Motif ID: Cebpb

Z-value: 1.026


Transcription factors associated with Cebpb:

Gene SymbolEntrez IDGene Name
Cebpb ENSMUSG00000056501.3 Cebpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpbmm10_v2_chr2_+_167688915_1676889730.651.2e-05Click!


Activity profile for motif Cebpb.

activity profile for motif Cebpb


Sorted Z-values histogram for motif Cebpb

Sorted Z-values for motif Cebpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 166 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_57239310 4.989 ENSMUST00000111559.1
 Ablim1
actin-binding LIM protein 1
chrX_-_162565514 4.935 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr17_+_57358682 4.686 ENSMUST00000086763.5
ENSMUST00000004850.7
 Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr19_+_12460749 4.340 ENSMUST00000081035.7
 Mpeg1
macrophage expressed gene 1
chr1_-_71653162 4.083 ENSMUST00000055226.6
 Fn1
fibronectin 1
chr1_-_38821215 3.980 ENSMUST00000039612.4
 Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr15_-_37459327 3.940 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr2_-_25469742 3.847 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr1_+_169655493 3.704 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr2_-_25470031 3.689 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr17_+_48346401 3.612 ENSMUST00000024791.8
 Trem2
triggering receptor expressed on myeloid cells 2
chr17_+_48346465 3.598 ENSMUST00000113237.3
 Trem2
triggering receptor expressed on myeloid cells 2
chr19_+_6401675 3.432 ENSMUST00000113471.1
ENSMUST00000113469.2
 Rasgrp2

RAS, guanyl releasing protein 2

chr12_+_74297474 3.360 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr11_-_83649349 3.343 ENSMUST00000001008.5
 Ccl3
chemokine (C-C motif) ligand 3
chr5_+_75152274 3.284 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr10_+_97482350 3.219 ENSMUST00000163448.2
 Dcn
decorin
chr3_+_123446913 3.185 ENSMUST00000029603.8
 Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr6_+_17463749 3.095 ENSMUST00000115443.1
 Met
met proto-oncogene
chr8_+_66386292 3.091 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 10.0 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.5 7.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
2.4 7.2 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.1 7.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 4.9 GO:0030032 lamellipodium assembly(GO:0030032)
1.4 4.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.1 3.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 3.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
1.1 3.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.4 3.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 3.2 GO:0031638 zymogen activation(GO:0031638)
0.4 3.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 3.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.3 2.9 GO:0044539 long-chain fatty acid import(GO:0044539)
0.4 2.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 2.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.7 2.6 GO:1904706 heme oxidation(GO:0006788) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.5 2.6 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 2.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 2.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 10.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 9.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
1.5 4.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 3.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.3 GO:0005902 microvillus(GO:0005902)
0.2 3.2 GO:0043083 synaptic cleft(GO:0043083)
0.2 3.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 3.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.9 2.6 GO:0043512 inhibin A complex(GO:0043512)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.6 GO:0005901 caveola(GO:0005901)
0.5 2.5 GO:0001533 cornified envelope(GO:0001533)
0.3 2.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.5 2.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.6 1.9 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.9 GO:0043203 axon hillock(GO:0043203)
0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 1.4 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 10.0 GO:0051787 misfolded protein binding(GO:0051787)
2.3 9.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.9 7.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 7.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 4.6 GO:0005518 collagen binding(GO:0005518)
0.1 4.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.7 4.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.7 3.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 3.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 3.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.8 3.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 3.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
1.0 2.9 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 2.7 GO:0042287 MHC protein binding(GO:0042287)
0.7 2.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.6 2.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.4 2.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.2 5.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 4.2 PID_IL12_2PATHWAY IL12-mediated signaling events
0.2 4.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 3.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 3.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.6 PID_ALK1_PATHWAY ALK1 signaling events
0.0 2.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.7 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 12.7 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 7.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 6.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.3 6.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 5.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 5.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 5.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.4 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 3.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.3 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.2 3.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 3.1 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.1 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.1 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.9 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6 2.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 2.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 2.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.2 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 1.7 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism