Motif ID: Creb3l2

Z-value: 0.498


Transcription factors associated with Creb3l2:

Gene SymbolEntrez IDGene Name
Creb3l2 ENSMUSG00000038648.5 Creb3l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_37442154-0.076.9e-01Click!


Activity profile for motif Creb3l2.

activity profile for motif Creb3l2


Sorted Z-values histogram for motif Creb3l2

Sorted Z-values for motif Creb3l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3l2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_148591482 2.796 ENSMUST00000006611.8
Srm
spermidine synthase
chr13_-_92131494 2.177 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr6_-_22356068 1.982 ENSMUST00000163963.1
ENSMUST00000165576.1
Fam3c

family with sequence similarity 3, member C

chr3_+_123267445 1.968 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chrX_+_8271133 1.856 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr6_-_22356176 1.840 ENSMUST00000081288.7
Fam3c
family with sequence similarity 3, member C
chr19_-_6840590 1.510 ENSMUST00000170516.2
ENSMUST00000025903.5
Rps6ka4

ribosomal protein S6 kinase, polypeptide 4

chr6_-_8778439 1.468 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1


chr5_+_107331157 1.424 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr5_-_30945393 1.399 ENSMUST00000031051.6
Cgref1
cell growth regulator with EF hand domain 1
chr6_-_8778106 1.336 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr11_-_55033398 1.221 ENSMUST00000108883.3
ENSMUST00000102727.2
Anxa6

annexin A6

chr18_+_75018709 1.209 ENSMUST00000039608.7
Dym
dymeclin
chr9_+_89909775 1.189 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr6_-_13871459 1.081 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr15_-_102136225 1.017 ENSMUST00000154032.1
Spryd3
SPRY domain containing 3
chr6_-_13871477 1.011 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr4_-_45084538 0.971 ENSMUST00000052236.6
Fbxo10
F-box protein 10
chr15_-_75678732 0.948 ENSMUST00000000958.8
Top1mt
DNA topoisomerase 1, mitochondrial
chr11_+_100415697 0.943 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr3_-_20155069 0.917 ENSMUST00000184552.1
ENSMUST00000178328.1
Gyg

glycogenin

chrX_+_153139941 0.895 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr5_-_35679416 0.879 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chr3_+_104638658 0.837 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr11_+_100415722 0.836 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chr6_+_56832059 0.821 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9
chr16_-_4880284 0.808 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr18_+_65800543 0.793 ENSMUST00000025394.6
ENSMUST00000153193.1
Sec11c

SEC11 homolog C (S. cerevisiae)

chr10_-_20725023 0.769 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr11_-_120643643 0.755 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr11_-_96075581 0.700 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr11_-_96075655 0.662 ENSMUST00000090541.5
Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chrX_-_73786888 0.645 ENSMUST00000052761.8
Idh3g
isocitrate dehydrogenase 3 (NAD+), gamma
chr17_+_87107621 0.642 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr3_-_89773221 0.630 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr11_-_97500340 0.601 ENSMUST00000056955.1
4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr2_+_150786735 0.592 ENSMUST00000045441.7
Pygb
brain glycogen phosphorylase
chr18_+_67464849 0.568 ENSMUST00000025411.7
Slmo1
slowmo homolog 1 (Drosophila)
chr2_-_164833438 0.565 ENSMUST00000042775.4
Neurl2
neuralized-like 2 (Drosophila)
chr13_-_90089513 0.563 ENSMUST00000160232.1
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr8_-_105255100 0.558 ENSMUST00000093217.2
ENSMUST00000161745.2
ENSMUST00000136822.2
B3gnt9


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9


chr10_+_78574492 0.555 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr14_-_70443219 0.551 ENSMUST00000180358.1
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr1_+_75142775 0.549 ENSMUST00000097694.4
Fam134a
family with sequence similarity 134, member A
chr4_-_148038769 0.540 ENSMUST00000030879.5
ENSMUST00000137724.1
Clcn6

chloride channel 6

chr4_-_149774238 0.518 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr4_-_108406676 0.517 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr12_+_69241832 0.517 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr8_+_14911663 0.513 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
Arhgef10


Rho guanine nucleotide exchange factor (GEF) 10


chr12_-_84450944 0.511 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr7_-_127260677 0.509 ENSMUST00000035276.4
Dctpp1
dCTP pyrophosphatase 1
chr5_-_135251209 0.492 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr2_-_35979624 0.491 ENSMUST00000028248.4
ENSMUST00000112976.2
Ttll11

tubulin tyrosine ligase-like family, member 11

chr13_-_24206281 0.477 ENSMUST00000123076.1
Lrrc16a
leucine rich repeat containing 16A
chr8_-_124663368 0.472 ENSMUST00000034464.6
2310022B05Rik
RIKEN cDNA 2310022B05 gene
chr10_+_61648552 0.469 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr2_-_130424242 0.460 ENSMUST00000089581.4
Pced1a
PC-esterase domain containing 1A
chrX_+_163908982 0.440 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_-_16874845 0.426 ENSMUST00000181501.1
9330104G04Rik
RIKEN cDNA 9330104G04 gene
chr1_+_63176818 0.425 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr13_-_90089556 0.419 ENSMUST00000022115.7
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr7_-_25250720 0.416 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr19_+_8819401 0.412 ENSMUST00000096753.3
Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr16_-_30550560 0.387 ENSMUST00000140402.1
Tmem44
transmembrane protein 44
chr2_-_32694120 0.373 ENSMUST00000028148.4
Fpgs
folylpolyglutamyl synthetase
chr19_+_46056539 0.360 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr4_+_155993305 0.352 ENSMUST00000105578.1
Sdf4
stromal cell derived factor 4
chr17_+_45563928 0.347 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chrX_+_7822289 0.332 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr11_-_120572822 0.329 ENSMUST00000168360.1
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr13_-_90089060 0.326 ENSMUST00000161396.1
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr11_+_5099406 0.318 ENSMUST00000134267.1
ENSMUST00000036320.5
ENSMUST00000150632.1
Rhbdd3


rhomboid domain containing 3


chr11_+_69935796 0.317 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr17_+_71183545 0.314 ENSMUST00000156570.1
Lpin2
lipin 2
chr3_+_144570409 0.289 ENSMUST00000082437.3
Sep15
selenoprotein
chr7_-_105640308 0.286 ENSMUST00000133519.1
ENSMUST00000084782.2
ENSMUST00000131446.1
Arfip2


ADP-ribosylation factor interacting protein 2


chr7_+_30169861 0.278 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr15_-_97767798 0.265 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr15_+_79516396 0.263 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr11_+_94653767 0.261 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr6_+_87887814 0.245 ENSMUST00000113607.3
ENSMUST00000049966.5
Copg1

coatomer protein complex, subunit gamma 1

chr13_+_73330982 0.243 ENSMUST00000022098.8
Mrpl36
mitochondrial ribosomal protein L36
chr15_-_97767644 0.238 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr11_+_3649494 0.238 ENSMUST00000093389.2
Morc2a
microrchidia 2A
chr10_-_81060134 0.237 ENSMUST00000005067.5
Sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr8_-_94601720 0.235 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr5_-_45857473 0.235 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr18_-_60848911 0.220 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr4_-_119422355 0.207 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr6_+_87042838 0.200 ENSMUST00000113658.1
ENSMUST00000113657.1
ENSMUST00000113655.1
ENSMUST00000032057.7
Gfpt1



glutamine fructose-6-phosphate transaminase 1



chr15_-_102510681 0.187 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr2_+_130274424 0.185 ENSMUST00000103198.4
Nop56
NOP56 ribonucleoprotein
chr2_+_132846638 0.179 ENSMUST00000028835.6
ENSMUST00000110122.3
Crls1

cardiolipin synthase 1

chr18_-_40219324 0.174 ENSMUST00000025364.4
Yipf5
Yip1 domain family, member 5
chr11_-_97782409 0.173 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr5_+_118560719 0.172 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr17_+_35424842 0.165 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr11_-_97782377 0.164 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr12_+_84451485 0.159 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr18_+_75367529 0.154 ENSMUST00000026999.3
Smad7
SMAD family member 7
chr13_-_55321928 0.150 ENSMUST00000035242.7
Rab24
RAB24, member RAS oncogene family
chr17_-_26939464 0.140 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr5_-_137610626 0.134 ENSMUST00000142675.1
Pcolce
procollagen C-endopeptidase enhancer protein
chr7_+_97696634 0.133 ENSMUST00000026506.4
Clns1a
chloride channel, nucleotide-sensitive, 1A
chr1_+_87326997 0.122 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr16_+_20733104 0.121 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr11_+_44518959 0.121 ENSMUST00000019333.3
Rnf145
ring finger protein 145
chr3_-_27710413 0.118 ENSMUST00000046157.4
Fndc3b
fibronectin type III domain containing 3B
chr10_+_61680302 0.112 ENSMUST00000020285.8
Sar1a
SAR1 gene homolog A (S. cerevisiae)
chr19_+_46573362 0.109 ENSMUST00000026011.6
Sfxn2
sideroflexin 2
chr9_-_115310421 0.109 ENSMUST00000035010.8
Stt3b
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr7_-_30169701 0.104 ENSMUST00000062181.7
Zfp146
zinc finger protein 146
chr10_+_4266323 0.104 ENSMUST00000045730.5
Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr14_-_55643720 0.104 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr13_+_55321991 0.099 ENSMUST00000021942.6
Prelid1
PRELI domain containing 1
chr2_+_130424321 0.096 ENSMUST00000128994.1
ENSMUST00000028900.9
Vps16

vacuolar protein sorting 16 (yeast)

chr5_+_129941949 0.089 ENSMUST00000051758.7
ENSMUST00000073945.4
Vkorc1l1

vitamin K epoxide reductase complex, subunit 1-like 1

chr14_-_55643251 0.088 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr2_+_70661556 0.074 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
Gorasp2



golgi reassembly stacking protein 2



chr11_+_5099608 0.072 ENSMUST00000139742.1
Rhbdd3
rhomboid domain containing 3
chr1_+_87327008 0.070 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr12_+_112588753 0.067 ENSMUST00000101029.2
Inf2
inverted formin, FH2 and WH2 domain containing
chr6_+_127453667 0.066 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr10_+_20148457 0.059 ENSMUST00000020173.8
Map7
microtubule-associated protein 7
chr5_+_31054766 0.057 ENSMUST00000013773.5
ENSMUST00000114646.1
Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chrX_+_157818435 0.057 ENSMUST00000087157.4
Klhl34
kelch-like 34
chr19_-_4201591 0.051 ENSMUST00000025740.6
Rad9a
RAD9 homolog A
chr11_-_103954015 0.049 ENSMUST00000103075.4
Nsf
N-ethylmaleimide sensitive fusion protein
chr18_+_53176345 0.049 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr14_+_26638074 0.047 ENSMUST00000022429.2
Arf4
ADP-ribosylation factor 4
chr4_-_155653184 0.046 ENSMUST00000030937.1
Mmp23
matrix metallopeptidase 23
chr2_+_164833841 0.046 ENSMUST00000152721.1
Ctsa
cathepsin A
chr7_+_105640522 0.044 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
Timm10b



translocase of inner mitochondrial membrane 10B



chr14_-_55643800 0.038 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr7_+_105640448 0.037 ENSMUST00000058333.3
Timm10b
translocase of inner mitochondrial membrane 10B
chr2_+_130274437 0.037 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chr10_+_20148920 0.025 ENSMUST00000116259.3
Map7
microtubule-associated protein 7
chr17_+_35424870 0.022 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr14_-_55643523 0.018 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr5_+_31054821 0.018 ENSMUST00000174367.1
ENSMUST00000170329.1
ENSMUST00000031049.6
Cad


carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase


chr3_-_88177671 0.016 ENSMUST00000181837.1
1700113A16Rik
RIKEN cDNA 1700113A16 gene
chr1_+_87327044 0.015 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chrX_-_8145679 0.009 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr5_-_100416115 0.007 ENSMUST00000182886.1
ENSMUST00000094578.4
Sec31a

Sec31 homolog A (S. cerevisiae)

chr5_+_143403819 0.005 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chrX_-_136741155 0.002 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr14_+_26638237 0.002 ENSMUST00000112318.3
Arf4
ADP-ribosylation factor 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.5 1.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 0.5 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 0.5 GO:1990523 bone regeneration(GO:1990523)
0.2 0.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 1.9 GO:0015816 glycine transport(GO:0015816)
0.1 0.5 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.5 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.5 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 0.4 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.1 1.4 GO:0007141 male meiosis I(GO:0007141)
0.1 3.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 2.8 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 1.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.9 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 1.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.3 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.6 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.2 0.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 1.0 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 2.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 2.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 3.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 2.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) activin binding(GO:0048185)
0.0 2.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.5 GO:0016790 thiolester hydrolase activity(GO:0016790)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.2 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.6 PID_IL4_2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.4 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.8 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 1.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import