Motif ID: Cebpe

Z-value: 1.064


Transcription factors associated with Cebpe:

Gene SymbolEntrez IDGene Name
Cebpe ENSMUSG00000052435.6 Cebpe



Activity profile for motif Cebpe.

activity profile for motif Cebpe


Sorted Z-values histogram for motif Cebpe

Sorted Z-values for motif Cebpe



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpe

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_50944499 8.395 ENSMUST00000178092.1
 Pnp
purine-nucleoside phosphorylase
chr7_-_103853199 6.935 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr10_-_92165159 6.868 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr4_-_117182623 5.193 ENSMUST00000065896.2
 Kif2c
kinesin family member 2C
chr9_-_100506844 5.019 ENSMUST00000112874.3
 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr1_+_6487231 4.673 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr7_+_67647405 4.357 ENSMUST00000032774.8
ENSMUST00000107471.1
 Ttc23

tetratricopeptide repeat domain 23

chr2_-_69206146 4.171 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
 Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr16_-_22161450 4.140 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_69206133 3.925 ENSMUST00000112320.1
 Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_+_51880312 3.709 ENSMUST00000145049.1
 Gas2
growth arrest specific 2
chr2_-_129297205 3.484 ENSMUST00000052708.6
 Ckap2l
cytoskeleton associated protein 2-like
chr6_+_56017489 3.479 ENSMUST00000052827.4
 Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr7_-_137314394 3.343 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr11_-_76399107 3.107 ENSMUST00000021204.3
 Nxn
nucleoredoxin
chrX_+_112311334 3.021 ENSMUST00000026599.3
ENSMUST00000113415.1
 Apool

apolipoprotein O-like

chr17_+_21691860 2.838 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr17_+_21690766 2.714 ENSMUST00000097384.1
 Gm10509
predicted gene 10509
chr7_+_75610038 2.683 ENSMUST00000125771.1
 Akap13
A kinase (PRKA) anchor protein 13
chr11_+_69045640 2.683 ENSMUST00000108666.1
ENSMUST00000021277.5
 Aurkb

aurora kinase B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 275 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 12.0 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.7 8.7 GO:0015671 oxygen transport(GO:0015671)
2.8 8.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 8.0 GO:0007052 mitotic spindle organization(GO:0007052)
1.0 5.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.7 5.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 5.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.4 4.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 3.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 3.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 3.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 3.6 GO:0001947 heart looping(GO:0001947)
0.0 3.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.8 3.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 3.0 GO:0042407 cristae formation(GO:0042407)
0.0 3.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 2.9 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.9 2.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 2.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.9 2.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 134 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.7 GO:0005833 hemoglobin complex(GO:0005833)
1.3 8.1 GO:0031262 Ndc80 complex(GO:0031262)
0.1 5.7 GO:0005814 centriole(GO:0005814)
0.2 5.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.6 GO:0016607 nuclear speck(GO:0016607)
0.3 4.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 3.9 GO:0070545 PeBoW complex(GO:0070545)
0.1 3.9 GO:0005882 intermediate filament(GO:0005882)
0.6 3.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 3.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 3.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 3.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 3.2 GO:0072686 mitotic spindle(GO:0072686)
0.3 3.0 GO:0061617 MICOS complex(GO:0061617)
0.5 2.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 2.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.3 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 189 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 10.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
2.2 8.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 8.1 GO:0008017 microtubule binding(GO:0008017)
0.3 5.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 5.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 4.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 3.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 3.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.5 2.9 GO:0005042 netrin receptor activity(GO:0005042)
0.0 2.8 GO:0003684 damaged DNA binding(GO:0003684)
0.5 2.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 2.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 2.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 2.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 2.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.1 GO:0005521 lamin binding(GO:0005521)
0.4 2.0 GO:0008172 S-methyltransferase activity(GO:0008172)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 7.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 5.4 PID_BARD1_PATHWAY BARD1 signaling events
0.1 4.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 4.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 4.1 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 2.5 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 2.2 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 1.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 1.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 19.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.9 9.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.3 5.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 3.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 3.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.3 2.9 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.9 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 2.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.3 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.2 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.0 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.1 1.9 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)