Motif ID: Bptf

Z-value: 2.719


Transcription factors associated with Bptf:

Gene SymbolEntrez IDGene Name
Bptf ENSMUSG00000040481.10 Bptf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bptfmm10_v2_chr11_-_107131922_1071319540.633.2e-05Click!


Activity profile for motif Bptf.

activity profile for motif Bptf


Sorted Z-values histogram for motif Bptf

Sorted Z-values for motif Bptf



Network of associatons between targets according to the STRING database.



First level regulatory network of Bptf

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_116968969 13.240 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr16_+_43510267 13.129 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr3_+_5218546 12.789 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr18_-_62756275 11.682 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr3_+_5218516 11.278 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr17_+_75178797 10.915 ENSMUST00000112516.1
ENSMUST00000135447.1
 Ltbp1

latent transforming growth factor beta binding protein 1

chr10_-_130280218 10.236 ENSMUST00000061571.3
 Neurod4
neurogenic differentiation 4
chr4_+_144892813 10.104 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr7_-_37769624 10.080 ENSMUST00000175941.1
 Zfp536
zinc finger protein 536
chr1_-_97977233 9.974 ENSMUST00000161567.1
 Pam
peptidylglycine alpha-amidating monooxygenase
chr11_+_44617310 9.942 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr5_-_123012874 9.902 ENSMUST00000172729.1
 Kdm2b
lysine (K)-specific demethylase 2B
chr14_-_47411666 9.225 ENSMUST00000111778.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr16_+_37916440 9.130 ENSMUST00000061274.7
 Gpr156
G protein-coupled receptor 156
chr2_-_118549668 8.977 ENSMUST00000090219.6
 Bmf
BCL2 modifying factor
chr3_+_5218589 8.676 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr3_-_121171678 8.522 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
 Rwdd3




RWD domain containing 3




chr18_-_13972617 8.230 ENSMUST00000025288.7
 Zfp521
zinc finger protein 521
chr6_+_134929118 8.230 ENSMUST00000185152.1
ENSMUST00000184504.1
 RP23-45G16.5

RP23-45G16.5

chr1_+_20917856 8.205 ENSMUST00000167119.1
 Paqr8
progestin and adipoQ receptor family member VIII

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 405 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 36.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.9 36.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 19.4 GO:0008360 regulation of cell shape(GO:0008360)
3.6 17.8 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.7 17.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.4 13.8 GO:0060325 face morphogenesis(GO:0060325)
1.4 13.0 GO:0048102 autophagic cell death(GO:0048102)
1.6 12.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.9 12.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 11.9 GO:0031529 ruffle organization(GO:0031529)
0.4 11.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.4 11.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 11.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.8 10.2 GO:0035881 amacrine cell differentiation(GO:0035881)
2.0 10.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 10.0 GO:0009404 toxin metabolic process(GO:0009404)
0.3 9.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.8 9.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 9.2 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.6 8.9 GO:0034501 protein localization to kinetochore(GO:0034501)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 159 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 82.8 GO:0005634 nucleus(GO:0005634)
5.8 17.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 16.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 15.4 GO:0043296 apical junction complex(GO:0043296)
0.7 14.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 13.1 GO:0016459 myosin complex(GO:0016459)
1.3 12.9 GO:0000796 condensin complex(GO:0000796)
0.3 12.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 11.9 GO:0043197 dendritic spine(GO:0043197)
1.3 11.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 11.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
1.3 10.7 GO:0005818 aster(GO:0005818)
0.3 9.3 GO:0035371 microtubule plus-end(GO:0035371)
0.5 8.6 GO:0000800 lateral element(GO:0000800)
0.1 8.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 8.1 GO:0036126 sperm flagellum(GO:0036126)
0.5 8.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.4 7.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 7.6 GO:0005876 spindle microtubule(GO:0005876)
0.2 7.6 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 254 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 42.6 GO:0008270 zinc ion binding(GO:0008270)
0.2 39.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
3.3 23.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 20.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
4.4 17.5 GO:0050436 microfibril binding(GO:0050436)
0.1 15.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 14.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.9 13.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.4 12.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
3.9 11.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.6 11.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 10.9 GO:0003785 actin monomer binding(GO:0003785)
1.7 10.5 GO:0001972 retinoic acid binding(GO:0001972)
0.3 10.2 GO:0070182 DNA polymerase binding(GO:0070182)
3.3 10.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.7 9.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.5 9.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.5 9.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.7 8.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.6 8.8 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 36.6 PID_PLK1_PATHWAY PLK1 signaling events
0.2 32.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.4 26.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.5 21.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.5 14.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 13.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.2 12.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.2 11.4 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.2 9.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 7.8 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.8 7.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 6.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 6.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 6.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 6.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 6.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 5.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.3 5.6 PID_IL5_PATHWAY IL5-mediated signaling events
0.2 4.6 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 4.4 PID_ATM_PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 19.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.8 17.9 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 13.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 12.7 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 11.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.6 9.6 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 8.3 REACTOME_KINESINS Genes involved in Kinesins
0.6 8.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 7.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
2.3 6.8 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 6.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.4 5.8 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.5 5.4 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.5 5.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.5 5.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 4.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 4.6 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 4.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5 4.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 4.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels