Motif ID: Cdc5l

Z-value: 0.565


Transcription factors associated with Cdc5l:

Gene SymbolEntrez IDGene Name
Cdc5l ENSMUSG00000023932.8 Cdc5l

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cdc5lmm10_v2_chr17_-_45433682_454337090.047.9e-01Click!


Activity profile for motif Cdc5l.

activity profile for motif Cdc5l


Sorted Z-values histogram for motif Cdc5l

Sorted Z-values for motif Cdc5l



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdc5l

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_31447383 2.713 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr5_+_66968559 2.646 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr9_-_112187766 2.642 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_+_65620829 2.531 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr9_-_112187898 2.510 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_66968416 2.392 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr12_+_74297474 1.788 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr12_+_29528382 1.615 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr2_-_64975762 1.413 ENSMUST00000156765.1
 Grb14
growth factor receptor bound protein 14
chr19_+_26749726 1.384 ENSMUST00000175842.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_107497762 1.365 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr4_-_149126688 1.328 ENSMUST00000030815.2
 Cort
cortistatin
chr5_+_107497718 1.202 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr3_-_49757257 1.113 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr17_-_78684262 1.045 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr1_+_143640664 0.930 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr9_-_55919605 0.724 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr18_-_22850738 0.649 ENSMUST00000092015.4
ENSMUST00000069215.6
 Nol4

nucleolar protein 4

chr15_-_13173607 0.578 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr1_+_180111339 0.554 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr5_-_31220491 0.464 ENSMUST00000031032.7
 Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr2_+_106695594 0.402 ENSMUST00000016530.7
 Mpped2
metallophosphoesterase domain containing 2
chr9_-_96752822 0.339 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr5_-_136883115 0.325 ENSMUST00000057497.6
ENSMUST00000111103.1
 Col26a1

collagen, type XXVI, alpha 1

chr4_+_95967205 0.292 ENSMUST00000030306.7
 Hook1
hook homolog 1 (Drosophila)
chr1_-_30863256 0.284 ENSMUST00000088310.3
 Phf3
PHD finger protein 3
chr7_+_130577334 0.271 ENSMUST00000059145.7
ENSMUST00000084513.4
 Tacc2

transforming, acidic coiled-coil containing protein 2

chrX_+_136822671 0.246 ENSMUST00000033800.6
 Plp1
proteolipid protein (myelin) 1
chrX_+_136822781 0.237 ENSMUST00000113085.1
 Plp1
proteolipid protein (myelin) 1
chr13_-_18382041 0.132 ENSMUST00000139064.2
ENSMUST00000175703.2
 Pou6f2

POU domain, class 6, transcription factor 2

chr1_+_17601893 0.090 ENSMUST00000088476.2
 Pi15
peptidase inhibitor 15
chr15_-_103215285 0.069 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chr4_-_119383732 0.054 ENSMUST00000044781.2
ENSMUST00000084307.3
 Ccdc30

coiled-coil domain containing 30

chr2_-_72986716 0.036 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr7_-_103741322 0.036 ENSMUST00000051346.2
 Olfr629
olfactory receptor 629
chrX_-_37104523 0.027 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 2.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 5.2 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 5.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.6 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 5.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 5.3 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling