Motif ID: Cenpb

Z-value: 1.116


Transcription factors associated with Cenpb:

Gene SymbolEntrez IDGene Name
Cenpb ENSMUSG00000068267.4 Cenpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cenpbmm10_v2_chr2_-_131179985_131180092-0.381.9e-02Click!


Activity profile for motif Cenpb.

activity profile for motif Cenpb


Sorted Z-values histogram for motif Cenpb

Sorted Z-values for motif Cenpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cenpb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_98662227 14.495 ENSMUST00000099684.3
Gm10801
predicted gene 10801
chr2_+_172550991 9.166 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr1_-_138848576 4.167 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr8_-_87959560 3.761 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr4_-_68954351 3.736 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr19_+_47014672 3.671 ENSMUST00000037636.3
Ina
internexin neuronal intermediate filament protein, alpha
chr7_-_137314394 3.589 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr14_+_65805832 3.222 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr17_+_87282880 3.086 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr16_-_17125106 2.966 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr14_+_65806066 2.806 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr8_-_122678653 2.704 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr12_-_45074112 2.580 ENSMUST00000120531.1
ENSMUST00000143376.1
Stxbp6

syntaxin binding protein 6 (amisyn)

chr4_-_119232661 2.501 ENSMUST00000141112.1
AU022252
expressed sequence AU022252
chr6_+_66535418 2.451 ENSMUST00000101343.1
Mad2l1
MAD2 mitotic arrest deficient-like 1
chr11_-_33147400 2.414 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr11_-_4746778 2.413 ENSMUST00000009219.2
Cabp7
calcium binding protein 7
chr10_+_50895651 2.154 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr9_+_48495345 2.122 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr16_+_81200697 2.086 ENSMUST00000067602.3
ENSMUST00000037785.7
Ncam2

neural cell adhesion molecule 2

chr15_-_76126538 1.989 ENSMUST00000054022.5
ENSMUST00000089654.3
BC024139

cDNA sequence BC024139

chr6_-_56362356 1.983 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr12_-_45074457 1.948 ENSMUST00000053768.6
Stxbp6
syntaxin binding protein 6 (amisyn)
chr3_+_75557530 1.816 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr10_+_67979709 1.806 ENSMUST00000117086.1
Rtkn2
rhotekin 2
chr10_+_25359798 1.721 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr10_-_18546049 1.677 ENSMUST00000020000.5
Hebp2
heme binding protein 2
chr16_-_10543028 1.636 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr15_-_76521902 1.633 ENSMUST00000164703.1
ENSMUST00000096365.3
Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr7_-_118855984 1.601 ENSMUST00000116280.2
ENSMUST00000106550.3
ENSMUST00000063607.5
Knop1


lysine rich nucleolar protein 1


chr11_+_101316917 1.584 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr16_+_58408443 1.576 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr13_-_23698454 1.564 ENSMUST00000102967.1
Hist1h4c
histone cluster 1, H4c
chr6_+_85187438 1.495 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr7_-_118856254 1.476 ENSMUST00000033277.7
Knop1
lysine rich nucleolar protein 1
chr2_+_168081004 1.458 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr6_+_4755327 1.439 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr1_+_184034381 1.434 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr3_+_19188288 1.434 ENSMUST00000132035.1
Mtfr1
mitochondrial fission regulator 1
chr19_-_4928241 1.424 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr7_-_118855602 1.341 ENSMUST00000106549.1
ENSMUST00000126792.1
Knop1

lysine rich nucleolar protein 1

chr7_-_133123770 1.340 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr7_+_45434833 1.323 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr5_-_131538687 1.320 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr3_+_123267445 1.313 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr14_-_15438974 1.311 ENSMUST00000055211.4
Lrrc3b
leucine rich repeat containing 3B
chr7_+_45434876 1.310 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr9_+_44379536 1.294 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr1_+_75521521 1.293 ENSMUST00000027414.9
ENSMUST00000113553.1
Stk11ip

serine/threonine kinase 11 interacting protein

chr5_-_135394499 1.275 ENSMUST00000065638.4
ENSMUST00000111171.2
Pom121

nuclear pore membrane protein 121

chr5_-_142906702 1.255 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr9_+_44379490 1.244 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr17_+_31057686 1.244 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr10_+_67979592 1.238 ENSMUST00000105437.1
Rtkn2
rhotekin 2
chr15_+_72913357 1.236 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chr6_+_117907795 1.217 ENSMUST00000167657.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr10_+_67979569 1.172 ENSMUST00000118160.1
Rtkn2
rhotekin 2
chr12_-_67221221 1.150 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr14_+_66297029 1.145 ENSMUST00000022623.6
ENSMUST00000121006.1
Trim35

tripartite motif-containing 35

chr5_-_99037342 1.118 ENSMUST00000161490.1
Prkg2
protein kinase, cGMP-dependent, type II
chr6_-_94700137 1.085 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr2_+_28468056 1.070 ENSMUST00000038600.3
Mrps2
mitochondrial ribosomal protein S2
chr18_+_10725651 1.063 ENSMUST00000165555.1
Mib1
mindbomb homolog 1 (Drosophila)
chr8_-_104641666 1.057 ENSMUST00000093234.4
Fam96b
family with sequence similarity 96, member B
chr15_+_61987410 1.042 ENSMUST00000160009.1
Myc
myelocytomatosis oncogene
chr7_-_133123409 1.035 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr15_-_33405976 1.030 ENSMUST00000079057.6
1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr9_-_36726374 0.999 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chrX_-_143827391 0.947 ENSMUST00000087316.5
Capn6
calpain 6
chr1_-_25829511 0.937 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr14_+_70077375 0.932 ENSMUST00000035908.1
Egr3
early growth response 3
chr18_-_84685615 0.928 ENSMUST00000025546.9
Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr7_-_5014645 0.916 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr2_-_122369130 0.894 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr14_+_66635251 0.885 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
Adra1a


adrenergic receptor, alpha 1a


chr8_-_25201349 0.880 ENSMUST00000084512.4
ENSMUST00000084030.4
Tacc1

transforming, acidic coiled-coil containing protein 1

chr9_-_8004585 0.879 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr11_-_113751309 0.878 ENSMUST00000106616.1
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr8_+_4349588 0.869 ENSMUST00000110982.1
ENSMUST00000024004.7
Ccl25

chemokine (C-C motif) ligand 25

chr6_-_47813512 0.859 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr11_+_88099146 0.846 ENSMUST00000018522.6
Cuedc1
CUE domain containing 1
chr2_-_26352067 0.828 ENSMUST00000028295.8
Dnlz
DNL-type zinc finger
chr16_+_52031549 0.828 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr3_-_63899437 0.826 ENSMUST00000159188.1
ENSMUST00000177143.1
Plch1

phospholipase C, eta 1

chr11_+_101448403 0.808 ENSMUST00000010502.6
Ifi35
interferon-induced protein 35
chr1_+_182409162 0.798 ENSMUST00000117245.1
Trp53bp2
transformation related protein 53 binding protein 2
chr15_-_89149557 0.796 ENSMUST00000088823.3
Mapk11
mitogen-activated protein kinase 11
chr6_-_149101506 0.795 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr2_-_119787504 0.792 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
Rpap1


RNA polymerase II associated protein 1


chr8_-_91313223 0.788 ENSMUST00000047783.7
Rpgrip1l
Rpgrip1-like
chr6_-_86733218 0.787 ENSMUST00000113679.1
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr6_-_117907753 0.786 ENSMUST00000035534.4
4933440N22Rik
RIKEN cDNA 4933440N22 gene
chr12_+_113156403 0.781 ENSMUST00000049271.8
4930427A07Rik
RIKEN cDNA 4930427A07 gene
chr16_-_18811972 0.746 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr17_+_27655572 0.715 ENSMUST00000045896.3
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr2_+_119112793 0.712 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr17_+_27655643 0.711 ENSMUST00000114872.1
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr11_+_101082565 0.711 ENSMUST00000001806.3
ENSMUST00000107308.3
Coasy

Coenzyme A synthase

chr17_+_80290206 0.702 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr9_+_107296843 0.682 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr8_+_31187317 0.679 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr6_-_86733268 0.674 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr8_-_3279606 0.669 ENSMUST00000091291.4
Insr
insulin receptor
chr15_+_99126513 0.665 ENSMUST00000063517.4
Spats2
spermatogenesis associated, serine-rich 2
chr19_+_17394037 0.660 ENSMUST00000025617.3
Rfk
riboflavin kinase
chr3_+_89773562 0.654 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr6_+_58831748 0.642 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr11_+_69991633 0.627 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr10_+_118141787 0.627 ENSMUST00000163238.1
ENSMUST00000020437.5
ENSMUST00000164077.1
ENSMUST00000169817.1
Mdm1



transformed mouse 3T3 cell double minute 1



chr7_-_132852606 0.620 ENSMUST00000120425.1
Mettl10
methyltransferase like 10
chr2_-_26503814 0.609 ENSMUST00000028288.4
Notch1
notch 1
chr17_-_34603675 0.605 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr6_-_77979515 0.586 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr2_-_30093642 0.572 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr3_+_90072641 0.566 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr15_-_82016134 0.562 ENSMUST00000152227.1
Desi1
desumoylating isopeptidase 1
chr11_+_106066055 0.551 ENSMUST00000002048.7
Taco1
translational activator of mitochondrially encoded cytochrome c oxidase I
chr1_+_16665189 0.550 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr17_-_36951636 0.542 ENSMUST00000040402.7
ENSMUST00000174711.1
Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr2_-_172940299 0.536 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr16_-_96127604 0.531 ENSMUST00000133885.1
ENSMUST00000050884.7
Hmgn1

high mobility group nucleosomal binding domain 1

chr16_+_44724271 0.530 ENSMUST00000048788.7
BC027231
cDNA sequence BC027231
chr17_-_57031468 0.529 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr13_+_55152640 0.517 ENSMUST00000005452.5
Fgfr4
fibroblast growth factor receptor 4
chr7_-_28372233 0.516 ENSMUST00000094644.4
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_-_97661668 0.498 ENSMUST00000153115.1
ENSMUST00000142234.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chr16_+_36071624 0.495 ENSMUST00000164916.1
ENSMUST00000163352.1
Ccdc58

coiled-coil domain containing 58

chr17_+_34604262 0.483 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr17_-_36951338 0.473 ENSMUST00000173540.1
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr8_-_70659645 0.457 ENSMUST00000070173.7
Pgpep1
pyroglutamyl-peptidase I
chr19_+_30030589 0.454 ENSMUST00000112552.1
Uhrf2
ubiquitin-like, containing PHD and RING finger domains 2
chr7_-_132852657 0.453 ENSMUST00000033257.8
Mettl10
methyltransferase like 10
chr2_-_30093607 0.453 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr12_+_4917376 0.453 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B
chr4_+_155491353 0.447 ENSMUST00000165335.1
ENSMUST00000105616.3
ENSMUST00000030940.7
Gnb1


guanine nucleotide binding protein (G protein), beta 1


chr10_-_85185003 0.442 ENSMUST00000020227.9
Cry1
cryptochrome 1 (photolyase-like)
chr3_+_135307711 0.441 ENSMUST00000051849.8
Slc9b2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr3_+_69721985 0.438 ENSMUST00000029358.8
Nmd3
NMD3 homolog (S. cerevisiae)
chr7_+_29983948 0.437 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr4_+_135963742 0.431 ENSMUST00000149636.1
ENSMUST00000143304.1
Gale

galactose-4-epimerase, UDP

chr1_+_63273261 0.429 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr10_+_13008442 0.426 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr11_-_120457936 0.415 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr11_+_120491840 0.412 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr17_-_35516780 0.390 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr7_+_4915202 0.388 ENSMUST00000116354.2
Zfp628
zinc finger protein 628
chr1_-_97661950 0.386 ENSMUST00000053033.7
ENSMUST00000149927.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chr9_-_48495321 0.386 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr10_-_75860250 0.379 ENSMUST00000038169.6
Mif
macrophage migration inhibitory factor
chr5_+_107900859 0.371 ENSMUST00000153590.1
Rpl5
ribosomal protein L5
chr5_-_33936301 0.366 ENSMUST00000030993.6
Nelfa
negative elongation factor complex member A, Whsc2
chr6_-_39557830 0.364 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr5_+_107900502 0.358 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr6_-_149188648 0.356 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
Amn1


antagonist of mitotic exit network 1


chr15_+_58872646 0.355 ENSMUST00000036937.7
Trmt12
tRNA methyltranferase 12
chr7_-_42578588 0.354 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr6_-_51469836 0.352 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr7_-_144553657 0.352 ENSMUST00000168134.3
Ppfia1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr6_-_88518760 0.348 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr2_+_144594054 0.348 ENSMUST00000136628.1
Gm561
predicted gene 561
chr5_-_65697856 0.341 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr12_-_81594958 0.337 ENSMUST00000002756.7
ENSMUST00000161598.1
ENSMUST00000161211.1
Med6


mediator of RNA polymerase II transcription, subunit 6 homolog (yeast)


chr12_+_59013379 0.335 ENSMUST00000021379.7
Gemin2
gem (nuclear organelle) associated protein 2
chr5_-_24730635 0.334 ENSMUST00000068693.5
Wdr86
WD repeat domain 86
chr12_+_4817545 0.333 ENSMUST00000046207.7
0610009D07Rik
RIKEN cDNA 0610009D07 gene
chr7_+_118855735 0.328 ENSMUST00000098087.2
ENSMUST00000106547.1
Iqck

IQ motif containing K

chr2_+_157279065 0.322 ENSMUST00000029171.5
Rpn2
ribophorin II
chr11_-_87086752 0.318 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr2_-_9883993 0.313 ENSMUST00000114915.2
9230102O04Rik
RIKEN cDNA 9230102O04 gene
chr19_-_53038534 0.307 ENSMUST00000183274.1
ENSMUST00000182097.1
ENSMUST00000069988.8
Xpnpep1


X-prolyl aminopeptidase (aminopeptidase P) 1, soluble


chr1_+_135818593 0.306 ENSMUST00000038760.8
Lad1
ladinin
chr5_+_147860615 0.302 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chr6_+_83165920 0.301 ENSMUST00000077407.5
ENSMUST00000113913.1
ENSMUST00000130212.1
Dctn1


dynactin 1


chr9_+_108347827 0.294 ENSMUST00000035237.6
Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr10_-_80387642 0.290 ENSMUST00000062946.6
ENSMUST00000105350.1
Mex3d

mex3 homolog D (C. elegans)

chr1_-_125435694 0.285 ENSMUST00000178474.1
ENSMUST00000027579.10
Actr3

ARP3 actin-related protein 3

chr15_-_83149270 0.285 ENSMUST00000129372.1
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr19_-_6941428 0.282 ENSMUST00000025909.4
ENSMUST00000099774.3
Gpr137

G protein-coupled receptor 137

chr2_+_157279026 0.280 ENSMUST00000116380.2
Rpn2
ribophorin II
chr17_-_74294834 0.277 ENSMUST00000078459.6
Memo1
mediator of cell motility 1
chr10_+_128411616 0.267 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr1_+_136415267 0.257 ENSMUST00000027655.6
Ddx59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr13_+_14613242 0.255 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr7_-_114117761 0.250 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr9_+_63602650 0.249 ENSMUST00000041551.7
Aagab
alpha- and gamma-adaptin binding protein
chr1_+_118389058 0.247 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
Clasp1



CLIP associating protein 1



chrX_+_52791179 0.247 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr5_+_10236829 0.237 ENSMUST00000101606.3
Gm10482
predicted gene 10482
chr17_-_15498263 0.235 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr5_-_4104654 0.234 ENSMUST00000001507.4
Cyp51
cytochrome P450, family 51
chr16_+_10835046 0.231 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr5_-_35575046 0.226 ENSMUST00000030980.7
Trmt44
tRNA methyltransferase 44
chr5_-_100416115 0.222 ENSMUST00000182886.1
ENSMUST00000094578.4
Sec31a

Sec31 homolog A (S. cerevisiae)

chr11_+_97703394 0.221 ENSMUST00000103147.4
Psmb3
proteasome (prosome, macropain) subunit, beta type 3
chr1_-_184033998 0.217 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr2_-_3512746 0.216 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr9_+_55209190 0.212 ENSMUST00000146201.1
Fbxo22
F-box protein 22
chr11_-_62457772 0.211 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr8_-_124021008 0.211 ENSMUST00000093039.5
Taf5l
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr1_-_87510306 0.208 ENSMUST00000027477.8
Ngef
neuronal guanine nucleotide exchange factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.8 4.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.6 2.4 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.5 0.5 GO:2000830 vacuolar phosphate transport(GO:0007037) vitamin D3 metabolic process(GO:0070640) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4 1.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 1.7 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.4 1.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 3.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.4 2.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.4 1.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 0.7 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.3 1.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.3 0.9 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.3 1.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 0.9 GO:1903334 positive regulation of protein folding(GO:1903334)
0.3 0.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3 2.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 0.5 GO:0072076 neural fold elevation formation(GO:0021502) nephrogenic mesenchyme development(GO:0072076)
0.3 1.0 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.3 2.5 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.3 3.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 2.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.2 0.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.6 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.2 3.7 GO:0042711 maternal behavior(GO:0042711)
0.2 0.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 0.9 GO:0060242 contact inhibition(GO:0060242)
0.2 0.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 1.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.2 1.1 GO:2001225 peptidyl-serine autophosphorylation(GO:0036289) cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.8 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.7 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.5 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 2.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0061623 glycolytic process from galactose(GO:0061623)
0.1 6.3 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 0.4 GO:0015744 succinate transport(GO:0015744)
0.1 0.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 0.3 GO:0031038 meiotic chromosome movement towards spindle pole(GO:0016344) myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) regulation of bleb assembly(GO:1904170)
0.1 0.4 GO:0002035 brain renin-angiotensin system(GO:0002035) positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.9 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.4 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 3.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 3.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.2 GO:0072179 nephric duct formation(GO:0072179)
0.1 0.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.7 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 1.3 GO:0006999 nuclear pore organization(GO:0006999)
0.1 1.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 1.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081) positive regulation of microtubule nucleation(GO:0090063)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.8 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.5 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0048793 pronephros development(GO:0048793)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 1.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 2.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.8 GO:0043584 nose development(GO:0043584)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.4 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:2000189 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.4 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.2 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 1.1 GO:0001947 heart looping(GO:0001947)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 1.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 1.5 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0097494 regulation of vesicle size(GO:0097494)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.5 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0005883 neurofilament(GO:0005883)
0.4 1.6 GO:0008537 proteasome activator complex(GO:0008537)
0.3 0.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 3.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 1.0 GO:0031983 vesicle lumen(GO:0031983)
0.2 0.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 4.5 GO:0000145 exocyst(GO:0000145)
0.2 0.7 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.1 GO:0097361 CIA complex(GO:0097361)
0.1 2.4 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0070847 core mediator complex(GO:0070847)
0.1 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 3.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.6 GO:0016234 inclusion body(GO:0016234)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 1.3 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 1.2 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.3 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 2.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 0.9 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.3 2.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 2.0 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 1.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 5.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.7 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 0.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.4 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.7 GO:0000150 recombinase activity(GO:0000150)
0.1 9.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 4.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.0 GO:0000149 SNARE binding(GO:0000149)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 8.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 0.8 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 4.1 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 2.7 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 2.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.4 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.9 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.7 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 2.5 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 1.0 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.1 1.1 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.9 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.7 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 1.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.3 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 2.0 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.0 0.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.2 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation