Motif ID: Cux1

Z-value: 0.987


Transcription factors associated with Cux1:

Gene SymbolEntrez IDGene Name
Cux1 ENSMUSG00000029705.11 Cux1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cux1mm10_v2_chr5_-_136567242_1365672870.802.0e-09Click!


Activity profile for motif Cux1.

activity profile for motif Cux1


Sorted Z-values histogram for motif Cux1

Sorted Z-values for motif Cux1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cux1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_78499087 8.883 ENSMUST00000017488.4
Vtn
vitronectin
chr7_-_103827922 5.357 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr11_-_42182924 5.255 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr2_+_71528657 5.032 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr2_+_71529085 4.679 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr10_-_117282262 4.631 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr9_-_112232449 3.753 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr11_+_32286946 3.572 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr5_+_66968559 3.462 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr9_-_77347816 3.270 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr3_-_53657339 3.257 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr7_-_140154712 3.145 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr2_-_164171113 3.074 ENSMUST00000045196.3
Kcns1
K+ voltage-gated channel, subfamily S, 1
chr2_-_25224653 3.056 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr4_+_119814495 3.016 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr7_-_19166119 3.011 ENSMUST00000094790.3
Gipr
gastric inhibitory polypeptide receptor
chr9_-_112185726 2.953 ENSMUST00000160240.1
ENSMUST00000162065.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr9_-_112185939 2.896 ENSMUST00000070218.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr15_+_21111452 2.882 ENSMUST00000075132.6
Cdh12
cadherin 12
chr17_-_68004075 2.836 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr5_+_117841839 2.777 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr7_-_19698383 2.642 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr5_+_66968961 2.619 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr13_-_92030897 2.483 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr8_+_68880491 2.476 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr14_+_68083853 2.456 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr12_+_108334341 2.449 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr9_-_120068263 2.427 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr7_-_19698206 2.369 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr3_+_68572245 2.277 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr15_-_37791993 2.245 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr5_-_122050102 2.237 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr7_-_99695809 2.226 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr5_+_110544326 2.199 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr18_+_37447641 2.178 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr17_-_33760306 2.133 ENSMUST00000173860.1
Rab11b
RAB11B, member RAS oncogene family
chr19_-_57360668 2.072 ENSMUST00000181921.1
B230217O12Rik
RIKEN cDNA B230217O12 gene
chr1_+_171840607 2.045 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr1_+_91053422 2.009 ENSMUST00000097650.3
ENSMUST00000068167.6
ENSMUST00000097649.3
Lrrfip1


leucine rich repeat (in FLII) interacting protein 1


chr15_-_78120011 1.915 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr4_-_42034726 1.903 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr3_-_89101907 1.870 ENSMUST00000081848.8
Fdps
farnesyl diphosphate synthetase
chr5_-_43981757 1.843 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr13_-_34130345 1.735 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr2_+_178414512 1.705 ENSMUST00000094251.4
Fam217b
family with sequence similarity 217, member B
chr12_-_84698769 1.686 ENSMUST00000095550.2
Syndig1l
synapse differentiation inducing 1 like
chr10_+_81628570 1.677 ENSMUST00000153573.1
ENSMUST00000119336.1
Ankrd24

ankyrin repeat domain 24

chr9_+_111271832 1.668 ENSMUST00000060711.5
Epm2aip1
EPM2A (laforin) interacting protein 1
chr5_-_70842617 1.663 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr5_+_63649335 1.639 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr2_+_158610731 1.618 ENSMUST00000045738.4
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr18_-_38211957 1.576 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr4_+_120854786 1.561 ENSMUST00000071093.2
Rims3
regulating synaptic membrane exocytosis 3
chr11_+_62551167 1.555 ENSMUST00000019649.3
Ubb
ubiquitin B
chr19_+_34217588 1.536 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chr9_+_15239045 1.493 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr7_-_74013676 1.483 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr2_-_24049389 1.480 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chr7_+_141461728 1.445 ENSMUST00000167491.1
ENSMUST00000165194.1
Efcab4a

EF-hand calcium binding domain 4A

chr15_+_74516196 1.442 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr13_+_43615710 1.424 ENSMUST00000059986.2
Rnf182
ring finger protein 182
chr9_-_40346290 1.417 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr2_+_57238297 1.416 ENSMUST00000112618.2
ENSMUST00000028167.2
Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr11_+_32300069 1.414 ENSMUST00000020535.1
Hbq1a
hemoglobin, theta 1A
chr18_+_37484955 1.406 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr2_-_5063996 1.379 ENSMUST00000114996.1
Optn
optineurin
chr10_+_14523062 1.372 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr15_-_67113909 1.334 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chrX_+_114474312 1.331 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr7_-_137410717 1.326 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr16_+_35022394 1.321 ENSMUST00000061156.8
Ptplb
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr7_+_29309429 1.316 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr13_-_45964964 1.290 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1


chr17_-_27728889 1.290 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr11_+_69088490 1.281 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr2_+_32570858 1.258 ENSMUST00000140592.1
ENSMUST00000028151.6
Dpm2

dolichol-phosphate (beta-D) mannosyltransferase 2

chr3_+_98013503 1.236 ENSMUST00000079812.6
Notch2
notch 2
chr3_+_89715016 1.220 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr4_+_41465134 1.218 ENSMUST00000030154.6
Nudt2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr16_+_3908801 1.207 ENSMUST00000145150.2
ENSMUST00000040881.7
Cluap1

clusterin associated protein 1

chr4_+_123183456 1.198 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr3_+_65109343 1.196 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr6_-_113501818 1.187 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr6_-_124741374 1.180 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr11_+_87760533 1.170 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr1_+_34801704 1.169 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr7_+_44384098 1.163 ENSMUST00000118962.1
ENSMUST00000118831.1
Syt3

synaptotagmin III

chr8_+_12385769 1.159 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr1_-_83408190 1.154 ENSMUST00000160953.1
Sphkap
SPHK1 interactor, AKAP domain containing
chr2_-_32694120 1.151 ENSMUST00000028148.4
Fpgs
folylpolyglutamyl synthetase
chr10_-_89732253 1.148 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr9_+_56418624 1.141 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr7_-_13054665 1.140 ENSMUST00000182515.1
ENSMUST00000069289.8
Mzf1

myeloid zinc finger 1

chr9_+_26999668 1.139 ENSMUST00000039161.8
Thyn1
thymocyte nuclear protein 1
chr10_+_103367748 1.136 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr11_-_120713725 1.133 ENSMUST00000106154.1
ENSMUST00000106155.3
ENSMUST00000055424.6
ENSMUST00000026137.7
Stra13



stimulated by retinoic acid 13



chr15_-_79505241 1.132 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr3_+_89215170 1.127 ENSMUST00000029682.4
Thbs3
thrombospondin 3
chr7_+_44384803 1.127 ENSMUST00000120262.1
Syt3
synaptotagmin III
chr15_+_76660564 1.126 ENSMUST00000004294.10
Kifc2
kinesin family member C2
chr3_+_89215192 1.114 ENSMUST00000142051.1
ENSMUST00000119084.1
Thbs3

thrombospondin 3

chr7_-_27178835 1.083 ENSMUST00000093040.6
Rab4b
RAB4B, member RAS oncogene family
chrY_+_90755657 1.083 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr8_-_54724474 1.075 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr10_+_62071014 1.070 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr5_-_3596071 1.054 ENSMUST00000121877.1
Rbm48
RNA binding motif protein 48
chr10_-_25200110 1.045 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chrX_+_7722214 1.004 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr11_-_96075581 0.991 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr12_+_64917901 0.980 ENSMUST00000058135.4
Gm527
predicted gene 527
chr2_+_152427639 0.978 ENSMUST00000128737.1
6820408C15Rik
RIKEN cDNA 6820408C15 gene
chr11_-_96075655 0.972 ENSMUST00000090541.5
Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr5_+_3596066 0.967 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr19_+_8819401 0.966 ENSMUST00000096753.3
Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr16_-_90934802 0.966 ENSMUST00000023694.3
1110004E09Rik
RIKEN cDNA 1110004E09 gene
chr7_+_113207465 0.955 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr16_-_33967032 0.954 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr18_+_37442517 0.950 ENSMUST00000056915.1
Pcdhb13
protocadherin beta 13
chr10_+_81628702 0.944 ENSMUST00000129622.1
Ankrd24
ankyrin repeat domain 24
chr4_+_136310991 0.925 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr3_+_95624971 0.920 ENSMUST00000058230.6
ENSMUST00000037983.4
Ensa

endosulfine alpha

chr16_-_90934723 0.915 ENSMUST00000149833.1
1110004E09Rik
RIKEN cDNA 1110004E09 gene
chr5_+_66676098 0.904 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr8_-_73353477 0.899 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr11_-_50931612 0.892 ENSMUST00000109124.3
Zfp354b
zinc finger protein 354B
chr6_+_49367739 0.882 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
Fam221a


family with sequence similarity 221, member A


chr4_+_155831272 0.872 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr10_+_60346851 0.870 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
4632428N05Rik


RIKEN cDNA 4632428N05 gene


chr15_+_5185700 0.867 ENSMUST00000081640.5
Ttc33
tetratricopeptide repeat domain 33
chr3_+_19957037 0.859 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr2_-_178414460 0.859 ENSMUST00000058678.4
Ppp1r3d
protein phosphatase 1, regulatory subunit 3D
chr12_+_4769278 0.855 ENSMUST00000020967.4
Pfn4
profilin family, member 4
chr4_+_136310936 0.854 ENSMUST00000131671.1
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr14_+_121035194 0.851 ENSMUST00000135010.1
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr9_+_107554633 0.834 ENSMUST00000010211.4
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
chr4_-_116144609 0.833 ENSMUST00000030469.4
Lurap1
leucine rich adaptor protein 1
chr4_+_118620799 0.826 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chr13_-_30974023 0.819 ENSMUST00000021785.6
Exoc2
exocyst complex component 2
chr10_+_79960145 0.817 ENSMUST00000045247.7
Wdr18
WD repeat domain 18
chr14_+_70077375 0.815 ENSMUST00000035908.1
Egr3
early growth response 3
chr8_+_85037151 0.814 ENSMUST00000166592.1
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr14_+_118137101 0.802 ENSMUST00000022728.2
Gpr180
G protein-coupled receptor 180
chr18_+_14424821 0.800 ENSMUST00000069552.5
Gm5160
predicted gene 5160
chr1_+_16688405 0.800 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr11_-_97744659 0.785 ENSMUST00000018691.8
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr10_+_79669410 0.784 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr11_+_70540260 0.781 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
Pld2


phospholipase D2


chr10_-_32890462 0.781 ENSMUST00000092602.1
Nkain2
Na+/K+ transporting ATPase interacting 2
chr1_-_179546261 0.780 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr9_-_119157055 0.776 ENSMUST00000010795.4
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
chr7_+_81523555 0.775 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr7_+_24587543 0.775 ENSMUST00000077191.6
Ethe1
ethylmalonic encephalopathy 1
chr17_-_87797994 0.773 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr11_+_120713919 0.772 ENSMUST00000026139.7
ENSMUST00000151852.1
Lrrc45

leucine rich repeat containing 45

chrX_+_7722267 0.768 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr9_+_58253164 0.763 ENSMUST00000034883.5
Stoml1
stomatin-like 1
chr4_+_99929414 0.759 ENSMUST00000058351.9
Pgm2
phosphoglucomutase 2
chr4_-_149126688 0.753 ENSMUST00000030815.2
Cort
cortistatin
chr9_+_54980880 0.750 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_+_55768184 0.746 ENSMUST00000121492.1
ENSMUST00000171077.1
ENSMUST00000060416.8
ENSMUST00000094360.6
ENSMUST00000165045.2
ENSMUST00000173835.1
Siglech





sialic acid binding Ig-like lectin H





chr4_+_136310952 0.738 ENSMUST00000105850.1
ENSMUST00000148843.3
Hnrnpr

heterogeneous nuclear ribonucleoprotein R

chr6_-_24527546 0.738 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr3_-_88296838 0.738 ENSMUST00000010682.3
Tsacc
TSSK6 activating co-chaperone
chr1_+_75436002 0.734 ENSMUST00000131545.1
ENSMUST00000141124.1
Gmppa

GDP-mannose pyrophosphorylase A

chr10_+_20952547 0.734 ENSMUST00000105525.4
Ahi1
Abelson helper integration site 1
chr11_-_59839745 0.733 ENSMUST00000141415.1
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr8_-_54724317 0.726 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr19_-_46395722 0.725 ENSMUST00000040270.4
Actr1a
ARP1 actin-related protein 1A, centractin alpha
chr8_-_13677575 0.721 ENSMUST00000117551.2
Rasa3
RAS p21 protein activator 3
chr5_+_135009152 0.716 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr17_-_85090204 0.713 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr11_+_69095217 0.710 ENSMUST00000101004.2
Per1
period circadian clock 1
chr4_+_46489248 0.710 ENSMUST00000030018.4
Nans
N-acetylneuraminic acid synthase (sialic acid synthase)
chr4_+_42035113 0.710 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr3_-_88296979 0.707 ENSMUST00000107556.3
Tsacc
TSSK6 activating co-chaperone
chr15_+_89499598 0.699 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr8_+_83608175 0.699 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr5_-_34288318 0.695 ENSMUST00000094868.3
Zfyve28
zinc finger, FYVE domain containing 28
chr1_+_55088132 0.692 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chrX_+_169685191 0.681 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr4_-_62360436 0.681 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr5_-_145201829 0.676 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr7_-_89941084 0.675 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr15_+_84192223 0.674 ENSMUST00000023071.6
Samm50
sorting and assembly machinery component 50 homolog (S. cerevisiae)
chr1_+_64690443 0.673 ENSMUST00000114077.1
Ccnyl1
cyclin Y-like 1
chr3_+_88297147 0.662 ENSMUST00000164166.1
ENSMUST00000168062.1
Cct3

chaperonin containing Tcp1, subunit 3 (gamma)

chr7_-_27674516 0.661 ENSMUST00000036453.7
ENSMUST00000108341.1
Map3k10

mitogen-activated protein kinase kinase kinase 10

chr7_-_28962223 0.660 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr11_-_50325599 0.657 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr10_-_127121125 0.653 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr11_+_86683985 0.651 ENSMUST00000108022.1
ENSMUST00000108021.1
Ptrh2

peptidyl-tRNA hydrolase 2

chr7_+_81523531 0.649 ENSMUST00000181903.1
2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr6_+_124931378 0.648 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr7_-_24587612 0.648 ENSMUST00000094705.2
Zfp575
zinc finger protein 575
chr8_+_84689308 0.641 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chr19_-_10869757 0.639 ENSMUST00000120524.1
ENSMUST00000025645.7
Tmem132a

transmembrane protein 132A

chr15_+_80287234 0.639 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr18_+_24470844 0.637 ENSMUST00000097646.3
2700062C07Rik
RIKEN cDNA 2700062C07 gene
chr19_-_8819278 0.633 ENSMUST00000088092.5
Ttc9c
tetratricopeptide repeat domain 9C
chr15_+_59315088 0.627 ENSMUST00000100640.4
Sqle
squalene epoxidase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
1.7 5.0 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
1.5 4.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.2 2.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.9 2.8 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.8 9.0 GO:0097421 liver regeneration(GO:0097421)
0.8 2.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.7 2.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 2.0 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.6 5.3 GO:0071420 cellular response to histamine(GO:0071420)
0.5 2.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.5 2.4 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.5 1.4 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.4 1.3 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.4 1.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.4 1.2 GO:0061744 motor behavior(GO:0061744)
0.4 1.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 1.5 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.3 2.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 1.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.4 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.3 0.3 GO:0050955 thermoception(GO:0050955)
0.3 1.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.3 1.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 0.6 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3 0.8 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.6 GO:0007144 female meiosis I(GO:0007144)
0.2 1.7 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.2 0.7 GO:0035844 positive regulation of polarized epithelial cell differentiation(GO:0030862) cloaca development(GO:0035844)
0.2 1.2 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.2 1.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 1.9 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.2 5.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.2 1.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 1.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.9 GO:0007412 axon target recognition(GO:0007412)
0.2 2.2 GO:0060346 bone trabecula formation(GO:0060346)
0.2 10.4 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 0.6 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 1.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.6 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 1.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 1.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021) modification of dendritic spine(GO:0098886)
0.2 2.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.0 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 0.6 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 1.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 1.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 0.5 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.2 1.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 1.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.5 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.2 0.5 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 1.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.5 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 0.8 GO:0019236 response to pheromone(GO:0019236)
0.2 0.5 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.2 1.4 GO:0071569 protein ufmylation(GO:0071569)
0.2 0.5 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.2 0.6 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 3.8 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1 0.7 GO:1904717 positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.1 0.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 2.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.8 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.6 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.2 GO:0007614 short-term memory(GO:0007614)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 1.7 GO:0042407 cristae formation(GO:0042407)
0.1 0.5 GO:0034214 protein hexamerization(GO:0034214)
0.1 2.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.3 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.8 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 0.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.8 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 0.9 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 2.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 0.9 GO:0046688 response to copper ion(GO:0046688)
0.1 0.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.8 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.4 GO:0022900 electron transport chain(GO:0022900)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.8 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 5.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.2 GO:0015744 succinate transport(GO:0015744)
0.1 0.1 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of developmental pigmentation(GO:0048087) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0030431 sleep(GO:0030431)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 1.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 7.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0014002 astrocyte development(GO:0014002)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 2.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.6 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0003097 renal water transport(GO:0003097) renal water absorption(GO:0070295)
0.0 0.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 3.2 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438) anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.7 5.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.3 5.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.8 2.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.6 2.5 GO:0042627 chylomicron(GO:0042627)
0.5 1.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 1.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.4 5.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 1.6 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 3.1 GO:0045298 tubulin complex(GO:0045298)
0.3 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 3.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.2 GO:1990393 3M complex(GO:1990393)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.2 1.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 2.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 2.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.7 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587)
0.1 1.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.7 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 3.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.9 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.5 GO:0001741 XY body(GO:0001741)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.1 0.7 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.5 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 4.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 4.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.2 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.5 4.6 GO:0003796 lysozyme activity(GO:0003796)
1.3 5.4 GO:0031720 haptoglobin binding(GO:0031720)
0.9 2.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.9 5.3 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 1.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.5 8.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5 2.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.5 1.4 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.5 1.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 1.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.2 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.3 0.3 GO:0051379 epinephrine binding(GO:0051379)
0.3 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 1.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 0.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 0.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 1.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 2.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.5 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.2 0.5 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.5 GO:0009881 photoreceptor activity(GO:0009881)
0.2 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.2 3.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 3.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 1.4 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.5 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.2 0.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 3.1 GO:0031489 myosin V binding(GO:0031489)
0.1 1.0 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 1.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.5 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.4 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.3 GO:0004568 chitinase activity(GO:0004568)
0.1 0.7 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 2.5 GO:0043274 phospholipase binding(GO:0043274)
0.1 3.1 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 3.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 1.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.7 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 3.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 5.9 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 1.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 5.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.8 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 2.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.0 GO:0016208 AMP binding(GO:0016208)
0.0 1.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.8 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 7.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 2.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0005504 fatty acid binding(GO:0005504)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 2.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 7.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.8 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.8 PID_INSULIN_PATHWAY Insulin Pathway
0.0 3.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.1 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.7 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.1 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 2.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.3 5.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 5.3 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.3 2.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 4.9 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 1.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.4 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.8 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.1 1.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 4.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.7 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.5 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 8.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.2 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.8 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.3 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 2.4 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 0.7 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.1 0.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 2.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.5 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis