Motif ID: Elf5

Z-value: 0.616


Transcription factors associated with Elf5:

Gene SymbolEntrez IDGene Name
Elf5 ENSMUSG00000027186.8 Elf5



Activity profile for motif Elf5.

activity profile for motif Elf5


Sorted Z-values histogram for motif Elf5

Sorted Z-values for motif Elf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_22689771 2.006 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr6_-_23248264 1.370 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr14_-_76556662 1.131 ENSMUST00000064517.7
 Serp2
stress-associated endoplasmic reticulum protein family member 2
chr3_+_95526777 1.094 ENSMUST00000015667.2
ENSMUST00000116304.2
 Ctss

cathepsin S

chr11_+_111066154 1.002 ENSMUST00000042970.2
 Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_136886187 0.979 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr12_+_77238093 0.952 ENSMUST00000177595.1
ENSMUST00000171770.2
 Fut8

fucosyltransferase 8

chr17_-_33940299 0.907 ENSMUST00000173363.1
ENSMUST00000174048.1
ENSMUST00000179418.1
ENSMUST00000174426.1
ENSMUST00000025163.7
 H2-Ke2




H2-K region expressed gene 2




chr6_-_8259098 0.856 ENSMUST00000012627.4
 Rpa3
replication protein A3
chr9_-_77347816 0.781 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr11_-_53430417 0.779 ENSMUST00000109019.1
 Uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr9_-_39603635 0.770 ENSMUST00000119722.1
 AW551984
expressed sequence AW551984
chr13_-_92030897 0.767 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr12_+_84970897 0.754 ENSMUST00000021669.8
ENSMUST00000171040.1
 Fcf1

FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)

chr10_+_83722865 0.742 ENSMUST00000150459.1
 1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr6_-_72390659 0.732 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr12_+_112760652 0.716 ENSMUST00000063888.3
 Pld4
phospholipase D family, member 4
chr5_+_145114280 0.703 ENSMUST00000141602.1
 Arpc1b
actin related protein 2/3 complex, subunit 1B
chr14_-_55671873 0.700 ENSMUST00000163750.1
ENSMUST00000010520.8
 Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr2_-_120154600 0.685 ENSMUST00000028755.7
 Ehd4
EH-domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 371 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 3.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 2.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.8 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 1.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.6 GO:0010447 response to acidic pH(GO:0010447)
0.5 1.5 GO:0051715 cytolysis in other organism(GO:0051715)
0.2 1.4 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.2 1.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 1.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.4 1.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.2 1.1 GO:0021539 subthalamus development(GO:0021539)
0.1 1.1 GO:0016093 polyprenol metabolic process(GO:0016093)
0.3 1.0 GO:0019043 establishment of viral latency(GO:0019043)
0.2 1.0 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 206 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 5.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 3.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 3.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 2.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.5 GO:0005687 U4 snRNP(GO:0005687)
0.0 2.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)
0.1 1.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 1.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 1.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 253 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.8 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.2 GO:0043236 laminin binding(GO:0043236)
0.1 1.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 1.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 1.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 2.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID_P73PATHWAY p73 transcription factor network
0.0 1.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.4 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.1 0.9 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.7 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.6 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.5 SIG_CHEMOTAXIS Genes related to chemotaxis

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 5.0 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 4.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 4.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 2.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.2 1.8 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.7 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.2 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4 1.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.1 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 1.0 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.0 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.9 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.8 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor