Motif ID: Emx1_Emx2

Z-value: 0.494

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx1mm10_v2_chr6_+_85187438_851875100.221.9e-01Click!
Emx2mm10_v2_chr19_+_59458372_594584500.105.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_118961578 3.231 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr4_-_82505274 2.127 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr4_-_82505749 2.077 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr3_+_127633134 1.661 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr4_-_82505707 1.658 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr7_-_103827922 1.603 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr17_-_36032682 1.322 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr2_-_160619971 1.293 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr12_-_98577940 1.074 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr13_-_97747373 1.056 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chrX_+_106920618 1.053 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr7_+_126781483 1.012 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr17_-_31636631 0.957 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr13_-_97747399 0.954 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_+_90541146 0.905 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr8_-_21906412 0.841 ENSMUST00000051965.4
Defb11
defensin beta 11
chr3_-_49757257 0.818 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr5_-_28210022 0.818 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr18_+_57142782 0.806 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr10_+_90071095 0.722 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr6_-_57535422 0.717 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr11_+_109543694 0.697 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr6_+_42245907 0.681 ENSMUST00000031897.5
Gstk1
glutathione S-transferase kappa 1
chr1_-_144177259 0.665 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr3_-_63851251 0.664 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr14_+_26259109 0.657 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr6_-_101377342 0.634 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr8_+_69300776 0.610 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr18_-_15403680 0.610 ENSMUST00000079081.6
Aqp4
aquaporin 4
chrM_+_11734 0.533 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr10_-_25297055 0.532 ENSMUST00000177124.1
Akap7
A kinase (PRKA) anchor protein 7
chrX_+_8271133 0.517 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr7_-_142661858 0.517 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr2_+_175469985 0.512 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr14_+_46832127 0.510 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr10_-_42583628 0.493 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr4_+_110397661 0.492 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr16_-_63864114 0.492 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr10_+_79996479 0.483 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr9_+_65890237 0.480 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr8_-_4779513 0.474 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr3_+_137341103 0.467 ENSMUST00000119475.1
Emcn
endomucin
chr13_+_23763660 0.448 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr14_+_25980039 0.444 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr9_+_72958785 0.441 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr2_-_175703646 0.434 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chr2_+_175372436 0.415 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chr14_+_25979401 0.404 ENSMUST00000173580.1
Duxbl1
double homeobox B-like 1
chr16_-_44016387 0.398 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr4_+_110397764 0.395 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr14_+_26119811 0.394 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr14_+_26119173 0.372 ENSMUST00000174564.1
Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 0.372 ENSMUST00000172517.1
Duxbl3
double homeobox B-like 3
chr15_-_103366763 0.363 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr12_-_90969768 0.359 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr2_+_36230426 0.359 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr7_-_115846080 0.345 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr14_+_53324632 0.337 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr12_-_98259416 0.333 ENSMUST00000021390.7
Galc
galactosylceramidase
chr6_-_144209558 0.332 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr6_-_144209448 0.321 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr12_-_84617326 0.318 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr6_-_144209471 0.318 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chrX_+_106027300 0.302 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chrX_+_106027259 0.296 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr3_+_137341067 0.291 ENSMUST00000122064.1
Emcn
endomucin
chrX_-_102505359 0.288 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr11_+_97029925 0.288 ENSMUST00000021249.4
Scrn2
secernin 2
chr9_-_124304718 0.278 ENSMUST00000071300.6
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr7_-_101845300 0.278 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr3_+_88716838 0.276 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr14_+_55560010 0.273 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr17_+_45734506 0.268 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr12_-_56345862 0.260 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr17_+_40115358 0.257 ENSMUST00000061746.7
Gm7148
predicted gene 7148
chr17_-_45599603 0.250 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr14_-_57133585 0.247 ENSMUST00000039380.8
Gjb6
gap junction protein, beta 6
chr3_+_88716884 0.245 ENSMUST00000172252.1
Rit1
Ras-like without CAAX 1
chr13_-_106847267 0.228 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr17_+_14943184 0.204 ENSMUST00000052691.8
ENSMUST00000164837.2
ENSMUST00000174004.1
1600012H06Rik


RIKEN cDNA 1600012H06 gene


chr7_-_5413145 0.202 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr2_+_119047129 0.196 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr2_-_73580288 0.193 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr2_+_110597298 0.190 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr3_+_32708546 0.184 ENSMUST00000029214.7
Actl6a
actin-like 6A
chrM_+_2743 0.182 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr7_-_84679346 0.177 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr8_-_8690493 0.171 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chrX_-_74393003 0.168 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr2_-_28583189 0.156 ENSMUST00000113889.2
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr13_-_4609122 0.155 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr3_+_121953213 0.150 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr18_-_73754457 0.148 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr3_-_146495115 0.146 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr10_-_76110956 0.145 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr9_+_78191966 0.143 ENSMUST00000034903.5
Gsta4
glutathione S-transferase, alpha 4
chr10_-_86011833 0.141 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr9_-_15301555 0.128 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr15_+_85510812 0.124 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr8_+_34054622 0.124 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr16_+_21794320 0.121 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr7_+_39588931 0.119 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr2_-_28583239 0.118 ENSMUST00000028157.8
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr12_+_80463095 0.116 ENSMUST00000038185.8
Exd2
exonuclease 3'-5' domain containing 2
chr7_-_38019505 0.114 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr18_-_34579072 0.110 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr18_-_66002612 0.099 ENSMUST00000120461.1
ENSMUST00000048260.7
Lman1

lectin, mannose-binding, 1

chr4_-_11254248 0.098 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr17_-_32822200 0.098 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr3_+_32436376 0.095 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_-_133610253 0.094 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr7_-_42706369 0.094 ENSMUST00000180131.1
Gm17067
predicted gene 17067
chr2_-_67194695 0.093 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr5_-_65428354 0.089 ENSMUST00000131263.1
Ugdh
UDP-glucose dehydrogenase
chr13_+_23555023 0.085 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr2_-_119662756 0.085 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr3_+_32436151 0.081 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr2_+_121506748 0.066 ENSMUST00000099473.3
ENSMUST00000110602.2
Wdr76

WD repeat domain 76

chr4_-_92191749 0.065 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr2_+_69789647 0.061 ENSMUST00000112266.1
Phospho2
phosphatase, orphan 2
chr15_+_80711292 0.059 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr6_-_129533267 0.056 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr2_-_155930018 0.055 ENSMUST00000152766.1
ENSMUST00000139232.1
ENSMUST00000109632.1
ENSMUST00000006036.6
ENSMUST00000142655.1
ENSMUST00000159238.1
Uqcc1





ubiquinol-cytochrome c reductase complex assembly factor 1





chr7_-_19573343 0.054 ENSMUST00000051364.3
Gemin7
gem (nuclear organelle) associated protein 7
chr9_-_53667429 0.053 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr12_+_36314160 0.052 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr16_-_59553970 0.050 ENSMUST00000139989.1
Crybg3
beta-gamma crystallin domain containing 3
chr10_-_127030789 0.049 ENSMUST00000120547.1
ENSMUST00000152054.1
Tsfm

Ts translation elongation factor, mitochondrial

chr2_-_34826071 0.049 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr2_+_144594054 0.049 ENSMUST00000136628.1
Gm561
predicted gene 561
chr2_-_12419456 0.046 ENSMUST00000154899.1
ENSMUST00000028105.6
Fam188a

family with sequence similarity 188, member A

chr3_-_130730375 0.045 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr6_+_17749170 0.044 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr4_-_150914401 0.043 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chrX_-_160138375 0.043 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr12_-_87388317 0.042 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr13_+_94976435 0.041 ENSMUST00000160409.1
ENSMUST00000159647.1
ENSMUST00000167155.1
Wdr41


WD repeat domain 41


chr10_+_128322443 0.040 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr10_+_20347788 0.040 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr17_-_78684262 0.039 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr15_+_99295087 0.037 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr12_+_84285232 0.035 ENSMUST00000123614.1
ENSMUST00000147363.1
ENSMUST00000135001.1
ENSMUST00000146377.1
Ptgr2



prostaglandin reductase 2



chr10_-_49783259 0.032 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr10_+_52022502 0.031 ENSMUST00000163017.1
ENSMUST00000058347.4
Vgll2

vestigial like 2 homolog (Drosophila)

chr12_-_12940600 0.031 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr6_+_66896480 0.029 ENSMUST00000114222.1
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr14_+_118137101 0.027 ENSMUST00000022728.2
Gpr180
G protein-coupled receptor 180
chr14_-_18893376 0.023 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr10_-_53647080 0.021 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr4_-_155645408 0.019 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr4_+_126609818 0.017 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr6_+_66896397 0.016 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr5_+_135009152 0.015 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr1_-_63176653 0.014 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr12_-_54999102 0.010 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr17_-_56036546 0.010 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chr8_+_45507768 0.010 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr3_+_106034661 0.006 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr4_+_147492417 0.002 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr18_-_6241486 0.001 ENSMUST00000025083.7
Kif5b
kinesin family member 5B

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.3 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.3 1.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.2 0.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.6 GO:1904959 elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 1.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.2 1.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 1.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.6 GO:0070295 renal water absorption(GO:0070295)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.2 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.1 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 2.9 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.5 GO:0015816 glycine transport(GO:0015816)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.0 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation(GO:0018307) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) regulation of cellular amino acid biosynthetic process(GO:2000282) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 1.7 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 5.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.4 1.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 0.6 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2 1.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 6.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.7 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism