Motif ID: Creb1

Z-value: 1.418


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_645328150.642.0e-05Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_4907705 7.589 ENSMUST00000020962.5
Ubxn2a
UBX domain protein 2A
chr19_+_6084983 5.826 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr12_-_4907229 5.151 ENSMUST00000142867.1
Ubxn2a
UBX domain protein 2A
chr6_+_113531675 4.164 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr11_+_43528759 3.917 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr9_-_66919646 3.849 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr13_-_29984219 3.818 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr3_+_135212557 3.793 ENSMUST00000062893.7
Cenpe
centromere protein E
chr2_+_119047116 3.689 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr9_+_122951051 3.642 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr7_-_47008397 3.423 ENSMUST00000061639.7
Spty2d1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr2_+_156840966 3.381 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr8_+_57511833 3.233 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr12_-_98901478 3.083 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr7_-_137314394 3.044 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr2_+_119047129 3.011 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr7_-_38107490 2.469 ENSMUST00000108023.3
Ccne1
cyclin E1
chr12_+_73286868 2.466 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr3_+_127553462 2.313 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr17_-_56476462 2.289 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr13_+_108214389 2.254 ENSMUST00000022207.8
Elovl7
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr5_-_125179155 2.246 ENSMUST00000111393.1
ENSMUST00000111394.1
ENSMUST00000111402.2
ENSMUST00000111398.1
Ncor2



nuclear receptor co-repressor 2



chr15_-_76710486 2.195 ENSMUST00000036852.7
Recql4
RecQ protein-like 4
chr1_-_58973421 2.170 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr11_+_114765363 2.084 ENSMUST00000138804.1
ENSMUST00000084368.5
Kif19a

kinesin family member 19A

chr9_+_118506226 2.074 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr10_-_31609184 2.068 ENSMUST00000081989.6
Rnf217
ring finger protein 217
chr5_+_48372363 2.051 ENSMUST00000030968.2
Pacrgl
PARK2 co-regulated-like
chr5_+_53590215 2.016 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr7_-_118533298 1.984 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr8_+_40511769 1.886 ENSMUST00000098817.2
Vps37a
vacuolar protein sorting 37A (yeast)
chr10_+_121033960 1.877 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr2_-_18048347 1.868 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr15_-_94589870 1.848 ENSMUST00000023087.6
ENSMUST00000152590.1
Twf1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr10_+_77622275 1.829 ENSMUST00000174510.1
ENSMUST00000172813.1
Ube2g2

ubiquitin-conjugating enzyme E2G 2

chr5_-_125179053 1.826 ENSMUST00000086083.4
Ncor2
nuclear receptor co-repressor 2
chr4_+_115737738 1.797 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr4_+_100776664 1.759 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr4_-_58553553 1.758 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr10_+_77622363 1.739 ENSMUST00000172772.1
Ube2g2
ubiquitin-conjugating enzyme E2G 2
chr4_+_115737754 1.713 ENSMUST00000106522.2
Efcab14
EF-hand calcium binding domain 14
chr11_-_86807624 1.703 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr2_+_144556229 1.688 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b


SEC23B (S. cerevisiae)


chr4_-_19708922 1.687 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr5_+_53590453 1.682 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr6_+_65042575 1.662 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_-_101083653 1.658 ENSMUST00000048305.8
ENSMUST00000163095.1
Smek1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

chr2_-_127788854 1.655 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr15_-_96460838 1.644 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chrX_-_20962005 1.638 ENSMUST00000123836.1
Uxt
ubiquitously expressed transcript
chr12_+_116281180 1.632 ENSMUST00000100986.2
Esyt2
extended synaptotagmin-like protein 2
chr7_-_79715669 1.610 ENSMUST00000184137.1
ENSMUST00000183846.1
Kif7

kinesin family member 7

chr16_+_43889896 1.602 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr19_-_4163285 1.581 ENSMUST00000118483.1
ENSMUST00000025749.7
Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

chr17_+_15010266 1.553 ENSMUST00000097395.3
Gm3435
predicted gene 3435
chr4_-_58553311 1.547 ENSMUST00000107571.1
ENSMUST00000055018.4
Lpar1

lysophosphatidic acid receptor 1

chr5_-_124032214 1.537 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr18_+_11657349 1.532 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chrX_-_56598069 1.529 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr7_-_116443439 1.512 ENSMUST00000170430.1
Pik3c2a
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
chr10_-_19015347 1.499 ENSMUST00000019997.4
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr7_-_35056467 1.499 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr1_+_132298606 1.499 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr2_+_144556306 1.493 ENSMUST00000155876.1
ENSMUST00000149697.1
Sec23b

SEC23B (S. cerevisiae)

chr16_+_43889936 1.472 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr14_-_55745647 1.464 ENSMUST00000002403.8
Dhrs1
dehydrogenase/reductase (SDR family) member 1
chr10_+_82954344 1.450 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr16_+_43889800 1.407 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr2_+_27886416 1.393 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr11_+_116918844 1.384 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr9_+_30427329 1.380 ENSMUST00000164099.1
Snx19
sorting nexin 19
chr10_-_117376922 1.364 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr12_+_71016658 1.337 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr9_-_96364299 1.328 ENSMUST00000034983.5
Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr15_+_66577536 1.315 ENSMUST00000048188.8
Phf20l1
PHD finger protein 20-like 1
chr15_-_89355655 1.276 ENSMUST00000023283.5
Lmf2
lipase maturation factor 2
chr12_+_52097737 1.268 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr5_+_150522599 1.266 ENSMUST00000044620.7
Brca2
breast cancer 2
chr11_+_93996082 1.253 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr17_-_56290499 1.240 ENSMUST00000019726.6
Plin3
perilipin 3
chr3_-_101924378 1.233 ENSMUST00000106928.3
Slc22a15
solute carrier family 22 (organic anion/cation transporter), member 15
chr9_-_44234014 1.219 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr17_-_34627148 1.218 ENSMUST00000171376.1
ENSMUST00000169287.1
Ppt2

palmitoyl-protein thioesterase 2

chr7_-_46795661 1.217 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr1_-_106796687 1.182 ENSMUST00000094646.5
Vps4b
vacuolar protein sorting 4b (yeast)
chr10_+_62920648 1.174 ENSMUST00000144459.1
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr17_+_15041641 1.161 ENSMUST00000097393.3
Ermard
ER membrane associated RNA degradation
chr3_+_108284089 1.157 ENSMUST00000102632.4
Sort1
sortilin 1
chr8_+_60993189 1.156 ENSMUST00000034065.7
ENSMUST00000120689.1
Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

chr17_+_29660595 1.137 ENSMUST00000024816.6
Cmtr1
cap methyltransferase 1
chr1_+_150392794 1.132 ENSMUST00000124973.2
Tpr
translocated promoter region
chr7_+_3629985 1.130 ENSMUST00000008517.6
ENSMUST00000179769.1
Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)

chr16_+_22009471 1.115 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr14_+_31495065 1.105 ENSMUST00000022446.5
Eaf1
ELL associated factor 1
chrX_+_71816758 1.099 ENSMUST00000114576.2
ENSMUST00000114575.3
Vma21

VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)

chr11_-_97766508 1.082 ENSMUST00000107579.1
ENSMUST00000018685.2
Cwc25

CWC25 spliceosome-associated protein homolog (S. cerevisiae)

chr10_+_62920630 1.081 ENSMUST00000044977.3
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr3_+_138143799 1.062 ENSMUST00000159622.1
Trmt10a
tRNA methyltransferase 10A
chr16_+_15637844 1.059 ENSMUST00000023352.8
Prkdc
protein kinase, DNA activated, catalytic polypeptide
chr2_+_116067213 1.051 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr4_-_138913915 1.050 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr1_+_150393250 1.046 ENSMUST00000119161.2
Tpr
translocated promoter region
chr2_+_29346803 1.014 ENSMUST00000028139.4
ENSMUST00000113830.4
Med27

mediator complex subunit 27

chr17_-_27907706 1.007 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_+_105157339 1.007 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr6_+_41605482 1.000 ENSMUST00000114732.2
Ephb6
Eph receptor B6
chr7_-_55962424 0.996 ENSMUST00000126604.1
ENSMUST00000117812.1
ENSMUST00000119201.1
Nipa2


non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)


chr19_-_10949238 0.990 ENSMUST00000025639.6
Ccdc86
coiled-coil domain containing 86
chr5_-_44226601 0.979 ENSMUST00000055128.7
Tapt1
transmembrane anterior posterior transformation 1
chr5_-_65335597 0.975 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1


replication factor C (activator 1) 1


chr9_+_59291565 0.966 ENSMUST00000026266.7
Adpgk
ADP-dependent glucokinase
chr4_-_133753611 0.966 ENSMUST00000145664.2
ENSMUST00000105897.3
Arid1a

AT rich interactive domain 1A (SWI-like)

chr10_+_58446845 0.965 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr10_+_94688739 0.965 ENSMUST00000020212.4
Ccdc41
coiled-coil domain containing 41
chr16_+_38562806 0.959 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr7_-_46795881 0.954 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr17_-_34627365 0.949 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
Ppt2




palmitoyl-protein thioesterase 2




chr3_+_138143429 0.949 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr8_-_111027752 0.936 ENSMUST00000040241.8
Ddx19b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
chr5_-_135394499 0.896 ENSMUST00000065638.4
ENSMUST00000111171.2
Pom121

nuclear pore membrane protein 121

chr3_+_138143846 0.894 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr15_-_59374149 0.888 ENSMUST00000022976.4
E430025E21Rik
RIKEN cDNA E430025E21 gene
chr2_+_71786923 0.888 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr6_-_86733268 0.880 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr14_+_54883377 0.877 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chr5_-_31179901 0.877 ENSMUST00000101411.2
ENSMUST00000140793.1
Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr14_+_25459206 0.864 ENSMUST00000162645.1
Zmiz1
zinc finger, MIZ-type containing 1
chr7_-_55962466 0.863 ENSMUST00000032635.7
ENSMUST00000152649.1
Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr14_+_8214135 0.862 ENSMUST00000022272.6
Kctd6
potassium channel tetramerisation domain containing 6
chr13_-_53377355 0.854 ENSMUST00000021920.6
Sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr13_-_100104064 0.841 ENSMUST00000038104.5
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr7_-_30664986 0.825 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr10_-_127041513 0.820 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr6_-_4086914 0.815 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr14_+_31251454 0.814 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chrX_-_137038265 0.802 ENSMUST00000113070.2
ENSMUST00000113069.2
Slc25a53

solute carrier family 25, member 53

chr9_+_35211155 0.798 ENSMUST00000034541.5
Srpr
signal recognition particle receptor ('docking protein')
chr11_+_74649462 0.781 ENSMUST00000092915.5
ENSMUST00000117818.1
Cluh

clustered mitochondria (cluA/CLU1) homolog

chr18_-_35498856 0.775 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr17_+_29660710 0.774 ENSMUST00000130423.1
Cmtr1
cap methyltransferase 1
chr14_+_30654360 0.773 ENSMUST00000064230.7
Rft1
RFT1 homolog (S. cerevisiae)
chr3_+_138143483 0.772 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr5_-_31180110 0.768 ENSMUST00000043161.6
ENSMUST00000088010.5
Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr12_-_56345862 0.762 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr9_+_96119362 0.758 ENSMUST00000085217.5
ENSMUST00000122383.1
Gk5

glycerol kinase 5 (putative)

chrX_-_93632113 0.753 ENSMUST00000006856.2
Pola1
polymerase (DNA directed), alpha 1
chr2_+_163017354 0.750 ENSMUST00000018002.6
ENSMUST00000150396.1
Ift52

intraflagellar transport 52

chr14_+_55745678 0.750 ENSMUST00000019441.8
Nop9
NOP9 nucleolar protein
chr5_-_65335564 0.741 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr10_+_36974558 0.735 ENSMUST00000105510.1
Hdac2
histone deacetylase 2
chr10_+_82629803 0.733 ENSMUST00000092266.4
ENSMUST00000151390.1
Tdg

thymine DNA glycosylase

chr10_-_30618436 0.731 ENSMUST00000161074.1
Hint3
histidine triad nucleotide binding protein 3
chr14_+_63860290 0.725 ENSMUST00000022528.4
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr4_+_98923845 0.719 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chrX_-_74023745 0.718 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1

interleukin-1 receptor-associated kinase 1

chr4_-_58553184 0.708 ENSMUST00000145361.1
Lpar1
lysophosphatidic acid receptor 1
chr1_-_106796609 0.706 ENSMUST00000112736.1
Vps4b
vacuolar protein sorting 4b (yeast)
chr3_+_138143888 0.703 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr16_-_43889669 0.702 ENSMUST00000023387.7
Qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr5_+_24100578 0.702 ENSMUST00000030841.5
ENSMUST00000163409.1
Klhl7

kelch-like 7

chrX_-_74023908 0.701 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
Irak1




interleukin-1 receptor-associated kinase 1




chr8_+_117157972 0.696 ENSMUST00000064488.4
ENSMUST00000162997.1
Gan

giant axonal neuropathy

chr16_+_38562821 0.679 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr2_-_38712195 0.672 ENSMUST00000112883.1
Nr5a1
nuclear receptor subfamily 5, group A, member 1
chr11_-_70700105 0.666 ENSMUST00000108543.3
ENSMUST00000108542.1
ENSMUST00000108541.2
ENSMUST00000126114.2
ENSMUST00000073625.1
Inca1




inhibitor of CDK, cyclin A1 interacting protein 1




chr17_+_14978864 0.666 ENSMUST00000061688.9
9030025P20Rik
RIKEN cDNA 9030025P20 gene
chr19_+_5041337 0.661 ENSMUST00000116567.2
Brms1
breast cancer metastasis-suppressor 1
chr10_+_57486354 0.638 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr13_-_58215615 0.634 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1

ubiquilin 1

chr4_+_98923810 0.633 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr9_-_53248106 0.633 ENSMUST00000065630.6
Ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr12_+_86678685 0.631 ENSMUST00000021681.3
Vash1
vasohibin 1
chr5_-_92505518 0.630 ENSMUST00000031377.7
Scarb2
scavenger receptor class B, member 2
chr5_+_67260794 0.624 ENSMUST00000161369.1
Tmem33
transmembrane protein 33
chr13_+_96542727 0.619 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr8_-_47289394 0.593 ENSMUST00000079195.5
Stox2
storkhead box 2
chr10_+_36974536 0.593 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr10_+_44268328 0.592 ENSMUST00000039286.4
Atg5
autophagy related 5
chr4_-_149307506 0.590 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr9_+_64179289 0.582 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr5_+_67260696 0.582 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33

transmembrane protein 33

chr4_+_45184815 0.553 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr6_+_114643094 0.552 ENSMUST00000032457.10
Atg7
autophagy related 7
chr17_+_46496753 0.547 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_-_24961545 0.539 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr10_+_59879556 0.539 ENSMUST00000147914.1
ENSMUST00000146590.1
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr5_+_35583018 0.537 ENSMUST00000068947.7
ENSMUST00000114237.1
ENSMUST00000156125.1
ENSMUST00000068563.5
Acox3



acyl-Coenzyme A oxidase 3, pristanoyl



chr9_-_96478596 0.536 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr12_-_73286698 0.529 ENSMUST00000116420.2
Trmt5
TRM5 tRNA methyltransferase 5
chr5_+_24164963 0.521 ENSMUST00000049887.6
Nupl2
nucleoporin like 2
chr13_+_51651697 0.520 ENSMUST00000040117.8
ENSMUST00000110044.1
Secisbp2

SECIS binding protein 2

chr5_-_35575046 0.514 ENSMUST00000030980.7
Trmt44
tRNA methyltransferase 44
chr16_+_32247221 0.513 ENSMUST00000178573.1
ENSMUST00000023474.3
Wdr53

WD repeat domain 53

chr13_-_38635036 0.510 ENSMUST00000035899.6
Bloc1s5
biogenesis of organelles complex-1, subunit 5, muted
chr11_+_52396414 0.505 ENSMUST00000109057.1
ENSMUST00000036952.4
9530068E07Rik

RIKEN cDNA 9530068E07 gene

chr10_+_59879617 0.499 ENSMUST00000142819.1
ENSMUST00000020309.6
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr15_-_75841907 0.497 ENSMUST00000100538.2
Zc3h3
zinc finger CCCH type containing 3
chr10_-_117376955 0.495 ENSMUST00000069168.6
ENSMUST00000176686.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr1_+_127774164 0.466 ENSMUST00000027587.8
ENSMUST00000112570.1
Ccnt2

cyclin T2

chr10_-_30200492 0.459 ENSMUST00000099985.4
Cenpw
centromere protein W

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.4 5.6 GO:0010847 regulation of chromatin assembly(GO:0010847)
1.2 3.7 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
1.1 12.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
1.0 4.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
1.0 4.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.9 1.9 GO:1903722 regulation of centriole elongation(GO:1903722)
0.8 5.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.6 1.9 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.6 0.6 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.6 3.8 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.6 1.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.5 3.8 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.5 3.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.5 1.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.5 1.5 GO:0071579 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.5 3.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.5 2.0 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.5 1.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 2.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.4 1.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.4 2.2 GO:0045875 DNA strand renaturation(GO:0000733) negative regulation of sister chromatid cohesion(GO:0045875)
0.4 0.7 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.4 3.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 1.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.3 1.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.3 2.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.3 1.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.3 GO:0051311 meiotic metaphase plate congression(GO:0051311) attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.3 1.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 0.9 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.3 0.6 GO:0035973 aggrephagy(GO:0035973)
0.3 0.9 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.3 1.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 1.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 1.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 1.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.7 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 2.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 2.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 1.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 1.5 GO:0045078 enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 1.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 2.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.8 GO:0006272 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.2 3.4 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.5 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.2 5.6 GO:0030488 tRNA methylation(GO:0030488)
0.2 0.5 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.2 2.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.7 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.2 1.2 GO:0051004 plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004)
0.2 3.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 0.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.8 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.9 GO:0035878 nail development(GO:0035878)
0.1 0.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 1.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.8 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.8 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.4 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 1.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.5 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.9 GO:0000012 single strand break repair(GO:0000012)
0.1 2.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 1.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 2.5 GO:0007129 synapsis(GO:0007129)
0.1 0.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:0048296 negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.1 0.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) positive regulation of maintenance of sister chromatid cohesion(GO:0034093) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 2.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 1.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.8 GO:0034204 lipid translocation(GO:0034204)
0.0 0.2 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.5 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.6 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0 1.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 1.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 2.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 3.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 2.4 GO:0007596 blood coagulation(GO:0007596)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.4 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 1.0 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.0 GO:0032364 oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.8 GO:0008278 cohesin complex(GO:0008278)
0.7 3.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5 2.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.5 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.4 2.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 3.1 GO:0000813 ESCRT I complex(GO:0000813)
0.3 0.9 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3 3.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)
0.3 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 1.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 3.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 2.5 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.2 13.1 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.9 GO:0042382 paraspeckles(GO:0042382)
0.2 3.8 GO:0051286 cell tip(GO:0051286)
0.2 0.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.9 GO:0090543 Flemming body(GO:0090543)
0.2 1.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2 1.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 0.6 GO:0043202 lysosomal lumen(GO:0043202)
0.2 0.5 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.2 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 7.7 GO:0005871 kinesin complex(GO:0005871)
0.1 0.4 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 1.2 GO:0016600 flotillin complex(GO:0016600)
0.1 2.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.1 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.5 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.3 GO:0000800 lateral element(GO:0000800)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.3 GO:0032021 NELF complex(GO:0032021)
0.1 2.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 7.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 1.2 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.1 1.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.0 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 5.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 3.3 GO:0005643 nuclear pore(GO:0005643)
0.0 2.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 4.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 3.4 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.2 GO:0000776 kinetochore(GO:0000776)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.7 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0043515 kinetochore binding(GO:0043515)
0.6 4.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.6 4.0 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.5 3.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 1.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 3.8 GO:0030911 TPR domain binding(GO:0030911)
0.5 1.9 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.5 12.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 2.2 GO:0000405 bubble DNA binding(GO:0000405)
0.4 1.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 1.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 1.3 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.3 1.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 0.9 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.3 0.8 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 1.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 2.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 1.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 2.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 1.5 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.2 0.7 GO:0004844 mismatch base pair DNA N-glycosylase activity(GO:0000700) uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 0.5 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 0.9 GO:0097001 ceramide binding(GO:0097001)
0.1 5.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.8 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 1.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 3.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 5.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 3.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.3 GO:0035473 lipase binding(GO:0035473)
0.1 1.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 4.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 3.6 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 0.8 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 1.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.9 GO:0051400 BH domain binding(GO:0051400)
0.1 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 3.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 2.5 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.4 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.8 GO:0005319 lipid transporter activity(GO:0005319)
0.0 5.4 GO:0003682 chromatin binding(GO:0003682)
0.0 1.5 GO:0004386 helicase activity(GO:0004386)
0.0 1.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.9 GO:0008017 microtubule binding(GO:0008017)
0.0 5.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.2 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.8 GO:0042623 ATPase activity, coupled(GO:0042623)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.2 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 7.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 4.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 6.4 PID_E2F_PATHWAY E2F transcription factor network
0.1 3.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 1.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.7 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 3.8 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.5 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 4.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.7 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.5 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 1.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.9 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 3.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 3.8 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 7.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 1.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 3.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 3.2 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 3.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 1.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 2.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.6 REACTOME_KINESINS Genes involved in Kinesins
0.1 6.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 2.1 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.0 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.6 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.9 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.1 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.6 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.7 REACTOME_SIGNALING_BY_ERBB4 Genes involved in Signaling by ERBB4
0.0 0.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 3.3 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 4.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.4 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.1 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Assembly of the pre-replicative complex