Motif ID: Elf3

Z-value: 0.998


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.271.0e-01Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_169685191 5.581 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr4_-_53159885 5.062 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr5_+_17574268 4.898 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_83648713 4.329 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr19_+_5740885 3.714 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr17_+_35049966 3.528 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr14_-_70207637 3.290 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr13_-_103920508 3.084 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr1_+_138963709 2.974 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr12_-_65172560 2.945 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr3_-_52104891 2.933 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr11_+_115163333 2.816 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr1_-_128592284 2.768 ENSMUST00000052172.6
ENSMUST00000142893.1
Cxcr4

chemokine (C-X-C motif) receptor 4

chr7_-_102250086 2.708 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr13_-_103920295 2.552 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr15_+_55557399 2.326 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr10_-_83648631 2.040 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr14_-_57890242 2.009 ENSMUST00000089473.3
Zdhhc20
zinc finger, DHHC domain containing 20
chr5_-_43981757 1.907 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr9_+_91368811 1.877 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr11_+_61653259 1.806 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr3_-_84582476 1.768 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr9_-_66919646 1.734 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr3_-_146499721 1.641 ENSMUST00000029839.4
Spata1
spermatogenesis associated 1
chr16_+_92498122 1.635 ENSMUST00000023670.3
Clic6
chloride intracellular channel 6
chr14_+_25983005 1.604 ENSMUST00000049793.8
Duxbl1
double homeobox B-like 1
chr16_+_62854299 1.554 ENSMUST00000023629.8
Pros1
protein S (alpha)
chr11_-_55419898 1.534 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr15_+_55557575 1.527 ENSMUST00000170046.1
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr6_+_29694204 1.486 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr1_+_136467958 1.485 ENSMUST00000047817.6
Kif14
kinesin family member 14
chrX_+_142226765 1.438 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr14_-_20496780 1.399 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr11_-_100850724 1.391 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr4_+_44756553 1.344 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr6_-_48708206 1.323 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr18_-_62756275 1.309 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr5_-_30155101 1.291 ENSMUST00000156859.1
Hadha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
chr7_+_27486910 1.288 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr14_+_34673888 1.277 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr17_+_86753900 1.265 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr4_-_118489755 1.250 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr19_-_50678642 1.235 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr2_+_164562579 1.223 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr18_+_56432116 1.205 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr4_-_63403330 1.167 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr7_-_143740316 1.161 ENSMUST00000119499.1
Osbpl5
oxysterol binding protein-like 5
chr2_+_31470207 1.148 ENSMUST00000102840.4
Ass1
argininosuccinate synthetase 1
chr8_+_104340594 1.148 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr16_-_44016387 1.137 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr10_+_83543941 1.116 ENSMUST00000038388.5
A230046K03Rik
RIKEN cDNA A230046K03 gene
chr10_-_62231208 1.084 ENSMUST00000047883.9
Tspan15
tetraspanin 15
chr6_+_115134899 1.071 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr10_-_30655859 1.045 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr11_+_53770014 1.041 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr3_-_122984404 1.026 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr1_-_161876656 0.987 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr7_-_142666816 0.972 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr8_+_66386292 0.950 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr12_-_69357120 0.946 ENSMUST00000021368.8
Nemf
nuclear export mediator factor
chr3_+_90603767 0.943 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr17_+_86963279 0.942 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr7_+_101378183 0.937 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr13_+_63282142 0.930 ENSMUST00000159152.1
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr15_-_89170688 0.929 ENSMUST00000060808.9
Plxnb2
plexin B2
chr3_-_116614587 0.926 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr15_+_79516396 0.922 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr11_-_118401826 0.913 ENSMUST00000106290.3
ENSMUST00000043722.3
Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr1_+_84839833 0.909 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr10_-_89443888 0.909 ENSMUST00000099374.2
ENSMUST00000105298.1
Gas2l3

growth arrest-specific 2 like 3

chr3_-_127780461 0.901 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr6_+_15720654 0.900 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr1_+_58795371 0.891 ENSMUST00000027189.8
Casp8
caspase 8
chr14_-_8309770 0.883 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr6_+_15721087 0.857 ENSMUST00000120512.1
Mdfic
MyoD family inhibitor domain containing
chr19_+_20601958 0.855 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chrX_+_68821093 0.847 ENSMUST00000096420.2
Gm14698
predicted gene 14698
chr15_-_78803015 0.845 ENSMUST00000164826.1
Card10
caspase recruitment domain family, member 10
chr6_-_86793522 0.834 ENSMUST00000001187.8
Anxa4
annexin A4
chr9_-_116175318 0.831 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr1_-_75264195 0.824 ENSMUST00000027404.5
Ptprn
protein tyrosine phosphatase, receptor type, N
chr7_+_12478293 0.823 ENSMUST00000098822.3
Zfp606
zinc finger protein 606
chr6_+_48739039 0.823 ENSMUST00000054368.4
ENSMUST00000140054.1
Gimap1

GTPase, IMAP family member 1

chr2_-_72980402 0.818 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3

trans-acting transcription factor 3

chr8_+_72646679 0.815 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr17_-_25880236 0.813 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr5_+_110330697 0.797 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr3_+_89418443 0.793 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chrX_+_161717498 0.789 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr5_+_90931196 0.785 ENSMUST00000071652.4
Mthfd2l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr4_-_40722307 0.785 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr14_-_31830402 0.783 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr8_-_71395794 0.780 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr8_+_72646728 0.769 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr5_+_108065742 0.750 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr1_-_4496363 0.749 ENSMUST00000116652.2
Sox17
SRY-box containing gene 17
chr2_+_31572651 0.748 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr11_-_106388066 0.746 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr7_-_101933815 0.744 ENSMUST00000106963.1
ENSMUST00000106966.1
Lrrc51

leucine rich repeat containing 51

chr11_+_53770458 0.732 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr11_-_48816936 0.720 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr7_-_128298081 0.720 ENSMUST00000033044.9
BC017158
cDNA sequence BC017158
chr4_-_11965699 0.712 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr11_+_78324200 0.698 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr3_+_146499850 0.697 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr14_-_54577578 0.697 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr5_-_142608785 0.688 ENSMUST00000037048.7
Mmd2
monocyte to macrophage differentiation-associated 2
chr1_-_155527083 0.688 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr1_+_58802492 0.685 ENSMUST00000165549.1
Casp8
caspase 8
chr3_-_89418287 0.683 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr11_-_17008647 0.650 ENSMUST00000102881.3
Plek
pleckstrin
chr7_+_102065713 0.646 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr11_-_103344651 0.641 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr13_-_55100248 0.641 ENSMUST00000026997.5
ENSMUST00000127195.1
ENSMUST00000099496.3
Uimc1


ubiquitin interaction motif containing 1


chr9_+_14276301 0.638 ENSMUST00000034507.7
Sesn3
sestrin 3
chr6_+_71272019 0.635 ENSMUST00000168700.1
Krcc1
lysine-rich coiled-coil 1
chr14_+_34673948 0.631 ENSMUST00000090027.3
Wapal
wings apart-like homolog (Drosophila)
chr6_-_24515036 0.629 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr3_+_146499828 0.623 ENSMUST00000090031.5
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr6_-_146502141 0.619 ENSMUST00000079573.6
ENSMUST00000139732.1
Itpr2

inositol 1,4,5-triphosphate receptor 2

chr7_-_25477607 0.618 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chrX_-_75578188 0.617 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr1_-_84839304 0.617 ENSMUST00000027421.6
Trip12
thyroid hormone receptor interactor 12
chr1_-_121328024 0.614 ENSMUST00000003818.7
Insig2
insulin induced gene 2
chr19_+_46305682 0.606 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr1_+_15805639 0.602 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr3_+_95160449 0.590 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr1_-_121327734 0.579 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr17_+_21733704 0.575 ENSMUST00000183192.1
ENSMUST00000065871.7
Zfp229

zinc finger protein 229

chr1_-_4496400 0.572 ENSMUST00000027035.3
Sox17
SRY-box containing gene 17
chr17_+_31057686 0.561 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr2_+_131491958 0.560 ENSMUST00000110181.1
ENSMUST00000110180.1
Smox

spermine oxidase

chr1_+_36307745 0.552 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr7_-_80324418 0.545 ENSMUST00000047362.4
ENSMUST00000121882.1
Rccd1

RCC1 domain containing 1

chr2_-_105904484 0.545 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr14_+_34674122 0.539 ENSMUST00000169910.1
Wapal
wings apart-like homolog (Drosophila)
chr9_-_54647199 0.539 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr7_-_101933780 0.537 ENSMUST00000106964.1
ENSMUST00000078448.3
Lrrc51

leucine rich repeat containing 51

chr5_+_43672289 0.534 ENSMUST00000156034.1
Cc2d2a
coiled-coil and C2 domain containing 2A
chr7_-_80232479 0.524 ENSMUST00000123279.1
Cib1
calcium and integrin binding 1 (calmyrin)
chr7_+_130865835 0.524 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr3_+_103279293 0.522 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr5_+_64159429 0.512 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr11_-_48817332 0.511 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr2_+_131491764 0.510 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr15_-_83432819 0.502 ENSMUST00000165095.1
Pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr13_+_13437602 0.495 ENSMUST00000005532.7
Nid1
nidogen 1
chr9_-_109059216 0.486 ENSMUST00000112053.1
Trex1
three prime repair exonuclease 1
chr5_+_115845229 0.483 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr13_+_44729794 0.477 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr6_-_97459279 0.476 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr6_+_119175247 0.469 ENSMUST00000112777.2
ENSMUST00000073909.5
Dcp1b

DCP1 decapping enzyme homolog B (S. cerevisiae)

chr18_-_3281036 0.469 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr1_-_13589717 0.467 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr1_-_121327672 0.445 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr2_+_26581050 0.443 ENSMUST00000166920.2
Egfl7
EGF-like domain 7
chr19_-_50678485 0.442 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr13_+_44729535 0.439 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr7_+_102065485 0.430 ENSMUST00000106950.1
ENSMUST00000146450.1
Trpc2

transient receptor potential cation channel, subfamily C, member 2

chr11_+_51261719 0.414 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr13_-_107414742 0.412 ENSMUST00000061241.6
Apoo-ps
apolipoprotein O, pseudogene
chrX_-_8090442 0.403 ENSMUST00000033505.6
Was
Wiskott-Aldrich syndrome homolog (human)
chr19_-_5912834 0.401 ENSMUST00000136983.1
Dpf2
D4, zinc and double PHD fingers family 2
chr9_-_108578657 0.397 ENSMUST00000068700.5
Wdr6
WD repeat domain 6
chr3_-_51396528 0.392 ENSMUST00000038154.5
Mgarp
mitochondria localized glutamic acid rich protein
chr2_-_73580288 0.379 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr1_-_121327776 0.377 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr1_+_170308802 0.373 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr2_+_165055625 0.370 ENSMUST00000017799.5
ENSMUST00000073707.2
Cd40

CD40 antigen

chr7_+_119794102 0.363 ENSMUST00000084644.2
2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr17_+_8311101 0.361 ENSMUST00000154553.1
Sft2d1
SFT2 domain containing 1
chr19_-_5912771 0.359 ENSMUST00000118623.1
Dpf2
D4, zinc and double PHD fingers family 2
chr2_-_148045891 0.354 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr5_-_143180721 0.351 ENSMUST00000164068.1
ENSMUST00000049861.4
ENSMUST00000165318.1
Rbak


RB-associated KRAB repressor


chr1_-_161131428 0.349 ENSMUST00000111611.1
Klhl20
kelch-like 20
chr3_+_87919490 0.345 ENSMUST00000019854.6
ENSMUST00000119968.1
Mrpl24

mitochondrial ribosomal protein L24

chr12_+_65075582 0.345 ENSMUST00000058889.4
Fancm
Fanconi anemia, complementation group M
chr9_+_35559460 0.344 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr11_+_117232254 0.333 ENSMUST00000106354.2
Sept9
septin 9
chr18_-_38338997 0.327 ENSMUST00000063814.8
Gnpda1
glucosamine-6-phosphate deaminase 1
chr6_-_146502099 0.321 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr10_+_80249441 0.319 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr9_-_20898592 0.315 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr7_+_119793987 0.310 ENSMUST00000033218.8
ENSMUST00000106520.1
2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr3_-_51396502 0.305 ENSMUST00000108046.1
Mgarp
mitochondria localized glutamic acid rich protein
chr10_+_80249106 0.299 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr9_-_43116514 0.294 ENSMUST00000061833.4
Tmem136
transmembrane protein 136
chr5_-_105343929 0.291 ENSMUST00000183149.1
Gbp11
guanylate binding protein 11
chr19_-_33590308 0.291 ENSMUST00000112508.2
Lipo1
lipase, member O1
chr7_-_3677509 0.282 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr9_-_109059711 0.280 ENSMUST00000061973.4
Trex1
three prime repair exonuclease 1
chr6_-_23248264 0.280 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr19_+_8850785 0.271 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr3_+_87919563 0.264 ENSMUST00000121920.1
Mrpl24
mitochondrial ribosomal protein L24
chr4_-_106464167 0.263 ENSMUST00000049507.5
Pcsk9
proprotein convertase subtilisin/kexin type 9
chr2_+_126215100 0.255 ENSMUST00000164042.2
Gm17555
predicted gene, 17555
chr1_+_51987139 0.255 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr8_+_123065476 0.248 ENSMUST00000153285.1
Spg7
spastic paraplegia 7 homolog (human)
chr11_-_78080360 0.245 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chr6_+_122308684 0.242 ENSMUST00000007602.8
ENSMUST00000112610.1
M6pr

mannose-6-phosphate receptor, cation dependent


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0055099 response to high density lipoprotein particle(GO:0055099)
1.2 3.7 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.9 2.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.8 4.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.8 3.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.7 2.8 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.6 5.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.6 1.8 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.5 1.4 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.4 3.5 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743)
0.4 1.3 GO:0060913 stem cell fate specification(GO:0048866) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043)
0.4 1.5 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.3 0.6 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.3 1.1 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.3 0.8 GO:0003274 endocardial cushion fusion(GO:0003274)
0.3 2.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 0.8 GO:0045004 DNA replication proofreading(GO:0045004)
0.3 1.3 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.2 1.7 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 1.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.1 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.2 1.1 GO:0046208 spermine catabolic process(GO:0046208)
0.2 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.6 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 0.8 GO:0006547 histidine metabolic process(GO:0006547)
0.2 1.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.5 GO:2000256 positive regulation of male germ cell proliferation(GO:2000256)
0.2 1.6 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.6 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.2 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 0.8 GO:1990839 response to endothelin(GO:1990839)
0.2 0.6 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.1 0.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 2.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.4 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.8 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.5 GO:0070836 caveola assembly(GO:0070836)
0.1 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 5.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.3 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0046370 fructose biosynthetic process(GO:0046370)
0.1 0.2 GO:2000338 positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.0 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 1.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:0002467 germinal center formation(GO:0002467)
0.0 0.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.9 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:0030049 diaphragm contraction(GO:0002086) muscle filament sliding(GO:0030049)
0.0 0.2 GO:0042891 antibiotic transport(GO:0042891)
0.0 1.2 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.8 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.5 GO:0051591 response to cAMP(GO:0051591)
0.0 0.5 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.6 GO:0007411 axon guidance(GO:0007411)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.4 1.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.4 1.3 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.4 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 2.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 5.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 6.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 2.8 GO:0032426 stereocilium tip(GO:0032426)
0.3 2.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 2.9 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 5.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.1 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.7 GO:0051286 cell tip(GO:0051286)
0.1 6.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.6 GO:0070187 telosome(GO:0070187)
0.1 2.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.6 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 3.3 GO:0000776 kinetochore(GO:0000776)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 8.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0001726 ruffle(GO:0001726)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 3.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.9 2.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 1.6 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.4 1.6 GO:0035877 death effector domain binding(GO:0035877)
0.4 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.4 1.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.3 1.3 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 0.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 0.8 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 1.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 0.9 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 1.7 GO:0030911 TPR domain binding(GO:0030911)
0.2 2.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 0.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.8 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.6 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.2 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 3.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 2.3 GO:0017166 vinculin binding(GO:0017166)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.3 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125) Toll-like receptor binding(GO:0035325)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0019961 interferon binding(GO:0019961)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 2.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 5.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 4.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.8 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.1 1.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 2.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 0.8 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 6.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.8 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 5.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.4 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.2 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.4 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 1.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 0.9 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.2 2.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 0.9 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.8 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 1.4 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.6 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.9 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.7 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.1 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.8 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease