Motif ID: Cpeb1

Z-value: 2.057


Transcription factors associated with Cpeb1:

Gene SymbolEntrez IDGene Name
Cpeb1 ENSMUSG00000025586.10 Cpeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cpeb1mm10_v2_chr7_-_81454751_814547640.038.6e-01Click!


Activity profile for motif Cpeb1.

activity profile for motif Cpeb1


Sorted Z-values histogram for motif Cpeb1

Sorted Z-values for motif Cpeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cpeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 27.761 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr3_+_5218546 23.152 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_-_63851251 21.329 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chr3_+_5218516 21.279 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr1_+_6730051 20.338 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr2_-_51149100 20.007 ENSMUST00000154545.1
ENSMUST00000017288.2
 Rnd3

Rho family GTPase 3

chr2_-_18048784 19.517 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr1_-_138842429 18.675 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr1_+_6734827 16.096 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr3_+_5218589 14.577 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr11_-_99024179 14.522 ENSMUST00000068031.7
 Top2a
topoisomerase (DNA) II alpha
chr1_+_6730135 14.141 ENSMUST00000155921.1
 St18
suppression of tumorigenicity 18
chr2_-_137116624 13.585 ENSMUST00000028735.7
 Jag1
jagged 1
chr2_-_18048347 13.314 ENSMUST00000066885.5
 Skida1
SKI/DACH domain containing 1
chr3_+_87948666 13.252 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_-_103853199 11.572 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr14_-_48667508 11.486 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr17_+_43953191 10.399 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2
chr4_+_11704439 10.084 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr12_-_54986328 9.443 ENSMUST00000038926.6
 Baz1a
bromodomain adjacent to zinc finger domain 1A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 172 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.2 50.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.5 21.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
2.6 20.6 GO:0048625 myoblast fate commitment(GO:0048625)
1.3 19.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
3.7 18.7 GO:0035262 gonad morphogenesis(GO:0035262)
3.7 14.6 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.3 14.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 14.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
3.6 14.5 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1 13.7 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
2.7 13.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.8 12.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.4 12.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.9 11.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
2.3 11.6 GO:0015671 oxygen transport(GO:0015671)
0.7 10.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.1 10.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
3.1 9.3 GO:0060023 soft palate development(GO:0060023)
1.7 8.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 8.5 GO:0060009 Sertoli cell development(GO:0060009)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 54.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 25.1 GO:0005912 adherens junction(GO:0005912)
2.4 22.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
4.6 18.5 GO:0008623 CHRAC(GO:0008623)
0.2 17.2 GO:0005814 centriole(GO:0005814)
0.0 15.9 GO:0016607 nuclear speck(GO:0016607)
0.1 14.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.5 13.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 10.1 GO:0051233 spindle midzone(GO:0051233)
0.1 9.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 7.9 GO:1990391 DNA repair complex(GO:1990391)
0.1 7.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.5 7.0 GO:0042788 polysomal ribosome(GO:0042788)
0.0 6.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.6 6.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.4 5.8 GO:0045098 type III intermediate filament(GO:0045098)
0.9 5.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.7 5.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 5.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 5.2 GO:0000775 chromosome, centromeric region(GO:0000775)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 124 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 62.5 GO:0001047 core promoter binding(GO:0001047)
0.1 54.3 GO:0008270 zinc ion binding(GO:0008270)
1.1 21.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 20.5 GO:0019904 protein domain specific binding(GO:0019904)
0.9 19.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 19.2 GO:0003924 GTPase activity(GO:0003924)
0.1 18.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 15.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
3.6 14.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.4 13.9 GO:0005112 Notch binding(GO:0005112)
2.2 13.3 GO:0019841 retinol binding(GO:0019841)
0.1 13.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.8 12.7 GO:0003680 AT DNA binding(GO:0003680)
0.3 11.7 GO:0032452 histone demethylase activity(GO:0032452)
2.3 11.6 GO:0005344 oxygen transporter activity(GO:0005344)
1.6 11.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.7 10.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.9 9.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 9.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
1.0 8.7 GO:0043237 laminin-1 binding(GO:0043237)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 19.9 PID_AP1_PATHWAY AP-1 transcription factor network
0.4 14.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 13.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 13.0 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 12.7 PID_CDC42_PATHWAY CDC42 signaling events
0.3 11.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.2 11.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 11.0 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 10.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 8.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 6.8 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.3 5.9 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 5.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 5.4 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.2 5.2 NABA_COLLAGENS Genes encoding collagen proteins
0.2 5.0 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 4.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 4.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.5 PID_PLK1_PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 13.6 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.9 12.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 11.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 9.9 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 9.1 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.1 8.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 7.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 7.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 7.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 5.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
1.9 5.7 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 5.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.3 5.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 5.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.3 4.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 4.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.1 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 4.1 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 4.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation