Motif ID: Bsx

Z-value: 0.442


Transcription factors associated with Bsx:

Gene SymbolEntrez IDGene Name
Bsx ENSMUSG00000054360.3 Bsx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bsxmm10_v2_chr9_+_40873981_408741270.086.3e-01Click!


Activity profile for motif Bsx.

activity profile for motif Bsx


Sorted Z-values histogram for motif Bsx

Sorted Z-values for motif Bsx



Network of associatons between targets according to the STRING database.



First level regulatory network of Bsx

PNG image of the network

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Top targets:


Showing 1 to 20 of 84 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_8710734 3.540 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 2.629 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_14621805 2.098 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr3_-_121263314 1.658 ENSMUST00000029777.7
 Tmem56
transmembrane protein 56
chr11_-_98053415 1.535 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr15_+_78926720 1.493 ENSMUST00000089377.5
 Lgals1
lectin, galactose binding, soluble 1
chr2_+_116067213 1.490 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr2_-_113829069 1.365 ENSMUST00000024005.7
 Scg5
secretogranin V
chr3_+_54361103 1.288 ENSMUST00000107985.3
ENSMUST00000117373.1
ENSMUST00000073012.6
ENSMUST00000081564.6
 Postn



periostin, osteoblast specific factor



chr17_-_47833169 1.266 ENSMUST00000131971.1
ENSMUST00000129360.1
ENSMUST00000113280.1
ENSMUST00000132125.1
 Mdfi



MyoD family inhibitor



chr18_+_69346143 1.259 ENSMUST00000114980.1
 Tcf4
transcription factor 4
chr13_-_105054895 1.254 ENSMUST00000063551.5
 Rgs7bp
regulator of G-protein signalling 7 binding protein
chr3_-_113577743 1.226 ENSMUST00000067980.5
 Amy1
amylase 1, salivary
chr17_-_47833256 1.159 ENSMUST00000152455.1
ENSMUST00000035375.7
 Mdfi

MyoD family inhibitor

chr11_-_109611417 1.039 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
 Wipi1


WD repeat domain, phosphoinositide interacting 1


chrX_+_13632769 0.963 ENSMUST00000096492.3
 Gpr34
G protein-coupled receptor 34
chr5_+_134932351 0.929 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
 Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr5_-_62766153 0.907 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_14621494 0.900 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr6_+_29694204 0.887 ENSMUST00000046750.7
ENSMUST00000115250.3
 Tspan33

tetraspanin 33


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 3.6 GO:0019532 oxalate transport(GO:0019532)
0.1 2.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.6 GO:0061157 mRNA destabilization(GO:0061157)
0.2 1.5 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.1 1.4 GO:0016486 peptide hormone processing(GO:0016486)
0.4 1.3 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 1.0 GO:0048199 protein localization to pre-autophagosomal structure(GO:0034497) vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.7 GO:0032570 response to progesterone(GO:0032570)
0.2 0.6 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.5 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.5 GO:0033572 transferrin transport(GO:0033572)
0.0 0.5 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.4 GO:0035633 negative regulation of norepinephrine secretion(GO:0010700) maintenance of blood-brain barrier(GO:0035633)
0.1 0.4 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 6.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 3.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.3 1.5 GO:0005534 galactose binding(GO:0005534)
0.0 1.5 GO:0051082 unfolded protein binding(GO:0051082)
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.3 GO:0008201 heparin binding(GO:0008201)
0.4 1.2 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) thiolester hydrolase activity(GO:0016790)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.6 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis