Motif ID: E2f4

Z-value: 2.212


Transcription factors associated with E2f4:

Gene SymbolEntrez IDGene Name
E2f4 ENSMUSG00000014859.8 E2f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f4mm10_v2_chr8_+_105297663_1052977420.764.8e-08Click!


Activity profile for motif E2f4.

activity profile for motif E2f4


Sorted Z-values histogram for motif E2f4

Sorted Z-values for motif E2f4



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_34751502 19.794 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr8_-_53638945 19.337 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr19_+_6084983 18.547 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr11_-_101551837 18.183 ENSMUST00000017290.4
Brca1
breast cancer 1
chr14_-_47418407 16.270 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr1_-_169531343 15.276 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr6_+_124830217 15.227 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr1_-_189688074 14.603 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr9_+_72438534 13.368 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr4_+_134510999 13.124 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr9_+_72438519 13.078 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr1_-_169531447 13.035 ENSMUST00000111368.1
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr2_+_163054682 10.668 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr2_-_26503814 10.127 ENSMUST00000028288.4
Notch1
notch 1
chr4_-_133967296 10.077 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr18_+_34751803 10.024 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr4_-_133967235 9.719 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr10_+_79997463 9.687 ENSMUST00000171637.1
ENSMUST00000043866.7
Abca7

ATP-binding cassette, sub-family A (ABC1), member 7

chr15_+_57912199 9.579 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chr4_-_116123618 9.363 ENSMUST00000102704.3
ENSMUST00000102705.3
Rad54l

RAD54 like (S. cerevisiae)

chr4_+_11558914 9.150 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr10_-_88146867 8.755 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr17_+_50698525 7.584 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr17_-_28350747 7.500 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr9_-_82975475 7.417 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr9_-_32344237 7.276 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr5_-_112228934 7.233 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr17_-_25727364 7.128 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr13_-_23745511 7.128 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr4_-_133967893 6.994 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr17_-_24251382 6.870 ENSMUST00000115390.3
Ccnf
cyclin F
chr1_+_157412352 6.758 ENSMUST00000061537.5
2810025M15Rik
RIKEN cDNA 2810025M15 gene
chr17_-_28350600 6.644 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr6_+_113531675 6.354 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr5_-_112228900 5.818 ENSMUST00000182509.1
Miat
myocardial infarction associated transcript (non-protein coding)
chr4_-_132345686 5.763 ENSMUST00000030726.6
Rcc1
regulator of chromosome condensation 1
chr13_+_23535411 5.639 ENSMUST00000080859.5
Hist1h3g
histone cluster 1, H3g
chr4_-_133967953 5.603 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_98907801 5.525 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr2_-_172940299 5.435 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr4_-_132345715 5.231 ENSMUST00000084250.4
Rcc1
regulator of chromosome condensation 1
chr7_-_38107490 5.064 ENSMUST00000108023.3
Ccne1
cyclin E1
chr15_+_55307743 4.925 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr9_+_92250039 4.837 ENSMUST00000093801.3
Plscr1
phospholipid scramblase 1
chr10_+_17723220 4.575 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_+_74601548 4.223 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr19_+_5366764 4.092 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr1_-_77515048 4.053 ENSMUST00000027451.6
Epha4
Eph receptor A4
chrY_-_90754821 4.047 ENSMUST00000177893.1
Gm21860
predicted gene, 21860
chr1_+_74601441 4.046 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chr4_-_58553553 4.023 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chrX_-_164980310 3.918 ENSMUST00000004715.1
ENSMUST00000112248.2
Mospd2

motile sperm domain containing 2

chr7_-_109865586 3.915 ENSMUST00000007423.5
ENSMUST00000106728.2
ENSMUST00000106729.1
Scube2


signal peptide, CUB domain, EGF-like 2


chr12_-_4233958 3.747 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr2_+_101678403 3.736 ENSMUST00000004949.7
Traf6
TNF receptor-associated factor 6
chr7_+_126781483 3.688 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr17_+_88440711 3.515 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chr4_-_58553311 3.468 ENSMUST00000107571.1
ENSMUST00000055018.4
Lpar1

lysophosphatidic acid receptor 1

chrX_-_164980279 3.409 ENSMUST00000112247.2
Mospd2
motile sperm domain containing 2
chr5_-_25705791 3.396 ENSMUST00000030773.7
Xrcc2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr2_-_63184253 3.224 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr5_+_9100681 3.202 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr1_-_57377476 3.092 ENSMUST00000181949.1
4930558J18Rik
RIKEN cDNA 4930558J18 gene
chr7_-_92874196 2.969 ENSMUST00000032877.9
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr5_+_33721724 2.932 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
Fgfr3



fibroblast growth factor receptor 3



chr3_-_142881942 2.917 ENSMUST00000043812.8
Pkn2
protein kinase N2
chr4_+_43058939 2.893 ENSMUST00000079978.6
Unc13b
unc-13 homolog B (C. elegans)
chr15_-_98831498 2.883 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr18_-_39490649 2.864 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr11_-_106999369 2.860 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr1_+_52630692 2.799 ENSMUST00000165859.1
Tmem194b
transmembrane protein 194B
chr12_+_9029982 2.756 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr11_-_106999482 2.746 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr7_+_97579868 2.737 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr14_+_31019125 2.692 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chrX_+_105079761 2.661 ENSMUST00000119477.1
Pbdc1
polysaccharide biosynthesis domain containing 1
chr13_-_73937761 2.571 ENSMUST00000022053.8
Trip13
thyroid hormone receptor interactor 13
chr5_+_88764983 2.558 ENSMUST00000031311.9
Dck
deoxycytidine kinase
chr17_-_35046726 2.459 ENSMUST00000097338.4
Msh5
mutS homolog 5 (E. coli)
chr11_+_16951371 2.329 ENSMUST00000109635.1
ENSMUST00000061327.1
Fbxo48

F-box protein 48

chr16_-_90727329 2.320 ENSMUST00000099554.4
Mis18a
MIS18 kinetochore protein homolog A (S. pombe)
chrX_+_105079735 2.275 ENSMUST00000033577.4
Pbdc1
polysaccharide biosynthesis domain containing 1
chr4_+_43059028 2.274 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr9_-_65580040 2.033 ENSMUST00000068944.7
Plekho2
pleckstrin homology domain containing, family O member 2
chr9_+_119937606 2.016 ENSMUST00000035100.5
Ttc21a
tetratricopeptide repeat domain 21A
chr14_+_31019159 2.012 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr2_-_63184170 1.920 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr12_+_106010263 1.889 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
Vrk1


vaccinia related kinase 1


chr11_+_101552188 1.885 ENSMUST00000147239.1
Nbr1
neighbor of Brca1 gene 1
chr2_-_145935014 1.871 ENSMUST00000001818.4
Crnkl1
Crn, crooked neck-like 1 (Drosophila)
chr10_+_88147061 1.821 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr4_+_84884276 1.816 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr4_-_43562397 1.766 ENSMUST00000030187.7
Tln1
talin 1
chr17_-_84187939 1.740 ENSMUST00000060366.6
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr9_-_44134481 1.735 ENSMUST00000180670.1
Gm10687
predicted gene 10687
chr11_+_101552135 1.641 ENSMUST00000103099.1
Nbr1
neighbor of Brca1 gene 1
chr8_-_64205970 1.606 ENSMUST00000066166.4
Tll1
tolloid-like
chr17_-_17624458 1.585 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr5_-_33652296 1.583 ENSMUST00000151081.1
ENSMUST00000101354.3
Slbp

stem-loop binding protein

chr10_-_19907645 1.517 ENSMUST00000166511.1
ENSMUST00000020182.8
Pex7

peroxisomal biogenesis factor 7

chr15_-_76639840 1.515 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr12_+_4234023 1.508 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr4_+_84884418 1.484 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr2_-_166713758 1.451 ENSMUST00000036719.5
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr14_-_33978751 1.378 ENSMUST00000166737.1
Zfp488
zinc finger protein 488
chr2_+_181319714 1.370 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr1_-_157412576 1.330 ENSMUST00000078308.6
ENSMUST00000139470.1
Rasal2

RAS protein activator like 2

chr10_-_81427114 1.282 ENSMUST00000078185.7
ENSMUST00000020461.8
ENSMUST00000105321.3
Nfic


nuclear factor I/C


chr17_+_29490812 1.277 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr10_+_88146992 1.251 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr2_+_181319806 1.208 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr4_-_58553184 1.205 ENSMUST00000145361.1
Lpar1
lysophosphatidic acid receptor 1
chr2_+_106695594 1.194 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chr2_-_62646146 1.168 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr9_-_83441065 1.168 ENSMUST00000034791.8
ENSMUST00000034793.8
Lca5

Leber congenital amaurosis 5 (human)

chr2_+_153649617 1.134 ENSMUST00000109771.1
Dnmt3b
DNA methyltransferase 3B
chr17_-_12507704 1.127 ENSMUST00000024595.2
Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr14_-_87141114 1.117 ENSMUST00000168889.1
Diap3
diaphanous homolog 3 (Drosophila)
chr10_-_91123955 1.101 ENSMUST00000164505.1
ENSMUST00000170810.1
ENSMUST00000076694.6
Slc25a3


solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3


chr6_-_56704673 1.084 ENSMUST00000170382.2
Lsm5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_-_37110257 1.060 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr2_+_103970221 1.045 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr12_+_117843873 1.025 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr19_-_4397052 0.997 ENSMUST00000075856.4
Kdm2a
lysine (K)-specific demethylase 2A
chr7_+_97371604 0.961 ENSMUST00000098300.4
Alg8
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr1_-_179803625 0.948 ENSMUST00000027768.7
Ahctf1
AT hook containing transcription factor 1
chrX_-_78583782 0.944 ENSMUST00000177904.1
Prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr16_-_59632520 0.942 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr15_-_39943963 0.934 ENSMUST00000110305.2
Lrp12
low density lipoprotein-related protein 12
chr15_+_102406143 0.920 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr8_-_69974367 0.884 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr15_-_38078842 0.841 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr1_+_134415414 0.833 ENSMUST00000112237.1
Adipor1
adiponectin receptor 1
chrX_+_162901567 0.765 ENSMUST00000112303.1
ENSMUST00000033727.7
Ctps2

cytidine 5'-triphosphate synthase 2

chrX_-_78583882 0.756 ENSMUST00000114025.1
ENSMUST00000134602.1
ENSMUST00000114024.2
Prrg1


proline rich Gla (G-carboxyglutamic acid) 1


chr10_+_58255465 0.752 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
Gcc2


GRIP and coiled-coil domain containing 2


chr17_+_34982154 0.733 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_+_57708534 0.730 ENSMUST00000043990.7
ENSMUST00000142807.1
Edc3

enhancer of mRNA decapping 3 homolog (S. cerevisiae)

chr17_-_87025353 0.714 ENSMUST00000024957.6
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
chr2_+_71786923 0.676 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chrX_+_164980592 0.661 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fancb


Fanconi anemia, complementation group B


chr17_+_34982099 0.637 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_132463873 0.623 ENSMUST00000102567.3
Med18
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr4_-_59783800 0.588 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr13_+_73937799 0.568 ENSMUST00000099384.2
Brd9
bromodomain containing 9
chr9_-_60688118 0.530 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr2_+_174076296 0.517 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
Stx16


syntaxin 16


chr11_+_108425192 0.469 ENSMUST00000150863.2
ENSMUST00000061287.5
ENSMUST00000149683.2
Cep112


centrosomal protein 112


chr17_+_34981847 0.422 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_+_162901226 0.417 ENSMUST00000101095.2
Ctps2
cytidine 5'-triphosphate synthase 2
chrX_+_162901762 0.414 ENSMUST00000112302.1
ENSMUST00000112301.1
Ctps2

cytidine 5'-triphosphate synthase 2

chr5_-_33652339 0.411 ENSMUST00000075670.6
Slbp
stem-loop binding protein
chr7_-_127208423 0.376 ENSMUST00000120705.1
Tbc1d10b
TBC1 domain family, member 10b
chr12_+_99884498 0.353 ENSMUST00000153627.1
Tdp1
tyrosyl-DNA phosphodiesterase 1
chr6_+_70726430 0.325 ENSMUST00000103410.1
Igkc
immunoglobulin kappa constant
chr6_+_37870786 0.315 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr10_+_127677064 0.282 ENSMUST00000118612.1
ENSMUST00000048099.4
Tmem194

transmembrane protein 194

chr1_+_57377593 0.258 ENSMUST00000042734.2
1700066M21Rik
RIKEN cDNA 1700066M21 gene
chrX_-_12762069 0.221 ENSMUST00000096495.4
ENSMUST00000076016.5
Med14

mediator complex subunit 14

chr5_+_113772748 0.193 ENSMUST00000026937.5
ENSMUST00000112311.1
ENSMUST00000112312.1
Iscu


IscU iron-sulfur cluster scaffold homolog (E. coli)


chr11_-_6606053 0.180 ENSMUST00000045713.3
Nacad
NAC alpha domain containing
chr1_-_9748376 0.172 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr7_-_127422002 0.125 ENSMUST00000106300.1
Zfp688
zinc finger protein 688
chr2_+_132686931 0.117 ENSMUST00000061891.4
1110034G24Rik
RIKEN cDNA 1110034G24 gene
chr1_-_151500794 0.086 ENSMUST00000076110.4
Rnf2
ring finger protein 2
chr12_+_76533540 0.077 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrY_+_90784738 0.048 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr1_+_179803376 0.022 ENSMUST00000097454.2
Gm10518
predicted gene 10518

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 18.5 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
6.1 18.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
3.4 10.1 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
2.8 8.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
2.2 31.0 GO:0070986 left/right axis specification(GO:0070986)
2.2 8.7 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.9 9.7 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
1.8 5.4 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.6 4.8 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.6 14.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
1.6 4.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.5 7.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.4 4.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.3 32.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
1.3 5.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
1.2 3.7 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
1.0 13.1 GO:0035881 amacrine cell differentiation(GO:0035881)
1.0 6.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.0 2.9 GO:0061144 alveolar secondary septum development(GO:0061144)
0.9 6.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.8 3.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.8 7.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.8 3.9 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.8 28.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.7 7.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.7 19.8 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.6 2.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.6 2.6 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.6 9.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.6 16.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.6 2.9 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.5 3.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.5 2.5 GO:0051026 chiasma assembly(GO:0051026)
0.5 1.9 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.5 5.5 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.4 19.3 GO:0006284 base-excision repair(GO:0006284)
0.4 2.6 GO:0007144 female meiosis I(GO:0007144)
0.4 1.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.4 2.7 GO:0016584 nucleosome positioning(GO:0016584)
0.4 2.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 14.6 GO:0051310 metaphase plate congression(GO:0051310)
0.4 1.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.3 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 1.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.3 16.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.3 1.7 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 0.8 GO:1905077 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) negative regulation of interleukin-17 secretion(GO:1905077)
0.3 5.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 10.7 GO:0090307 mitotic spindle assembly(GO:0090307)
0.2 2.0 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 0.9 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 0.9 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 4.9 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.2 1.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 5.1 GO:0007129 synapsis(GO:0007129)
0.2 3.7 GO:0034508 centromere complex assembly(GO:0034508)
0.2 2.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 2.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.0 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 1.6 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 2.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 9.8 GO:0007051 spindle organization(GO:0007051)
0.1 1.1 GO:0051608 histamine transport(GO:0051608)
0.1 0.7 GO:0035878 nail development(GO:0035878)
0.1 1.5 GO:0031297 replication fork processing(GO:0031297)
0.1 7.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.7 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 3.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 1.0 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 2.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 16.1 GO:0051301 cell division(GO:0051301)
0.0 1.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 4.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 1.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.3 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.1 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.6 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 28.3 GO:0031262 Ndc80 complex(GO:0031262)
3.0 18.2 GO:0070531 BRCA1-A complex(GO:0070531)
2.6 18.5 GO:0008278 cohesin complex(GO:0008278)
2.1 10.7 GO:0031523 Myb complex(GO:0031523)
2.0 10.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.2 14.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.9 5.2 GO:0044305 calyx of Held(GO:0044305)
0.8 16.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.8 7.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.7 3.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 1.5 GO:0035101 FACT complex(GO:0035101)
0.4 2.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 26.3 GO:0005882 intermediate filament(GO:0005882)
0.4 9.7 GO:0001891 phagocytic cup(GO:0001891)
0.3 3.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 4.9 GO:0005614 interstitial matrix(GO:0005614)
0.3 2.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.3 1.9 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.2 3.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 2.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 13.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.2 5.5 GO:0051233 spindle midzone(GO:0051233)
0.2 12.8 GO:0000786 nucleosome(GO:0000786)
0.2 2.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 13.1 GO:0000922 spindle pole(GO:0000922)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 2.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 4.7 GO:0090544 BAF-type complex(GO:0090544)
0.1 13.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 13.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 9.4 GO:0005814 centriole(GO:0005814)
0.1 3.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 5.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 7.3 GO:0030315 T-tubule(GO:0030315)
0.1 3.6 GO:0000793 condensed chromosome(GO:0000793)
0.1 5.3 GO:0005643 nuclear pore(GO:0005643)
0.1 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 2.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 6.0 GO:0005813 centrosome(GO:0005813)
0.0 3.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 13.6 GO:0016607 nuclear speck(GO:0016607)
0.0 13.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.4 GO:0005795 Golgi stack(GO:0005795)
0.0 3.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 4.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.9 GO:0043197 dendritic spine(GO:0043197)
0.0 4.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.8 GO:0001726 ruffle(GO:0001726)
0.0 1.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 22.3 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.3 GO:0000405 bubble DNA binding(GO:0000405)
3.2 9.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.8 11.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.7 5.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
1.5 7.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.3 10.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.3 9.1 GO:0015616 DNA translocase activity(GO:0015616)
1.2 8.7 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
1.0 3.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.9 9.4 GO:0036310 annealing helicase activity(GO:0036310)
0.7 2.9 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.7 4.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.7 2.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.6 7.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.6 2.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.6 2.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.5 19.8 GO:0050699 WW domain binding(GO:0050699)
0.5 5.4 GO:0070700 BMP receptor binding(GO:0070700)
0.5 4.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 3.4 GO:0000150 recombinase activity(GO:0000150)
0.4 14.6 GO:0070840 dynein complex binding(GO:0070840)
0.4 1.6 GO:0003883 CTP synthase activity(GO:0003883)
0.4 4.6 GO:0050693 LBD domain binding(GO:0050693)
0.4 1.9 GO:0035174 nucleosomal histone binding(GO:0031493) histone serine kinase activity(GO:0035174)
0.4 1.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 1.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.4 2.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 5.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 3.7 GO:0031996 thioesterase binding(GO:0031996)
0.3 8.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 8.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 2.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 12.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 10.1 GO:0005112 Notch binding(GO:0005112)
0.3 16.5 GO:0003684 damaged DNA binding(GO:0003684)
0.2 0.8 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.2 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 1.8 GO:0030274 LIM domain binding(GO:0030274)
0.2 5.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 1.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 5.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 19.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 2.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 3.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 14.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 1.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 4.3 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 14.8 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 5.5 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 44.2 PID_ATM_PATHWAY ATM pathway
0.5 5.4 PID_ALK2_PATHWAY ALK2 signaling events
0.5 16.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.4 20.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 8.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 7.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 5.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 13.9 PID_E2F_PATHWAY E2F transcription factor network
0.1 4.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 3.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 8.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 8.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 12.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 4.9 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.5 ST_GAQ_PATHWAY G alpha q Pathway
0.1 2.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 1.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 2.7 PID_LKB1_PATHWAY LKB1 signaling events
0.1 2.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.3 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 19.8 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.2 25.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.9 21.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.5 3.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.5 1.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 9.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 5.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5 14.1 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 2.9 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 31.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 12.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 2.9 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 1.1 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 7.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 2.0 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.8 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 5.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 5.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 10.7 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 1.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 6.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 8.7 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.1 1.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.1 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 1.5 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants