Motif ID: Cebpa_Cebpg

Z-value: 0.680

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpgmm10_v2_chr7_-_35056467_35056556-0.609.7e-05Click!
Cebpamm10_v2_chr7_+_35119285_351193010.212.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_57239310 5.187 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr9_-_121495678 3.111 ENSMUST00000035120.4
Cck
cholecystokinin
chr6_+_17463749 2.681 ENSMUST00000115443.1
Met
met proto-oncogene
chrX_-_162565514 2.558 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr13_-_117025505 2.367 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr12_+_74297474 2.325 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr14_+_65970610 2.215 ENSMUST00000127387.1
Clu
clusterin
chr1_-_22315792 2.058 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr14_+_65971049 2.012 ENSMUST00000128539.1
Clu
clusterin
chr1_-_38821215 1.994 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr1_-_71653162 1.963 ENSMUST00000055226.6
Fn1
fibronectin 1
chr4_-_15149051 1.689 ENSMUST00000041606.7
Necab1
N-terminal EF-hand calcium binding protein 1
chr13_-_49309217 1.672 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr7_-_103813913 1.550 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr14_+_65971164 1.460 ENSMUST00000144619.1
Clu
clusterin
chr14_+_65970804 1.423 ENSMUST00000138191.1
Clu
clusterin
chr4_-_15149755 1.268 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr1_+_169655493 1.194 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr3_+_31902666 1.177 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr2_-_45117349 1.097 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr3_-_142169196 1.088 ENSMUST00000098568.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr3_+_19957037 1.041 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr6_+_96115249 0.998 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr4_+_136143497 0.987 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr1_-_37496095 0.973 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr4_+_85205120 0.945 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr11_-_110095937 0.935 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr7_-_79149042 0.931 ENSMUST00000032825.8
ENSMUST00000107409.3
Mfge8

milk fat globule-EGF factor 8 protein

chr6_-_7693184 0.916 ENSMUST00000031766.5
Asns
asparagine synthetase
chr3_-_142169311 0.910 ENSMUST00000106230.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr2_-_57113053 0.866 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr15_-_88978958 0.859 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr11_-_120643643 0.844 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr13_+_24614608 0.832 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr11_-_42000834 0.817 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chrX_+_73064787 0.810 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr6_-_99028874 0.809 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr11_-_35798884 0.769 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr13_+_109903089 0.755 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr9_+_94669876 0.736 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr13_+_31806627 0.732 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr2_-_65567465 0.714 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_-_51567717 0.691 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr18_+_37489465 0.672 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr2_-_65567505 0.648 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_+_129532386 0.632 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr9_+_37367354 0.630 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr3_-_50443603 0.623 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr18_-_64516547 0.582 ENSMUST00000025483.9
Nars
asparaginyl-tRNA synthetase
chr16_-_4559720 0.556 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr11_-_84870712 0.539 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr11_-_84870646 0.535 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr4_+_55350043 0.520 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr14_-_18893376 0.479 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr10_+_80930071 0.475 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chrX_+_135993820 0.451 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr17_+_48346465 0.449 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr11_+_53433299 0.438 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr1_+_137966529 0.436 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr17_+_48346401 0.432 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chr8_-_86580664 0.430 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr5_+_114444266 0.408 ENSMUST00000043760.8
ENSMUST00000112239.2
ENSMUST00000125650.1
Mvk


mevalonate kinase


chr11_-_106216318 0.397 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr10_-_64090241 0.386 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chrX_+_74297097 0.380 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chr11_-_84870812 0.359 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chr7_-_19715395 0.359 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr14_+_51091077 0.351 ENSMUST00000022428.5
ENSMUST00000171688.1
Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr16_-_34095983 0.347 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr1_+_134494628 0.337 ENSMUST00000047978.7
Rabif
RAB interacting factor
chr10_-_117292863 0.335 ENSMUST00000092162.5
Lyz1
lysozyme 1
chr2_-_52676571 0.335 ENSMUST00000178799.1
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr1_+_60343297 0.327 ENSMUST00000114202.1
ENSMUST00000060608.6
Cyp20a1

cytochrome P450, family 20, subfamily a, polypeptide 1

chr11_+_78037959 0.305 ENSMUST00000073660.6
Flot2
flotillin 2
chr3_+_106113229 0.304 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr13_-_56895737 0.298 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr18_-_52529692 0.297 ENSMUST00000025409.7
Lox
lysyl oxidase
chr18_-_52529847 0.285 ENSMUST00000171470.1
Lox
lysyl oxidase
chr17_+_35823509 0.283 ENSMUST00000173493.1
ENSMUST00000173147.1
ENSMUST00000172846.1
Flot1


flotillin 1


chr19_+_34290653 0.282 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr10_-_13552838 0.273 ENSMUST00000105541.1
Pex3
peroxisomal biogenesis factor 3
chr16_+_3847206 0.267 ENSMUST00000041778.7
Zfp174
zinc finger protein 174
chr5_-_138171216 0.265 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_-_127273919 0.262 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr17_+_35823230 0.260 ENSMUST00000001569.8
ENSMUST00000174080.1
Flot1

flotillin 1

chr9_-_8134294 0.250 ENSMUST00000037397.6
AK129341
cDNA sequence AK129341
chr4_-_36136463 0.229 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr7_-_25754701 0.222 ENSMUST00000108401.1
ENSMUST00000043765.7
Hnrnpul1

heterogeneous nuclear ribonucleoprotein U-like 1

chr11_+_75732869 0.221 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr5_-_137533170 0.219 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr17_+_35841491 0.216 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr18_-_34931993 0.216 ENSMUST00000025218.7
Etf1
eukaryotic translation termination factor 1
chr2_-_129371131 0.209 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr2_+_155751117 0.207 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chrX_+_6047453 0.204 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr2_+_82053222 0.198 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr3_+_51559757 0.197 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chrX_+_94636066 0.194 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr10_+_69925766 0.192 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr5_-_92083667 0.189 ENSMUST00000113127.3
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr7_+_110777653 0.189 ENSMUST00000148292.1
Ampd3
adenosine monophosphate deaminase 3
chr9_+_78615501 0.187 ENSMUST00000093812.4
Cd109
CD109 antigen
chr6_+_54326955 0.182 ENSMUST00000059138.4
Prr15
proline rich 15
chr7_+_3645267 0.178 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr9_+_107975529 0.178 ENSMUST00000035216.4
Uba7
ubiquitin-like modifier activating enzyme 7
chr4_-_36056726 0.172 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr10_+_39369750 0.169 ENSMUST00000063091.6
ENSMUST00000099967.3
ENSMUST00000126486.1
Fyn


Fyn proto-oncogene


chr19_-_8818924 0.153 ENSMUST00000153281.1
Ttc9c
tetratricopeptide repeat domain 9C
chr11_+_6415443 0.149 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chrX_+_153498202 0.147 ENSMUST00000060714.8
Ubqln2
ubiquilin 2
chr10_+_69925484 0.146 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr10_-_25297055 0.134 ENSMUST00000177124.1
Akap7
A kinase (PRKA) anchor protein 7
chr3_-_107986408 0.132 ENSMUST00000012348.2
Gstm2
glutathione S-transferase, mu 2
chr6_-_118455475 0.131 ENSMUST00000161519.1
ENSMUST00000069292.7
Zfp248

zinc finger protein 248

chr2_+_22895482 0.131 ENSMUST00000053729.7
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chrX_-_74428871 0.127 ENSMUST00000143521.1
G6pdx
glucose-6-phosphate dehydrogenase X-linked
chr3_+_66219909 0.124 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr18_+_20944607 0.123 ENSMUST00000050004.1
Rnf125
ring finger protein 125
chr2_-_32424005 0.121 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr3_+_7612702 0.117 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr12_-_56535047 0.115 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr11_+_59306920 0.115 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr3_-_107986360 0.111 ENSMUST00000066530.6
Gstm2
glutathione S-transferase, mu 2
chr12_-_111377705 0.110 ENSMUST00000041965.3
Cdc42bpb
CDC42 binding protein kinase beta
chr17_+_32284772 0.109 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr2_-_152831665 0.107 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr15_-_58214882 0.105 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr5_+_115279666 0.103 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr14_-_45477856 0.103 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr14_+_32165784 0.103 ENSMUST00000111994.3
ENSMUST00000168114.1
ENSMUST00000168034.1
Ncoa4


nuclear receptor coactivator 4


chr2_+_32876114 0.100 ENSMUST00000028135.8
Fam129b
family with sequence similarity 129, member B
chr2_-_144011202 0.098 ENSMUST00000016072.5
ENSMUST00000037875.5
Rrbp1

ribosome binding protein 1

chr10_+_69925800 0.094 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr19_-_7341792 0.093 ENSMUST00000164205.1
ENSMUST00000165286.1
ENSMUST00000168324.1
ENSMUST00000032557.8
Mark2



MAP/microtubule affinity-regulating kinase 2



chr13_+_51100810 0.090 ENSMUST00000095797.5
Spin1
spindlin 1
chr5_+_30889326 0.086 ENSMUST00000124908.1
Agbl5
ATP/GTP binding protein-like 5
chr14_+_32166104 0.083 ENSMUST00000164341.1
Ncoa4
nuclear receptor coactivator 4
chr8_-_94601720 0.079 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr7_+_6474088 0.075 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr5_-_147894804 0.069 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr2_+_71055731 0.065 ENSMUST00000154704.1
ENSMUST00000135357.1
ENSMUST00000064141.5
ENSMUST00000112159.2
ENSMUST00000102701.3
Dcaf17




DDB1 and CUL4 associated factor 17




chr17_-_35235755 0.062 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr8_-_46211284 0.057 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr5_-_145140238 0.052 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr10_-_62651194 0.051 ENSMUST00000020270.4
Ddx50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr3_-_82876483 0.043 ENSMUST00000048647.7
Rbm46
RNA binding motif protein 46
chr4_-_130359915 0.042 ENSMUST00000134159.2
Zcchc17
zinc finger, CCHC domain containing 17
chr11_+_106216926 0.041 ENSMUST00000021046.5
Ddx42
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr4_-_58911902 0.040 ENSMUST00000134848.1
ENSMUST00000107557.2
ENSMUST00000149301.1
AI314180


expressed sequence AI314180


chr1_-_65051119 0.039 ENSMUST00000161960.1
ENSMUST00000087359.5
Cryge

crystallin, gamma E

chr8_+_94601928 0.036 ENSMUST00000060389.8
ENSMUST00000121101.1
Rspry1

ring finger and SPRY domain containing 1

chr11_+_23020464 0.035 ENSMUST00000094363.3
ENSMUST00000151877.1
Fam161a

family with sequence similarity 161, member A

chr5_+_30013141 0.034 ENSMUST00000026845.7
Il6
interleukin 6
chr4_-_63495951 0.032 ENSMUST00000063650.3
ENSMUST00000102867.1
ENSMUST00000107393.1
ENSMUST00000084510.1
ENSMUST00000095038.1
ENSMUST00000119294.1
ENSMUST00000095037.1
ENSMUST00000063672.3
Whrn







whirlin







chr12_+_105032638 0.029 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr3_-_108086590 0.023 ENSMUST00000102638.1
ENSMUST00000102637.1
Ampd2

adenosine monophosphate deaminase 2

chr15_+_87625214 0.018 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr9_+_110419750 0.015 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chrX_+_99821021 0.015 ENSMUST00000096363.2
Tmem28
transmembrane protein 28
chr7_+_103550368 0.005 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr7_-_45434590 0.004 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2

RuvB-like protein 2

chrX_+_159459125 0.002 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
Map7d2


MAP7 domain containing 2


chr4_+_115059507 0.002 ENSMUST00000162489.1
Tal1
T cell acute lymphocytic leukemia 1
chr19_-_15924928 0.001 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr7_-_100371889 0.000 ENSMUST00000032963.8
Ppme1
protein phosphatase methylesterase 1
chr15_+_9140527 0.000 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 2.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.5 2.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.5 2.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 2.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 3.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.3 0.9 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.3 1.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 2.2 GO:0017085 response to insecticide(GO:0017085)
0.2 0.7 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.2 0.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 0.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 1.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 0.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 0.8 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.6 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:0060558 regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.5 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.4 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.8 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.1 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.1 GO:0002034 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.1 0.8 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.0 GO:0046688 response to copper ion(GO:0046688)
0.1 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 1.0 GO:0030903 notochord development(GO:0030903)
0.0 0.4 GO:0006983 ER overload response(GO:0006983)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) action potential propagation(GO:0098870)
0.0 0.1 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.2 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0052490 suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) response to cycloheximide(GO:0046898) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 1.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 1.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0070527 platelet aggregation(GO:0070527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.7 2.0 GO:0005577 fibrinogen complex(GO:0005577)
0.4 2.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 3.1 GO:0043203 axon hillock(GO:0043203)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 5.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 1.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 2.0 GO:0045340 mercury ion binding(GO:0045340)
0.3 7.1 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.9 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 2.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.9 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.6 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 3.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.4 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 2.1 GO:0044325 ion channel binding(GO:0044325)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 6.9 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.7 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.9 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 3.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.0 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 7.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.7 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 3.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling