Motif ID: Ebf3

Z-value: 1.395


Transcription factors associated with Ebf3:

Gene SymbolEntrez IDGene Name
Ebf3 ENSMUSG00000010476.7 Ebf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_137314445-0.651.2e-05Click!


Activity profile for motif Ebf3.

activity profile for motif Ebf3


Sorted Z-values histogram for motif Ebf3

Sorted Z-values for motif Ebf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66812593 19.927 ENSMUST00000100572.3
Sla
src-like adaptor
chr1_-_56969827 9.660 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 9.408 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr7_+_123982799 8.626 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr8_+_70493156 7.390 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr1_-_193370260 6.074 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr5_+_117781017 6.031 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr1_-_193370225 6.024 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr1_+_75400070 5.990 ENSMUST00000113589.1
Speg
SPEG complex locus
chr15_-_98677451 5.829 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rnd1


Rho family GTPase 1


chr11_+_104231465 5.708 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr15_-_45114926 5.657 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr11_+_104231573 5.577 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr11_+_104231515 5.505 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr2_-_118703963 5.370 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr11_+_104231390 5.149 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr3_+_26331150 5.139 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr19_+_43440404 4.946 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr2_+_170731807 4.789 ENSMUST00000029075.4
Dok5
docking protein 5
chr9_-_110743653 4.778 ENSMUST00000166716.1
Pth1r
parathyroid hormone 1 receptor
chr1_-_154725920 4.773 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr4_-_149676043 4.570 ENSMUST00000118704.1
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr5_-_139129662 4.498 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr11_+_75650501 4.358 ENSMUST00000102505.3
Myo1c
myosin IC
chr5_-_139130159 4.331 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr3_+_68494208 4.268 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr7_-_4546567 4.249 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr2_-_93462386 4.054 ENSMUST00000123565.1
ENSMUST00000099696.1
Cd82

CD82 antigen

chr9_+_89909775 4.023 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr14_-_64455903 3.986 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr15_+_99224976 3.977 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr18_+_51117754 3.884 ENSMUST00000116639.2
Prr16
proline rich 16
chr4_-_129121234 3.808 ENSMUST00000030572.3
Hpca
hippocalcin
chr18_-_31447383 3.803 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr8_+_94772009 3.764 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr2_+_55437100 3.758 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr2_-_93462457 3.757 ENSMUST00000028644.4
Cd82
CD82 antigen
chr3_+_93555080 3.696 ENSMUST00000045756.7
S100a10
S100 calcium binding protein A10 (calpactin)
chr15_+_82256023 3.400 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr19_+_37550397 3.368 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr13_+_54949388 3.096 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr5_+_30711564 3.070 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5
chr11_-_98329641 3.067 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr5_+_30711849 3.026 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5

dihydropyrimidinase-like 5

chrX_+_7822289 2.922 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr4_-_129121699 2.920 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr13_-_49309217 2.912 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr12_-_109068173 2.893 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr12_-_31713873 2.878 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr11_+_75193783 2.830 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr18_-_43393346 2.777 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_+_75733037 2.727 ENSMUST00000131398.1
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr11_+_101246405 2.650 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr11_+_101246960 2.649 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr4_+_137681663 2.639 ENSMUST00000047243.5
Rap1gap
Rap1 GTPase-activating protein
chr9_-_44288131 2.611 ENSMUST00000160384.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr5_+_37245792 2.607 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1
chr19_+_58728887 2.604 ENSMUST00000048644.5
Pnliprp1
pancreatic lipase related protein 1
chr14_-_60086832 2.571 ENSMUST00000080368.5
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr4_-_155345696 2.515 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr17_+_83706170 2.473 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr4_+_57434247 2.425 ENSMUST00000102905.1
Palm2
paralemmin 2
chr7_-_4844665 2.409 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr5_+_141241490 2.407 ENSMUST00000085774.4
Sdk1
sidekick homolog 1 (chicken)
chr17_+_83706137 2.289 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3


metastasis associated 3


chr11_-_72411695 2.279 ENSMUST00000108500.1
ENSMUST00000050226.6
Smtnl2

smoothelin-like 2

chr15_-_76126538 2.175 ENSMUST00000054022.5
ENSMUST00000089654.3
BC024139

cDNA sequence BC024139

chr4_+_101496648 2.173 ENSMUST00000106930.1
ENSMUST00000154120.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr19_+_4231899 2.162 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr2_+_178414512 2.134 ENSMUST00000094251.4
Fam217b
family with sequence similarity 217, member B
chr7_+_45785331 2.122 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr3_+_145987835 2.106 ENSMUST00000039517.6
Syde2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr6_-_32588192 2.090 ENSMUST00000115096.2
Plxna4
plexin A4
chr6_+_58831748 2.089 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr7_+_28982832 2.070 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr5_+_117363513 2.070 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr2_+_55435918 2.030 ENSMUST00000067101.3
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr11_+_83409137 2.025 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chr7_-_68749170 1.991 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr11_+_83409655 1.982 ENSMUST00000175848.1
ENSMUST00000108140.3
Rasl10b

RAS-like, family 10, member B

chr5_-_38159457 1.981 ENSMUST00000031009.4
Nsg1
neuron specific gene family member 1
chr13_+_30659999 1.975 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
Dusp22


dual specificity phosphatase 22


chr18_+_61105561 1.924 ENSMUST00000025523.6
Csf1r
colony stimulating factor 1 receptor
chr15_+_78913916 1.893 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr17_-_24644933 1.884 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_-_90580578 1.866 ENSMUST00000168621.2
Ptprj
protein tyrosine phosphatase, receptor type, J
chr12_+_82170016 1.800 ENSMUST00000166429.1
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr10_-_127060163 1.796 ENSMUST00000040307.5
March9
membrane-associated ring finger (C3HC4) 9
chr5_-_37824580 1.739 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr1_-_173367638 1.711 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr14_-_41013753 1.695 ENSMUST00000143143.1
ENSMUST00000128236.1
ENSMUST00000022317.8
ENSMUST00000118466.1
Fam213a



family with sequence similarity 213, member A



chr7_+_49975228 1.670 ENSMUST00000107603.1
Nell1
NEL-like 1
chr6_-_124464772 1.652 ENSMUST00000008297.4
Clstn3
calsyntenin 3
chr18_+_38418946 1.626 ENSMUST00000025293.3
Ndfip1
Nedd4 family interacting protein 1
chr5_-_24601961 1.608 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr3_+_88043098 1.566 ENSMUST00000166021.1
ENSMUST00000029707.7
Gpatch4

G patch domain containing 4

chr18_+_36348739 1.557 ENSMUST00000152804.2
Cystm1
cysteine-rich transmembrane module containing 1
chr2_+_30441831 1.541 ENSMUST00000131476.1
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr14_-_61037937 1.538 ENSMUST00000111236.2
Tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr10_-_41303171 1.522 ENSMUST00000043814.3
Fig4
FIG4 homolog (S. cerevisiae)
chr9_-_64022043 1.480 ENSMUST00000041029.5
Smad6
SMAD family member 6
chr6_-_119848093 1.451 ENSMUST00000079582.4
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr11_-_97744659 1.432 ENSMUST00000018691.8
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr17_-_48451510 1.423 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr10_+_116143881 1.421 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chrX_-_101419788 1.414 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr16_-_65562686 1.410 ENSMUST00000004965.6
Chmp2b
charged multivesicular body protein 2B
chr6_+_56832059 1.396 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9
chr9_+_45117813 1.395 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr7_-_24587612 1.346 ENSMUST00000094705.2
Zfp575
zinc finger protein 575
chr17_+_44777294 1.335 ENSMUST00000127798.1
Supt3
suppressor of Ty 3
chr6_+_110645572 1.324 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr8_+_71469186 1.316 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr10_+_80299084 1.314 ENSMUST00000154212.1
Apc2
adenomatosis polyposis coli 2
chr13_-_18031616 1.313 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr3_+_97158767 1.308 ENSMUST00000090759.4
Acp6
acid phosphatase 6, lysophosphatidic
chr4_+_117835387 1.274 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_-_79743034 1.251 ENSMUST00000032761.7
Pex11a
peroxisomal biogenesis factor 11 alpha
chr5_+_76140700 1.244 ENSMUST00000152642.1
ENSMUST00000127278.1
Srd5a3

steroid 5 alpha-reductase 3

chr5_+_73292794 1.226 ENSMUST00000031038.4
ENSMUST00000071081.6
ENSMUST00000166823.1
Ociad1


OCIA domain containing 1


chr16_+_30065333 1.213 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chrX_-_101420348 1.195 ENSMUST00000119699.1
Zmym3
zinc finger, MYM-type 3
chr19_-_45816007 1.185 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
Kcnip2


Kv channel-interacting protein 2


chrX_-_101420206 1.129 ENSMUST00000118092.1
Zmym3
zinc finger, MYM-type 3
chr1_+_89454769 1.127 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr9_+_121760000 1.108 ENSMUST00000093772.3
Zfp651
zinc finger protein 651
chr4_+_114680769 1.099 ENSMUST00000146346.1
Gm12829
predicted gene 12829
chr19_+_46341118 1.096 ENSMUST00000128041.1
Tmem180
transmembrane protein 180
chr15_+_89499598 1.044 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr11_+_75732869 1.038 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr15_+_102102926 1.032 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr2_-_32260138 1.025 ENSMUST00000002625.8
Uck1
uridine-cytidine kinase 1
chr19_-_47464406 1.009 ENSMUST00000111800.2
ENSMUST00000081619.2
Sh3pxd2a

SH3 and PX domains 2A

chr4_+_130915949 1.006 ENSMUST00000030316.6
Laptm5
lysosomal-associated protein transmembrane 5
chr6_-_119848059 1.003 ENSMUST00000184864.1
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr10_+_80329953 0.993 ENSMUST00000105358.1
ENSMUST00000105357.1
ENSMUST00000105354.1
ENSMUST00000105355.1
Reep6



receptor accessory protein 6



chr7_-_25297866 0.986 ENSMUST00000148150.1
ENSMUST00000155118.1
Pafah1b3

platelet-activating factor acetylhydrolase, isoform 1b, subunit 3

chr1_-_36709904 0.984 ENSMUST00000043951.3
Actr1b
ARP1 actin-related protein 1B, centractin beta
chr7_+_24587543 0.969 ENSMUST00000077191.6
Ethe1
ethylmalonic encephalopathy 1
chr1_+_176814660 0.969 ENSMUST00000056773.8
ENSMUST00000027785.8
Sdccag8

serologically defined colon cancer antigen 8

chr6_+_142413441 0.967 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr9_+_30942541 0.965 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr5_-_142509653 0.960 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chr9_-_103228420 0.934 ENSMUST00000126359.1
Trf
transferrin
chr11_-_29825649 0.932 ENSMUST00000104962.1
4931440F15Rik
RIKEN cDNA 4931440F15 gene
chr19_-_10869757 0.919 ENSMUST00000120524.1
ENSMUST00000025645.7
Tmem132a

transmembrane protein 132A

chr18_+_36348653 0.913 ENSMUST00000050584.3
Cystm1
cysteine-rich transmembrane module containing 1
chr4_+_43957678 0.904 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr1_+_74284930 0.890 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr2_+_121956651 0.887 ENSMUST00000110574.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr9_+_31280525 0.882 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr3_-_41082992 0.881 ENSMUST00000058578.7
Pgrmc2
progesterone receptor membrane component 2
chr19_-_5610038 0.877 ENSMUST00000113641.2
Kat5
K(lysine) acetyltransferase 5
chr7_-_110061319 0.873 ENSMUST00000098110.2
AA474408
expressed sequence AA474408
chr7_-_45510315 0.869 ENSMUST00000131589.1
ENSMUST00000132875.1
Nucb1

nucleobindin 1

chr17_-_50094277 0.868 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr9_+_21015960 0.854 ENSMUST00000086399.4
Icam1
intercellular adhesion molecule 1
chr7_+_126649297 0.846 ENSMUST00000032956.8
Ccdc101
coiled-coil domain containing 101
chr4_-_148130678 0.839 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr4_-_152038568 0.836 ENSMUST00000030792.1
Tas1r1
taste receptor, type 1, member 1
chr17_-_34121944 0.832 ENSMUST00000151986.1
Brd2
bromodomain containing 2
chr1_+_195017399 0.824 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr7_-_45510400 0.815 ENSMUST00000033096.7
Nucb1
nucleobindin 1
chr18_+_31634374 0.812 ENSMUST00000025109.7
Sap130
Sin3A associated protein
chr3_+_90072641 0.795 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr4_+_43957401 0.789 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr19_+_41981709 0.783 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr18_+_31634368 0.781 ENSMUST00000178164.1
Sap130
Sin3A associated protein
chr11_-_120378692 0.779 ENSMUST00000026448.9
2310003H01Rik
RIKEN cDNA 2310003H01 gene
chr7_-_100932140 0.774 ENSMUST00000107032.1
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr4_+_141147911 0.774 ENSMUST00000030757.9
Fbxo42
F-box protein 42
chr12_-_76962178 0.767 ENSMUST00000110395.3
ENSMUST00000082136.5
Max

Max protein

chr11_-_94474088 0.765 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr19_-_7483241 0.759 ENSMUST00000025667.6
ENSMUST00000065304.5
ENSMUST00000088171.4
Rtn3


reticulon 3


chrX_+_7638674 0.754 ENSMUST00000128890.1
Syp
synaptophysin
chrX_+_56787701 0.752 ENSMUST00000151033.1
Fhl1
four and a half LIM domains 1
chr8_+_106150359 0.746 ENSMUST00000034377.6
Pla2g15
phospholipase A2, group XV
chr2_-_52558539 0.745 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr8_+_113635787 0.740 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr6_+_91473695 0.738 ENSMUST00000032183.4
Tmem43
transmembrane protein 43
chr5_-_62765618 0.728 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_135078224 0.696 ENSMUST00000067935.4
ENSMUST00000076203.2
Vps37d

vacuolar protein sorting 37D (yeast)

chr11_-_95699143 0.690 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr14_-_69503316 0.690 ENSMUST00000179116.2
Gm21464
predicted gene, 21464
chr15_-_100424208 0.674 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr6_-_119848120 0.670 ENSMUST00000183703.1
ENSMUST00000183911.1
Erc1

ELKS/RAB6-interacting/CAST family member 1

chr17_-_36951636 0.663 ENSMUST00000040402.7
ENSMUST00000174711.1
Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr11_+_101316200 0.659 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chrX_+_82948861 0.651 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr6_+_124663027 0.650 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr17_-_36951338 0.648 ENSMUST00000173540.1
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr19_-_7483212 0.644 ENSMUST00000088169.5
Rtn3
reticulon 3
chr3_+_115888139 0.636 ENSMUST00000106505.1
ENSMUST00000043342.9
Dph5

DPH5 homolog (S. cerevisiae)

chr15_+_85336350 0.630 ENSMUST00000163242.1
Atxn10
ataxin 10
chr19_+_11518493 0.626 ENSMUST00000025580.3
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr15_-_98165560 0.623 ENSMUST00000123922.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr9_-_110117303 0.616 ENSMUST00000136969.1
Dhx30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr3_-_107760221 0.614 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr11_-_69837781 0.607 ENSMUST00000108634.2
Nlgn2
neuroligin 2
chr17_-_46032366 0.606 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 21.9 GO:1900034 regulation of cellular response to heat(GO:1900034)
2.2 6.7 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
2.0 6.0 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
1.2 7.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.2 19.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.0 3.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.0 4.8 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.9 3.8 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.9 5.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.9 4.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.8 5.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.8 1.6 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.8 3.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.7 8.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.7 4.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 2.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 4.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.7 2.6 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.6 2.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.6 1.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.5 1.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.5 2.1 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.5 1.0 GO:0003169 coronary vein morphogenesis(GO:0003169)
0.5 2.5 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.5 4.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.5 3.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.5 1.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.5 0.9 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.5 2.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.4 1.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 1.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.4 4.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.4 3.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 1.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.4 2.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 1.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 1.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 2.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.3 4.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.3 1.4 GO:0046684 response to pyrethroid(GO:0046684)
0.3 1.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.3 0.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.3 4.3 GO:0001553 luteinization(GO:0001553)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 1.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 2.0 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.2 1.5 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 0.7 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 5.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.2 4.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.2 1.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 1.0 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.2 1.0 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 1.0 GO:0072675 osteoclast fusion(GO:0072675)
0.2 0.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 2.8 GO:0016322 neuron remodeling(GO:0016322)
0.2 3.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 1.7 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.2 4.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2 12.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.8 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.2 0.5 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.2 GO:0070627 ferrous iron import(GO:0070627)
0.2 4.0 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.2 3.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 2.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.3 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 1.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 4.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.9 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.1 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 2.4 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 1.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 2.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 3.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.3 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 1.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 12.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.2 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 6.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 2.6 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.6 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 0.4 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.1 1.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.3 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 1.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.3 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 1.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 1.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.5 GO:0097435 fibril organization(GO:0097435)
0.0 2.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0032060 bleb assembly(GO:0032060)
0.0 0.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 4.3 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.8 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 2.7 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.0 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 1.1 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.2 GO:0030010 establishment of cell polarity(GO:0030010)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
2.2 21.9 GO:0045298 tubulin complex(GO:0045298)
1.5 4.4 GO:0045160 myosin I complex(GO:0045160)
1.1 4.2 GO:1990769 proximal neuron projection(GO:1990769)
1.1 5.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.8 2.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 2.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.7 8.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 6.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.5 6.7 GO:0044327 dendritic spine head(GO:0044327)
0.4 2.5 GO:0045179 apical cortex(GO:0045179)
0.3 1.1 GO:0008537 proteasome activator complex(GO:0008537)
0.3 1.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 3.8 GO:0031045 dense core granule(GO:0031045)
0.2 1.0 GO:0070826 paraferritin complex(GO:0070826)
0.2 4.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 3.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 3.4 GO:0000145 exocyst(GO:0000145)
0.2 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.0 GO:0098845 postsynaptic endosome(GO:0098845)
0.2 3.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 15.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 6.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 6.4 GO:0031941 filamentous actin(GO:0031941)
0.1 1.9 GO:0070938 contractile ring(GO:0070938)
0.1 1.1 GO:0097433 dense body(GO:0097433)
0.1 19.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 10.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 3.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 2.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:0070552 BRISC complex(GO:0070552)
0.1 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.0 GO:0005869 dynactin complex(GO:0005869)
0.1 3.9 GO:0031526 brush border membrane(GO:0031526)
0.1 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 2.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 2.8 GO:0005871 kinesin complex(GO:0005871)
0.0 2.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 5.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.8 GO:0005795 Golgi stack(GO:0005795)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 7.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 12.7 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 21.9 GO:0099609 microtubule lateral binding(GO:0099609)
2.0 6.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.3 4.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.2 5.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.1 7.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.1 5.3 GO:0097643 amylin receptor activity(GO:0097643)
1.0 3.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.8 4.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.8 8.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.8 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.7 4.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.7 2.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.6 5.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.6 4.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.5 3.1 GO:0005042 netrin receptor activity(GO:0005042)
0.5 19.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.5 1.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 1.9 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.4 1.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 1.3 GO:0070905 serine binding(GO:0070905)
0.4 1.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4 5.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 3.8 GO:0050815 phosphoserine binding(GO:0050815)
0.3 1.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3 12.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.3 1.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 2.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 2.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 1.5 GO:0070697 activin receptor binding(GO:0070697)
0.2 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 1.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 4.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 2.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.9 GO:0070097 delta-catenin binding(GO:0070097)
0.2 4.5 GO:0017046 peptide hormone binding(GO:0017046)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 3.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 3.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.2 GO:0031005 filamin binding(GO:0031005)
0.1 1.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 4.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.1 2.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 3.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 3.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.0 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 4.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 3.1 GO:0008201 heparin binding(GO:0008201)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0005496 steroid binding(GO:0005496)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.8 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 1.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 10.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 4.1 GO:0003924 GTPase activity(GO:0003924)
0.0 3.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.9 GO:0042277 peptide binding(GO:0042277)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 21.9 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 5.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 2.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 10.4 ST_ADRENERGIC Adrenergic Pathway
0.2 25.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.2 5.5 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 1.0 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 4.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.5 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 3.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.6 PID_MYC_PATHWAY C-MYC pathway
0.1 10.0 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 3.4 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 4.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.5 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.2 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.4 PID_RB_1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.7 15.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 11.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 8.8 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 3.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 1.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 8.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 2.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 6.0 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 7.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 10.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 6.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 2.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 5.8 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 3.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 3.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 3.1 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 2.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.2 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.7 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 1.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.8 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins