Motif ID: Dbp

Z-value: 0.955


Transcription factors associated with Dbp:

Gene SymbolEntrez IDGene Name
Dbp ENSMUSG00000059824.4 Dbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbpmm10_v2_chr7_+_45705088_45705292-0.501.5e-03Click!


Activity profile for motif Dbp.

activity profile for motif Dbp


Sorted Z-values histogram for motif Dbp

Sorted Z-values for motif Dbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Dbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_123264076 7.448 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr10_+_85386813 5.425 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr12_+_61523889 4.578 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr5_-_44799643 3.973 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr10_-_64090265 3.725 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chrX_-_72656135 3.601 ENSMUST00000055966.6
 Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr6_-_91807424 3.556 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chrX_-_165327376 3.524 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr8_+_68880491 3.488 ENSMUST00000015712.8
 Lpl
lipoprotein lipase
chr5_+_150259922 3.445 ENSMUST00000087204.5
 Fry
furry homolog (Drosophila)
chr10_-_64090241 3.354 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr1_+_66386968 3.222 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr6_-_91807318 3.190 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr3_-_26133734 3.141 ENSMUST00000108308.3
ENSMUST00000075054.4
 Nlgn1

neuroligin 1

chrX_-_43167817 3.086 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr5_-_92042630 3.026 ENSMUST00000113140.1
ENSMUST00000113143.1
 Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr14_-_93888732 2.879 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chr2_+_65845833 2.852 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_+_99263224 2.820 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr7_-_119184374 2.811 ENSMUST00000084650.4
 Gpr139
G protein-coupled receptor 139

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 131 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 10.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.6 9.8 GO:1902993 positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 7.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 7.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.7 6.7 GO:0014824 artery smooth muscle contraction(GO:0014824)
2.0 5.9 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
1.5 4.4 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 4.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 4.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 3.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 3.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.9 3.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 3.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.6 3.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.4 3.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.4 3.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 3.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.3 3.1 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 3.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 3.0 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 28.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 12.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 8.0 GO:0044295 axonal growth cone(GO:0044295)
0.5 6.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 5.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 5.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 4.4 GO:0032433 filopodium tip(GO:0032433)
0.5 3.5 GO:0042627 chylomicron(GO:0042627)
0.1 3.5 GO:0034707 chloride channel complex(GO:0034707)
0.4 3.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.7 GO:0071565 nBAF complex(GO:0071565)
0.1 2.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.9 GO:0043195 terminal bouton(GO:0043195)
0.2 1.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.8 GO:0035371 microtubule plus-end(GO:0035371)
0.4 1.7 GO:0031673 H zone(GO:0031673)
0.2 1.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.5 GO:0097440 apical dendrite(GO:0097440)
0.3 1.4 GO:0032437 cuticular plate(GO:0032437)
0.1 1.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 12.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 8.6 GO:0045499 chemorepellent activity(GO:0045499)
0.4 6.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 6.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 6.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 5.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 4.4 GO:0030275 LRR domain binding(GO:0030275)
0.4 4.0 GO:0030274 LIM domain binding(GO:0030274)
1.2 3.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 3.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 3.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 3.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.8 GO:0005516 calmodulin binding(GO:0005516)
0.6 2.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 2.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 2.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.5 2.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 4.4 PID_FGF_PATHWAY FGF signaling pathway
0.0 3.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 3.3 PID_LKB1_PATHWAY LKB1 signaling events
0.1 2.9 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 2.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.1 1.9 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.9 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.4 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 1.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 10.4 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 6.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.4 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 3.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 3.5 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 3.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 2.8 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 2.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.6 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.3 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors