorting 33A (yeast)
chr4_-_141790891 0.538 ENSMUST00000038014.4
ENSMUST00000153880.1
 Dnajc16

DnaJ (Hsp40) homolog, subfamily C, member 16

chr4_-_48473403 0.519 ENSMUST00000164866.1
ENSMUST00000030030.8
 Tex10

testis expressed gene 10

chr8_+_85036906 0.482 ENSMUST00000093360.4
 Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.3 1.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.7 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.5 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.1 0.4 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0071873 response to norepinephrine(GO:0071873)
0.1 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.2 GO:0046032 ADP catabolic process(GO:0046032)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0005662 male germ cell nucleus(GO:0001673) DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 1.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 PID_ATR_PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC